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NEZHA: Efficient Domain-Independent Differential Testing
2017
2017 IEEE Symposium on Security and Privacy (SP)
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Based on δ-diversity, we design two efficient domain-independent input generation mechanisms for differential testing, one gray-box and one blackbox. ...
In this paper, we address these issues by designing and implementing NEZHA, an efficient input-formatagnostic differential testing framework. ...
One may argue that being domain-independent, NEZHA may not be as efficient as successful domain-specific frameworks. ...
doi:10.1109/sp.2017.27
dblp:conf/sp/PetsiosTSKJ17
fatcat:j3poc4sdnbftne7svn4pl2clhq
Coverage-guided differential testing of TLS implementations based on syntax mutation
2022
PLoS ONE
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Researchers are attempting to find the differences in protocol implementations based on differential testing, which is conducive to discovering the vulnerabilities. ...
The proposed method is developed based on open-source tools, i.e., NEZHA and TLS-diff. ...
For the TLS handshake process, the mutation efficiency is reduced due to the independence of the domain of NEZHA and the strong structure of the data packet. ...
doi:10.1371/journal.pone.0262176
pmid:35073360
pmcid:PMC8786154
fatcat:2ol6csi32ndqhns4tuenihbuba
CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions
2013
Journal of Cell Biology
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Interestingly, both CLASP2 and Nezha interact with p120 through the N-terminal domain, but we found Nezha localized in the suprabasal differentiated layers of the epidermis, in which MTs are substantially ...
Nezha localizes in the suprabasal differentiated layers of the epidermis, probably interacting with p120. DP, desmoplakin.
(n = 16 cells, 5 profiles per cell, 3 independent experiments). ...
doi:10.1083/jcb.201306019
pmid:24368809
pmcid:PMC3871427
fatcat:4slh65j66ndhtbq5dxsgzgxqmq
Microtubule Minus-End-Targeting Proteins
2015
Current Biology
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The recent characterization of the CAMSAP/Patronin/Nezha family members as specific 'minus-end-targeting proteins' ('-TIPs') has provided important new insights into the mechanisms governing minus-end ...
current state of knowledge on how microtubule minus ends are controlled and how minus-end regulators contribute to non-centrosomal microtubule organization and function during cell division, migration and differentiation ...
CAMSAP/Patronin/Nezha Family Proteins are Specific Microtubule Minus-end Regulators The CAMSAP/Patronin/Nezha family is characterized by the presence of the signature domain CKK (which stands for C-terminal ...
doi:10.1016/j.cub.2014.12.027
pmid:25689915
fatcat:lcx747fkurfcffkmyw2u5xvccm
Regulation of microtubule minus-end dynamics by CAMSAPs and Patronin
2014
Proceedings of the National Academy of Sciences of the United States of America
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However, we find that, in both cases, a highly conserved C-terminal domain and a more variable central domain cooperate to suppress minus-end dynamics in vitro and that both regions are required to stabilize ...
By using truncation analysis, we find that somewhat different minimal domains of CAMSAP and Patronin are involved in minus-end localization. ...
Results compiled from two independent experiments (>100 MTs scored per assay).
Fig. 2 .Fig. 3 . 23 CAMSAPs differentially affect tubulin subunit addition at MT minusends. ...
doi:10.1073/pnas.1404133111
pmid:24706919
pmcid:PMC4000804
fatcat:zcydwd5zpzez7i3larws3yziii
SAM 2020 Conference Program
2020
2020 IEEE 11th Sensor Array and Multichannel Signal Processing Workshop (SAM)
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Researcher, USA) MIMO Radar Waveform Joint Optimization Design in Time and Frequency Domain Chu Chun-hua (Institute of Information and Navigation, Air Force Enginnering University, China); Yijun Chen ...
II, Italy); Luca Venturino (Universita' degli Studi di Cassino e del Lazio Merdionale & Consorzio Nazionale Interuniversitario per le Telecomunicazioni (CNIT), Italy)Persymmetric Subspace Rao and Wald Tests ...
doi:10.1109/sam48682.2020.9104325
fatcat:axqtfgjaunaw7dix4b2fzqvkh4
SAM 2020 Author Index
2020
2020 IEEE 11th Sensor Array and Multichannel Signal Processing Workshop (SAM)
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Differential Microphone Arrays
Comon, Pierre
SS12.3
On the convergence of Jacobi-type algorithms for
Independent Component Analysis
Cong, Jingyu
SS01.5
Feasible Spare Spectrum Fitting for DOA ...
, Yanan
SS11.3
Enhanced DOA Estimation for MIMO radar in the
Case of Limited Snapshots
Ma, Yirong
R06.4
Hyperspectral Image Clustering based on Variational
Expectation Maximization
Mamouni, Nezha ...
doi:10.1109/sam48682.2020.9104397
fatcat:cfp5gsikrzabhhcnkalahjkxze
PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins
2016
Journal of Biological Chemistry
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PDZD11 is required for the efficient assembly of apical junctions of epithelial cells at early time points in the calcium-switch model. ...
