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The Mouse Tumor Biology Database: A Comprehensive Resource for Mouse Models of Human Cancer

Debra M. Krupke, Dale A. Begley, John P. Sundberg, Joel E. Richardson, Steven B. Neuhauser, Carol J. Bult
2017 Cancer Research  
The Mouse Tumor Biology (MTB) database is an expertly curated, comprehensive compendium of mouse models of human cancer.  ...  Although thousands of scientific articles have been published about mouse models of human cancer, collating information and data for a specific model is hampered by the fact that many authors do not adhere  ...  The Mouse Tumor Biology (MTB) database (http://tumor. informatics.jax.org) is a comprehensive information resource of mouse models of human cancer.  ... 
doi:10.1158/0008-5472.can-17-0584 pmid:29092943 fatcat:nmyh5hdrjzcv3blugvmqwwl6oq

A Survey of Web Resources for Basic Cancer Genetics Research

Carol J. Bult, Debra M. Krupke, Barbara J. Tennent, Janan T. Eppig
1999 Genome Research  
The purpose of this paper is to summarize information resources and databases available on the World Wide Web that are pertinent to cancer genetics research.  ...  To focus the scope of this survey further, we concentrated on five key areas for basic cancer genetics research: (1) animal models; (2) cancer genetics and genomics; (3) pathology; (4) reagents, services  ...  ACKNOWLEDGMENTS We gratefully acknowledge the support of the NCI (contract 97CSX022A to J.T.E.) and the U.S. Army Breast Cancer Research Program (DAMD17-94-J-4016 to B.J.T.).  ... 
doi:10.1101/gr.9.5.397 fatcat:rh33ydqygrad7e42a4fup2lcaq

Mouse Tumor Biology (MTB): a database of mouse models for human cancer

Carol J. Bult, Debra M. Krupke, Dale A. Begley, Joel E. Richardson, Steven B. Neuhauser, John P. Sundberg, Janan T. Eppig
2014 Nucleic Acids Research  
The Mouse Tumor Biology (MTB; http://tumor. informatics.jax.org) database is a unique online compendium of mouse models for human cancer.  ...  for exploring regions of the mouse genome associated with cancer phenotypes and incorporate data and information related to Patient-Derived Xenograft models of human cancers.  ...  ACKNOWLEDGEMENTS We thank Drs Judith Blake and Joel Wagner for helpful comments on earlier versions of this manuscript. FUNDING  ... 
doi:10.1093/nar/gku987 pmid:25332399 pmcid:PMC4384039 fatcat:xr6nc3fcvng5bnlapb2xjg7gh4

Web-based access to mouse models of human cancers: the Mouse Tumor Biology (MTB) Database

C. J. Bult
2001 Nucleic Acids Research  
MTB has been available on the Web since 1998 from the Mouse Genome Informatics web site (http:// www.informatics.jax.org).  ...  The Mouse Tumor Biology (MTB) Database serves as a curated, integrated resource for information about tumor genetics and pathology in genetically defined strains of mice (i.e., inbred, transgenic and targeted  ...  ACKNOWLEDGEMENTS The authors thank Ms Joyce Worcester for her assistance with the preparation of the pathology image data for publication on the Web.  ... 
doi:10.1093/nar/29.1.95 pmid:11125059 pmcid:PMC29782 fatcat:mhzxwog6rvd23bdoslz276pvna

The Mouse Tumor Biology Database (MTB)

D. A. Begley, D. M. Krupke, S. B. Neuhauser, J. E. Richardson, C. J. Bult, J. T. Eppig, J. P. Sundberg
2011 Veterinary pathology  
The Mouse Tumor Biology Database (MTB) is designed to provide an electronic data storage, search, and analysis system for information on mouse models of human cancer.  ...  The MTB is a community resource that provides integrated access to mouse tumor data from different scientific research areas and facilitates integration of molecular, genetic, and pathologic data.  ...  The authors declared that they received no commercial financial support for their research and/or authorship of this article.  ... 
doi:10.1177/0300985810395726 pmid:21282667 pmcid:PMC3130112 fatcat:atytsfvufrhppnq5emiwgjzjgy

Cancer Biology Data Curation at the Mouse Tumor Biology Database (MTB)

Debra Krupke, Janan Eppig, Dale Begley, Steven Neuhauser, Joel Richardson, John Sundberg, Carol Bult
2009 Nature Precedings  
33,732 tumor frequencies 3,594 strains 3,333 pathology images 169 cytogenetic images ABSTRACT Many advances in the field of cancer biology have been made using mouse models of human cancer.  ...  MTB encourages direct submission of mouse tumor data and images from the cancer research community and provides investigators with a web-accessible tool for image submission and annotation.  ...  , the JAX® Mice Web Site, and the Mouse Models of Human Cancers Consortium's Mouse Repository.  ... 
doi:10.1038/npre.2009.3245.1 fatcat:3dif75wrvrhexfauvnjhrfsuwa
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