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Micheline Cambron, Myriam Côté et Alex Gagnon, dir., Les journaux québécois d'une guerre à l'autre. Deux états de la vie culturelle québécoise au XXe siècle,
2019
Papers of the Bibliographical Society of Canada. Cahiers de la Societe bibliographique du Canada. Bibliographical Society of Canada
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L'histoire de la presse de cette période très riche méritait qu'on s'y attarde, et c'est à ce projet que se sont attablés Micheline Cambron, Myriam Côté et Alex Gagnon. ...
Cambron, Gagnon et Côté précisent que ce livre analysera le journal comme un agent de configuration de la vie culturelle, cette dernière étant disséminée dans tout le journal. ...
L'histoire de la presse de cette période très riche méritait qu'on s'y attarde, et c'est à ce projet que se sont attablés Micheline Cambron, Myriam Côté et Alex Gagnon. ...
doi:10.33137/pbsc.v56i1/2.30777
fatcat:xt63vztkyngwjofuibqjfgn6wm
Floods in Provence-Alpes-Côte d'Azur and lessons for French flood risk governance
2021
Natural Hazards
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The Architectural Association of Côte d'Azur (Syndicat des architectes de la Côte d'Azur) suggested a new way of reducing flood risk, starting by adopting a BBB approach that strictly avoids the areas ...
The October 2015 Côte d'Azur disaster According to the official post-event report of the Préfet (regional authority) des Alpes-Maritimes (2016), on Saturday, October 3, 2015, between 20:00 and 21:45, an ...
doi:10.1007/s11069-021-04905-4
fatcat:wvqebnhmtncxvl7ckcfg222xqy
Les alternatives à la détention des mineurs en conflit avec la loi en Côte d'Ivoire
2017
Revue de l'Université de Moncton
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LES ALTERNATIVES À LA DÉTENTION DES MINEURS EN CONFLIT AVEC LA LOI EN CÔTE D'IVOIRE Patricia Myriam Isimat-Mirin Conseillère spéciale du Médiateur de la République de Côte d'IvoireCheffe du service de ...
années 2000 a permis de relancer la réflexion sur les mesures alternatives à la détention des mineurs bien que de gros efforts restent nécessaires comme le souligne la présente note sur la situation en Côte ...
doi:10.7202/1043662ar
fatcat:7uw6rxukrjgtnpexcu6hxmhuri
Transactions manquantes et mesure du risque des titres cotés sur le marché boursier tunisien
2008
Revue Libanaise de Gestion et d Économie
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Transactions manquantes et mesure du risque des titres cotés sur le marché boursier tunisien Abdelkader BOUDRIGA 1 et Myriam TRABELSI -EL GHARBI 2 Résumé Plusieurs titres cotés sur la Bourse des Valeurs ...
En effet, dans le cas où certains titres ne sont pas cotés tous les jours, les rendements de l'indice de marché sont autocorrélés. ...
Myriam TRABELSI
Revue Libanaise de Gestion et d'Economie | Vol. 1, 2008
6
traités sur le nombre total de titres cotés pour une séance de cotation donnée (coupe
transversale). ...
doi:10.1016/s1999-7620(08)70002-8
fatcat:vcmittbginaydpterqk7asca2u
Mycophagy of White-Tailed Deer (Odocoileus virginianus Zimmermann) in the Boreal Forest
2021
Forests
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Mushrooms are a little known source of food for large herbivores, but are of high quality because of their high protein content and digestibility. Approximately 50 epigeous and hypogeous mushroom and lichen species have been identified in the diet of cervids so far using macro remains. Our main objective was to determine which mushroom species are consumed by white-tailed deer (Odocoileus virginianus Zimmermann) using a molecular approach. We collected 114 fecal samples from deer harvested in
doi:10.3390/f12091247
fatcat:s4yn4d7nizcqvnk25a4e6x5zka
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... 14 and 2015 on Anticosti Island (Québec, Canada), extracted total DNA from feces, and amplified fungal DNA specifically via polymerase chain reaction. Amplified fungi DNA was then sequenced with the Illumina method to identify mushroom species consumed by deer. Our results revealed that deer harvested consumed up to 4979 fungal species, including 580 species that appeared to be consumed directly. Adults tended to consume a higher mushroom diversity than juveniles, and mushroom diversity consumed by deer was much higher in 2015 than 2014. Adult females consumed a higher mushroom diversity than males, especially lactating females. Our results contribute to the understanding of the role of mushrooms and their large diversity in white-tailed deer diet.
