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Concepts of Connectivity and Human Epileptic Activity

Louis Lemieux, Jean Daunizeau, Matthew C. Walker
2011 Frontiers in Systems Neuroscience  
We begin by reviewing basic principles of connectivity, followed by a description of connectivity measurement and quantification methodologies.  ...  We are motivated by the following two perceived needs: firstly, to relate the various measures of connectivity found in the field of epilepsy research to the more general language of functional and effective  ...  Besides, stochastic DCM reduces to deterministic DCM by a priori constraining the neural noise variance to 0.  ... 
doi:10.3389/fnsys.2011.00012 pmid:21472027 pmcid:PMC3065658 fatcat:74bxbrc3xjgexmsx3ivw6k2jv4

Of Genes and Patients: Stochastic Dynamic Causal Modelling of the Prefrontal-Hippocampal Network

David Bernal Casas
2013
We strive on giving a plausible biological interpretation to the sDCM parameter estimates by linking the concepts of causal connectivity and functional (E-I) balance.  ...  In this study, we focus on identifying alterations on genetic risk carriers and schizophrenia patients from the prefrontal-hippocampal network estimated with sDCM.  ...  Multi-site reproducibility of prefrontal-hippocampal connectivity estimates by sDCM in healthy volunteers ).  ... 
doi:10.11588/heidok.00015229 fatcat:7hpgzrxhirf23odtrzqodrhygq

26th Annual Computational Neuroscience Meeting (CNS*2017): Part 1

Sue Denham, Panayiota Poirazi, Erik De Schutter, Karl Friston, Ho Ka Chan, Thomas Nowotny, Dongqi Han, Sungho Hong, Sophie Rosay, Tanja Wernle, Alessandro Treves, Sarah Goethals (+90 others)
2017 BMC Neuroscience  
Among neuronal populations, patterns of synchronization can drive connectivity changes, in turn modifying oscillations and synchronization.  ...  Our preliminary results show that with learning the network is reweighted into a new structure with relatively high levels of SW (Fig. 1A) , but a fully connected pattern.  ...  functional connectivity between the sites.  ... 
doi:10.1186/s12868-017-0370-3 fatcat:qq2cmqlotbg7vpqlqmmcql4u5i

26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3

Adam J. H. Newton, Alexandra H. Seidenstein, Robert A. McDougal, Alberto Pérez-Cervera, Gemma Huguet, Tere M-Seara, Caroline Haimerl, David Angulo-Garcia, Alessandro Torcini, Rosa Cossart, Arnaud Malvache, Kaoutar Skiker (+526 others)
2017 BMC Neuroscience  
Among neuronal populations, patterns of synchronization can drive connectivity changes, in turn modifying oscillations and synchronization.  ...  Our preliminary results show that with learning the network is reweighted into a new structure with relatively high levels of SW (Fig. 1A) , but a fully connected pattern.  ...  functional connectivity between the sites.  ... 
doi:10.1186/s12868-017-0372-1 fatcat:q5x3vgivujgshmtthc6ki4fcfu

28th Annual Computational Neuroscience Meeting: CNS*2019

2019 BMC Neuroscience  
However, most studies use simplified oscillator paradigms with some bioispiration from the connectivity of living CPGs.  ...  We have recently revealed the presence of dynamical invariants in the pyloric CPG in the form of cycle-by-cycle linear relations among specific time intervals and the instantaneous period [4].  ...  Specifically, delaying the optical stimulation relative to the hippocampal signal by about half of its period enhanced the entrainment of the prefrontal and hippocampal field potential responses to the  ... 
doi:10.1186/s12868-019-0538-0 fatcat:3pt5qvsh45awzbpwhqwbzrg4su

27th Annual Computational Neuroscience Meeting (CNS*2018): Part One

2018 BMC Neuroscience  
Acknowledgements This work has been supported by the Creative Unit I-See of the University of Bremen and the BMBF, Bernstein Award Udo Ernst, Grant No. 01GQ1106.  ...  the neural recordings of locust.  ...  by a dipole, while the macroscopic anatomy of the hippocampal structure was reproduced by positioning and connecting the neurons in an anatomically realistic manner.  ... 
doi:10.1186/s12868-018-0452-x pmid:30373544 pmcid:PMC6205781 fatcat:xv7pgbp76zbdfksl545xof2vzy

EMG-based Simultaneous and Proportional Estimation of Wrist Kinematics and its Application in Intuitive Myoelectric Control for Unilateral transradial Amputees

Farina Dario
2011 Frontiers in Computational Neuroscience  
Although patterns of intra-and inter-layer synaptic connectivity have been identified in PFC, the laminar organization of sensory, motor and memory-related activity within this network remains unknown.  ...  Acknowledgements Center for Neural Science, New York University, USA Prefrontal cortex (PFC) is the hub of a distributed system that coordinates the selection, planning and execution of motor behaviors  ...  We demonstrate the versatility of the coupled Gamma model for estimating functional connectivity from multi-electrode recordings.  ... 
doi:10.3389/conf.fncom.2011.53.00081 fatcat:nkq5wesfpbcjnikbxqh3v3gtqi

