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A Study of the PDGF Signaling Pathway with PRISM

Qixia Yuan, Jun Pang, Sjouke Mauw, Panuwat Trairatphisan, Monique Wiesinger, Thomas Sauter
<span title="2011-09-08">2011</span> <i title="Open Publishing Association"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/qzezkwolyvf33pglm2jldjklca" style="color: black;">Electronic Proceedings in Theoretical Computer Science</a> </i> &nbsp;
In this paper, we apply the probabilistic model checker PRISM to the analysis of a biological system -- the Platelet-Derived Growth Factor (PDGF) signaling pathway, demonstrating in detail how this pathway  ...  We show that quantitative verification can yield a better understanding of the PDGF signaling pathway.  ...  For instance, the process algebra bio-PEPA is used to model and analyze the NF-kappaB pathway [7] ; Petri nets are used for quantitative predictive modeling of C.elegans vulval development [6] ; and  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.4204/eptcs.67.7">doi:10.4204/eptcs.67.7</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/pgl4iaqqlvbitjkfjd4a37kjhe">fatcat:pgl4iaqqlvbitjkfjd4a37kjhe</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20160910162448/http://satoss.uni.lu/members/sjouke/papers/YPMTWS11.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/fc/39/fc3924193bd83c843a230175c70f98b8c06b0c6d.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.4204/eptcs.67.7"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Formal Methods in Molecular Biology Dagstuhl Seminar

Rainer Breitling, David Gilbert, Monika Heiner, Corrado Priami
<span class="release-stage">unpublished</span>
Formal logical models play an increasing role in the newly emerging eld of Systems Biology.  ...  Abstracts of the presentations given during the seminar as well as abstracts of seminar results and ideas are put together in this paper.  ...  Keywords: Process algebras, NF-κB pathway, modelling, analysis Joint work of: Ciocchetta, Federica; Degasperi, Andrea; Heath, John; Hillston, Jane Modelling and analysis of the NF-κB pathway in Bio-PEPA  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/sr3u24hkmbhcfmuzxgi4xzq64a">fatcat:sr3u24hkmbhcfmuzxgi4xzq64a</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180517203945/http://drops.dagstuhl.de/opus/volltexte/2009/1997/pdf/09091_abstracts_collection.1997.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/aa/67/aa67c683e5981fa4f1329202485ebb77856ca953.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Therapeutic targets for rheumatoid arthritis: lessons from animal models

Yoichiro Iwakura, Shinobu Saijo, Susumu Nakae, Noriyuki Fujikado, Harumichi Ishigame, Masanori Murayama
<span title="">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research &amp; Therapy</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3573">doi:10.1186/ar3573</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332513/">pmcid:PMC3332513</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/lf2tq75u6zehhdf4ay7lsjiyym">fatcat:lf2tq75u6zehhdf4ay7lsjiyym</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20120513141438/http://arthritis-research.com/content/pdf/ar3566.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/32/4f/324f1f9c19c8507267fd05cbcce803e867fe54b5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3573"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332513" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Overview of biotherapy in rheumatoid arthritis (RA)

Tsutomu Takeuchi, Hideto Kameda
<span title="">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research &amp; Therapy</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3596">doi:10.1186/ar3596</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332514/">pmcid:PMC3332514</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/quhi2gjtlbd6jmbsvqlxzr6dxq">fatcat:quhi2gjtlbd6jmbsvqlxzr6dxq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170815081321/https://arthritis-research.biomedcentral.com/track/pdf/10.1186/ar3595?site=arthritis-research.biomedcentral.com" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5d/c0/5dc0550f738ca899c2d1a9bddc5f4ab77b3dea01.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3596"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332514" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Skeletal involvement in the pathogenesis and outcomes of rheumatoid arthritis and osteoarthritis

Jean-Pierre Pelletier
<span title="">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research &amp; Therapy</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3571">doi:10.1186/ar3571</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332410/">pmcid:PMC3332410</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/vbvskdxecndela7iqvvtfrfeum">fatcat:vbvskdxecndela7iqvvtfrfeum</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20120513141438/http://arthritis-research.com/content/pdf/ar3566.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/32/4f/324f1f9c19c8507267fd05cbcce803e867fe54b5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3571"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332410" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Cancer immunotherapy; integration of T cell biology with nanogel- and vector-technology in translational research

Hiroshi Shiku
<span title="">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research &amp; Therapy</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3564">doi:10.1186/ar3564</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332465/">pmcid:PMC3332465</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/iynz4xtwg5dqdewnycb52u2udy">fatcat:iynz4xtwg5dqdewnycb52u2udy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20120513141438/http://arthritis-research.com/content/pdf/ar3566.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/32/4f/324f1f9c19c8507267fd05cbcce803e867fe54b5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3564"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332465" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Peptide therapy in sepsis and inflammation: a novel strategy to suppress inflammation

Hidechika Okada, Alan Okada
<span title="">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research &amp; Therapy</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3595">doi:10.1186/ar3595</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332496/">pmcid:PMC3332496</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/uzr2hqjoxnc2vm3klfd7oklo6i">fatcat:uzr2hqjoxnc2vm3klfd7oklo6i</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170815081321/https://arthritis-research.biomedcentral.com/track/pdf/10.1186/ar3595?site=arthritis-research.biomedcentral.com" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5d/c0/5dc0550f738ca899c2d1a9bddc5f4ab77b3dea01.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3595"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332496" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Abnormal osteogenesis in osteoarthritis: gone with the Wnt?