Extraction of text areas in printed document images
2001
Proceedings of the 2001 ACM Symposium on Document engineering - DocEng '01
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In this paper, we present a document analysis system which is expected to extract regions of interest in greyscale document images. Collected areas are then clustered in text zones and non-text areas using geometric and texture features. The system works in two steps. Regions of interest are retrieved via cumulative gradient considerations. In classification module, we introduced some entropic heuristics. Experiments are done on the MediaTeam Document Database to show the relevance of this criteria.
doi:10.1145/502187.502211
dblp:conf/doceng/DuongCES01
fatcat:u5honiaoxne3hcgh3gnjy34nim
Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome
2016
Molecular and Cellular Biology
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Côté, and J. Smith, unpublished data). ...
doi:10.1128/mcb.00112-16
pmid:27550811
pmcid:PMC5086519
fatcat:l273n7mn55b7te5stkhnspdlia
Mind-body practices for people living with HIV: a systematic scoping review
2019
BMC Complementary and Alternative Medicine
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Mind-body practices are frequently used by people living with HIV to reduce symptoms and improve wellbeing. These include Tai Chi, Qigong, yoga, meditation, and all types of relaxation. Although there is substantial research on the efficacy of mind-body practices in people living with HIV, there is no summary of the available evidence on these practices. The aim of this scoping review is to map available evidence of mind-body practices in people living with HIV. (Int J Soc Res Methodol 8:19-32,
doi:10.1186/s12906-019-2502-z
fatcat:oipp6tmbj5do3pwzarlgzjaj5y
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... 2005) methodological framework was used. A search of 16 peer-review and grey literature databases, websites, and relevant journals was conducted. To identify relevant studies, two reviewers independently applied the inclusion criteria to all abstracts or full articles. Inclusion criteria were: participants were people living with HIV; the intervention was any mind-body practice; and the study design was any research study evaluating one or several of these practices. Data extraction and risk of bias assessment were performed by one reviewer and checked by a second, as needed, using the criteria that Cochrane Collaboration recommends for systematic reviews of interventions (Higgins and Green, Cochrane handbook for systematic reviews of intervention. 2011). A tabular and narrative synthesis was carried out for each mind-body practice. Methods: The Arksey and O'Malley Results: One hundred thirty-six documents drawing on 84 studies met the inclusion criteria. The most widely studied mind-body practice was a combination of least three relaxation techniques (n = 20), followed in declining order by meditation (n = 17), progressive muscle relaxation (n = 10), yoga (n = 9) and hypnosis (n = 8). Slightly over half (47/84) of studies used a RCT design. The interventions were mainly (46/84) conducted in groups and most (51/84) included daily individual home practice. All but two studies were unblinded to participants. Conclusion: The amount of available research on mind-body practices varies by practice. Almost half of the studies in this review were at high risk of bias. However, mindfulness, a combination of least three relaxation techniques and cognitive behavioral strategies, and yoga show encouraging results in decreasing physical and psychological symptoms and improving quality of life and health in people living with HIV. More rigorous studies are necessary to confirm the results of Tai Chi, Qigong, and some relaxation techniques.
