Filters








8,628 Hits in 9.5 sec

An Aggressive Subtype of Stage I Lung Adenocarcinoma with Molecular and Prognostic Characteristics Typical of Advanced Lung Cancers

Elisa Dama, Valentina Melocchi, Fabio Dezi, Stefania Pirroni, Rose Mary Carletti, Daniela Brambilla, Giovanni Bertalot, Monica Casiraghi, Patrick Maisonneuve, Massimo Barberis, Giuseppe Viale, Manuela Vecchi (+3 others)
<span title="2016-06-29">2016</span> <i title="American Association for Cancer Research (AACR)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/zm56axre7rgihh5sznxp65np5i" style="color: black;">Clinical Cancer Research</a> </i> &nbsp;
We also thank the Molecular Pathology Unit of the Molecular Medicine Program at IEO and the Division of Thoracic Surgery and the Division of Pathology at IEO.  ...  Acknowledgments We are indebted to Francesca de Santis, Flavia Troglio, and Giovanna Jodice for technical support.  ...  In this study, we moved toward the clinical application of this signature by (i) testing it in large independent cohorts of NSCLC patients; (ii) assessing the robustness of its prognostic power across  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1158/1078-0432.ccr-15-3005">doi:10.1158/1078-0432.ccr-15-3005</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27358486">pmid:27358486</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/oylgfaakzjbvxjttlrfec52hry">fatcat:oylgfaakzjbvxjttlrfec52hry</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190430221618/http://clincancerres.aacrjournals.org/content/clincanres/23/1/62.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/1c/d8/1cd8ffbe6a31fd6a449ef0798ad1ff992f1a7582.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1158/1078-0432.ccr-15-3005"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Using microarray-based subtyping methods for breast cancer in the era of high-throughput RNA sequencing

Christina Bligaard Pedersen, Finn Cilius Nielsen, Maria Rossing, Lars Rønn Olsen
<span title="2018-10-29">2018</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/wilcjb4re5hs5egpxpnhcm4lj4" style="color: black;">Molecular Oncology</a> </i> &nbsp;
Acknowledgements We thank Christos Sotirou and colleagues at the Breast Cancer Translational Research Laboratory (BCTL), Institut Jules Bordet, Brussels, Belgium, for kindly granting us access to the raw  ...  MR and FCN acquired the data. CBP and LRO analyzed and interpreted the data developed the computational framework. CBP and LRO wrote the manuscript.  ...  We show that our method outperforms existing methods and enables direct application of RNA-Seq data for molecular subtyping of breast cancer.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/1878-0261.12389">doi:10.1002/1878-0261.12389</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/5ugopa6cufhhhap6xiwdapw4wq">fatcat:5ugopa6cufhhhap6xiwdapw4wq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200305194344/https://curis.ku.dk/ws/files/218720753/Pedersen_et_al_2018_Molecular_Oncology.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/2d/62/2d6203cb28cdd78bc1fb69e82210643dcc93208c.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/1878-0261.12389"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> wiley.com </button> </a>

Expression and sub-cellular localization of an epigenetic regulator, co-activator arginine methyltransferase 1 (CARM1), is associated with specific breast cancer subtypes and ethnicity

Melissa B Davis, Xinyu Liu, Shiyao Wang, Jaxk Reeves, Andrey Khramtsov, Dezheng Huo, Olufunmilayo I Olopade
<span title="">2013</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/fgif277mw5b6xokdmmdusvygrq" style="color: black;">Molecular Cancer</a> </i> &nbsp;
+ status, other clinical variables and survival.  ...  CARM1 has distinct functions among molecular subtypes, as is indicative of its sub-cellular localization and it may function in subtype etiology.  ...  Special thanks to Sarah Gehlert and the Center of Interdisciplinary Health Disparities Research at UofC for guidance and involvement on experimental direction.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/1476-4598-12-40">doi:10.1186/1476-4598-12-40</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23663560">pmid:23663560</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3663705/">pmcid:PMC3663705</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/mj6hduwdgvfkzl5ys7w7leiwqu">fatcat:mj6hduwdgvfkzl5ys7w7leiwqu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170830081543/https://molecular-cancer.biomedcentral.com/track/pdf/10.1186/1476-4598-12-40?site=http://molecular-cancer.biomedcentral.com" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/bb/0b/bb0bac923f52216f4ff7089d65197dc0f4fe22b4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/1476-4598-12-40"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663705" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Proteome-transcriptome alignment of molecular portraits achieved by self-contained gene set analysis: Consensus colon cancer subtypes case study