PDZD11 forms a complex with nectin-1 and nectin-3, and its PDZ domain interacts directly with the PDZ-binding motif of nectin-1. ...
Afadin/␣-catenin and nezha provide the linkage of the complexes to actin filaments and microtubules, respectively. ...
doi:10.1074/jbc.m115.712935
pmid:27044745
pmcid:PMC4900252
fatcat:bb3mqc7p4zeojhwvyjf4ds4ma4
Microtubule Minus-End Stabilization by Polymerization-Driven CAMSAP Deposition
2014
Developmental Cell
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Here, we focus on the mechanisms underlying the regulation of microtubule minus-ends by the CAMSAP/Nezha/Patronin protein family. ...
The plot is based on three independent experiments. Error bars represent SD. **p < 0.01, t test. ...
t test. ...
doi:10.1016/j.devcel.2014.01.001
pmid:24486153
fatcat:qq2wsexcezardc4zi4rrv34efe
Role of the microtubule-targeting drug vinflunine on cell-cell adhesions in bladder epithelial tumour cells
2014
BMC Cancer
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Results: We show that VFL induces cell death in bladder cancer cells and activates epithelial differentiation of the remaining living cells, leading to an increase of E-cadherin-dependent cell-cell adhesion ...
It contains an extracellular domain that forms homophilic interactions in a calcium-dependent manner and is responsible for cell-to-cell adhesions, and a cytoplasmic domain linked to the actin cytoskeleton ...
In cultured mammalian epithelial cells, depletion of either Nezha or PLEKHA7, which is responsible for recruiting Nezha to p120-ctn, disrupted the ability of cells to concentrate E-cadherin to the apical ...
doi:10.1186/1471-2407-14-507
pmid:25012153
pmcid:PMC4107965
fatcat:zwwlwqzkejaghpqilbcrscxtzu
Developmental Trajectories of Associative Memory from Childhood to Adulthood: A Behavioral and Neuroimaging Study
2013
Frontiers in Behavioral Neuroscience
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Behavioral data outlined differential developmental trajectories according to the type of association, with a continuous increase of factual associative memory efficiency until 10 years, a linear increase ...
We conducted a behavioral study aimed at testing the effects of age in a large sample of 160 children, adolescents, and young adults (6-23 years old). ...
ACKNOWLEDGMENTS We would like to thank Valerie Gyselinck and Maud Markus for their contribution to the WHAT-WHERE-WHEN paradigm development, and Nezha Bissara, and Lionel Allirol for their assistance with ...
doi:10.3389/fnbeh.2013.00126
pmid:24098276
pmcid:PMC3784827
fatcat:d63dtjpfsjacbp4ptabd5d4bra
Microtubule Minus-End Binding Protein CAMSAP2 Controls Axon Specification and Dendrite Development
2014
Neuron
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Using live-cell imaging, high-resolution microscopy, and laser-based microsurgery techniques, we show that the CAMSAP/Nezha/Patronin family protein CAMSAP2 specifically localizes to noncentrosomal microtubule ...
The efficiency of CAMSAP2 protein depletion was tested by introducing two independent CAMSAP2 shRNAs into neuronal cultures by lentiviral transduction. ...
These findings show that the minimal CAMSAP2 minus-end binding domain is not sufficient to restore dendrite morphology, suggesting that additional domains of CAMSAP2 are critical for CAMSAP2 function. ...
doi:10.1016/j.neuron.2014.04.019
pmid:24908486
fatcat:sgwzpfsufrb37gnvff7nqkdwde
Functions of p120ctn in development and disease
2012
Frontiers in Bioscience
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Differential regulation of RhoGTPases by p120ctn in cancer 9.4. p120ctn isoforms: effects on proliferation and tumor growth 9.5. p120ctn isoforms: effects on motility and invasion 9.6. p120ctn and anchorage-independent ...
p120ctn and anchorage-independent growth Anchorage-independent growth (AIG) is a hallmark of tumor formation and is dependent on endogenous p120ctn. ...
The p120ctn-depleted cells have been employed for testing the potential of different p120ctn isoforms to induce invasion. ...
doi:10.2741/3956
pmid:22201773
fatcat:3w6olwcdu5dpfeec44hmzrpjli
Control of apico–basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7
2016
Journal of Cell Science
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For knockdown efficiency tests, fluorescence intensity was measured per cell and corrected for the cell surface area using ImageJ 1.50b. ...
., 2007) and by proteins that bind to microtubule minus ends independently of γ-tubulin. ...
doi:10.1242/jcs.194878
pmid:27802168
fatcat:ezpo73jadfeitdqm7mrclykqxm
Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling
2012
Frontiers in Bioscience
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When TLR4 binds LPS, it activates the MyD88-dependent and MyD88-independent pathways. ...
These p120ctn-depleted cell lines are also suitable for testing the effect of various p120ctn isoforms on RhoA activity. ...
doi:10.2741/4012
pmid:22201829
fatcat:2v7ayvaawveu5mrrrmq24rtxue
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