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Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling
2014
NeuroImage
Preserved Fulltext
The ENIGMA-DTI consortium is developing and evaluating approaches for obtaining pooled estimates of heritability through meta-and mega-genetic analytical approaches, to estimate the general additive genetic ...
This is especially important for genetic studies where a large number of observations are required to obtain sufficient power to detect and replicate genetic effects. ...
Data collection for the Bipolar Family Study was supported by an Academy of Medical Sciences/Health Foundation Clinician Scientist Fellowship to AMM. ...
doi:10.1016/j.neuroimage.2014.03.033
pmid:24657781
pmcid:PMC4043878
fatcat:mxe7lkp2hfdyrdmcgzzhdbh3zm
The comprehensive genetic architecture of brain white matter
[article]
2020
bioRxiv
pre-print
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In summary, this large-scale tract-specific study provides a big step forward in understanding the genetics of white matter and its genetic links to other complex traits. ...
Although under strong genetic control, a large number of genetic variants of white matter remain undiscovered. ...
Multi-site study of additive genetic effects on fractional 4 anisotropy of cerebral white matter: comparing meta and megaanalytical 5 approaches for data pooling. Neuroimage 95, 136-150 (2014). 6 40. ...
doi:10.1101/2020.05.23.112409
fatcat:fc5dp3rjivcspdppaqkcwov5p4
Peak width of skeletonized mean diffusivity (PSMD) as marker of widespread white matter tissue damage in multiple sclerosis
2019
Multiple Sclerosis and Related Disorders
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Here, we gathered and meta-analyzed 43 cross-sectional diffusion tensor imaging (DTI) data from 10 population-based cohort studies 44 in order to establish the time course of white matter water diffusion ...
37 Parameters of water diffusion in white matter derived from diffusion-weighted imaging (DWI), 38 such as fractional anisotropy (FA), mean, axial, and radial diffusivity (MD, AD and RD), and 39 more recently ...
Multi-site study of additive genetic effects on 502 fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical 503 doi:10.1016/j.neuroimage.2014.03.033 505 36.Chad JA, Pasternak ...
doi:10.1016/j.msard.2018.11.011
fatcat:7dnedeu5xnezvc2byiipp3jiem
An overview of the first 5 years of the ENIGMA obsessive–compulsive disorder working group: The power of worldwide collaboration
2020
Human Brain Mapping
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multi-site analyses, as well as access to a collaborative community of neuroimaging scientists. ...
We conclude with a summary of ongoing work by ENIGMA-OCD, and a consideration of future directions for neuroimaging research on OCD within and beyond ENIGMA. ...
Moreover, we expect that multimodal imaging approaches, combining data on morphological features with measurements of white matter integrity and information on network function using resting-state fMRI ...
doi:10.1002/hbm.24972
pmid:32154629
pmcid:PMC8675414
fatcat:utcosnl3xvb3tdwww54wm7ogiq
Retrospective harmonization of multi-site diffusion MRI data acquired with different acquisition parameters
[article]
2018
bioRxiv
pre-print
Preserved Fulltext
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A joint and integrated analysis of multi-site diffusion MRI (dMRI) datasets can dramatically increase the statistical power of neuroimaging studies and enable comparative studies pertaining to several ...
such as b-value, spatial resolution and number of gradient directions in the dMRI data (typical for multi-site clinical research scans). ...
Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling. NeuroImage 95, 565 136 -150. ...
doi:10.1101/314179
fatcat:unxcgsgulvcmfdm4g75idp4zpa
An overview of the first 5 years of the ENIGMA obsessive-compulsive disorder working group: the power of worldwide collaboration
2020
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
multi-site analyses, as well as access to a collaborative community of neuroimaging scientists. ...
We conclude with a summary of ongoing work by ENIGMA-OCD, and a consideration of future directions for neuroimaging research on OCD within and beyond ENIGMA. ...
Moreover, we expect that multimodal imaging approaches, combining data on morphological features with measurements of white matter integrity and information on network function using resting-state fMRI ...
doi:10.5167/uzh-186589
fatcat:kisiw2iabfckfn6emipyyt5pyu