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Neural pathways of embarrassment and their modulation by social anxiety
2015
NeuroImage
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Targeting these neural markers of embarrassment in the (para-)limbic system provides new perspectives for developing treatment strategies for social anxiety disorders. ...
The converging integration of information from mentalizing areas and arousal processing systems within the ventral anterior insula and amygdala forms the neural pathways of embarrassment. ...
(PhD scholarship for SF and grant), the von Behring-Röntgen-Stiftung (KR 60-0023), and by The Netherlands Organization for Scientific Research (NWO; VENI Grant 451-09-006 to VG). ...
doi:10.1016/j.neuroimage.2015.06.036
pmid:26093329
pmcid:PMC5008438
fatcat:q2rxrzuvire3vg523omurlthtq
Oxytocin Facilitates Empathic- and Self-embarrassment Ratings by Attenuating Amygdala and Anterior Insula Responses
2018
Frontiers in Endocrinology
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and neural responses to embarrassment experienced by others or by self. ...
The neural effects of oxytocin were more pronounced stronger in individuals with high trait anxiety suggesting that it may particularly reduce their anxiety in embarrassing situations. ...
ACKNOWLEDGMENTS This study was supported by the National Natural Science Foundation of China (NSFC) grant 563 (grants 31530032; 91632117), the Fundamental Research Funds for the Central Universities of ...
doi:10.3389/fendo.2018.00572
fatcat:bhof6mjtgvftpf6sep6zo7fcbu
Oxytocin facilitates empathic- and self-embarrassment ratings by attenuating amygdala and anterior insula responses
[article]
2018
bioRxiv
pre-print
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and neural responses to embarrassment experienced by others or by self. ...
The neural effects of oxytocin are also stronger in individuals with high trait anxiety suggesting that it may particularly reduce their anxiety in embarrassing situations. ...
The neural effects of embarrassment are also modulated by anxiety (Mueller-Prinzler et al., 2015) and autism (Krach et al., 2016) . ...
doi:10.1101/343616
fatcat:loefnywekjbw7ly66qtkawbjbq
Gaining insight into adolescent vulnerability for social anxiety from developmental cognitive neuroscience
2014
Developmental Cognitive Neuroscience
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Yet some degree of social anxiety can be normative and non-impairing. ...
One fruitful approach taken to understand the mechanisms of social anxiety has been to use neuroimaging to link affect and cognition with neural networks implicated in the neurodevelopmental social reorientation ...
Acknowledgements This work was supported by National Institute of Health grants to A.E.G. (R00-MH080076) and to J.D.C. (T32-MH020006).The authors wish to thank Dr. Daniel S. Pine and Dr. ...
doi:10.1016/j.dcn.2013.10.003
pmid:24239049
pmcid:PMC3960349
fatcat:n6wa2xjvmnfhdhu4aap7ormggm
Social Circuits: Peptidergic Regulation of Mammalian Social Behavior
2005
Neuron
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Neural pathways the neurobiology of social behavior in diverse mammaemploying the nonapeptides vasopressin and oxytolian species is experimentally tractable and relevant to cin play a particularly prominent ...
over the last decade, indicating that sights into their neural substrates. ...
to wonder whether the neural pathways and cance, so can species differences in the action of these neuropeptides. ...
doi:10.1016/j.neuron.2005.08.004
pmid:16102531
fatcat:zwcpego6tfgwrmfni4va4uyfka
Editorial: Neuroendocrine Research in Health and Disease
2020
Frontiers in Neuroscience
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Eiden, and James A. Carr for participation in the editorial process and Dr. Benjamin C. Nephew and the many other reviewers for their valuable contributions to the quality of our accepted papers. ...
Interestingly, the neural effects of OT are stronger in individuals with high trait anxiety, suggesting that they may particularly reduce their anxiety in embarrassing situations. ...
A paper by Cheng et al. demonstrated that androgens and androgenic signaling are involved in the occurrence of depression and anxiety. ...
doi:10.3389/fnins.2020.00176
pmid:32265620
pmcid:PMC7105775
fatcat:airetbnzojb37kep3mxbv5z25i
Shame in Parkinson'S Disease: A Review
2019
Journal of Parkinson's Disease
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Shame is a self-conscious emotion marked by an intensely negative self-evaluation. It is exhibited by an individual upon realizing that she/he has violated an important (usually social) norm. ...
Shame can be a source of emotional distress leading to social withdrawal and depression, with a significant negative impact on quality of life. In Parkinson's disease (PD), shame is rarely addressed. ...
