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Cu-nanoparticles ecotoxicity – Explored and explained?

Susana I.L. Gomes, Michael Murphy, Margrethe T. Nielsen, Søren M. Kristiansen, Mónica J.B. Amorim, Janeck J. Scott-Fordsmand
2015 Chemosphere  
doi:10.1016/j.chemosphere.2015.06.045 pmid:26142613 fatcat:hxwkjsqvw5cfbnpaaokli7tdlm

Kvantitativ undersøkelse av mulige sammenhenger mellom vurderingsform og karakterer i høyere utdanning

Monica Kristiansen, Tom Heine Nätt, Christian F. Heide
2013 Uniped  
I Heide, Kristiansen og Nätt (2012) tok vi utgangspunkt i emner gitt ved ulike avdelinger ved Høgskolen i Østfold (HiØ) og undersøkte om det gis bedre karakterer i emner hvor vurderingsformen er mappe  ... 
doi:10.3402/uniped.v36i2.21516 fatcat:3jmu2mp7qvbstkbhkp577alaeq

Purification of L-asparaginase fromE. coliby specific adsorption and desorption

Tore Kristiansen, Monica Einarsson, Lars Sundberg, Jerker Porath
1970 FEBS Letters  
doi:10.1016/0014-5793(70)80186-7 pmid:11947497 fatcat:nwmjfipvffhc5iuzqlysre4xhu

ON COMPONENT DEPENDENCIES IN COMPOUND SOFTWARE

MONICA KRISTIANSEN, RUNE WINTHER, BENT NATVIG
2010 International Journal of Reliability, Quality and Safety Engineering (IJRQSE)  
, Winther and Natvig Kristiansen, Winther and Natvig Kristiansen, Winther and Natvig Kristiansen, Winther and Natvig Fig. 11.  ...  5 10 0.4553 0.0496 0.4951 6.1 × 10 −5 11 0.4552 0.0496 0.4952 5.9 × 10 −5 12 0.4554 0.0494 0.4952 5.7 × 10 −5 13 0.4554 0.0496 0.4950 6.3 × 10 −5 14 0.4554 0.0494 0.4952 5.8 × 10 −5 Kristiansen  ...  Kristiansen, Winther and Natvig Theorem 2. Consider a general system consisting of three components. Assume further that the components' marginal reliabilities p 1 , p 2 and p 3 are known.  ... 
doi:10.1142/s0218539310003895 fatcat:2klmavdde5gxtnoygnq5wdgqle

The CORAS Framework for a Model-Based Risk Management Process [chapter]

Rune Fredriksen, Monica Kristiansen, Bjørn Axel Gran, Ketil Stølen, Tom Arthur Opperud, Theo Dimitrakos
2002 Lecture Notes in Computer Science  
CORAS is a research and technological development project under the Information Society Technologies (IST) Programme (Commission of the European Communities, Directorate-General Information Society). One of the main objectives of CORAS is to develop a practical framework, exploiting methods for risk analysis, semiformal methods for object-oriented modelling, and computerised tools, for a precise, unambiguous, and efficient risk assessment of security critical systems. This paper presents the
more » ... AS framework and the related conclusions from the CORAS project so far.
doi:10.1007/3-540-45732-1_11 fatcat:qsk75mgouna5njnfseksgefodm

Decreased NR1, NR2A, and SAP102 transcript expression in the hippocampus in bipolar disorder

