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Causal Relational Learning [article]

Babak Salimi, Harsh Parikh, Moe Kayali, Sudeepa Roy, Lise Getoor, Dan Suciu
2020 arXiv   pre-print
Causal inference is at the heart of empirical research in natural and social sciences and is critical for scientific discovery and informed decision making. The gold standard in causal inference is performing randomized controlled trials; unfortunately these are not always feasible due to ethical, legal, or cost constraints. As an alternative, methodologies for causal inference from observational data have been developed in statistical studies and social sciences. However, existing methods
more » ... isting methods critically rely on restrictive assumptions such as the study population consisting of homogeneous elements that can be represented in a single flat table, where each row is referred to as a unit. In contrast, in many real-world settings, the study domain naturally consists of heterogeneous elements with complex relational structure, where the data is naturally represented in multiple related tables. In this paper, we present a formal framework for causal inference from such relational data. We propose a declarative language called CaRL for capturing causal background knowledge and assumptions and specifying causal queries using simple Datalog-like rules.CaRL provides a foundation for inferring causality and reasoning about the effect of complex interventions in relational domains. We present an extensive experimental evaluation on real relational data to illustrate the applicability of CaRL in social sciences and healthcare.
arXiv:2004.03644v1 fatcat:ymm26dvnkbg4fjjoskm74xn3ke

Treatment of L5-S1 Spondyloptosis With Single-Stage Surgery Through the Posterior Approach-Case Report-

2004 Neurologia medico-chirurgica  
J Bone Joint Surg Am 37: 767-797, 1955 8) Boxall D, Bradford DS, Winter RB, Moe JH: Management of severe spondylolisthesis in children and adolescents.  ...  Spine 19: 710-715, 1994 2) Akay KM, Baysefer A, Kayali H, Beduk A, Timurkaynak E: Fracture and lateral dislocation of the T12-L1 vertebrae without neurological deficit. Case report.  ... 
doi:10.2176/nmc.44.386 pmid:15347218 fatcat:7h3rae7mordxxditshjbesf5sq

Performance evaluation of palm oil clinker as coarse aggregate in high strength lightweight concrete

Rasel Ahmmad, Mohd Zamin Jumaat, U. Johnson Alengaram, Syamsul Bahri, Muhammad Abdur Rehman, Huzaifa bin Hashim
2016 Journal of Cleaner Production  
The highest MOE of about 34.8 GPa was obtained for the mix P100 and it is higher than previous studies (Gao et al., 1997; Kayali et al., 2003) in HSLWC.  ...  MOE/f cu ratio was only 348.  ... 
doi:10.1016/j.jclepro.2015.08.043 fatcat:yudbvlgc5na3nalm6q2j4tenai

The effect of steel fibres on the enhancement of flexural and compressive toughness and fracture characteristics of oil palm shell concrete

Kim Hung Mo, Kathy Khai Qian Yap, U. Johnson Alengaram, Mohd Zamin Jumaat
2014 Construction and Building Materials  
Therefore, the mix N1 was found to have higher MOE than the mix K1 as lower porosity leads to higher MOE [42] .  ...  [5] and Kayali et al. [37] reported that there was no significant effect of steel fibres on the compressive strength for Lytag and sintered fly ash aggregate concrete.  ...  Further, the contribution of fibres to stress redistribution caused lower strain and improved the MOE as for the same stress level the strain produced in the OPSC was higher compared to the SFOPSC.  ... 
doi:10.1016/j.conbuildmat.2013.12.103 fatcat:ehxfxxauzrdzddmci2b53skfoa


Soon Poh YAP, U. Johnson ALENGARAM, Mohd. Zamin JUMAAT
2015 Journal of Civil Engineering and Management  
The effect of l/d and V f on the MOE was observed for all mixes; the higher the l/d and V f values, the lower the MOE.  ...  Table 4 shows the values of the modulus of elasticity (MOE) for all mixes. As expected, the addition of steel fibres improved the MOE of OPSFRC.  ... 
doi:10.3846/13923730.2014.897970 fatcat:hyfonuhok5f7rci3n2xxsxlote

Antisense oligonucleotides in neurological disorders

Claudia D. Wurster, Albert C. Ludolph
2018 Therapeutic Advances in Neurological Disorders  
Du L, Kayali R, Bertoni C, et al. Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum.  ...  The most com- monly used are 2'-O-methyl (2'-O-Me) and 2'-O-methoxyethyl (2'-MOE) oligonucleotides.  ... 
doi:10.1177/1756286418776932 pmid:29854003 pmcid:PMC5971383 fatcat:mnt7jakkizafxjyeoazbjhlioi

Determining Material Suitability for Low-Rise Housing in the Philippines: Physical and Mechanical Properties of the Bamboo Species Bambusa blumeana

Corinna Salzer, Holger Wallbaum, Marina Alipon, Luis Felipe Lopez
2017 BioResources  
The MOE was given by the slope of the linear part of the load-deformation diagram.  ...  and the MOE at fifth percentile were Emean = 13100 MPa and E0.05 = 8600 MPa, respectively.  ... 
doi:10.15376/biores.13.1.346-369 fatcat:gk6gdcyqebfotgrbif2ft6wp44

Polycyclic Aromatic Hydrocarbons in Food - Scientific Opinion of the Panel on Contaminants in the Food Chain