Galina Glazko, Boris Zybailov, Frank Emmert-Streib, Ancha Baranova, Yasir Rahmatallah, Igor B. Rogozin
<span title="2019-08-22">2019</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a> </i> &nbsp;
Here we present a self-contained proteome level GSA of four consensus molecular subtypes (CMSs) previously established by transcriptome dissection of colon carcinoma specimens.  ...  Overall, this study proves utility of self-contained GSA approaches as a critical tool for analyzing proteomics data in general and dissecting protein-level molecular portraits of human tumors in particular  ...  Acknowledgments Support was provided in part by the NIH IDeA Networks of Biomedical Research Excellence (INBRE) grant (P20 GM103429) and by Center for Translational Pediatric Research (CTPR) NIH Center  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0221444">doi:10.1371/journal.pone.0221444</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31437237">pmid:31437237</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6705791/">pmcid:PMC6705791</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/idorq2ldg5f65mp6btyrli63cm">fatcat:idorq2ldg5f65mp6btyrli63cm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20191214052941/https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0221444&amp;type=printable" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f2/6b/f26b082a144ddd16c58c0662e847ad0c85f7a3ab.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0221444"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705791" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Pan-cancer subtyping in a 2D-map shows substructures that are driven by specific combinations of molecular characteristics

Erdogan Taskesen, Sjoerd M. H. Huisman, Ahmed Mahfouz, Jesse H. Krijthe, Jeroen de Ridder, Anja van de Stolpe, Erik van den Akker, Wim Verheagh, Marcel J. T. Reinders
<span title="2016-04-25">2016</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/tnqhc2x2aneavcd3gx5h7mswhm" style="color: black;">Scientific Reports</a> </i> &nbsp;
To progress in these applications, the trend is to move from single genome-wide measurements in a single cancer-type towards measuring several different molecular characteristics across multiple cancer-types  ...  Although current approaches shed light on molecular characteristics of various cancer-types, detailed relationships between patients within cancer clusters are unclear.  ...  Acknowledgements Publication costs for this article were sourced from the BioRange program of the Netherlands Bioinformatics Centre (NBIC), which is supported by the Netherlands Genomics Initiative (NGI  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/srep24949">doi:10.1038/srep24949</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27109935">pmid:27109935</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4842960/">pmcid:PMC4842960</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/c43ncw2dvrcq7cib4odshj4tyi">fatcat:c43ncw2dvrcq7cib4odshj4tyi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170922080941/http://www.nature.com/articles/srep24949.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/23/78/23789f9dbbc88086438e32eafad2ffd40d306450.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/srep24949"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842960" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Personalized Medicine in Cancer

Md Mizanur Rahman
<span title="2015-12-23">2015</span> <i title="Bangladesh Journals Online (JOL)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ubip3weoonbqjbtdhnmh2rjsvy" style="color: black;">Journal of Bangladesh College of Physicians and Surgeons</a> </i> &nbsp;
In this review a brief discussion on definition and molecular aspects of personalized medicine and its practical application for the management of common solid cancers are highlighted.  ...  Therapies for patients with cancer have changed gradually over the past decade, moving away from the administration of broadly acting cytotoxic drugs towards the use of more-specific therapies that are  ...  Application of personalized medicine in some common cancers: Breast Cancer: The clinical course of breast cancer varies tremendously between patients.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3329/jbcps.v32i3.26054">doi:10.3329/jbcps.v32i3.26054</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/yxx4gu4ib5cwziofczfc62dq7i">fatcat:yxx4gu4ib5cwziofczfc62dq7i</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190427214549/https://www.banglajol.info/index.php/JBCPS/article/download/26054/17453" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/fd/ca/fdca951cfee096397ecc36ff15508b3f444202f3.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3329/jbcps.v32i3.26054"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Triple negative breast cancer: Breast cancer research in evolution

