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A Study of the PDGF Signaling Pathway with PRISM
<span title="2011-09-08">2011</span>
<i title="Open Publishing Association">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/qzezkwolyvf33pglm2jldjklca" style="color: black;">Electronic Proceedings in Theoretical Computer Science</a>
</i>
In this paper, we apply the probabilistic model checker PRISM to the analysis of a biological system -- the Platelet-Derived Growth Factor (PDGF) signaling pathway, demonstrating in detail how this pathway ...
We show that quantitative verification can yield a better understanding of the PDGF signaling pathway. ...
For instance, the process algebra bio-PEPA is used to model and analyze the NF-kappaB pathway [7] ; Petri nets are used for quantitative predictive modeling of C.elegans vulval development [6] ; and ...
<span class="external-identifiers">
<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.4204/eptcs.67.7">doi:10.4204/eptcs.67.7</a>
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Formal Methods in Molecular Biology Dagstuhl Seminar
<span class="release-stage">unpublished</span>
Formal logical models play an increasing role in the newly emerging eld of Systems Biology. ...
Abstracts of the presentations given during the seminar as well as abstracts of seminar results and ideas are put together in this paper. ...
Keywords: Process algebras, NF-κB pathway, modelling, analysis Joint work of: Ciocchetta, Federica; Degasperi, Andrea; Heath, John; Hillston, Jane Modelling and analysis of the NF-κB pathway in Bio-PEPA ...
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Therapeutic targets for rheumatoid arthritis: lessons from animal models
<span title="">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research & Therapy</a>
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To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
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<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3573">doi:10.1186/ar3573</a>
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Overview of biotherapy in rheumatoid arthritis (RA)
<span title="">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research & Therapy</a>
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To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
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<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3596">doi:10.1186/ar3596</a>
<a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332514/">pmcid:PMC3332514</a>
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Skeletal involvement in the pathogenesis and outcomes of rheumatoid arthritis and osteoarthritis
<span title="">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research & Therapy</a>
</i>
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
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<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3571">doi:10.1186/ar3571</a>
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Cancer immunotherapy; integration of T cell biology with nanogel- and vector-technology in translational research
<span title="">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research & Therapy</a>
</i>
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
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<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3564">doi:10.1186/ar3564</a>
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Peptide therapy in sepsis and inflammation: a novel strategy to suppress inflammation
<span title="">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research & Therapy</a>
</i>
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
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Abnormal osteogenesis in osteoarthritis: gone with the Wnt?
<span title="">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research & Therapy</a>
</i>
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
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<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3574">doi:10.1186/ar3574</a>
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Autoimmune arthritis caused by altered thymic T-cell selection due to a mutation of the ZAP-70 gene
<span title="">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research & Therapy</a>
</i>
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
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<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3565">doi:10.1186/ar3565</a>
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Evidence for synovial fibroblasts spreading rheumatoid arthritis
<span title="">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research & Therapy</a>
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To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
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<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3570">doi:10.1186/ar3570</a>
<a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332411/">pmcid:PMC3332411</a>
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Future direction of pathogenesis and treatment for rheumatic disorders
<span title="">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research & Therapy</a>
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To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
<span class="external-identifiers">
<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3556">doi:10.1186/ar3556</a>
<a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332471/">pmcid:PMC3332471</a>
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Maintenance of mitochondrial DNA copy number is essential for osteoclast survival
<span title="">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research & Therapy</a>
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To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
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<a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332442/">pmcid:PMC3332442</a>
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Peptide therapy in sepsis and inflammation: A novel strategy to suppress inflammation
<span title="">2016</span>
<i title="Elsevier BV">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/doyhwbvmozan5mzji6xml5iipq" style="color: black;">Immunobiology</a>
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To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
<span class="external-identifiers">
<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.imbio.2016.06.049">doi:10.1016/j.imbio.2016.06.049</a>
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Fcγ receptor targeting in RA
<span title="">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research & Therapy</a>
</i>
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
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<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3572">doi:10.1186/ar3572</a>
<a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332397/">pmcid:PMC3332397</a>
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GI-REASONS: a novel 6-month, prospective, randomized, open-label, blinded end point (PROBE) trial
<span title="">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research & Therapy</a>
</i>
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis. ...
Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway. ...
Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis. ...
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<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3664">doi:10.1186/ar3664</a>
<a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332426/">pmcid:PMC3332426</a>
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