25th Annual Computational Neuroscience Meeting: CNS-2016

Tatyana O. Sharpee, Alain Destexhe, Mitsuo Kawato, Vladislav Sekulić, Frances K. Skinner, Daniel K. Wójcik, Chaitanya Chintaluri, Dorottya Cserpán, Zoltán Somogyvári, Jae Kyoung Kim, Zachary P. Kilpatrick, Matthew R. Bennett (+597 others)
2016 BMC Neuroscience  
Part of this complexity is related to the number of different cell types that work together to encode stimuli.  ...  BMC Neuroscience 2016, 17(Suppl 1):A1 Neural circuits are notorious for the complexity of their organization.  ...  Acknowledgements: The work of JB, RG, and SMC was supported in part by R01MH1006674 from the National Institutes of Health.  ... 
doi:10.1186/s12868-016-0283-6 pmid:27534393 pmcid:PMC5001212 fatcat:bt45etzj2bbolfcxlxo7hlv6ju

30th Annual Computational Neuroscience Meeting: CNS*2021–Meeting Abstracts

2021 Journal of Computational Neuroscience  
One of the goals of neuroscience is to understand the computational principles that describe the formation of behaviorally relevant signals in the brain, as well as how these computations are realized  ...  within the constraints of biological networks.  ...  Owing to the randomness of positions of cells and connectivity, there were large variations of the strength of the PC response depending on the precise location of the stimulus.  ... 
doi:10.1007/s10827-021-00801-9 pmid:34931275 pmcid:PMC8687879 fatcat:evpmmfpaivgpxdqpive5xdgmwu

29th Annual Computational Neuroscience Meeting: CNS*2020

2020 BMC Neuroscience  
by visual experience, and (iii) how patterns of neural activity in the zebrafish brain develop to facilitate precisely targeted hunting behaviour.  ...  This includes (i) how growing axons navigate to their targets by detecting and responding to molecular cues in their environment, (ii) the formation of maps in the visual cortex and how these are influenced  ...  Acknowledgements: This research is funded by the National Science Foundation (grants #1822517 and #1921515 to SJ), the National Institute of Mental Health (grant #MH117488 to SJ), the California Nano-Systems  ... 
doi:10.1186/s12868-020-00593-1 pmid:33342424 fatcat:edosycf35zfifm552a2aogis7a

Electrophysiological Brain Connectivity: Theory and Implementation

Bin He, Laura Astolfi, Pedro A. Valdes-Sosa, Daniele Marinazzo, Satu Palva, Christian G. Benar, Christoph M. Michel, Thomas Koenig
2019 IEEE Transactions on Biomedical Engineering  
We review the theory and algorithms of electrophysiological brain connectivity analysis.  ...  Various connectivity estimators are discussed, and algorithms introduced. Important issues for estimating and mapping brain functional connectivity with electrophysiology are discussed.  ...  Connectivity patterns estimated for this task reveal an involvement of right parietal and bilateral premotor and prefrontal cortical areas.  ... 
doi:10.1109/tbme.2019.2913928 pmid:31071012 pmcid:PMC6834897 fatcat:qqxxwzgbkbh37je7ztfjjkpima

ACNP 58th Annual Meeting: Panels, Mini-Panels and Study Groups

2019 Neuropsychopharmacology  
In parallel, two analogues were assayed in brain slices using genetically-encoded optical sensors for dynorphin developed by Lin Tian's lab at UC Davis.  ...  Results: Caged dynorphin variants exhibited up nearly 5,000fold reductions in EC50 at the kappa, mu and delta opioid receptors depending on peptide length and caging site (e.g. at KOR: Dyn-8 = 7 nM, CYD8  ...  In contrast, THC-exposed fetuses showed reduction of hippocampal connectivity to regions of the anterior cingulate cortex, insula, dorsolateral prefrontal cortex, and sensorimotor cortex.  ... 
doi:10.1038/s41386-019-0544-z pmid:31801977 pmcid:PMC6957922 fatcat:hjyvf7fcpbf2fhxit6rlhsvg2y

BNA Festival of Neuroscience 2019

2019 Brain and Neuroscience Advances  
This study aimed to investigate the effect of stress on brain connectivity in an adolescent population using a graph theory approach.  ...  T1-w MRI scans were used to extract grey matter connectivity matrices using a published method (Tijms, Series et al. 2012).  ...  There are strong anatomical connections between the prefrontal cortex and hippocampus, mediated by the fornix, consistent with the view that the prefrontal cortex and hippocampus operate interactively  ... 
doi:10.1177/2398212819855490 fatcat:y4b5r7rpdnblzoxvb2crpzqhee

27th Annual Computational Neuroscience Meeting (CNS*2018): Part Two

2018 BMC Neuroscience  
Acknowledgements Supported by NINDS 1 R01 NS085006 to RLC. Acknowledgments JB was supported by NIH grant F31DC016811 to JB and JB, SC, and RG were supported by NIH R01MH1006674 to SC.  ...  This work is supported by the CMBC Interdisciplinary Neuroscience Pilot Research Fund at Emory University. Acknowledgments This work is supported by NSF grant DMS-1517085.  ...  Stochastic Ca2+ channel gating is a major source of this stochasticity [2] [3] [4] .  ... 
doi:10.1186/s12868-018-0451-y fatcat:afgrjlnjgjarldkuwo3e2pt5sm

2016 Biennial Meeting of the American Society for Stereotactic and Functional Neurosurgery, Chicago, IL, USA, June 18-21, 2016: Abstracts

2016 Stereotactic and Functional Neurosurgery  
The estimated frequency of completed suicide was 1 per every 1100 patient-months of follow-up.  ...  Patients receiving SCC DBS for depression represented the bulk of the LTFU (3658 patient-months or 304.8 patient-years), followed by Anorexia Nervosa (650 patient-months or 54.2 patient-years) and Bipolar  ...  DBS infections may be a largely stochastic occurrence.  ... 
doi:10.1159/000455386 pmid:28092908 fatcat:dfobre7vdfcqvekxhbc4aekwgy
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