Jennifer Eng-Wong, Sally Hunsberger, Jo Anne Zujewski, Jennifer Eng-Wong, Jo Anne Zujewski
<span title="2011-03-15">2011</span> <i title="IOS Press"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/v2xx3siz55bslk5xaivtv2kcbm" style="color: black;">Breast Disease</a> </i> &nbsp;
This issue contains in-depth reviews of multiple aspects of TNBC from triple negative cell lines to current clinical trials.  ...  We envision this special edition of Breast Disease focused on triple negative breast cancer (TNBC) as a "go-to" handbook accessible to clinical, translational and laboratory researchers in designing (and  ...  While the identification of multiple subtypes of breast cancer has clearly demonstrated that "lumping" different subtypes of breast cancer together is unwise due to differing biology and prognosis, we  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3233/bd-2010-0314">doi:10.3233/bd-2010-0314</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/21778576">pmid:21778576</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/3lqovnaywncttgvj3y5kwbawje">fatcat:3lqovnaywncttgvj3y5kwbawje</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20171007151337/http://content.iospress.com/download/breast-disease/bd000314?id=breast-disease%2Fbd000314" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/68/5a/685a606ebc10da2a1da1adbda0d3b08ecb0ccdde.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3233/bd-2010-0314"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Deep learning in cancer pathology: a new generation of clinical biomarkers

Amelie Echle, Niklas Timon Rindtorff, Titus Josef Brinker, Tom Luedde, Alexander Thomas Pearson, Jakob Nikolas Kather
<span title="2020-11-18">2020</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/k7cos7qqgzazliffoxrrx3awka" style="color: black;">British Journal of Cancer</a> </i> &nbsp;
These advanced approaches include inference of molecular features, prediction of survival and end-to-end prediction of therapy response.  ...  Nevertheless, routinely available tumour tissue contains an abundance of clinically relevant information that is currently not fully exploited.  ...  Moving towards clinical approval: where are we now?  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41416-020-01122-x">doi:10.1038/s41416-020-01122-x</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33204028">pmid:33204028</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/5s6uirk6fzfm7pipd2agneljee">fatcat:5s6uirk6fzfm7pipd2agneljee</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210429063018/https://www.nature.com/articles/s41416-020-01122-x.pdf?error=cookies_not_supported&amp;code=40507ce9-638d-4aa0-a29a-6701ec0e4cec" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/50/aa/50aaef126b9026f1c7d9bdfbda9895817aa957cd.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41416-020-01122-x"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Neoadjuvant Therapy in Breast Cancer [chapter]

Angela Lewis, Nathalie Johnson, Esther H
<span title="2012-02-01">2012</span> <i title="InTech"> Neoadjuvant Chemotherapy - Current Applications in Clinical Practice </i> &nbsp;
Neoadjuvant Chemotherapy -Current Applications in Clinical Practice 24 *Values are median (range).  ...  Lewis Traylor, Nathalie Johnson and Esther Han (2012). Neoadjuvant Therapy in Breast Cancer, Neoadjuvant Chemotherapy -Current Applications in Clinical Practice, Dr.  ...  This trial showed an overall response rate of 79%, and a pCR of 13% 6, 7 . 1493 patients with operable breast cancer were stratified by age, clinical tumor size, and clinical nodal status to preoperative  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5772/24805">doi:10.5772/24805</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/qon2ejfwazb2rpf24qdprlttaq">fatcat:qon2ejfwazb2rpf24qdprlttaq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190504082805/https://cdn.intechopen.com/pdfs/27545.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/fb/b7/fbb71319f95ac545dd82f3ff28ff1c7641e7ff51.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5772/24805"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Molecular epidemiology of hepatitis C virus genotypes and subtypes among injecting drug users in Hungary

