A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Filters
Modelling the impact of neurovascular coupling impairments on BOLD-based functional connectivity at rest
2020
NeuroImage
Preserved Fulltext
The aim of our simulation study, therefore, was to investigate the influence of impaired neurovascular coupling on resting-state BOLD-FC. ...
Functional magnetic resonance imaging (fMRI) of blood oxygenation level dependent (BOLD) signals during the resting-state is widely used to study functional connectivity (FC) of slowly fluctuating ongoing ...
Acknowledgements The authors thank the German Research Foundation DFG [grant numbers PR 1039/6-1, SO 1336/4-1] for funding. ...
doi:10.1016/j.neuroimage.2020.116871
pmid:32335261
fatcat:z6xfqeigpzddxmjo2az2jmkrzq
Pathophysiological interference with neurovascular coupling - when imaging based on hemoglobin might go blind
2010
Frontiers in Neuroenergetics
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf.
Local activation studies as well as studies investigating functional connectivity between brain regions of the resting brain provide a rapidly increasing body of knowledge on brain function in humans and ...
Local activation studies as well as studies investigating functional connectivity between brain regions of the resting brain provide a rapidly increasing body of knowledge on brain function in humans and ...
Citation : Lindauer U, Dirnagl U, Füchtemeier M, Böttiger C, Offenhauser N, Leithner C and Royl G (2010) Pathophysiological interference with neurovascular coupling -when imaging based on hemoglobin ...
doi:10.3389/fnene.2010.00025
pmid:20953238
pmcid:PMC2955428
fatcat:4izqjunusjazvpgkwcch3nia5m
Integration of multimodal neuroimaging methods: a rationale for clinical applications of simultaneous EEG-fMRI
2015
Functional Neurology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf.
Finally, the use of this approach to evaluate the functional connectivity of resting-state networks would extend the applications of EEG-fMRI to uncooperative or unconscious patients. ...
Integration of multimodal neuroimaging methods: a rationale for clinical applications of simultaneous EEG-fMRI KEY WORDS: BOLD, epilepsy, neurovascular coupling, pre-surgical mapping, resting-state networks ...
, and therefore able to provide only indirect information on neural activity, based on the phenomenon of "neurovascular coupling", i.e. the relationship that exists between neural activity at cellular ...
doi:10.11138/fneur/2015.30.1.009
fatcat:ssykgisdejh5zfz3vluaq6xi4u
Alterations in Functional Network Topology Within Normal Hemispheres Contralateral to Anterior Circulation Steno-Occlusive Disease: A Resting-State BOLD Study
2022
Frontiers in Neurology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2022; you can also visit the original URL.
The file type is application/pdf.
The purpose of this study was to assess spatially remote effects of hemodynamic impairment on functional network topology contralateral to unilateral anterior circulation steno-occlusive disease (SOD) ...
The BOLD baseline was used to analyze network connectivity contralateral to the diseased hemispheres of SOD patients. ...
A challenge to such paradigms, however, rests in the nature of BOLD functional network connectivity, which is influenced both by changes in neurovascular coupling and true neural connections (27, 28) ...
doi:10.3389/fneur.2022.780896
pmid:35392638
pmcid:PMC8980268
fatcat:e3ab2eccqbaajbv67qccqoisge
Longitudinal Multimodal fMRI to Investigate Neurovascular Changes in Spontaneously Hypertensive Rats
2020
Journal of Neuroimaging
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Here, we use a longitudinal functional MRI (fMRI) protocol to assess the impact of hypertension on neurovascular coupling in spontaneously hypertensive rats (SHRs). ...
To further understand this, it is advantageous to study neurovascular coupling as hypertension progresses in a rodent model. ...
in a number of brain regions in hypertensive subjects, as well as disruption to functional connectivity. 3 The mechanisms behind these changes in neurovascular coupling are currently unclear, although ...
doi:10.1111/jon.12753
pmid:32648648
fatcat:fvosrn6fknftbjvlz5ncpp7hfy
Neurovascular coupling in humans: Physiology, methodological advances and clinical implications
2015
Journal of Cerebral Blood Flow and Metabolism
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Herein, with particular focus on humans, we review the present mechanistic understanding of neurovascular coupling and highlight current approaches to assess these responses and the application in health ...
management of this critical physiological function. ...
We are at an embryonic stage regarding neurovascular coupling function using an in vivo human model. ...
doi:10.1177/0271678x15617954
pmid:26661243
pmcid:PMC4821024
fatcat:e74fdrfokzfipndlj7grx7cjhm
Separating vascular and neuronal effects of age on fMRI BOLD signals
[article]
2020
arXiv
pre-print
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Other Versions
We review current approaches to dissociate neuronal and vascular components of BOLD-fMRI of regional activity and functional connectivity. ...
Accurate identification of brain function is necessary to understand the neurobiology of cognitive ageing, and thereby promote well-being across the lifespan. ...
latencies of neuronal responses were not directly measured).
23
Dynamic causal modelling Dynamic Causal Modelling (DCM) is a model-based approach to studying brain connectivity (Friston et al., 2003 ...
arXiv:1912.02899v2
fatcat:tq4mkl776vdzpialwczs5hgama
Neurovascular dysfunction in vascular dementia, Alzheimer's and atherosclerosis
2018
BMC Neuroscience
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
Understanding the mechanisms of neurovascular coupling in health and disease may enable us to develop potential therapies to prevent the breakdown of neurovascular coupling in the treatment of vascular ...