Robert E. McCullumsmith, Lars V. Kristiansen, Monica Beneyto, Elizabeth Scarr, Brian Dean, James H. Meador-Woodruff
2007 Brain Research  
Objectives-Schizophrenia is associated with dysfunction of glutamatergic neurotransmission, and several studies have suggested glutamatergic abnormalities in bipolar disorder. Recent data suggest involvement of the NMDA receptor-signaling complex, which includes NMDA receptor subunits as well as associated intracellular interacting proteins critical for NMDA receptor assembly, trafficking, and activation; the most well characterized being PSD-93, PDS-95, SAP102, and NF-L. Previously, studies
more » ... m our laboratories have described changes in glutamate receptor subunit transcript and binding site expression in schizophrenia, and changes in NMDA receptor binding site expression in bipolar disorder in postmortem brain tissue. In the present work, we focus on the expression of these molecules in hippocampus in schizophrenia and bipolar affective disorder I. Methods-We performed in situ hybridization to assess hippocampal expression of the transcripts encoding NMDA receptor subunits NR1, 2A, 2B, 2C and 2D, and the transcripts for the NMDA receptor associated PSD proteins PSD-95, PSD-93, NF-L and SAP102 in subjects with schizophrenia, bipolar affective disorder I, and a comparison group. We also measured [ 3 H] CGP39653 and [ 3 H]MK-801 binding site expression in the hippocampus in schizophrenia. Results-There was a significant decrease in the expression of transcripts for NR1 and NR2A subunits and SAP102 in bipolar disorder. We did not detect any changes in these transcripts or in binding site expression in the hippocampus in schizophrenia. Conclusions-We propose that the NMDA receptor-signaling complex, including the intracellular machinery that is coupled to the NMDA receptor subunits, is abnormal in the hippocampus in bipolar disorder. These data suggest bipolar disorder might be associated with abnormalities of glutamatelinked intracellular signaling and trafficking processes.
doi:10.1016/j.brainres.2006.09.011 pmid:17113057 pmcid:PMC2900828 fatcat:56egdjhknjhldl376kliptlxku

Abnormal Glutamate Receptor Expression in the Medial Temporal Lobe in Schizophrenia and Mood Disorders

Monica Beneyto, Lars V Kristiansen, Akinwunmi Oni-Orisan, Robert E McCullumsmith, James H Meador-Woodruff
2007 Neuropsychopharmacology  
Some of these events could modify protein levels without a change in mRNA expression (You and Yin, 2000; Kristiansen et al, 2006) .  ... 
doi:10.1038/sj.npp.1301312 pmid:17299517 fatcat:jmfk7p6hvbfqzar5ab22d4as7a

Archaeological Prospection in Wetlands—Experiences and Observations from Ground-Penetrating Radar Surveys in Norwegian Bogs

Manuel Gabler, Claes Olof Johan Uhnér, Nils Ole Sundet, Alois Hinterleitner, Pål Nymoen, Monica Kristiansen, Immo Trinks
2021 Remote Sensing  
Wetlands are of immense importance for archaeological research due to excellent preservation conditions for organic material. However, the detection and registration of archaeological remains in waterlogged areas, such as peatlands, bogs, mires, or lakeshores are very challenging. Alternative methods that can support traditional archaeological registrations and that can help to survey wetlands more efficiently are needed. One goal of the "Arkeologi på nye veier" (Archaeology on new ways)
more » ... , initiated by Nye Veier AS, was to develop and test a practical solution for non-invasive geophysical surveys in wetland environments in support of traditional archaeological investigations. For that purpose, a custom GPR system for wetland investigations was assembled, tested and applied at Gausdal (Flekkefjord municipality, Agder county) in Norway within the E39-southwest infrastructure project. The GPR survey resulted in promising data, clearly showing the buried remains of an old road within the investigated area. This case study demonstrated the potential of GPR measurements in peatlands as a valuable asset for archaeological registration projects in such environments. However, despite these first encouraging results, wetlands remain very challenging environments, and realistic expectations, as well as a good understanding of the potential and limitations of this approach are a prerequisite for meaningful surveys.
doi:10.3390/rs13163170 fatcat:iq3xkrizkvfypol4crw63fr6da

Archaeological Prospection with Motorised Multichannel Ground-Penetrating Radar Arrays on Snow-Covered Areas in Norway

Manuel Gabler, Immo Trinks, Erich Nau, Alois Hinterleitner, Knut Paasche, Lars Gustavsen, Monica Kristiansen, Christer Tonning, Petra Schneidhofer, Matthias Kucera, Wolfgang Neubauer
2019 Remote Sensing  
(Monica Kristiansen), C.T., P.S.; Data processing: A.H., M.G., E.N., I.T.; Data interpretation: M.G., E.N., I.T., M.K. (Matthias Kucera); Project management: M.G., E.N., K.P.; Writing: M.G., I.T.  ... 
doi:10.3390/rs11212485 fatcat:oorvf572m5c6xjr5laogre4dge

Delineating an Unmarked Graveyard by High-Resolution GPR and pXRF Prospection: The Medieval Church Site of Furulund in Norway