Daniel Lajeunesse, Thomas F Chan, Aline Delalandre, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Élie Abed
<span title="">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research &amp; Therapy</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3574">doi:10.1186/ar3574</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332466/">pmcid:PMC3332466</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/eruowr44hfgjjpatkkevfxfld4">fatcat:eruowr44hfgjjpatkkevfxfld4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20120513141438/http://arthritis-research.com/content/pdf/ar3566.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/32/4f/324f1f9c19c8507267fd05cbcce803e867fe54b5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3574"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332466" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Autoimmune arthritis caused by altered thymic T-cell selection due to a mutation of the ZAP-70 gene

Yoshinaga Ito, Shimon Sakaguchi
<span title="">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research &amp; Therapy</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3565">doi:10.1186/ar3565</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332505/">pmcid:PMC3332505</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/hmni2iumazf6pcnwdiqandhh7u">fatcat:hmni2iumazf6pcnwdiqandhh7u</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20120513141438/http://arthritis-research.com/content/pdf/ar3566.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/32/4f/324f1f9c19c8507267fd05cbcce803e867fe54b5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3565"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332505" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Evidence for synovial fibroblasts spreading rheumatoid arthritis

Ulf Müller-Ladner, Stefanie Lefèvre, Birgit Zimmermann, Ingo H Tarner, Robert Dinser, Thomas Pap, Steffen Gay, Elena Neumann
<span title="">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research &amp; Therapy</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3570">doi:10.1186/ar3570</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332411/">pmcid:PMC3332411</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/xlefjll5mbeetorj24ojjna4dq">fatcat:xlefjll5mbeetorj24ojjna4dq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20120513141438/http://arthritis-research.com/content/pdf/ar3566.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/32/4f/324f1f9c19c8507267fd05cbcce803e867fe54b5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3570"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332411" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Future direction of pathogenesis and treatment for rheumatic disorders

Steffen Gay
<span title="">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research &amp; Therapy</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3556">doi:10.1186/ar3556</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332471/">pmcid:PMC3332471</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/c2zds4jw4rc3retj3vtobs6fzm">fatcat:c2zds4jw4rc3retj3vtobs6fzm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20120513141438/http://arthritis-research.com/content/pdf/ar3566.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/32/4f/324f1f9c19c8507267fd05cbcce803e867fe54b5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3556"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332471" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Maintenance of mitochondrial DNA copy number is essential for osteoclast survival

Tsuyoshi Miyazaki, Shuuichi Mori, Kazuhiro Shigemoto, Nils-Goran Larsson, Takeshi Nakamura, Shigekaki Kato, Tomoki Nakashima, Hiroshi Takayanagi, Sakae Tanaka
<span title="">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research &amp; Therapy</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3650">doi:10.1186/ar3650</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332442/">pmcid:PMC3332442</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/4w5pyroawvavdn7fvbh6ntwlbq">fatcat:4w5pyroawvavdn7fvbh6ntwlbq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170815081321/https://arthritis-research.biomedcentral.com/track/pdf/10.1186/ar3595?site=arthritis-research.biomedcentral.com" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5d/c0/5dc0550f738ca899c2d1a9bddc5f4ab77b3dea01.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3650"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332442" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Peptide therapy in sepsis and inflammation: A novel strategy to suppress inflammation

Hidechika Okada, Alan Okada
<span title="">2016</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/doyhwbvmozan5mzji6xml5iipq" style="color: black;">Immunobiology</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.imbio.2016.06.049">doi:10.1016/j.imbio.2016.06.049</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6pnr3r4fpvhabfdg37hq6bhzhu">fatcat:6pnr3r4fpvhabfdg37hq6bhzhu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170815081321/https://arthritis-research.biomedcentral.com/track/pdf/10.1186/ar3595?site=arthritis-research.biomedcentral.com" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5d/c0/5dc0550f738ca899c2d1a9bddc5f4ab77b3dea01.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.imbio.2016.06.049"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a>

Fcγ receptor targeting in RA

Toshiyuki Takai, Akira Nakamura, Akiko Tobinai, Shota Endo, Masanori Inui
<span title="">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research &amp; Therapy</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3572">doi:10.1186/ar3572</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332397/">pmcid:PMC3332397</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/fkj36dv7mjd3hin3ce52rzqine">fatcat:fkj36dv7mjd3hin3ce52rzqine</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20120513141438/http://arthritis-research.com/content/pdf/ar3566.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/32/4f/324f1f9c19c8507267fd05cbcce803e867fe54b5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3572"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332397" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

GI-REASONS: a novel 6-month, prospective, randomized, open-label, blinded end point (PROBE) trial

Byron Cryer, Chunming Li, Lee S Simon, Gurkirpal Singh, Martin J Stillman, Manuela Berger
<span title="">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/m5rx6mbo4jhzdownmvkt3dg5vq" style="color: black;">Arthritis Research &amp; Therapy</a> </i> &nbsp;
To unravel the signaling pathways of YopM, we tested for phosphorylation of MAP-kinases (ERK, AKT and p-38) and activation of NF-KB signaling by Western Blot analysis.  ...  Finally, knockdown of PNBP1 led to reduction of the NF-B activation, suggesting that PNBP1 is an important modulator of the NF-B signaling pathway.  ...  Thus, this study aimed to explore the involvement of the Synoviolin in fibrosis process of RA using mice model of liver fibrosis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3664">doi:10.1186/ar3664</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3332426/">pmcid:PMC3332426</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/bbkr2po755dzngmtw3qbckhmmy">fatcat:bbkr2po755dzngmtw3qbckhmmy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170815081321/https://arthritis-research.biomedcentral.com/track/pdf/10.1186/ar3595?site=arthritis-research.biomedcentral.com" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5d/c0/5dc0550f738ca899c2d1a9bddc5f4ab77b3dea01.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/ar3664"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332426" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>
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