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Multi-Scale Modeling of Patient-Specific Ventricular Geometry, Fiber Structure, and Biomechanics

Adarsh Krishnamurthy, Chris Villongco, Roy Kerckhoffs, Andrew McCulloch
2012 Biophysical Journal  
This first in situ mechanical analysis of a living myocardium revealed differences in cardiac mechanics due to age and suggest that aspects of the mechanical properties of the aging phenotype differ between  ...  Passive myocardial properties were optimized using semi-automated methods while simultaneously computing the unloaded reference geometry.  ...  Human myofiber and sheet architecture was estimated using eigenvectors computed from Diffusion Tensor MRI obtained in an isolated, fixed human organ donor heart and mapped to the patient-specific geometric  ... 
doi:10.1016/j.bpj.2011.11.1924 fatcat:6iszvpe7jrglzmnp34wbcqpsyu

Cross-Bridge Cycling Kinetics in Intact Multicellular Cardiac Muscle at Physiological Temperature: Impact of Muscle Length

Nima Milani-Nejad, Ying Xu, Jonathan P. Davis, Paul M.L. Janssen
2012 Biophysical Journal  
This first in situ mechanical analysis of a living myocardium revealed differences in cardiac mechanics due to age and suggest that aspects of the mechanical properties of the aging phenotype differ between  ...  Passive myocardial properties were optimized using semi-automated methods while simultaneously computing the unloaded reference geometry.  ...  Human myofiber and sheet architecture was estimated using eigenvectors computed from Diffusion Tensor MRI obtained in an isolated, fixed human organ donor heart and mapped to the patient-specific geometric  ... 
doi:10.1016/j.bpj.2011.11.1925 fatcat:dwwrehajz5cnllgxmyranzj4ea

In Situ Mechanical Analysis of Genetic Modification and Aging on Soft, Bilayered Drosophila Myocardium

Gaurav Kaushik, Alexander Fuhrmann, Anthony Cammarato, Adam J. Engler
2012 Biophysical Journal  
This first in situ mechanical analysis of a living myocardium revealed differences in cardiac mechanics due to age and suggest that aspects of the mechanical properties of the aging phenotype differ between  ...  Passive myocardial properties were optimized using semi-automated methods while simultaneously computing the unloaded reference geometry.  ...  Human myofiber and sheet architecture was estimated using eigenvectors computed from Diffusion Tensor MRI obtained in an isolated, fixed human organ donor heart and mapped to the patient-specific geometric  ... 
doi:10.1016/j.bpj.2011.11.1922 fatcat:jd2g5mzembaadls352ykaejd3i

Exploration and Suppression of Cardiac Amyloidosis Induced by Huntington's Disease-Causing Amyloid in the Drosophila Heart Model

Girish C. Melkani, Rolf Bodmer, Karen Ocorr, Sanford I. Bernstein
2012 Biophysical Journal  
This first in situ mechanical analysis of a living myocardium revealed differences in cardiac mechanics due to age and suggest that aspects of the mechanical properties of the aging phenotype differ between  ...  Passive myocardial properties were optimized using semi-automated methods while simultaneously computing the unloaded reference geometry.  ...  Human myofiber and sheet architecture was estimated using eigenvectors computed from Diffusion Tensor MRI obtained in an isolated, fixed human organ donor heart and mapped to the patient-specific geometric  ... 
doi:10.1016/j.bpj.2011.11.1923 fatcat:wcm46rudrjfkfeu7kysuuwib5q

Incorporation of terpyridine into the side chain of copolymers to create multi-functional materials

Gregory N. Tew, Khaled A. Aamer, Raja Shunmugam
2005 Polymer  
Polymer architectures containing metal-ligands in their side chain represent a diverse approach to generating multi-functional materials.  ...  The ability to define a versatile synthetic platform will enable many chemistries and architectures to be studied.  ...  Introduction Hybrid materials are formed by integrating organic and inorganic components into the same molecular backbone leading to a wide variety of advanced properties and applications [1] .  ... 
doi:10.1016/j.polymer.2005.04.084 fatcat:blxdpntjkbepjigkfpm2b5dxqq

