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Blood Stream Infections by Candida glabrata and Candida krusei: A Single-Center Experience

Hee Kyoung Choi, Su Jin Jeong, Han Sung Lee, Bum Sik Chin, Suk Hoon Choi, Sang Hoon Han, Myung Soo Kim, Chang Oh Kim, Jun Yong Choi, Young Goo Song, June Myung Kim
2009 The Korean Journal of Internal Medicine  
Choi HK, et al.  ... 
doi:10.3904/kjim.2009.24.3.263 pmid:19721864 pmcid:PMC2732787 fatcat:o4kazeknpvec5pnwex5sk5kfzq

Motion patches

Kang Hoon Lee, Myung Geol Choi, Jehee Lee
2006 ACM Transactions on Graphics  
., body and footprint locations) and randomized sampling techniques for producing character animation of locomotion, crawling, and climbing [Choi et al. 2003; Kalisiak and van de Panne 2001; Kuffner et  ... 
doi:10.1145/1141911.1141972 fatcat:peyz55ujpjauji4v3pq6d3idfu

Utility of QuantiFERON-TB In-Tube Test for Differentiating Active Tuberculosis from Latent Tuberculosis Infection in an Intermediate Burden Country

Suk Hoon Choi, Bum Sik Chin, Sang Hoon Han, Han Sung Lee, Chang Oh Kim, Su Jin Jeong, Hee Kyung Choi, Myung Soo Kim, Jun Yong Choi, Young Goo Song, June Myung Kim
2008 Infection & Chemotherapy  
These included a whole-blood IFN-γ enzyme-linked immunosorbent assay (ELISA) and an enzyme-linked immunospot assay Submitted : 18 July 2008, Accepted : 16 October 2008 Correspondence : June Myung Kim,  ... 
doi:10.3947/ic.2008.40.6.305 fatcat:rqwem3q77rhozal3d3fbdxvl5a

Factors Associated with HIV-1 Proviral DNA Loads in Patients with Undetectable Plasma RNA Load

Jun Yong Choi, Young Goo Song, Young Hwa Kim, Chang Oh Kim, Myung Soo Kim, Bum Sik Chin, Sang Hoon Han, Suk Hoon Choi, Han Sung Lee, Su Jin Jeong, Heekyoung Choi, June Myung Kim
2009 Journal of Korean medical science  
To evaluate factors associated with human immunodeficiency virus type 1 (HIV-1) proviral DNA load, we conducted a cross-sectional study of 36 chronically HIV-1infected individuals with undetectable plasma viral RNA. We used real-time polymerase chain reaction to determine the number of HIV-1 proviral DNA copies per 10 6 peripheral blood mononuclear cells. The mean level of plasma viral RNA when the CD4+ T cell count was above 500 cells/μ L without highly active antiretroviral therapy (HAART)
more » ... significantly associated with proviral DNA load at the time of undetectable plasma HIV RNA with HAART. Strategies to reduce the level of plasma viral RNA when patients' CD4+ T cell counts are above 500 cells/μ L without HAART could help reduce HIV-1 proviral DNA load.
doi:10.3346/jkms.2009.24.1.152 pmid:19270829 pmcid:PMC2650966 fatcat:r6puttwdcfgyvg4ks5ufso4vlu

Two Cases of Multidrug-Resistant Human Immunodeficiency Virus Infection Treated with Atazanavir and Lopinavir/Ritonavir Combination Therapy

Heekyoung Choi, Su Jin Jeong, Han Sung Lee, Bum Sik Chin, Suk Hoon Choi, Sang Hoon Han, Myung Soo Kim, Chang Oh Kim, Jun Yong Choi, Young Goo Song, June Myung Kim
2008 Journal of Korean medical science  
doi:10.3346/jkms.2008.23.4.737 pmid:18756069 pmcid:PMC2526394 fatcat:wu362lcuifbqvakmwtolmv3v6a

