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Annular Fiber Probe for Interstitial Illumination in Photoacoustic Guidance of Radiofrequency Ablation

Hindrik Kruit, Kalloor Joseph Francis, Elina Rascevska, Srirang Manohar
2021 Sensors  
Our probe shows potential for RFA device guidance and ablation detection, which potentially aids in real-time monitoring.  ...  The AFP is a cannula with 72 optical fibers that allows an RFA device to slide through its lumen, thereby enabling PA imaging for RFA device guidance and ablation monitoring.  ...  , Monte Carlo simulations were performed.  ... 
doi:10.3390/s21134458 pmid:34209996 fatcat:bunqre4ewjfxlgsydbauo6dtf4

A tissue-mimicking prostate phantom for 980 nm laser interstitial thermal therapy

R. Geoghegan, A. Santamaria, A. Priester, L. Zhang, H. Wu, W. Grundfest, L. Marks, S. Natarajan
2019 International Journal of Hyperthermia  
This phantom will provide a platform for the development and characterization of 980 nm laser interstitial thermal therapy (LITT) systems.  ...  The thermal response of the phantom was similar to that observed clinically with maximum thermal probe measurements of 64.2 °C and 66.9 °C respectively.  ...  Acknowledgements Jessica Martinez, Samantha Mikaiel and Fuad Elkhoury assisted with the acquisition of MRI data.  ... 
doi:10.1080/02656736.2019.1660811 pmid:31544549 pmcid:PMC6827870 fatcat:6fgkkfopkff3zb636mgfu36e2e

Optical Fiber Sensors for Biomedical Applications [chapter]

Lee C.L. Chin, William M. Whelan, I. Alex Vitkin
2010 Optical-Thermal Response of Laser-Irradiated Tissue  
Monte Carlo simulations comparing the fluence with and without a sensor have demonstrated that spherical fluence sensors with diameters as small as 0.5-0.8 mm result in minimal perturbation to the true  ...  , performing high power laser ablation.  ... 
doi:10.1007/978-90-481-8831-4_17 fatcat:75jy4ua43rg7rg4lchkiq57bfe

Contactless Thermometry by MRI and MRS:Advanced Methods for Thermotherapy and Biomaterials

Norbert W. Lutz, Monique Bernard
2020 iScience  
To enable accurate temperature measurement without perturbing or even destroying the biological tissue or material to be monitored, contactless thermometry methods are preferred.  ...  Thus, these methods facilitate optimization of clinical and industrial heating and cooling protocols.  ...  Their Monte Carlo simulations as well as phantom and in vivo validations for many different organs aimed at determining, by way of relaxation time MRI, the conditions under which either dual-pathway sequence  ... 
doi:10.1016/j.isci.2020.101561 pmid:32954229 pmcid:PMC7489251 fatcat:e2agclclczcfzmundbd5lw3mxi

A Model for Online Interactive Remote Education for Medical Physics Using the Internet

Milton K Woo, Kwan-Hoong Ng
2003 Journal of Medical Internet Research  
We analyse this behaviour with Monte-Carlo simulation (EGS4) and ionization dosimetry.  ...  The PEREGRINE 3D Monte Carlo dose calculation system predicts dose by implementing a full Monte Carlo simulation of the beam delivery and patient/phantom system.  ...  Blood vessels were simulated using elastic tubing about 3 mm in diameter, filled with 300 mg/cc iodine contrast media.  ... 
doi:10.2196/jmir.5.1.e3 pmid:12746208 pmcid:PMC1550549 fatcat:tsyf45yusza2jiglkq62rgo3qm

SU-FF-I-79: Java-Based Plugin for Tomographic Reconstruction for SPECT Data

M Andrade, M Costa, A Marques da Silva
2006 Medical Physics (Lancaster)  
Method and Materials: We simulated the online positioning of an anthropomorphic chest phantom with 6 noncoplanar reference BBs attached. Planning CT data of the phantom were acquired with a G.E.  ...  Single-axis rotations up to +/-10 o and 3-axis translations up to +/-10 mm were simulated in the planning CT, prior to the generation of reference DTS images.  ...  The results were compared with true activity in each kidney, known by Monte Carlo simulations.  ... 
doi:10.1118/1.2240759 fatcat:5we2nvgwx5hrxcv2ngufce6obq

Optical aspects of a miniature fluorescence microscope for super-sensitive biomedical detection

Yunfeng Nie, Aikio Sanna, Annukka Kokkonen, Teemu Sipola, Uusitalo Sanna, Simonetta Grilli, Heidi Ottevaere
2020 Zenodo  
We present optical design and the principle demonstrator of a miniature fluorescence microscope aiming for super-sensitive detection.  ...  Current commercial fluorescence microscopes are typically sophisticated, bulky and expensive, not suitable for low-volume or clinic routine biomedical detection.  ...  This study demonstrates HD-DOT mapping of differential processing of language and biological motion between adolescents with and without autism, and that HD-DOT measured brain function correlates with  ... 
doi:10.5281/zenodo.3822435 fatcat:3eoome22a5grbmarbrktphfh7a

Photoacoustic Clinical Imaging

Idan Steinberg, David M. Huland, Ophir Vermesh, Hadas E. Frostig, Willemieke S. Tummers, Sanjiv S. Gambhir
2019 Photoacoustics  
Such a technique has an immense potential for clinical translation since it allows high resolution, sufficient imaging depth, with diverse endogenous and exogenous contrast, and is free from ionizing radiation  ...  Here we survey the various clinical and pre-clinical literature and discuss the potential applications and hurdles that still need to be overcome.  ...  Martin Schneider and Dr. Carmel Chan from Stanford University for their assistance finalizing this paper.  ... 
doi:10.1016/j.pacs.2019.05.001 pmid:31293884 pmcid:PMC6595011 fatcat:yecqy2wwefhlvjgt6qus3cu7i4