Rebecca J. S. Cannell, Lars Gustavsen, Monica Kristiansen, Erich Nau
2018 Journal of Computer Applications in Archaeology  
The lack of accurate locational information on abandoned medieval and later graveyards constitutes a considerable challenge to national and local bodies tasked with their protection and management. These sites are increasingly in danger of destruction due to climatic changes, intensified farming schemes or developmental encroachment, and there is an ever-growing need to develop nonintrusive methods to ensure their detection and delineation so that they can be protected. In 2014, the Norwegian
more » ... rectorate for Cultural Heritage received alarming information on the worsening state of the medieval church site at Furulund, in the southeast of the country. A successful, cost-effective campaign using high-resolution, large-scale georadar surveys in conjunction with geochemical mapping using portable XRF was undertaken in order to delineate and characterise the graveyard so that remedial actions could be initiated and the graveyard protected. Whilst the interpretations are unique to the site, the method combination has the potential to effectively resolve detection and protection of other, similar sites in Norway and beyond.
doi:10.5334/jcaa.9 fatcat:tuynschz5ndizfy3dkm3rmfdry

A BAYESIAN HYPOTHESIS TESTING APPROACH FOR FINDING UPPER BOUNDS FOR PROBABILITIES THAT PAIRS OF SOFTWARE COMPONENTS FAIL SIMULTANEOUSLY

MONICA KRISTIANSEN, RUNE WINTHER, BENT NATVIG
2011 International Journal of Reliability, Quality and Safety Engineering (IJRQSE)  
Monica Kristiansen received a cand. scient degree in applied statistics at the Agricultural University of Norway (now Norwegian University of Life Sciences) in 2000.  ...  Kristiansen, Winther and Natvig 4 Table 1 . 1 Notation.  ... 
doi:10.1142/s021853931100410x fatcat:7oatjtblx5dqpfhu6lzqflyr4a

Response of Enchytraeus crypticus worms to high metal levels in tropical soils polluted by copper smelting

Ladislav Konečný, Vojtěch Ettler, Søren Munch Kristiansen, Mónica João Barros Amorim, Bohdan Kříbek, Martin Mihaljevič, Ondřej Šebek, Imasiku Nyambe, Janeck James Scott-Fordsmand
2014 Journal of Geochemical Exploration  
Tropical soils from the vicinity of the Mufulira copper smelter (Zambian Copperbelt) were found to contain high levels of metals, particularly in the upper parts of soil horizons. Metal concentrations varied within the ranges: 37-8980 mg Cu/kg, 3-46 mg Co/kg, b 2.5-42 mg Pb/kg, and 16-83 mg Zn/kg. The EDTA extractions indicated that a considerable percentage of the metals were bound in the "labile" fractions of the soil (up to 55% of total Cu concentration, 36% Co, 41% Pb, 30% Zn). The
more » ... ical investigation of the heavy mineral fraction of the most contaminated soil showed that the Cu is mainly present as Cu-(Fe) sulphides (chalcocite, chalcopyrite), metallic Cu, complex Cu-(Fe) oxides, and Cu-bearing sulphates. To determine the toxicity of these soils, we adopted a standardized OECD reproduction test using Enchytraeus crypticus. The number of reproduced enchytraeids correlated negatively with total Cu and Co concentrations (r = −0.97 and −0.94 at p b 0.001, respectively), and EDTA-extractable Cu (r = −0.89, p b 0.001); whereas no effects of the soil properties (pH, CEC, C org ) were observed. No reproduction was possible in soils with Cu levels N5000 mg/kg. Median effect concentration (EC50) was calculated for total Cu concentration, and corresponded to 351 mg/kg.
doi:10.1016/j.gexplo.2013.10.004 fatcat:nfqmgxmjfvfqlijvbiqmzhtqju

Use of interferon gamma-based assay to diagnose tuberculosis infection in health care workers after short term exposure

