Filters








31,733 Hits in 7.3 sec

Dynamics on global brain networks at the neuronal resolution

Masanori Shimono, Ryota Kobayashi
2015 BMC Neuroscience  
We used a Multi-timescale adaptive threshold (MAT) model for the single neuron model, which has proven to be one of the most accurate models for reproducing the spike trains of a variety of cortical neurons  ...  Furthermore, the cortical network used in our study includes "weight" of connections [8] .  ...  We used a Multi-timescale adaptive threshold (MAT) model for the single neuron model, which has proven to be one of the most accurate models for reproducing the spike trains of a variety of cortical neurons  ... 
doi:10.1186/1471-2202-16-s1-p128 pmcid:PMC4697663 fatcat:k5nadqlmtfd5bed7cc4lsbi3q4

The Internet Diabetes Self-Management Workshop for American Indians and Alaska Natives

V. B. B. Jernigan, K. Lorig
2011 Health Promotion Practice  
White matter damage impairs adaptive recovery more than cortical damage in an in silico model of activity-dependent plasticity.  ...  Using this model, they compared the impact of neuronal cell loss or axonal dysfunction on the ability of the system to generate, maintain, and recover synapses.  ...  This study was presented at the Neurobiology of Disease in Children Conference: Symposium on Injury to the Preterm Brain and Cerebral Palsy, in conjunction with the 37th Annual Meeting of the Child Neurology  ... 
doi:10.1177/0883073809338627 pmid:19745092 pmcid:PMC3840913 fatcat:yuthwoi3dfeqliti6pzrmhhwo4

The Internet Diabetes Self-Management Workshop for American Indians and Alaska Natives

Valarie Blue Bird Jernigan, Kate Lorig
2010 Health Promotion Practice  
White matter damage impairs adaptive recovery more than cortical damage in an in silico model of activity-dependent plasticity.  ...  Using this model, they compared the impact of neuronal cell loss or axonal dysfunction on the ability of the system to generate, maintain, and recover synapses.  ...  This study was presented at the Neurobiology of Disease in Children Conference: Symposium on Injury to the Preterm Brain and Cerebral Palsy, in conjunction with the 37th Annual Meeting of the Child Neurology  ... 
doi:10.1177/1524839909335178 pmid:20534807 fatcat:gh5bdlul45fytl6tsezjgm7kc4

Modelling cortical laminar connectivity in the macaque brain [article]

Ittai Shamir, Yaniv Assaf
2020 bioRxiv   pre-print
This model uses a granularity-based approach to define a set of rules that expands cortical connections to the laminar level.  ...  In this work, we revisit laminar-level connectivity in the macaque brain using a whole-brain MRI-based approach.  ...  By using a data-driven model, we were able to combine results from diffusion-weighted imaging and T1-weighted imaging in order to estimate cortical laminar connectivity across the macaque brain.  ... 
doi:10.1101/2020.07.19.210526 fatcat:nuy7kolaqba6revo6zdhbjcmca

Adaptation of Brain Functional and Structural Networks in Aging

Annie Lee, Nagulan Ratnarajah, Ta Anh Tuan, Shen-Hsing Annabel Chen, Anqi Qiu, Yong Liu
2015 PLoS ONE  
In addition, we found that the structural connectivity of the PFC with the temporal lobe was fully mediated by the temporal cortical thickness, suggesting that the brain morphology plays an important role  ...  This study employed structural MRI, resting-state fMRI (rs-fMRI), and high angular resolution diffusion imaging (HARDI), and examined the functional and structural reorganization of the PFC in aging using  ...  Lastly, in examining whether brain atrophy would account for age-related alterations in the connectivity strength, cortical thickness was also entered into the above regression model.  ... 
doi:10.1371/journal.pone.0123462 pmid:25875816 pmcid:PMC4398538 fatcat:hgtppb4mjvhsnn5fm5elw35mla

