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Neocortical reorganization in spina bifida
2008
NeuroImage
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We investigated total cerebral volumes, neocortical surface area, and neocortical thickness in 16 children with a neural tube defect, spina bifida myelomeningocele (SB), and 16 age-matched typically developing ...
Group comparisons of neocortical surface area assessments were significantly smaller in the occipital regions for SB, with no significant group differences in the frontal regions. ...
We wish to thank Vipul Kumar Patel for assistance with MRI data acquisition and Amy Walker Hampson for recruitment of spina bifida participants. ...
doi:10.1016/j.neuroimage.2008.01.043
pmid:18337124
pmcid:PMC2410089
fatcat:kcsr57jhqvbezk66cqchymakaq
Spina bifida
2015
Nature Reviews Disease Primers
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Spina bifida is a birth defect in which the vertebral column is open (bifid), often with spinal cord involvement. ...
Clinically most significant is myelomeningocele (MMC; open spina bifida) in which the spinal neural tube fails to close during embryonic development. ...
Neocortical reorganization in spina bifida. Neuroimage. 2008; 40:1516-1522. [PubMed: 18337124] 54. Del Bigio MR. Neuropathology and structural changes in hydrocephalus. ...
doi:10.1038/nrdp.2015.7
pmid:27189655
pmcid:PMC4898641
fatcat:yr3y52r3wvhchnenf7mzpos2gu
Etiology and Pathophysiology of the Spina Bifida
[chapter]
2021
Spina Bifida and Craniosynostosis - New Perspectives and Clinical Applications [Working Title]
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The spina bifida is a congenital anomaly that results in an abnormal formation of the spine and the spinal cord. ...
Genetic, nutritional and environmental factors play a role in the etiology and pathogenesis of the spina bifida. ...
Overall reduction in white matter and increased neocortical thickness in the frontal lobes suggest that the spina bifida reflects a long-term disruption of brain development that extends far beyond the ...
doi:10.5772/intechopen.97467
fatcat:yqvr5uazo5corl5gtjzvde4xxi
Partial agenesis of the corpus callosum in spina bifida meningomyelocele and potential compensatory mechanisms
2009
Journal of Clinical and Experimental Neuropsychology
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CC agenesis, and the results of an examination of magnetic resonance imaging (MRI) data of the CC in 193 children with spina bifida meningomyelocele (SBM). ...
The hippocampal commissure, enlarged in 13%, may be a more promising candidate. Overall, however, the functionality of anomalous fiber tracts and commissures in SBM is yet to be determined. ...
Acknowledgments This research was funded by National Institutes of Child Health and Human Development Grant PO1 HD35946, "Spina Bifida: Cognitive and Neurobehavioral Variability." ...
doi:10.1080/13803390802209954
pmid:19052950
pmcid:PMC2692259
fatcat:e32j3n5epjf6ze2pakuuhgbqka
Age, plasticity, and homeostasis in childhood brain disorders
2013
Neuroscience and Biobehavioral Reviews
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Cerebellar resculpting in spina bifida meningomyelocele, on the other hand, may promote increased functionality of eye movements. ...
Hyperdevelopment of the midsagittal vermis in spina bifida meningomyelocele is associated with sparing of ocular motor function (Salman, Dennis, & Sharpe, 2009 ). ...
doi:10.1016/j.neubiorev.2013.09.010
pmid:24096190
pmcid:PMC3859812
fatcat:gp2x5shfh5fz5bses55org7kpq
Brain mechanisms for reading and language processing in spina bifida meningomyelocele: A combined magnetic source- and structural magnetic resonance imaging study
2011
Neuropsychology
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The present study explored features of brain organization in children with spina bifida meningomyelocele (SBM) and shunted hydrocephalus, who commonly present with precocious development of word reading ...
Conclusions: A complex pattern of changes in cortical morphology and activation may serve as evidence for structural and functional brain reorganization ensuring preservation of language and decoding abilities ...
Spina bifida was verified by medical review of pathology and neurosurgical operative reports. ...
doi:10.1037/a0023694
pmid:21574714
pmcid:PMC3175695
fatcat:sesbb4u5jrcxlc3ptzcue63uoa
Wnt signaling in development and disease
2010
Neurobiology of Disease
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Dvl2 null mutants have thoracic spina bifida and Dvl1/2 double mutants produce even more severe NTD (Hamblet et al., 2002) . ...