Applications of Shape Memory Polymers in Kinetic Buildings

Jing Li, Qiuhua Duan, Enhe Zhang, Julian Wang
2018 Advances in Materials Science and Engineering  
The corresponding mechanisms, constitutive models, and properties (i.e., mechanical, electrical, optical, shape, etc.) of the SMPs in response to different stimulus methods are then reviewed.  ...  Shape memory polymers (SMPs) have attracted significant attention from both industrial and academic researchers, due to their useful and fascinating functionality.  ...  Figure 1 : 1 Modular architecture of an SMP. Figure 2 :Figure 3 : 23 One-way and two-way SMPs. Triple-and multi-SMPs.  ... 
doi:10.1155/2018/7453698 fatcat:yyp5wffarna3dp6mq6x2owxwga

Contents: (Adv. Mater. 30/2021)

2021 Advanced Materials  
Microgravity has proved to be an ideal condition to grow crystals.  ...  number 2101777, Raphael Pfattner, Tiago Sotto Mayor, Daniel Ruiz-Molina, Josep Puigmartí-Luis, and co-workers demonstrate how to generate simulated microgravity on Earth to grow 2D porous crystalline molecular  ...  Stimuli-Responsive Materials Multi-stimuli-responsive soft materials introduce a new dimension in the design and control of soft machines, enhancing their use in complex applications.  ... 
doi:10.1002/adma.202170233 fatcat:huaqkuo35ng6fhxem624u57v5a

Get closer to the intrinsic properties of Ni2+salen polymer semiconductors accessed by chain isolation inside silica nanochannels

Kamila Łępicka, Piyush Sindhu Sharma, Pawel Borowicz, Gregory Francius, Alain Walcarius
2022 Journal of Materials Chemistry C  
This separation resulted in enhanced charge transport properties of poly(meso-NiSaldMe-3dMe) molecular wires compared to poly(meso-NiSaldMe-3dMe) continuous film.  ...  TEM charkV. characterization was carried out using a CM20 microscope at an acceleration voltage of 200.  ... 
doi:10.1039/d2tc00976e fatcat:c5jgenznivaf7npcrrz7fbjwei

The influence of printing parameters on multi-material two-photon polymerisation based micro additive manufacturing

Qin Hu, Graham A. Rance, Gustavo F. Trindade, David Pervan, Long Jiang, Aleksandra Foerster, Lyudmila Turyanska, Christopher Tuck, Derek J. Irvine, Richard Hague, Ricky D. Wildman
2021 Additive Manufacturing  
integration of various materials into multi-material structures.  ...  The approaches developed here are successfully used to demonstrate multimaterial 2PP and produce complex 3D architectures incorporating three polymers.  ...  In our work, optimised printing parameters result in mechanical properties of the materials that preserve the integrity of the fabricated structures after each washing cycle.  ... 
doi:10.1016/j.addma.2021.102575 fatcat:in74gwu5fzdlhpxq5kdl2ps4qu

Two-Way and Multiple-Way Shape Memory Polymers for Soft Robotics: An Overview

Giulia Scalet
2020 Actuators  
Particularly, two-way and multiple-way SMPs offer unique opportunities to realize untethered soft robots with programmable morphology and/or properties, repeatable actuation, and advanced multi-functionalities  ...  applied thermo-mechanical history (i.e., the shape memory cycle) with polymer macromolecular architecture.  ...  Recently, in [287] , a new multi-material density-based topology optimization formulation has been used to determine materials' placement in structures undergoing large deformation and realized through  ... 
doi:10.3390/act9010010 fatcat:7rpo2ivsbbgmjblpn3znlvvdpe

