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In vivo kinetics of [F-18]MEFWAY: A comparison with [C-11]WAY100635 and [F-18]MPPF in the nonhuman primate

D.W. Wooten, J.D. Moraino, A.T. Hillmer, J.W. Engle, O.J. DeJesus, D. Murali, T.E. Barnhart, R.J. Nickles, R.J. Davidson, M.L. Schneider, J. Mukherjee, B.T. Christian
2010 Synapse  
F-18] Mefway was developed to provide an F-18 labeled positron emission tomography (PET) neuroligand with high affinity for the serotonin 5-HT 1A receptor to improve the in vivo assessment of the 5-HT  ...  The in vivo kinetics of the radiotracers were compared based on the nondisplaceable distribution volume (V ND ) and binding potential (BP ND ).  ...  Alex Converse and Nick Vandehey for technical discussions. Dr. Suresh Pandey and Neil Saigal for assistance with the radiochemical synthesis of mefway.  ... 
doi:10.1002/syn.20878 pmid:21484878 pmcid:PMC3080024 fatcat:43sa3whgkbbnpan2p7y53gitly