LRP6 mutant mice exhibit neocortical defects that are consistent with an essential role for canonical Wnt signaling in the neocortical VZ (Zhou et al., 2004b) . ...
doi:10.1016/j.nbd.2009.09.003
pmid:19765659
pmcid:PMC2854277
fatcat:wy5yinijs5by7k7czdh2pjefgq
Zagreb research collection of human brains for developmental neurobiologists and clinical neuroscientists
1991
International Journal of Developmental Biology
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We concluded that structural remodeling and reorganization of the brain, from the transient patterns of the fetal organization through the postnatal phase of transient overproduction of circuitry elements ...
evidence concerning the timing and pattern of development of afferent fiber systems in the human cortex. ...
bifida), brains of fetuses and infants with trisomy syndromes (Down's syndrome, Syndroma Patau and Syndroma Edwards). ...
pmid:1687658
fatcat:2bcjtwwrajcdjnhnaszz5potsu
Page 269 of Psychological Abstracts Vol. 87, Issue Subject Index
[page]
Psychological Abstracts
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Volume 87 SUBJECT INDEX
development & organization of corpus callosum & cogni- tive functioning, children with early hydrocephalus re- sulting in spina bifida or aqueductal stenosis or prematurity-intraventricular ...
memory for normal vs distorted pictures, 19-30 yr olds, 7037
motor control reorganization in abductor pollicis brevis & abductor digiti minimi muscles, motor cortical EPs, 40 yr old male with mirror movements ...
MJMS at the Dawn of Its Electronic Era
2011
Malaysian Journal of Medical Sciences
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In addition, we also discussed the future directions of MJMS. ...
This special editorial assessed the recent developments in Malaysian Journal of Medical Sciences (MJMS) and examined the characteristics of the submission, peer review, and publication processes for MJMS ...
Malaysia (IIUM), for their continuous effort and assistance in the care and treatment of the patients. ...
pmid:22135566
pmcid:PMC3216199
fatcat:t7qjful37nftdl7q3itniobxwi
Applying evolutionary genetics to developmental toxicology and risk assessment
2017
Reproductive Toxicology
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in vitro and whole-organism models. ...
Yet, there is a communication gap between evolutionary biologists and toxicologists in recognizing the connections among developmental pathways, high-throughput screening, and birth defects in humans. ...
bifida), and so forth (Thorogood 1997; Epstein 2008) . ...
doi:10.1016/j.reprotox.2017.03.003
pmid:28267574
pmcid:PMC5829367
fatcat:3syrlt3m4bc3xn2b5dg73aojhu
Neuroimaging of typical and atypical development: A perspective from multiple levels of analysis
2002
Development and Psychopathology
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in interregional interactions rather than searching for localized, discrete lesions; examine the temporal dynamics of neural processing; and move away from deficits to image tasks in which atypical participants ...
This alternative view, based on an "interactive specialization" approach to postnatal brain development, indicates that there is a need to: obtain data from early in development; focus more on differences ...
How-terations in brain development are spina bifida and anencephaly, in which the gross mor-ever, with a few exceptions, these large-scale regions generally do not map onto the detailed phology of the ...
doi:10.1017/s0954579402003073
fatcat:q6ae44f7nvfnbjgmgocbajddei
Mena and Vasodilator-Stimulated Phosphoprotein Are Required for Multiple Actin-Dependent Processes That Shape the Vertebrate Nervous System
2004
Journal of Neuroscience
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Mice deficient in either Mena or VASP exhibit subtle defects in forebrain commissure formation and platelet aggregation, respectively. ...
In this study, we investigated the consequence of deleting both Mena and VASP. ...
Neurulation defects in M Ϫ/Ϫ V Ϫ/Ϫ mice are restricted to the cephalic neural tube, resulting in exencephaly but not spina bifida. ...
doi:10.1523/jneurosci.1057-04.2004
pmid:15371503
fatcat:w64p4picwvgdhck5uccgajy2qq
World Journal of Pharmacy and Biotechnology A Review on Epilepsy
2015
WJPBT
unpublished
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The brain is involved in nearly every bodily function, including the higher cortical functions. ...
If the affected cortical network is in the visual cortex, the clinical manifestations are visual phenomena. ...
Patients on valproate or carbamazepine need careful screening to detect spina bifida. ...
fatcat:yvx3cmxdxnevpj65eyxcen3vri
Final Program, Thirty-Eighth Annual Meeting International Neuropsychological Society
2010
Journal of the International Neuropsychological Society
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Although left distraction increased leftward errors in both groups, "where" distraction bias was more leftward in controls, and in pAD subjects, left distraction was associated with decreased rightward ...
Conclusions: We found "where" left-sided distraction in controls was not observed in pAD, rather left-sided distraction potentially influenced "aiming" bias. ...
Executive Functions and Self-Care Initiation in Adolescents and Young Adults With Spina Bifida. Objective: Executive functioning deficits have been well-documented in youth with Spina Bifida (SB). ...
doi:10.1017/s1355617710000226
fatcat:cvsuvca32nhnbf3f66rmxq7eiq
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