B Tresó, M Takács, Á Dencs, M Dudás, A Pár, E Rusvai
<span title="2013-11-21">2013</span> <i title="European Centre for Disease Control and Prevention (ECDC)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/muzck22wczfstmm6pqm3jmwi2m" style="color: black;">Eurosurveillance</a> </i> &nbsp;
Acknowledgements We would like to acknowledge the contribution of experts in the Member States in supplying the data used for the production of this report.  ...  There is need for further research on molecular epidemiology, reservoirs, mode of transmission, clinical relevance and case fatality.  ...  ), the Czech Republic (two outbreaks, one of them H5N3 subtype) and Romania (one outbreak, H5N3 subtype).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.2807/1560-7917.es2013.18.47.20639">doi:10.2807/1560-7917.es2013.18.47.20639</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6wqmzcq6ozbcbfatvcmvfsm3mi">fatcat:6wqmzcq6ozbcbfatvcmvfsm3mi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180723002001/https://ecdc.europa.eu/sites/portal/files/media/en/publications/Publications/1111_SUR_Annual_Epidemiological_Report_on_Communicable_Diseases_in_Europe.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.2807/1560-7917.es2013.18.47.20639"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Biological Subtypes of Triple-Negative Breast Cancer

Michael Hubalek, Theresa Czech, Hannes Müller
<span title="">2017</span> <i title="S. Karger AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hnd3ugg6nnbgbcb43t3hphcwlq" style="color: black;">Breast Care</a> </i> &nbsp;
clinical application.  ...  These subtypes include mostly HER2+ breast cancer ( fig. 1 ). 25% of all TNBCs lack ER, PR, and HER2 in IHC but do not exhibit the features of the basallike subtype.  ...  Identification of patients with tumors deficient in homologous repair or HRD-like behavior moves cancer treatment towards individualized therapies.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1159/000455820">doi:10.1159/000455820</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28611535">pmid:28611535</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5465739/">pmcid:PMC5465739</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/n2lwvxc6enb77ea5fhyn4lweja">fatcat:n2lwvxc6enb77ea5fhyn4lweja</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20201103172944/https://www.karger.com/Article/Pdf/455820" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ef/f6/eff6e185f72ef7438b75b0dbc379b512e6497f9d.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1159/000455820"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465739" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

New Strategies in Ovarian Cancer: Translating the Molecular Complexity of Ovarian Cancer into Treatment Advances

J. Liu, U. A. Matulonis
<span title="2014-10-14">2014</span> <i title="American Association for Cancer Research (AACR)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/zm56axre7rgihh5sznxp65np5i" style="color: black;">Clinical Cancer Research</a> </i> &nbsp;
An improved understanding of the genomics of ovarian cancer and the separation of ovarian cancer into histologically and molecularly defined subgroups have affected drug development and clinical trial  ...  In this article, we review recent advances in the understanding of the molecular diversity of ovarian cancer as well as emerging therapeutic strategies such as new agents and biologic combinations that  ...  Table 1 lists the current oral PARPis in clinical trials for ovarian cancer and the status of ongoing studies.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1158/1078-0432.ccr-14-1312">doi:10.1158/1078-0432.ccr-14-1312</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25320365">pmid:25320365</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/g4ndgso3vvcidgoo6wudgdjvqu">fatcat:g4ndgso3vvcidgoo6wudgdjvqu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190223195547/http://pdfs.semanticscholar.org/4c73/4a62471a7ecac187b3d92a53157da4530157.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/4c/73/4c734a62471a7ecac187b3d92a53157da4530157.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1158/1078-0432.ccr-14-1312"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Lung Cancer Genomic Signatures