Motion patches

Kang Hoon Lee, Myung Geol Choi, Jehee Lee
2006 ACM SIGGRAPH 2006 Papers on - SIGGRAPH '06  
., body and footprint locations) and randomized sampling techniques for producing character animation of locomotion, crawling, and climbing [Choi et al. 2003; Kalisiak and van de Panne 2001; Kuffner et  ... 
doi:10.1145/1179352.1141972 fatcat:x4vrl7db2faonc4kcc5afx2zvq

Disseminated Mycobacterium kansasii Infection Associated with Skin Lesions: A Case Report and Comprehensive Review of the Literature

Sang Hoon Han, Kyoung Min Kim, Bum Sik Chin, Suk Hoon Choi, Han Sung Lee, Myung Soo Kim, Su Jin Jeong, Hee Kyoung Choi, Chang Oh Kim, Jun Yong Choi, Young Goo Song, June Myung Kim
2010 Journal of Korean medical science  
Mycobacteruim kansasii occasionally causes disseminated infection with poor outcome in immunocompromised patients. We report the first case of disseminated M. kansasii infection associated with multiple skin lesions in a 48-yr-old male with myelodysplastic syndrome. The patient continuously had taken glucocorticoid during 21 months and had multiple skin lesions developed before 9 months without complete resolution until admission. Skin and mediastinoscopic paratracheal lymph node (LN) biopsies
more » ... howed necrotizing granuloma with many acid-fast bacilli. M. kansasii was cultured from skin, sputum, and paratracheal LNs. The patient had been treated successfully with isoniazid, rifampin, ethmabutol, and clarithromycin, but died due to small bowel obstruction. Our case emphasizes that chronic skin lesions can lead to severe, disseminated M. kansasii infection in an immunocompromised patient. All available cases of disseminated M. kansasii infection in non HIV-infected patients reported since 1953 are comprehensively reviewed.
doi:10.3346/jkms.2010.25.2.304 pmid:20119588 pmcid:PMC2811302 fatcat:qgfjw2mqcvhhtffqdu6jvsxmbu

Colon Cancer After Acute Diverticulitis Treatment

Kwang Hoon Oh, Koon Hee Han, Eun Jung Kim, Je Hoon Lee, Kyu Un Choi, Myung Sik Han, Jae Hong Ahn, Gab Jin Cheon
2013 Annals of Coloproctology  
Diverticulitis is the most common clinical complication of diverticular disease, affecting 10-25% of the patients with diverticula. The prevalences of diverticulitis and colon cancer tend to increase with age and are higher in industrialized countries. Consequently, diverticulitis and colon cancer have been reported to have similar epidemiological characteristics. However, the relationship between these diseases remains controversial, as is the performance of routine colonoscopy after an
more » ... of diverticulitis to exclude colon cancer. Recently, we experienced three cases of colon cancer after treating acute diverticulitis, based on which we suggest the importance of follow-up colonoscopy after acute diverticulitis.
doi:10.3393/ac.2013.29.4.167 pmid:24032118 pmcid:PMC3767867 fatcat:tud3jgfz7fbffiomoqx5asjlym

Prognostic Implications of Portal Venous Circulating Tumor Cells in Resectable Pancreatic Cancer

Young Hoon Choi, Tae Ho Hong, Seung Bae Yoon, In Seok Lee, Myung Ah Lee, Ho Joong Choi, Moon Hyung Choi, Eun Sun Jung
2022 Biomedicines  
Circulating tumor cells (CTCs) are a promising prognostic biomarker for cancers. However, the paucity of CTCs in peripheral blood in early-stage cancer is a major challenge. Our study aimed to investigate whether portal venous CTCs can be a biomarker for early recurrence and poor prognosis in pancreatic cancer. Patients who underwent upfront curative surgery for resectable pancreatic cancer were consecutively enrolled in this prospective study. Intraoperatively, 7.5 mL of portal and peripheral
more » ... lood was collected, and CTC detection and identification were performed using immunofluorescence staining. Peripheral blood CTC sampling was performed in 33 patients, of which portal vein CTC sampling was performed in 28. The median portal venous CTCs (2.5, interquartile ranges (IQR) 1–7.75) were significantly higher than the median peripheral venous CTCs (1, IQR 0–2, p < 0.001). Higher stage and regional lymph node metastasis were related with a larger number of CTCs (≥3) in portal venous blood. Patients with low portal venous CTCs (≤2) showed better overall (p = 0.002) and recurrence-free (p = 0.007) survival than those with high portal venous CTCs (≥3). If validated, portal CTCs can be used as a prognostic biomarker in patients with resectable pancreatic cancer.
doi:10.3390/biomedicines10061289 pmid:35740311 pmcid:PMC9219704 fatcat:dmt3ddfourau3is45k2isjabd4

