Filters








6 Hits in 3.8 sec

Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling

Peter Kochunov, Neda Jahanshad, Emma Sprooten, Thomas E. Nichols, René C. Mandl, Laura Almasy, Tom Booth, Rachel M. Brouwer, Joanne E. Curran, Greig I. de Zubicaray, Rali Dimitrova, Ravi Duggirala (+29 others)
2014 NeuroImage  
The ENIGMA-DTI consortium is developing and evaluating approaches for obtaining pooled estimates of heritability through meta-and mega-genetic analytical approaches, to estimate the general additive genetic  ...  This is especially important for genetic studies where a large number of observations are required to obtain sufficient power to detect and replicate genetic effects.  ...  Data collection for the Bipolar Family Study was supported by an Academy of Medical Sciences/Health Foundation Clinician Scientist Fellowship to AMM.  ... 
doi:10.1016/j.neuroimage.2014.03.033 pmid:24657781 pmcid:PMC4043878 fatcat:mxe7lkp2hfdyrdmcgzzhdbh3zm

The comprehensive genetic architecture of brain white matter [article]

Bingxin Zhao, Tengfei Li, Yue Yang, Xifeng Wang, Tianyou Luo, Yue Shan, Ziliang Zhu, Di Xiong, Yun Li, Jason L Stein, Hongtu Zhu
2020 bioRxiv   pre-print
In summary, this large-scale tract-specific study provides a big step forward in understanding the genetics of white matter and its genetic links to other complex traits.  ...  Although under strong genetic control, a large number of genetic variants of white matter remain undiscovered.  ...  Multi-site study of additive genetic effects on fractional 4 anisotropy of cerebral white matter: comparing meta and megaanalytical 5 approaches for data pooling. Neuroimage 95, 136-150 (2014). 6 40.  ... 
doi:10.1101/2020.05.23.112409 fatcat:fc5dp3rjivcspdppaqkcwov5p4

Peak width of skeletonized mean diffusivity (PSMD) as marker of widespread white matter tissue damage in multiple sclerosis

C. Vinciguerra, A. Giorgio, J. Zhang, I. Di Donato, M.L. Stromillo, R. Tappa Brocci, A. Federico, M.T. Dotti, N. De Stefano
2019 Multiple Sclerosis and Related Disorders  
Here, we gathered and meta-analyzed 43 cross-sectional diffusion tensor imaging (DTI) data from 10 population-based cohort studies 44 in order to establish the time course of white matter water diffusion  ...  37 Parameters of water diffusion in white matter derived from diffusion-weighted imaging (DWI), 38 such as fractional anisotropy (FA), mean, axial, and radial diffusivity (MD, AD and RD), and 39 more recently  ...  Multi-site study of additive genetic effects on 502 fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical 503 doi:10.1016/j.neuroimage.2014.03.033 505 36.Chad JA, Pasternak  ... 
doi:10.1016/j.msard.2018.11.011 fatcat:7dnedeu5xnezvc2byiipp3jiem

An overview of the first 5 years of the ENIGMA obsessive–compulsive disorder working group: The power of worldwide collaboration

Odile A. Heuvel, Premika S.W. Boedhoe, Sara Bertolin, Willem B. Bruin, Clyde Francks, Iliyan Ivanov, Neda Jahanshad, Xiang‐Zhen Kong, Jun S. Kwon, Joseph O'Neill, Tomas Paus, Yash Patel (+51 others)
2020 Human Brain Mapping  
multi-site analyses, as well as access to a collaborative community of neuroimaging scientists.  ...  We conclude with a summary of ongoing work by ENIGMA-OCD, and a consideration of future directions for neuroimaging research on OCD within and beyond ENIGMA.  ...  Moreover, we expect that multimodal imaging approaches, combining data on morphological features with measurements of white matter integrity and information on network function using resting-state fMRI  ... 
doi:10.1002/hbm.24972 pmid:32154629 pmcid:PMC8675414 fatcat:utcosnl3xvb3tdwww54wm7ogiq

Retrospective harmonization of multi-site diffusion MRI data acquired with different acquisition parameters [article]

Suheyla Cetin Karayumak, Sylvain Bouix, Lipeng Ning, Martha Shenton, Marek Kubicki, Yogesh Rathi
2018 bioRxiv   pre-print
A joint and integrated analysis of multi-site diffusion MRI (dMRI) datasets can dramatically increase the statistical power of neuroimaging studies and enable comparative studies pertaining to several  ...  such as b-value, spatial resolution and number of gradient directions in the dMRI data (typical for multi-site clinical research scans).  ...  Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling. NeuroImage 95, 565 136 -150.  ... 
doi:10.1101/314179 fatcat:unxcgsgulvcmfdm4g75idp4zpa

An overview of the first 5 years of the ENIGMA obsessive-compulsive disorder working group: the power of worldwide collaboration

Odile A Van Den Heuvel, Premika S W Boedhoe, Sara Bertolin, Willem B Bruin, Clyde Francks, Iliyan Ivanov, Neda Jahanshad, Xiang-Zhen Kong, Jun S Kwon, Joseph O'Neill, Tomas Paus, Yash Patel (+21 others)
2020
multi-site analyses, as well as access to a collaborative community of neuroimaging scientists.  ...  We conclude with a summary of ongoing work by ENIGMA-OCD, and a consideration of future directions for neuroimaging research on OCD within and beyond ENIGMA.  ...  Moreover, we expect that multimodal imaging approaches, combining data on morphological features with measurements of white matter integrity and information on network function using resting-state fMRI  ... 
doi:10.5167/uzh-186589 fatcat:kisiw2iabfckfn6emipyyt5pyu