M. Teresa Agulló-Ortuño, Fernando López-Ríos, Luis Paz-Ares
<span title="">2010</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/c2djx4ouvbc4liw66psheqd6ke" style="color: black;">Journal of Thoracic Oncology</a> </i> &nbsp;
to identify homogenous tumor subtypes, new prognostic factors of human cancer, response to a particular treatment, etc. and thereby select the best possible therapies while decreasing the risk of toxicities  ...  In view of this, there is an urgent need to improve the diagnostic, prognostic, and therapeutic classification systems, currently based on clinicopathological criteria that do not adequately translate  ...  No reliable clinical or molecular predictors of recurrent disease are currently available.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1097/jto.0b013e3181f1900e">doi:10.1097/jto.0b013e3181f1900e</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/20736853">pmid:20736853</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/jb4zciwwhrdxfjvcsndtgbyeva">fatcat:jb4zciwwhrdxfjvcsndtgbyeva</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170927131808/http://publisher-connector.core.ac.uk/resourcesync/data/elsevier/pdf/535/aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS9zMTU1NjA4NjQxNTMxODE5MA%3D%3D.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5b/47/5b479fe1919f1b37b9667476814c9c49108dcaca.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1097/jto.0b013e3181f1900e"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Unmasking molecular profiles of bladder cancer

Xuan-Mei Piao, Young Joon Byun, Wun-Jae Kim, Jayoung Kim
<span title="">2018</span> <i title="The Korean Urological Association (KAMJE)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/wyutvwpljzcjzddqqhgfoxlpvm" style="color: black;">Investigative and Clinical Urology</a> </i> &nbsp;
Intensive studies are also being performed to understand the complex and dynamic molecular profiles of bladder cancer.  ...  The aim of this short review is to outline the current technologies being used to investigate molecular profiles and discuss biomarker candidates that have been investigated as possible diagnostic and  ...  ACKNOWLEDGMENTS WK and JK designed the study, led obtaining funding, and overviewed the literature analysis and drafting the manuscript. All authors read and approved the f inal manuscript.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.4111/icu.2018.59.2.72">doi:10.4111/icu.2018.59.2.72</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29520382">pmid:29520382</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5840121/">pmcid:PMC5840121</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/jyd3sx2mpvdf5mse4ogr4tag7a">fatcat:jyd3sx2mpvdf5mse4ogr4tag7a</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190309021354/http://pdfs.semanticscholar.org/fcd8/297b066a1d1de4bc43b0b5e070ad326de5a7.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/fc/d8/fcd8297b066a1d1de4bc43b0b5e070ad326de5a7.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.4111/icu.2018.59.2.72"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840121" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Proteomic Studies on the Management of High-Grade Serous Ovarian Cancer Patients: A Mini-Review

Melissa Bradbury, Eva Borràs, Assumpció Pérez-Benavente, Antonio Gil-Moreno, Anna Santamaria, Eduard Sabidó
<span title="2021-04-25">2021</span> <i title="MDPI AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/2zwku6u6nfdcri773tpisi6ldi" style="color: black;">Cancers</a> </i> &nbsp;
High-grade serous ovarian cancer (HGSC) remains the most common and deadly subtype of ovarian cancer.  ...  The past decade has seen significant advances in the clinical management and molecular understanding of HGSC following the publication of the Cancer Genome Atlas (TCGA) researchers and the introduction  ...  Conflicts of Interest: The authors declare no conflict of interest.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/cancers13092067">doi:10.3390/cancers13092067</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33922979">pmid:33922979</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8123279/">pmcid:PMC8123279</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/a4yqootww5aavnw2g6dpl44eci">fatcat:a4yqootww5aavnw2g6dpl44eci</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210715160336/https://repositori.upf.edu/bitstream/handle/10230/47675/Bra_Can_Pro.pdf;jsessionid=F9A2B55F3048EA13BFD9473058908ECB?sequence=1" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f6/e7/f6e70dbacec87ac33b37e70608f6e540cfc4e9a0.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/cancers13092067"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> mdpi.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123279" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>
&laquo; Previous Showing results 1 &mdash; 15 out of 8,628 results