Diagnosis and Species Identification of Mycobacterial Infections by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Analysis of Sterile Body Fluids

Cheong Ho Cho, Sang Hoon Han, Bum Sik Chin, Suk Hoon Choi, Han Sung Lee, Chang Oh Kim, Myung Soo Kim, Jun Yong Choi, Young Goo Song, June Myung Kim
2009 The Korean Journal of Internal Medicine  
Background/Aims: The development of effective, accurate, and rapid diagnostic methods for Mycobacterium infection and mycobacterial species identification is required. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is an easy, rapid and inexpensive technique for identifying Mycobacterium spp. Methods: We performed PCR-RFLP to detect and identify Mycobacterium spp. from 10 sterile body fluids, including ascites, cerebrospinal fluid, pleural fluid, synovial fluid,
more » ... d peritoneal dialysis fluid. Clinical samples were collected from patients with diagnoses of definite, probable or suspected mycobacterial infection. The conserved RNA polymerase genes of Mycobacterium spp. were amplified by PCR. Results: The amplified 360-bp region of rpoB was digested with the restriction enzyme MspI or HaeIII. The PCR-RFLP results for the clinical samples were identical to those for M. tuberculosis, M. fortuitum, M. intracellulare, and M. avium. In addition, the results of the PCR-RFLP were identical to those obtained by DNA sequencing. Conclusions: PCR-RFLP analysis of sterile body fluids may be a useful method for the diagnosis of mycobacterial infections and for the differentiation of mycobacterial species. (Korean J Intern Med 2009;24:135-138)
doi:10.3904/kjim.2009.24.2.135 pmid:19543492 pmcid:PMC2698622 fatcat:oeokf4mrenarrea7rfszb7vnty

Electrorheology of conducting polyaniline composite particles

Hyoung Jin Choi, Min Sung Cho, Young Hoon Lee, Yun Hyang Cho, Myung S. Jhon
2004 E-Polymers  
AbstractThree different kinds of particles of semiconductive polyaniline (PANI), spherical poly(methyl methacrylate) with a PANI shell (PAPMMA), and conductive PANI encapsulated by insulating melamine-formaldehyde resin (MCPA) were synthesized and adopted as a dispersed phase for electrorheological (ER) fluids. ER fluids are suspensions of polarizable particles dispersed in non-conducting liquids. The rheological characteristics of ER fluids rapidly change in the presence of an applied electric
more » ... field, which can be controlled by both the applied electric field strength and particle concentration with a fast response time on the order of milliseconds. MCPA-based ER fluids show the largest stress enhancement by an applied electric field compared with both PANI- and PAPMMA-based ER fluids, demonstrating that the conductive core with an insulating shell system is a better ER material than homogeneous, semiconductive materials or surface-semiconductive materials with insulating cores.
doi:10.1515/epoly.2004.4.1.314 fatcat:e4j2fh2gtva2jjgzvpdafd5bve

Reduced cortical folding of the anterior cingulate cortex in obsessive-compulsive disorder