This mode of defense is a known pathway to severe depression and suicide, the most common risk factors for suicidal ideation being hopelessness, depression and social isolation [75] . ...
doi:10.3233/jpd-181462
pmid:31081792
pmcid:PMC6700625
fatcat:nm5yy5r2abhxfpfjgie2spf3my
Toward an integrative understanding of social phobia
2001
Journal of Psychiatry & Neuroscience
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The biologic distinctiveness of social phobia from anxiety disorders and physiological validation of differences between generalized and discrete social phobia subtypes have been implicated in genetic, ...
understanding of social phobia in the framework of a hypothetical neural circuit. ...
Introduction Social phobia (SP), also termed social anxiety disorder, is a disorder characterized by extreme anxiety in social and performance situations. ...
pmid:11394189
pmcid:PMC1408296
fatcat:364v3dqcinb6dijpxhj6xnzvqm
Social Impairments in Mental Disorders: Recent Developments in Studying the Mechanisms of Interactive Behavior
2019
Clinical Psychology in Europe
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in Autism Spectrum Disorder (ASD), Personality Disorder, Social Anxiety Disorder (SAD), and Schizophrenia. ...
In individuals with ASD, these methods revealed reduced sensitivity to the presence of a real interaction partner as well as diminished behavioral and neural synchronicity with interaction partners. ...
Author Contributions: The first and second author contributed equally to this work. ...
doi:10.32872/cpe.v1i2.33143
fatcat:zxnibbidkvc5hgg6bmnyebjum4
Molecular and neurocircuitry mechanisms of social avoidance
2020
Cellular and Molecular Life Sciences (CMLS)
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Humans and animals live in social relationships shaped by actions of approach and avoidance. Both are crucial for normal physical and mental development, survival, and well-being. ...
Active withdrawal from social interaction is often induced by the perception of threat or unpleasant social experience and relies on adaptive mechanisms within neuronal networks associated with social ...
Within this framework, avoidant responses are modulated by subjects' level of anxiety and by previous episodes of social stress. ...
doi:10.1007/s00018-020-03649-x
pmid:32997200
fatcat:thtvj6yei5cr3ein6g3lzkobte
OFC and its connectivity with amygdala as predictors for future social anxiety in adolescents
2020
Developmental Cognitive Neuroscience
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Mediation analysis revealed that the relationship between social anxiety and attention avoidance is partly mediated by the FC of OFC-amygdala. ...
The present study investigated the neural basis of social anxiety using voxel-based morphometry (VBM) and functional connectivity analysis. ...
However, little is known about the neural and cognitive basis of social anxiety in adolescents. ...
doi:10.1016/j.dcn.2020.100804
pmid:32716853
pmcid:PMC7301179
fatcat:npmt5p5eardrjjgsujky5sm3ye
Treatment Options for Fear of Blushing
2020
Current Psychiatry Reports
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Psychological risk factors for fear of blushing include social anxiety, coupled with heightened self-focused attention and inflated beliefs about the likelihood and social costs of blushing. ...
However, selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors are effective treatments for social anxiety disorder and may thus help some patients manage their fear ...
Such people assess their social performance by relying on these biased appraisals; thus, negative perceptual bias is thought to be important for maintaining social anxiety and fear of blushing. ...
doi:10.1007/s11920-020-01152-5
pmid:32377882
fatcat:a65ciozoorfqfbm2gwv3ca6smu
A REVIEW ON THE NEURAL CIRCUITS IN ANXIETY DISORDERS
2016
Asian Journal of Pharmaceutical and Clinical Research
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,poor coping skills, palpitation, sweating, agoraphobia, and social withdrawal. ...
Anxiety disorders are characterized by alterationsin a diverse range of neurochemical systems, suggesting ample novel targets for drug therapies. ...
NEURAL CIRCUITS INVOLVED IN ANXIETY The neurobiology of anxiety disorders is not fully understood, but several different biologic abnormalities have been implicated in their etiology [44] . ...
doi:10.22159/ajpcr.2016.v9s3.11820
fatcat:s5xgsd5manhihe2e3uwigmi4se
Watch and Learn: Vicarious Threat Learning across Human Development
2021
Brain Sciences
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Next, we focus on the social factors influencing vicarious threat learning; this is followed by a review of vicarious threat learning among children and adolescents. ...
To conclude, we encourage future research directions that will help elucidate how vicarious threat learning emerges and how it relates to the development of normative fear and pathological anxiety. ...
Conflicts of Interest: The authors declare no conflict of interest. ...
doi:10.3390/brainsci11101345
pmid:34679409
fatcat:bb7j7ur6pfhmpgw6czdlkaaqbi
"Update to Pseudobulbar affect (suddenly emotions of crying/laughing without control)"
2021
American Journal of Biomedical Science & Research
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Low levels of "serotonin" in the brain may cause depression, anxiety, and sleep trouble. And many other neurotransmitters types are used in the synapses in the neural pathways. ...
circuits known as: "neural pathways". ...
doi:10.34297/ajbsr.2021.13.001837
fatcat:4tpw75zdfvaunoukyn4cf3q7nu
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