Dag Gundersen Storla, Ingun Kristiansen, Fredrik Oftung, Gro Ellen Korsvold, Monica Gaupset, Gerd Gran, Anne Kristin Øverby, Anne Margarita Dyrhol-Riise, Gunnar Aksel Bjune
2009 BMC Infectious Diseases  
We intended to assess the risk for health care workers (HCWs) of acquiring M. tuberculosis infection after exposure to patients with sputum-smear positive pulmonary tuberculosis at three University Hospitals (Ullevål, Akershus, and Haukeland) in Norway. Methods: We tested 155 exposed health care workers and 48 healthy controls both with a tuberculin skin test (Mantoux) and the T-SPOT.TB test, a recently developed interferon-γ release assays based on the M. tuberculosisspecific ESAT-6 and CFP10
more » ... ntigens, to investigate if this test might improve infection control measures. Results: Among the 155 exposed HCWs tested in this study, 27 individuals were defined as newly infected cases by TST after recent exposure, while only 3 of these had a positive T-SPOT.TB test. The number of T-SPOT.TB positives represents 11% of the individuals defined as recently infected by TST after exposure (3/27) and 2% of the total number of exposed people tested (3/155). In addition, 15 individuals had been previously defined as infected by TST before exposure of whom 2 subjects were T-SPOT.TB positive. All individuals detected as T-SPOT.TB positive belonged to the TST positive group (> 15 mm), and the percentage concordance between T-SPOT.TB and TST, including both previously and newly infected subjects, was 12% (5/42). The 48 control participants used in the study were all T-SPOT.TB negative, but 3 of these subjects were TST positive. Conclusion: Our data indicate that the frequency of latent TB in the total cohort of HCWs is 3%, whereas the rate of transmission of TB to exposed individuals is approximately 2% and occurs through exposure periods of short duration. Thus, the risk of TB transmission to HCWs following TB exposure in a hospital setting in Norway is low, and improved screening approaches will benefit from the application of specific interferon-γ release assays.
doi:10.1186/1471-2334-9-60 pmid:19432995 pmcid:PMC2690599 fatcat:tjtkpxn5jvb7blyuw27gqmc67m

Light Converts Endosymbiotic Fungus to Pathogen, Influencing Seedling Survival and Niche-Space Filling of a Common Tropical Tree, Iriartea deltoidea

Patricia Álvarez-Loayza, James F. White, Mónica S. Torres, Henrik Balslev, Thea Kristiansen, Jens-Christian Svenning, Nathalie Gil, Jae-Hyuk Yu
2011 PLoS ONE  
Pathogens are hypothesized to play an important role in the maintenance of tropical forest plant species richness. Notably, species richness may be promoted by incomplete filling of niche space due interactions of host populations with their pathogens. A potentially important group of pathogens are endophytic fungi, which asymptomatically colonize plants and are diverse and abundant in tropical ecosystems. Endophytes may alter competitive abilities of host individuals and improve host fitness
more » ... der stress, but may also become pathogenic. Little is known of the impacts of endophytes on niche-space filling of their hosts. Here we evaluate how a widespread fungal endophyte infecting a common tropical palm influences its recruitment and survival in natural ecosystems, and whether this impact is modulated by the abiotic environment, potentially constraining host niche-space filling. Iriartea deltoidea dominates many wet lowland Neotropical forests. Diplodia mutila is a common asymptomatic endophyte in mature plants; however, it causes disease in some seedlings. We investigated the effects of light availability on D. mutila disease expression. We found I. deltoidea seedlings to preferentially occur under shady conditions. Correspondingly, we also found that high light triggers endophyte pathogenicity, while low light favors endosymbiotic development, constraining recruitment of endophyte-infested seedlings to shaded understory by reducing seedling survival in direct light. Pathogenicity of D. mutila under high light is proposed to result from light-induced production of H 2 O 2 by the fungus, triggering hypersensitivity, cell death, and tissue necrosis in the palm. This is the first study to demonstrate that endophytes respond to abiotic factors to influence plant distributions in natural ecosystems; and the first to identify light as a factor influencing where an endophyte is placed on the endosymbiont-pathogen continuum. Our findings show that pathogens can indeed constrain niche-space filling of otherwise successful tropical plant species, providing unoccupied niche space for other species.
doi:10.1371/journal.pone.0016386 pmid:21305008 pmcid:PMC3031546 fatcat:ujeiyukinbecnpndkh3sinygne

Aalborg Universitet Diterpenes and other metabolites isolated from sage (Salvia officinalis L.) and their effect on the human peroxisome proliferator-activated receptor (PPAR)

Monica Jørgensen, Kathrine Christensen, Bisgaard, Kotowska, Ewa Dorota, Lars Christensen, Porskjaer, Karsten Kristiansen, M Jørgensen, K Christensen, D Kotowska, L Christensen (+1 others)
unpublished
K. (2009). Diterpenes and other metabolites isolated from sage (Salvia officinalis L.) and their effect on the human peroxisome proliferator-activated receptor (PPAR). Abstract from Nordic Natural Products Conference (NNPC) 2009, Haukadal, Iceland.
fatcat:hidiadkzmne25k7f3kroq6opc4
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