Geumsook Shim, Wi Hoon Jung, Jung-Seok Choi, Myung Hun Jung, Joon Hwan Jang, Ji-Young Park, Chi-Hoon Choi, Do-Hyung Kang, Jun Soo Kwon
2009 Journal of Psychiatry & Neuroscience  
Anterior cingulate cortex (ACC) abnormalities have been implicated consistently in the pathophysiology of obsessive-compulsive disorder (OCD), yet it remains unclear whether these abnormalities originated during early neurodevelopment. In this study, we examined the ACC sulcal/gyral patterns to investigate whether neurodevelopmental anomalies of the ACC were present in patients with OCD. We hypothesized that patients with OCD would show reduced cortical folding of the ACC compared with
more » ... We used magnetic resonance imaging (MRI) of 169 healthy volunteers and 110 patients with OCD to examine the paracingulate sulcus and cingulate sulcus. We assessed cortical folding patterns according to established classification criteria and constructed 3 categories of paracingulate sulcus morphology according to its presence and anteroposterior extent: "prominent," "present" and "absent." We classified the cingulate sulcus as "interrupted" or "continuous" according to the interruptions in its course. In addition, we evaluated ACC sulcal asymmetry based on interhemispheric comparisons of paracingulate sulcus morphology. Analyses revealed that patients with OCD were significantly less likely than controls to show a well-developed left paracingulate sulcus: 50.0% of patients and 65.1% of controls showed a "prominent" or "present" paracingulate sulcus in the left hemisphere. However, there were no differences in regard to cingulate sulcus continuity, and patients also showed the same leftward ACC sulcal asymmetry as controls. Our study was limited by the fact that we obtained the MRI scans from 2 different scanners, and we did not calculate cerebral fissurization as our study was restricted to 1 specific brain region. Moreover, patients and controls differed significantly in terms of sex ratio and IQ, although we controlled these variables as covariates. Our findings imply a subtle deviation in the early neurodevelopment of the ACC in patients with OCD, but the extent to which these anomalies contributed to the pathogenesis of OCD remains unclear. Further studies that link the ACC morphologic anomalies to the pathophysiology of OCD are recommended.
pmid:19949720 pmcid:PMC2783435 fatcat:xhxmytowevhbxgtacxqvxmabre

Cortical Thickness Reduction in Individuals at Ultra-High-Risk for Psychosis

Wi Hoon Jung, June Sic Kim, Joon Hwan Jang, Jung-Seok Choi, Myung Hun Jung, Ji-Young Park, Ji Yeon Han, Chi-Hoon Choi, Do-Hyung Kang, Chun Kee Chung, Jun Soo Kwon
2009 Schizophrenia Bulletin  
Although schizophrenia is characterized by gray matter (GM) abnormalities, particularly in the prefrontal and temporal cortices, it is unclear whether cerebral cortical GM is abnormal in individuals at ultra-high-risk (UHR) for psychosis. We addressed this issue by studying cortical thickness in this group with magnetic resonance imaging (MRI). We measured cortical thickness of 29 individuals with no family history of psychosis at UHR, 31 patients with schizophrenia, and 29 healthy matched
more » ... ol subjects using automated surface-based analysis of structural MRI data. Hemispheric mean and regional cortical thickness were significantly different according to the stage of the disease. Significant cortical differences across these 3 groups were found in the distributed area of cerebral cortices. UHR group showed significant cortical thinning in the prefrontal cortex, anterior cingulate cortex, inferior parietal cortex, parahippocampal cortex, and superior temporal gyrus compared with healthy control subjects. Significant cortical thinning in schizophrenia group relative to UHR group was found in all the regions described above in addition with posterior cingulate cortex, insular cortex, and precentral cortex. These changes were more pronounced in the schizophrenia group compared with the control subjects. These findings suggest that UHR is associated with cortical thinning in regions that correspond to the structural abnormalities found in schizophrenia. These structural abnormalities might reflect functional decline at the prodromal stage of schizophrenia, and there may be progressive thinning of GM cortex over time.
doi:10.1093/schbul/sbp151 pmid:20026559 pmcid:PMC3122277 fatcat:luwdm3ex3jem3jqvu7kvssi534