Deep Learners Benefit More from Out-of-Distribution Examples
2011
Journal of machine learning research
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Recent theoretical and empirical work in statistical machine learning has demonstrated the potential of learning algorithms for deep architectures, i.e., function classes obtained by composing multiple levels of representation. The hypothesis evaluated here is that intermediate levels of representation, because they can be shared across tasks and examples from different but related distributions, can yield even more benefits. Comparative experiments were performed on a large-scale handwritten
dblp:journals/jmlr/BengioBBBBCCCEEGMLPRSS11
fatcat:3pzqzwsx5zeixhelk53tyaabue
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... aracter recognition setting with 62 classes (upper case, lower case, digits), using both a multi-task setting and perturbed examples in order to obtain out-ofdistribution examples. The results agree with the hypothesis, and show that a deep learner did beat previously published results and reached human-level performance.
Deep Self-Taught Learning for Handwritten Character Recognition
[article]
2010
arXiv
pre-print
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Recent theoretical and empirical work in statistical machine learning has demonstrated the importance of learning algorithms for deep architectures, i.e., function classes obtained by composing multiple non-linear transformations. Self-taught learning (exploiting unlabeled examples or examples from other distributions) has already been applied to deep learners, but mostly to show the advantage of unlabeled examples. Here we explore the advantage brought by out-of-distribution examples. For this
arXiv:1009.3589v1
fatcat:i7yz2qkigbcbhekj2f2345y3om
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... purpose we developed a powerful generator of stochastic variations and noise processes for character images, including not only affine transformations but also slant, local elastic deformations, changes in thickness, background images, grey level changes, contrast, occlusion, and various types of noise. The out-of-distribution examples are obtained from these highly distorted images or by including examples of object classes different from those in the target test set. We show that deep learners benefit more from out-of-distribution examples than a corresponding shallow learner, at least in the area of handwritten character recognition. In fact, we show that they beat previously published results and reach human-level performance on both handwritten digit classification and 62-class handwritten character recognition.
NuA4-dependent Acetylation of Nucleosomal Histones H4 and H2A Directly Stimulates Incorporation of H2A.Z by the SWR1 Complex
2010
Journal of Biological Chemistry
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Structural and functional analyses of nucleosomes containing histone variant H2A.Z have drawn a lot of interest over the past few years. Important work in budding yeast has shown that H2A.Z (Htz1)-containing nucleosomes are specifically located on the promoter regions of genes, creating a specific chromatin structure that is poised for disassembly during transcription activation. The SWR1 complex is responsible for incorporation of Htz1 into nucleosomes through ATP-dependent exchange of
doi:10.1074/jbc.m110.117069
pmid:20332092
pmcid:PMC2871465
fatcat:ggbezfojnvfbdg3x2kqjr54pqe
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... l H2A-H2B dimers for Htz1-H2B dimers. Interestingly, the yeast SWR1 complex is functionally linked to the NuA4 acetyltransferase complex in vivo. NuA4 and SWR1 are physically associated in higher eukaryotes as they are homologous to the TIP60/p400 complex, which encompasses both histone acetyltransferase (Tip60) and histone exchange (p400/Domino) activities. Here we present work investigating the impact of NuA4-dependent acetylation on SWR1-driven incorporation of H2A.Z into chromatin. Using in vitro histone exchange assays with native chromatin, we demonstrate that prior chromatin acetylation by NuA4 greatly stimulates the exchange of H2A for H2A.Z. Interestingly, we find that acetylation of H2A or H4 N-terminal tails by NuA4 can independently stimulate SWR1 activity. Accordingly, we demonstrate that mutations of H4 or H2A N-terminal lysine residues have similar effects on H2A.Z incorporation in vivo, and cells carrying mutations in both tails are nonviable. Finally, depletion experiments indicate that the bromodomain-containing protein Bdf1 is important for NuA4-dependent stimulation of SWR1. These results provide important mechanistic insight into the functional cross-talk between chromatin acetylation and ATP-dependent exchange of histone H2A variants. 