Whole brain comparative anatomy using connectivity blueprints

Rogier B Mars, Stamatios N Sotiropoulos, Richard E Passingham, Jerome Sallet, Lennart Verhagen, Alexandre A Khrapitchev, Nicola Sibson, Saad Jbabdi
2018 eLife  
The blueprints provide a common reference space that allows us to navigate between brains of different species, identify homologous cortical areas, or to transform whole cortical maps from one species  ...  We illustrate how this approach can be used to compare human and macaque brains.  ...  of diffusion orientations using BedpostX, using a crossing fiber model limited to three fiber directions (Behrens et al. 2007) .  ... 
doi:10.7554/elife.35237 pmid:29749930 pmcid:PMC5984034 fatcat:3bonifhfprfgtpefeo4bn6kfr4

Multivariate analysis of thalamo-cortical connectivity loss in TBI

Jeffrey Duda, Brian Avants, Junghoon Kim, Hui Zhang, Sunil Patel, John Whyte, James Gee
2008 2008 IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops  
with the mean diffusion within the thalamus and cortical regions.  ...  Our objective is to use both modalities to build subject-specific, quantitative models of fiber connections in order to discover effects specific to a neural system.  ...  This model is used to identify the particular cortical regions to which thalamic connections are compromised.  ... 
doi:10.1109/cvprw.2008.4562992 dblp:conf/cvpr/DudaAKZPWG08 fatcat:hvc2r6telbep3iqoxsqdwa3kt4

Whole brain comparative anatomy using connectivity blueprints [article]

Rogier B. Mars, Stamatios N. Sotiropoulos, Richard E. Passingham, Jerome Sallet, Lennart Verhagen, Alexandr A. Krapitchev, Nicola Sibson, Saad Jbabdi
2018 bioRxiv   pre-print
The blueprints provide a common reference space that allows us to navigate between brains of different species, identify homologue cortical areas, or to transform whole cortical maps from one species to  ...  We illustrate how this approach can be used to compare human and macaque brains.  ...  A crossing fibre model adapted to multi--shell data (Jbabdi et al. 2012 ) was fitted to the data prior to tractography.  ... 
doi:10.1101/245209 fatcat:doywhiylvrclvpa2qsu3kf5ude

Human connectomics

Timothy EJ Behrens, Olaf Sporns
2012 Current Opinion in Neurobiology  
Collectively, advances in human connectomics open up the possibility of studying how brain connections mediate regional brain function and thence behaviour.  ...  substrate, and the architecture of large-scale networks connecting sets of brain regions may be analyzed in detail.  ...  Figure adapted from [38] . b. (b) These connectional differences can be used to delineate cortical regions.  ... 
doi:10.1016/j.conb.2011.08.005 pmid:21908183 pmcid:PMC3294015 fatcat:3ivb6cw6vrhrjksrp2faxrq5lm

MRI of the Neonatal Brain: A Review of Methodological Challenges and Neuroscientific Advances

Jessica Dubois, Marianne Alison, Serena J. Counsell, Hertz‐Pannier Lucie, Petra S. Hüppi, Manon J.N.L. Benders
2020 Journal of Magnetic Resonance Imaging  
The use of age-specific image postprocessing tools is also essential, as signal and contrast differ from the adult brain.  ...  In this review article, we aim to highlight recent and representative studies using the various techniques available: anatomical MRI, quantitative MRI (relaxometry, diffusion MRI), multiparametric approaches  ...  provided by the different diffusion models in the developing brain according to the age of newborns and the cortical regions.  ... 
doi:10.1002/jmri.27192 pmid:32420684 fatcat:ttakecloanaupet2ej7uk5nzxi

An adaptable neuromorphic model of orientation selectivity based on floating gate dynamics