A design methodology for 2D sparse NDE arrays using an efficient implementation of refracted-ray TFM

Jerzy Dziewierz, Timothy Lardner, Anthony Gachagan
2013 2013 IEEE International Ultrasonics Symposium (IUS)  
One of these technologies takes advantage of the acoustic radiation forces associated with ultrasound standing wave fields to spatially pattern cells within collagen-based hydrogels.  ...  and nutrients.  ...  The authors acknowledge the ANR and DGA for their support under the project Metactif, grant ANR-11-ASTR-015.  ... 
doi:10.1109/ultsym.2013.0035 fatcat:th5znfh7y5bklfdbmhb4u6iq2i

Thursday 4 September 2014

2014 Journal of Medical Radiation Sciences  
Given how effectively medical imaging is employed in diagnosing chronic conditions and monitoring changes with treatment, growth related to aging is appropriate and to be expected.  ...  More successful have we been with technical approaches allowing dose sparing treatments.  ...  Method: Monte Carlo simulated dose profiles of various water equivalent plastic phantoms are compared to a water tank phantom.  ... 
doi:10.1002/jmrs.70 pmid:27759940 pmcid:PMC4263482 fatcat:o23ixn3zgvcenowujmhcq2sx6m

Integrated butt-coupled membrane laser for Indium Phosphide on Silicon platform

V. Pogoretskiy, A. Higuera-Rodriguez, Y. Jiao, J. J. G. M van der Tol, D. Heiss, M. K. Smit
2016 2016 International Conference Laser Optics (LO)  
Petersburg State Univ., Russia, 3 -Drexel Univ., United States The Monte Carlo simulations of the photon migration in tissue models are performed for the time and frequency domains.  ...  P E T E R S BU RG, R U S S Monte Carlo simulations of photon diffusion in time and frequency domains V.L. Kuzmin 1 , A.Yu. Valkov 1,2 , A.D. Oskirko 1,2 , L.A. Zubkov 3 ; 1 -Peter the Great St.  ...  Within this contribution, we present spectroelectrochemistry using a BDD-modified IR-ATR crystal in with atomic force microscopy. WePD-07 Gorodetsky M.L. ThR8-41 Gorshkov B.G.  ... 
doi:10.1109/lo.2016.7549714 fatcat:mkak6vararbdznwdaacjuwuaoq

Scientific Exhibits

2014 Journal of Medical Radiation Sciences  
All patients were simulated with CT and MRI before and after injection of 10 cc of Hydrogel. The first 10 patients had an additional MRI at completion of radiation.  ...  Simulation, volume generation and goals for target volume coverage and organ at risk (OAR) avoidance followed departmental protocols.  ...  Method: Point spread dose kernels were produced using the Monte Carlo simulation toolkit, GEANT4 version 9.6.p02.  ... 
doi:10.1002/jmrs.74 pmid:27759942 pmcid:PMC4263487 fatcat:ccsk62gef5g47bfugrvtwqapj4

Ion and Neutron Beams Discover New Facts from History

Anna Macková, Jan Kučera, Jan Kameník, Vladimír Havránek, Karel Kranda
2017 Nuclear Physics News  
[2, 3] ) have validated and benchmarked Monte Carlo codes/ tools for simulating the propagation of protons and carbon nuclei in tissue-like materials and also in voxel-based anthropomorphic phantoms.  ...  Monte Carlo modelling in hadrontherapy Th e well-known Monte Carlo (MC) codes FLUKA, Geant4, MCNPX, PHITS and SHIELD-HIT were initially designed for simulations in particle and nuclear physics.  ...  The Ring Cyclotron feeds the Swiss Muon Source (SμS) with six beamlines available for experiments using muons as sensitive local magnetic probes, and SINQ, a continuous spallation neutron source providing  ... 
doi:10.1080/10619127.2017.1388686 fatcat:nxj4nqnfvfc4vbslelb67hauhe

Proceedings of the World Molecular Imaging Congress 2021, October 5-8, 2021: General Abstracts

2022 Molecular Imaging and Biology  
Results: In all of the phantom and patients' MRI studies the post-processed images proved to have higher resolution and contrast as compared with images reconstructed by conventional methods.  ...  Materials and Methods: The method was tested on ACR MRI phantom and DICOM clinical MRI data. Data acquisition was performed on a commercial Siemens MRI system.  ...  The nanocluster system with a high selectivity showed the potential for fluorescence imaging and the integrating of gold and MMAE demonstrated excellent concurrent chemotherapy-radiotherapy efficacy, which  ... 
doi:10.1007/s11307-021-01693-y pmid:34982365 pmcid:PMC8725635 fatcat:4sfb3isoyfdhfbiwxfr55gvqym

Proceedings of the World Molecular Imaging Congress 2020, October 7-9, 2020: General Abstracts

2022 Molecular Imaging and Biology  
Fluorescence signal distinguished tumor cells with 90% specificity and 82.5% sensitivity.  ...  Administered systemically, nearinfrared fluorescent dye-labeled antibody targeting EGFR may be able to detect HGGs expressing modest amount of EGFR and serve as an image-guided surgical probe.  ...  Microvascular connectivity (MC) maps (Fig. 1h ) illustrate early stage coherent blood volume fluctuations (i.e. vasodilations and vasoconstrictions) in areas with sprouting tumor vessels (D3-D6), which  ... 
doi:10.1007/s11307-021-01691-0 pmid:34982363 pmcid:PMC8725637 fatcat:ipn7hwekzzh6nbsk6dr2mzuhhm
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