Atherosclerosis is a chronic syndrome affecting the integrity and function of major blood vessels including those that supply the brain, and it is therefore hypothesised that atherosclerosis impairs cerebral ...
Acknowledgements I would like to thank the University of Sheffield for funding my PhD studentship as part of the Neuroimaging in Cardiovascular Disease (NICAD) Network. ...
doi:10.1186/s12868-018-0465-5
pmid:30333009
pmcid:PMC6192291
fatcat:v6f22goktfbmjiwtvhykjjx2vy
Aberrant Coupling Between Resting-State Cerebral Blood Flow and Functional Connectivity in Wilson's Disease
2019
Frontiers in Neural Circuits
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Functional connectivity strength (FCS) and CBF were calculated based on standard gray mask. ...
Whether the coupling of CBF and functional connectivity is imbalanced in WD remains largely unknown. ...
AUTHOR CONTRIBUTIONS All authors listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication. ...
doi:10.3389/fncir.2019.00025
pmid:31057370
pmcid:PMC6482267
fatcat:4typv3s7azbtxjubokttlxb5ny
Considerations for resting state functional MRI and functional connectivity studies in rodents
2015
Frontiers in Neuroscience
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf.
Resting state functional MRI (rs-fMRI) and functional connectivity mapping have become widely used tools in the human neuroimaging community and their use is rapidly spreading into the realm of rodent ...
These types of interwoven human and animal experiments have a potentially large impact on neuroscience and clinical practice. ...
The BOLD signal relies on consistent neurovascular coupling to represent neural activity in a reliable manner. ...
doi:10.3389/fnins.2015.00269
pmid:26300718
pmcid:PMC4525377
fatcat:izgtvld2k5fwdh4jdsqy63vlsm
Differential effects of aquaporin-4 channel inhibition on BOLD fMRI and Diffusion fMRI responses in rat visual cortex
[article]
2020
bioRxiv
pre-print
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Those results further confirm the implications of astrocytes in the neurovascular coupling mechanism underlying BOLD fMRI, while DfMRI relies on other, not astrocyte-mediated mechanisms. ...
The contribution of astrocytes to the BOLD fMRI and DfMRI responses in visual cortex of mice following visual stimulation were investigated an aquaporin 4 (AQP4) channel blocker, TGN-020, acting as an ...
Interfering with astrocyte function should, thus, impact BOLD fMRI responses, but not necessarily neural responses which have been shown to persist unaltered after neurovascular coupling inhibition [19 ...
doi:10.1101/2020.01.24.917849
fatcat:eef76ypvhzhvxi5htjsv6eqwpy
Disturbed neurovascular coupling in type 2 diabetes mellitus patients: Evidence from a comprehensive fMRI analysis
2019
NeuroImage: Clinical
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
Previous studies presumed that the disturbed neurovascular coupling to be a critical risk factor of cognitive impairments in type 2 diabetes mellitus (T2DM), but distinct clinical manifestations were lacked ...
Consequently, we decided to investigate the neurovascular coupling in T2DM patients by exploring the MRI relationship between neuronal activity and the corresponding cerebral blood perfusion. ...
Acknowledgements The authors thank the clinical and the nursing team of the Endocrinology Department in Tangdu Hospital for their cooperation with work on involving participants. ...
doi:10.1016/j.nicl.2019.101802
pmid:30991623
pmcid:PMC6447740
fatcat:olt5qfllezhelope4p4wwtpioq
Neurovascular Coupling During Visual Stimulation in Multiple Sclerosis: A MEG-fMRI Study
2018
Neuroscience
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
Here, we tested the hypothesis that neurovascular coupling is impaired in MS. ...
Despite altered neuronal and vascular responses, neurovascular coupling appears to be preserved in MS, at least within the range of damage and disability studied here. ...
Based on the vascular impairments reported in MS, we predicted that the MS group would have a reduced hemodynamic response to stimulation, and that neurovascular coupling in the visual cortex would be ...
doi:10.1016/j.neuroscience.2018.03.018
pmid:29580963
pmcid:PMC6458991
fatcat:jek4ppfx3vfsrav7adpyqrvq3q
Alcohol induced region-dependent alterations of hemodynamic response: implications for the statistical interpretation of pharmacological fMRI studies
2010
Experimental Brain Research
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf.
Furthermore, the present study revealed a potential pitfall associated with the statistical interpretation of pharmacological fMRI studies based on the general linear model: if the functional form of the ...
Yet, few studies have used the blood oxygenation level dependent functional magnetic resonance imaging method (BOLD fMRI) to map how alcohol alters brain functions, as fMRI relies on neurovascular coupling ...
on neurovascular coupling mechanisms. ...
doi:10.1007/s00221-010-2277-4
pmid:20502888
pmcid:PMC2885301
fatcat:iqymnqfznzaidfcljkamw25key
Imaging Functional Recovery Following Ischemic Stroke: Clinical and Preclinical fMRI Studies
2019
Journal of Neuroimaging
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Functional magnetic resonance imaging (fMRI) studies of patients in the months and years following stroke have given some insight into how the brain recovers lost functions. ...
Preclinical models of ischemic stroke aim to enhance understanding of the biology underlying recovery following stroke. ...
activity and neurovascular coupling. ...
doi:10.1111/jon.12668
pmid:31608550
fatcat:nv5krqhjhffizdwtzkaw2ti3wm
« Previous
Showing results 1 — 15 out of 749 results