Fractal Nanotechnology

G. F. Cerofolini, D. Narducci, P. Amato, E. Romano
2008 Nanoscale Research Letters  
It is shown that this goal may be achieved via a multiplicative variant of the multi-spacer patterning technology, in this way permitting the controlled preparation of fractal surfaces.  ...  The preparation of nanoscopic samples with assigned properties requires therefore an extreme accuracy in the preparation.  ...  [22] , this requires an accurate control of the rheological and diffusion properties in a medium embedded in a domain of complex geometry.  ... 
doi:10.1007/s11671-008-9170-0 fatcat:alsh7y3tifh7tke4tsvlcyjjz4

Modeling non-linear rheology of PLLA: comparison of Giesekus and Rolie-Poly constitutive models

Maja Stępień, Gabriel Y.H. Choong, Davide S.A. De Focatiis, Łukasz Figiel
2020 International Journal of Biobased Plastics  
Therefore, the predictive capability of two polymer models, a classical Giesekus and a physically-based Rolie-Poly, is compared here for extensional and shear rheology data obtained on a poly(L-lactide  ...  Hence, as the Giesekus model generally needs a smaller number of parameters, this class of models is more attractive when considering their use in computationally demanding forming simulations of biobased  ...  features of the polymer (e.g. molecular weight distribution and molecular architecture).  ... 
doi:10.1080/24759651.2020.1808367 fatcat:y3vpwqag3bahflmgcn3zh2ls34

Recent Progress in Advanced Nanobiological Materials for Energy and Environmental Applications

Hyo-Jick Choi, Carlo Montemagno
2013 Materials  
This concept of an artificial organelle originates from the first synthesis of poly(siloxane)-poly(alkyloxazoline) block copolymers three decades ago and the first demonstration of protein activity in  ...  Ongoing research includes replication of complex biological processes, such as an artificial Calvin cycle for application in biofuel and specialty chemical production, and carbon dioxide sequestration.  ...  Prospects When we look into the future, foam architecture could be used as an alternative to conventional cell culture methods.  ... 
doi:10.3390/ma6125821 pmid:28788424 pmcid:PMC5452742 fatcat:6qdspiwse5hynngj2atuqssxei

Multifunctional binder designs for lithium-sulfur batteries

Qi Qi, Xiaohui Lv, Wei Lv, Quan-Hong Yang
2019 Journal of Energy Chemistry  
To date, tremendous effort s have been devoted to improving the properties of binders, in terms of the viscosity, elasticity, stability, toughness and conductivity, by optimizing the composition and structure  ...  cycling, especially those with high sulfur loadings.  ...  Binding ability enhancements by ion cross-linking Because of the large volume change of sulfur during cycling, the mechanical properties to maintain a stable electrode structure and keep an integrated  ... 
doi:10.1016/j.jechem.2019.02.001 fatcat:jwvjeaydgjejff664fqp7ugme4

Repeated self-healing of nano and micro scale cracks in epoxy based composites by tri-axial electrospun fibers including different healing agents

Jamal Seyyed Monfared Zanjani, Burcu Saner Okan, Ilse Letofsky-Papst, Yusuf Menceloglu, Mehmet Yildiz
2015 RSC Advances  
Multi-walled healing fibers with a novel architecture are fabricated through a direct, one-step tri-axial electrospinning process to encapsulate different healing agents inside the fibers with two distinct  ...  Fig. 3b represents poly(glycidyl methacrylate-co-styrene)/PAAm/ DCPD tri-axial bers fabricated using an outer layer solution prepared in EA and with the diameter of around 1 mm.  ...  In the course of obtaining an ideal ber morphology containing DCPD monomer, PS and poly(glycidyl methacrylate-costyrene) polymers were also used as outer layers of tri-axial bers.  ... 
doi:10.1039/c5ra15483a fatcat:qtkk5toovrg4tlgoxfhyvqxusq
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