Recurrent Coccidioidomycosis Manifesting as Osteomyelitis in Korea

Ji-hyeon Baek, Eun Young Park, Yoon Suk Jung, Jae Won Hong, Yuntae Chae, Sung Joon Jin, Hee Kyoung Choi, So Youn Shin, Sang Hoon Han, Bum Sik Chin, Chang Oh Kim, Jun Young Choi (+3 others)
2009 Infection & Chemotherapy  
Coccidioidomycosis is a fungal infection that results from inhaling the airborne arthroconidia of the Coccidioides species. It is an endemic disease in the southwest part of North America and rarely diagnosed in Korea. As tourism to endemic areas and the number of immunocompromised patients have been increasing, the incidence of this infection has increased in non-endemic areas. Treatment is usually successful with antifungal agents; however, recurrence is common. It is difficult to decide when
more » ... to discontinue the antifungal treatment especially in non-endemic areas where doctors are not familiar with the disease. We report a case of recurrent coccidioidomycosis manifesting as osteomyelitis after the treatment of the patient for disseminated coccidioidal infection. The complement fixation test was a useful tool for the assessment of patient response and to evaluate suspected recurrence.
doi:10.3947/ic.2009.41.4.253 fatcat:ppy5z5qfa5gbnj5f2y2h7kuphy

Nodular opacities in pulmonary paragonimiasis:Radiologic-pathologic correlation

Sang Hoon Lee, Young Min Han, Su Hyun Heong, Myung Jae Kang, Gyung Ho Chung, Myung Hee Sohn, Chong Soo Kim, Ki Chul Choi
1993 Journal of the Korean Radiological Society  
The CT findings of pulmonarγ paragonimiasis are well known. However, the pathologic findings of nodular opacity have not been studied sufficiently. To clarify the nature of nodular opacity on CT in patient with paragominiasis, we reviewed CT scans of 9 patients retrospectively. Five of them were compared with pathologic findings of the resected specimen. Other four patients were confirmed by needle aspiration biopsy. CT scans showed nodular opacities of 5 to 30mm in diameter which were
more » ... ed with perinod비 ar air-space consolidations in all patients. The usual location of nodular opacities were peripheral zone of the lung. Correlation with pathologic findings demonstrated That the nodular opacity on CT scans corresponded to the parasitic granuloma with central ova and intracystic worm. The most frequent CT finding of pulmonaπ paragonimiasis was nodular opacities with perinodular airspace consolidations caused by parasitic granuloma or intracystic worrn. Index Words: Lung, CT 60.1211 Lung, Paragonimiasis 60.2085 서 론 폐 흡 충 증 은 주 로 Paragonimus 1νesterηwψ 에 의 해 발생하는 기생충 질환으로, 제 2 중간숙주인 민물게나 가 재를 날것으로 먹거나 불충분하게 요리하여 먹음으로써 발생하게 되는데, 흉부 방사선검사상 폐결핵과 유사한 소 견을 보여 많은 예에서 폐결핵으로 오인되기도 하며, 결 절양 종괴를 형성할 경우 악성종괴와의 감별 이 문제 되기 도 한다 ( 1 -15) . 폐흡충증은 단순흉부사진이나 전산화단 층촬영소견상, 경계가 불분명한 폐포성 경결 ( air space consolidation) , 낭성 공동, 누루 (burrow tract) , 결절 ( nodule) , 늑막삼출등이 비교적 특징적인 소견으로 *전북대학교 의과대학 병리학교실 보 고 되 었 고 ( 6-18) , 특 히 임 등 ( 16-17)은 충 낭 (worm cyst) 과 누루의 형태학적 특성에 관하여 보고하였다. Yang ( 8) 등은 폐흡충증의 중요한 특정으로써 단순흉부사 진상 결절음영을 강조하였다. 그러나 CT 에서 관찰되는 결 절음영의 병리학적 소견에 관한 보고는 없다. 이에 저 자들은 최근 5년동안 폐흡충증으로 진단받은 환자중 전북 대학교병원에서 전산화단층촬영 (CT) 과 조직검사가 가능 했던 9명을 대상으로 CT소견을 병리적 소견과 연관 분 석하였다. 대상 및 방법 폐흡충증이 의심되어 전산화단층촬영을 시행하였던 환
doi:10.3348/jkrs.1993.29.6.1194 fatcat:aj35hb2iprfg3miqviy7srfwey
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