4 The abbreviations used are: SWI/SNF, mating type switching/sucrose nonfermenting; HAT, histone acetyltransferase; NuA4, nucleosome acetyltransferase of H4; Htz1, histone H2A.Z-1; TIP60, Tat-interacting protein 60 kDa; SRCAP, Snf2-related CBP activator protein; Esa1, essential Sas2-related acetyltransferase-1; Eaf, Esa1-associated factor; Swc, SWR complex; Bdf1, bromodomain factor-1; TAP, tandem affinity-purified. Downloaded from FIGURE 6. Histone H4 and H2A acetylation-defective mutants show decreased incorporation of H2A.Z at specific chromosomal loci in vivo, and their combination is lethal for the cell. H2A.Z (Htz1) enrichment at the promoters of SGF29 (Ϫ273 to Ϫ60 bp from transcription start site) (A), ABP1 (Ϫ310 to Ϫ29) (B), 10 kb from TelVIR (C), and 12 kb from TelVL (D) was analyzed by chromatin immunoprecipitations. Putative variation in nucleosome occupancy was corrected by analyzing in parallel total histone H3 signals at the same locations. H2A.Z enrichment was measured as a ratio of Htz1 to H3 immunoprecipitation/input (values range from 0.2 to 0.3 Htz1/H3 ratio in wild type cells). Data are presented as a relative change compared with isogenic wild type strain (set to 1). Standard errors are based on two to four independent experiments. E, a yeast strain with all core histone genes deleted and covered by a URA3 vector containing a single copy of H4, H3, H2A, and H2B genes was transformed with a Leu2 vector expressing wild type histones or histones mutated on the lysine residues targeted by the NuA4 complex in vivo (H4 Lys-5/8/12 and H2A Lys-3/7/13) to arginines or glutamines. Exponentially growing cells were then serially diluted (10-fold) and spotted on control plates lacking leucine and uracil or on 5-fluoro-orotic acid (5ЈFOA) plates to get rid of the URA3 expressing vector.
Comparative impact of two continuing education activities targeted at COPD educators on educational outcomes: protocol for a non-randomized controlled study using mixed methods
2018
BMC Health Services Research
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Therapeutic patient education (TPE) improves quality of life and reduces health care utilization among patients with chronic obstructive pulmonary disease (COPD). However, benefits from TPE might depend on the performance of the educators and training is needed to ensure the effective delivery of TPE interventions. Based on the framework by Moore et al. (J Contin Educ Health Prof 29:1-15, 2009), we will compare the impact of two continuing education (CE) activities on TPE in regard to the
doi:10.1186/s12913-018-3284-6
pmid:29914484
pmcid:PMC6006567
fatcat:x5qx6m7sr5ertbm45ynf3bbl6q
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... ing educational outcomes: (1) learning, (2) self-report of competence, (3) performance of the educators, and (4) outcomes of COPD patients who will meet the newly trained educators for TPE. Methods: We will conduct a non-randomized controlled study using mixed methods. Educators will first participate in a CE activity on TPE that will include a role-playing simulation (experimental group) or in a lecture on TPE (comparison group) and then will perform TPE in COPD patients. Among educators, we will assess: (1) learning, by measuring knowledge about TPE, and (2) self-report of competence using self-administered questionnaires before and after the activity. Then, after the CE activity, we will assess (3) educators' performance levels in delivering TPE by rating a videotaped TPE intervention. In COPD patients who will meet the newly trained educators for TPE after either CE activity, we will assess (4) quality of life and resource utilization using interviewer-administered questionnaires, before and after TPE. Statistical analyses will compare the experimental group against the comparison group using multivariate models. Using a semi-structured interview guide, we will conduct interviews with educators and perform content analysis. Results will be integrated in order that qualitative results further explain the quantitative ones. Discussion: To the best of our knowledge, this is the first controlled mixed methods study to compare the impact of two CE activities on TPE in regard to four educational outcomes. We believe this study will serve as a model for evaluating CE activities on TPE. Results from this study could increase educators' performance levels in delivering effective TPE interventions, and, in turn, COPD patient outcomes.