2008 EFSA Journal  
In the updated risk assessment the MOE approach should be used, if appropriate.  ...  For high level consumers, the respective MOEs were 10,800, 9,500, 9,900 and 9,600. These MOEs indicate a low concern for consumer health at the average estimated dietary exposures.  ... 
doi:10.2903/j.efsa.2008.724 fatcat:z2va4phl5nempa77stxamizfq4

The earthquake awareness levels of undergraduate students

Erol Sözen
2019 Journal of Pedagogical Research  
These results may also be associated with Kayalı (2018) and Aksoy and Sözen (2013) . In these studies, gender was accepted as a variable.  ...  Natural disasters can be listed as avalanches, floods, landslides, droughts, volcano eruptions, frost, storms, earthquakes and so on (Moe & Pathranarakul, 2006; Şahin & Sipahioğlu, 2007) .  ... 
doi:10.33902/jpr.2019254175 fatcat:bjaxmyx33vc63ird5yion7mp3e

Bioactive Polyphenolic Compounds Showing Strong Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus 2

Ahmed Kandeil, Ahmed Mostafa, Omnia Kutkat, Yassmin Moatasim, Ahmed A. Al‐Karmalawy, Adel A. Rashad, Ahmed E. Kayed, Azza E. Kayed, Rabeh El-Shesheny, Ghazi Kayali, Mohamed A. Ali
2021 Pathogens  
to confirm the proposed mechanism of action as Mpro inhibitors based on their promising in vitro findings towards viral replication rather than adsorption through molecular docking studies using the MOE  ... 
doi:10.3390/pathogens10060758 pmid:34203977 pmcid:PMC8232731 fatcat:pyjyesahszebldkd575j3hrsoy


Mohammad Momeen Ul Islam
And with 10% replacement of OPC by silica fume can reduce about 60% of passing charge compare to OPC based concrete (Ahmed, Kayali, & Anderson, 2008) .  ...  They observed that the MOE of concrete is more likely dependent on the aggregates strength rather than the strength of the paste.  ... 
doi:10.6084/m9.figshare.16570806.v1 fatcat:26ubsiajqfehbm5odt7s6vcqmi

Deliver the promise: RNAs as a new class of molecular entities for therapy and vaccination

Ai-Ming Yu, Mei-Juan Tu
2021 Pharmacology and Therapeutics  
Du L, Kayali R, Bertoni C, Fike F, Hu H, Iversen PL, and Gatti RA (2011) Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery  ...  Nusinersen (or ASO-10-27), comprised of only phosphorothioate linkage, 2'-MOE on each ribose, and some methylated nucleobases ( Figure 4B) , was designed to act as a SSO ( Figure 3B ) to modulate SMN  ... 
doi:10.1016/j.pharmthera.2021.107967 fatcat:bpdzbezbira2pev6d2z24noarq

The mechanistic insight of a specific interaction between 15d-Prostaglandin-J2 and eIF4A suggests an evolutionary conserved role across species

So Jeong Yun, Hyunjoon Kim, Seung-Hyun Jung, Joon Hyun Kim, Jeong Eun Ryu, N. Jiten Singh, Jouhyun Jeon, Jin-Kwan Han, Cheol-Hee Kim, Sanguk Kim, Sung Key Jang, Woo Jae Kim
2018 Biology Open  
., 2006; Kayali et al., 2005; Murry et al., 1986; Kloner and Rezkalla, 2006; McDunn and Cobb, 2005; Lin et al., 2006) .  ...  Cα RMSD was calculated using MOE (Chemical Computing Group, 2008) . The model structure of eIF4A-1 was energyminimized using AMBER9 (Case et al., 2006) .  ... 
doi:10.1242/bio.035402 fatcat:bacc4qq7mzezfbsyzpj42ye2be

Computational docking reveals evolutionary conservation of a specific interaction between 15d-Prostaglandin-J2 and eIF4A [article]

So Jeong Yun, Hyunjoon Kim, Seung Gee Lee, Seung-Hyun Jung, Joon Hyun Kim, Jeong Eun Ryu, N. Jiten Singh, Jouhyun Jeon, Jin-Kwan Han, Cheol-Hee Kim, Sanguk Kim, Kwang S. Kim (+2 others)
2017 bioRxiv   pre-print
., 2006; Kayali et al., 2005; Kloner and Rezkalla, 2006; Lin et al., 2006; McDunn and Cobb, 2005; Murry et al., 1986) .  ...  Cα rmsd was calculated using MOE (ChemicalComputingGroup, 2008) . The model structure of eIF4A-1 was energyminimized using AMBER9 (Case et al., 2006) .  ... 
doi:10.1101/237610 fatcat:zvrrsuu46nafrfjw4qnut45zei

The Fibroblast Growth Factor signaling pathway

David M. Ornitz, Nobuyuki Itoh
2015 Wiley Interdisciplinary Reviews: Developmental Biology  
Hu MC, Shiizaki K, Kuro-o M, Moe OW. Fibroblast Growth Factor 23 and Klotho: physiology and pathophysiol- ogy of an endocrine network of min- eral metabolism.  ...  Kurosu H, Ogawa Y, Miyoshi M, Yamamoto M, Nandi A, Rosenblatt KP, Baum MG, Schiavi S, Hu MC, Moe OW, et al. Regulation of Fibroblast Growth Factor-23 signaling by klotho.  ... 
doi:10.1002/wdev.176 pmid:25772309 pmcid:PMC4393358 fatcat:mcru2faw5nggneodckbs3u35ny
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