Priti Gupta, C. M. Markan
2014 Frontiers in Neuroscience  
In this paper we use a novel time-staggered Winner Take All circuit, that exploits the adaptation dynamics of floating gate transistors, to model an adaptive cortical cell that demonstrates Orientation  ...  Adaptation and self-organization are the two basic principles that underlie any cognitive function that the brain performs.  ...  A major step toward building such systems would be to understand the underlying principles that the brain uses to accomplish adaptation.  ... 
doi:10.3389/fnins.2014.00054 pmid:24765062 pmcid:PMC3980111 fatcat:cwavpp2i6zc3tolhgvuyzmf5ha

An MRI-based, data-driven model of cortical laminar connectivity [article]

Ittai Shamir, Yaniv Assaf
2020 medRxiv   pre-print
datasets into a novel way of exploring whole-brain tissue-level connectivity.  ...  Our model addresses three principal cortical building blocks: cortical layer definitions (laminar grouping), vertical connections (intraregional, within the cortical microcircuit and subcortex) and horizontal  ...  While the model does not offer individual region-specific models of cortical circuitry, it offers a more generalized whole-brain microcircuit model that is adapted regionally based on an atlas of granularity  ... 
doi:10.1101/2020.06.02.20120303 fatcat:xz7k2zib6rhszhgtlack3srj5a

Linking immune-mediated damage to neurodegeneration in multiple sclerosis: could network-based MRI help?

Sergiu Groppa, Gabriel Gonzalez-Escamilla, Arman Eshaghi, Sven G Meuth, Olga Ciccarelli
2021 Brain Communications  
There is an unmet need for a conceptual shift from a dualistic view of multiple sclerosis pathology, involving either inflammatory demyelination or neurodegeneration, to integrative dynamic models of brain  ...  We propose that MRI-based brain networks characterization is essential for better delineating ongoing pathology and elaboration of particular mechanisms that may serve for accurate modelling and prediction  ...  Notably, the brain network hubs are not only important because their topological centrality supports integrative network processing and adaptive responses, but also because their high connectivity makes  ... 
doi:10.1093/braincomms/fcab237 pmid:34729480 pmcid:PMC8557667 fatcat:r5kvglx3jfdnznq4rtozc6x54i

Diffuse neural coupling mediates complex network dynamics through the formation of quasi-critical brain states

Eli J. Müller, Brandon R. Munn, James M. Shine
2020 Nature Communications  
A potential solution may lie in a unique aspect of neurobiology, which is that numerous brain systems contain diffuse synaptic connectivity.  ...  Here, we demonstrate that increasing diffuse cortical coupling within a validated biophysical corticothalamic model traverses the system through a quasi-critical regime in which spatial heterogeneities  ...  cortical connectivity, and diffuse all-to-all uniform cortical connectivity.  ... 
doi:10.1038/s41467-020-19716-7 pmid:33303766 fatcat:q6vzadn7zrcn3apqu2lp4boeji

The NonHuman Primate Neuroimaging & Neuroanatomy Project

Takuya Hayashi, Yujie Hou, Matthew F Glasser, Joonas A Autio, Kenneth Knoblauch, Miho Inoue-Murayama, Tim Coalson, Essa Yacoub, Stephen Smith, Henry Kennedy, David C Van Essen
2021 NeuroImage  
diffusion MRI compare with long-distance connections measured using tract tracing.  ...  macaque and marmoset monkeys using protocols and methods adapted from the HCP; (ii) acquire quantitative invasive tract-tracing data for cortical and subcortical projections to cortical areas; and (iii  ...  Acknowledgements This study is supported by a grant Brain/MINDS -beyond from References under revision of this special issue of NeuroImage Autio, J.A., Zhu, Q., Li, X., Glasser, M.F., Schwiedrzik,  ... 
doi:10.1016/j.neuroimage.2021.117726 pmid:33484849 pmcid:PMC8079967 fatcat:tfv3sm6xpjfnfj2uarpqwnyc5u
« Previous Showing results 1 — 15 out of 31,733 results