The minimal clinically important difference determined using item response theory models: an attempt to solve the issue of the association with baseline score
2014
Journal of Clinical Epidemiology
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Objectives: Determining the minimal clinically important difference (MCID) of questionnaires on an interval scale, the trait level (TL) scale, using item response theory (IRT) models could overcome its association with baseline severity. The aim of this study was to compare the sensitivity (Se), specificity (Sp), and predictive values (PVs) of the MCID determined on the score scale (MCID-Sc) or the TL scale (MCID-TL). Study Design and Setting: The MCID-Sc and MCID-TL of the MOS-SF36 general
doi:10.1016/j.jclinepi.2013.10.009
pmid:24447591
fatcat:dut7ipsjmbdxjg4lrcpjjjswza
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... th subscale were determined for deterioration and improvement on a cohort of 1,170 patients using an anchor-based method and a partial credit model. The Se, Sp, and PV were calculated using the global rating of change (the anchor) as the gold standard test. Results: The MCID-Sc magnitude was smaller for improvement (1.58 points) than for deterioration (À7.91 points). The Se, Sp, and PV were similar for MCID-Sc and MCID-TL in both cases. However, if the MCID was defined on the score scale as a function of a range of baseline scores, its Se, Sp, and PV were consistently higher. Conclusion: This study reinforces the recommendations concerning the use of an MCID-Sc defined as a function of a range of baseline scores. Ó
Structure and nucleosome interaction of the yeast NuA4 and Piccolo–NuA4 histone acetyltransferase complexes
2011
Nature Structural & Molecular Biology
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We have used electron microscopy (EM) and biochemistry to characterize the structure and nucleosome core particle (NCP) interaction of NuA4, an essential yeast histone acetyltransferase (HAT) complex conserved throughout eukaryotes. The ATM-related Tra1 subunit, shared with the SAGA coactivator, forms a large domain joined to a second portion that accommodates the Piccolo catalytic subcomplex and other NuA4 subunits. EM analysis of an NuA4-NCP complex shows the NCP bound at NuA4's periphery. EM
doi:10.1038/nsmb.2128
pmid:21984211
pmcid:PMC3210417
fatcat:ixlcfvamujb4bekqoa7ykf5s2q
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... characterization of Piccolo and Piccolo-NCP provided further information about subunit organization and confirmed that histone acetylation requires minimal contact with the NCP. A small conserved region at the N-terminus of Piccolo subunit Epl1 is essential for NCP interaction, whereas subunit Yng2 apparently positions Piccolo Users may view, print, copy, download and text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms Correspondence should be addressed to F.J.A. (asturias@scripps.edu) or J.C. (jacques.cote@crhdq.ulaval.ca). Author Contributions: M.J.C. and J.M.-S. expressed and purified NuA4 for EM analysis. J.M-S. expressed and purified the SAGA complex; J.M-S., R.T.U., V.S., M.C., and S.A. expressed and purified NuA4 and recombinant component subunits for biochemical analysis and performed all biochemical analyses of NuA4 and component subunits; W.S. produced recombinant NCP; W.S. and J.H.
Soins plus — mise en place d'une intervention à trois volets visant à accroître la visibilité et la disponibilité du pharmacien dans un hôpital pédiatrique : une étude randomisée contrôlée
2021
The Canadian Journal of Hospital Pharmacy
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Adresse de correspondance: Marie-Élaine Métras CHU Sainte-Justine 3175, chemin de la Côte-Sainte-Catherine Montréal QC H3T 1C5 Courriel : marie-elaine.metras.hsj@ssss.gouv.qc.ca Financement : Les frais ...
doi:10.4212/cjhp.v74i2.3107
fatcat:uempjq25arecrnyp5sstordati
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