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Development of an Error Model for a Factory-Calibrated Continuous Glucose Monitoring Sensor with 10-Day Lifetime

Martina Vettoretti, Cristina Battocchio, Giovanni Sparacino, Andrea Facchinetti
2019 Sensors  
Factory-calibrated continuous glucose monitoring (FC-CGM) sensors are new devices used in type 1 diabetes (T1D) therapy to measure the glucose concentration almost continuously for 10–14 days without requiring  ...  The aim of this paper is to develop a model of the error of FC-CGM sensors. The dataset used contains 79 FC-CGM traces collected by the Dexcom G6 sensor.  ...  The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.  ... 
doi:10.3390/s19235320 pmid:31816886 pmcid:PMC6928894 fatcat:wsgmknd7v5ey3o4ts7vlxxghgi

Factory-Calibrated Continuous Glucose Monitoring: How and Why It Works, and the Dangers of Reuse Beyond Approved Duration of Wear

Gregory P. Forlenza, Taisa Kushner, Laurel H. Messer, R. Paul Wadwa, Sriram Sankaranarayanan
2019 Diabetes Technology & Therapeutics  
factory-calibrated CGMs, and finally present two cases demonstrating the dangers of utilizing exploits in commercial systems to prolong sensor life.  ...  Continuous glucose monitors (CGM) display real-time glucose values enabling greater glycemic awareness with reduced management burden.  ...  Libre Flash Glucose Monitoring (FGM) System as the first factory-calibrated glucose monitoring system with a published MARD of 11.4%. 7 On March 27, 2018 the FDA approved the Dexcom G6 as the first  ... 
doi:10.1089/dia.2018.0401 pmid:30817171 pmcid:PMC6477582 fatcat:fhxed45p3fba7m5ahkp6njt73u

Accuracy of the Dexcom G6 Glucose Sensor during Aerobic, Resistance, and Interval Exercise in Adults with Type 1 Diabetes

Florian H. Guillot, Peter G. Jacobs, Leah M. Wilson, Joseph El Youssef, Virginia B. Gabo, Deborah L. Branigan, Nichole S. Tyler, Katrina Ramsey, Michael C. Riddell, Jessica R. Castle
2020 Biosensors  
The accuracy of continuous glucose monitoring (CGM) sensors may be significantly impacted by exercise.  ...  We evaluated the impact of three different types of exercise on the accuracy of the Dexcom G6 sensor. Twenty-four adults with type 1 diabetes on multiple daily injections wore a G6 sensor.  ...  Although the general accuracy of the latest factory-calibrated Dexcom G6 system has been examined [32, 33] , no study has yet assessed the impact that exercise has on the accuracy of this sensor.  ... 
doi:10.3390/bios10100138 pmid:33003524 fatcat:ne2nnf4wxzbntngeujhgzoulwe

Optical Sensors in Continuous Glucose Monitoring for the Diagnosis of Diabetes

Israr Ahmed, Nan Jiang, Xinge Shao, Mohamed Elsherif, Fahad Alam, Ahmed E. Salih, Haider Butt, Ali Kemal Yetisen
2022 Sensors & Diagnostics  
Diabetes has recently become the leading cause of death worldwide. So far, there is no effective treatment to cure or prevent diabetes, but good blood control through glucose monitoring can...  ...  mm long (90-degree insertion) 15 mm long (90-degree insertion) Calibration Frequency (per day) Min: 2 (3-4Recommended) 0 (factory calibration) 0 (factory calibration) 2 (every 12 hours) Sensing Molecule  ...  The results showed that the produced holographic glucose sensor performed well in continuous monitoring of blood plasma from 7 subjects without data lag or hysteresis, and 100% measurements were in the  ... 
doi:10.1039/d1sd00030f fatcat:xijl3cpsdjc4boxxsd6jgvcqiy

Novel methods of continuous glucose monitoring and telehealth in the improvement of diabetes care: a narrative review

Jerzy Hohendorff, Leszek Czupryniak, Grzegorz Dzida, Piotr Fichna, Przemyslawa Jarosz-Chobot, Tomasz Klupa, Malgorzata Mysliwiec, Agnieszka Szadkowska, Dorota Zozulinska-Ziolkiewicz, Maciej Malecki
2021 Archives of Medical Science  
In contrast to glucometers, continuous glucose monitoring (CGM) devices do not require finger-stick blood samples, but instead measure BG via percutaneous or subcutaneous sensors.  ...  It also compares different CGM devices and examines how the convenience of sharing CGM data in telehealth applies to the current coronavirus-19 pandemic.  ...  Acknowledgments We wish to thank Rafał Szot (Proper Medical Writing, Warsaw, Poland) for help with preparation of the manuscript. This work was supported by the Abbott company (no award/grant number).  ... 
doi:10.5114/aoms/139025 fatcat:3bjov6mzabauxlvibc6zkiashe

Current Diabetes Technology: Striving for the Artificial Pancreas

Natalie Allen, Anshu Gupta
2019 Diagnostics  
Continuous glucose monitors (CGM) allow patients to observe and discern trends in their glycemic control.  ...  Diabetes technology has continually evolved over the years to improve quality of life and ease of care for affected patients.  ...  Funding: The authors received no funding for this manuscript. Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/diagnostics9010031 pmid:30875898 pmcid:PMC6468523 fatcat:7qtcuh5nhrflhackcwxqwzzicq

Flash Glucose Monitoring: A Review of the Literature with a Special Focus on Type 1 Diabetes

Giulia Mancini, Maria Berioli, Elisa Santi, Francesco Rogari, Giada Toni, Giorgia Tascini, Roberta Crispoldi, Giulia Ceccarini, Susanna Esposito
2018 Nutrients  
Continuous Glucose Monitoring (iCGM) or Flash Glucose Monitoring (FGM).  ...  Frequent glucose monitoring allows the adjustment of insulin therapy to improve metabolic control with near-normal blood glucose concentrations.  ...  The main advantages of factory calibration compared to user calibration are elimination of fingersticks required for calibration and avoiding potential errors during the calibration process (e.g., an unsuitable  ... 
doi:10.3390/nu10080992 pmid:30060632 fatcat:fgt5skvw45bl7pbsatszifbae4

What Nephrologists Should Know about the Use of Continuous Glucose Monitoring in Type 2 Diabetes Mellitus Patients on Chronic Hemodialysis

Faiza Lamine, Menno Pruijm, Virginie Bahon, Anne Zanchi
2022 Kidney and Dialysis  
Continuous glucose monitoring (CGM) is increasingly proposed to T2D patients on hemodialysis (HD), although data regarding flash monitoring systems (FMSs) and real-time CGM (rtCGM) in HD patients are limited  ...  Despite these shortcomings, professional CGM has the potential to become an integral part of glucose monitoring of HD patients treated with insulin.  ...  Institutional Review Board Statement: Not applicable. Informed Consent Statement: Not applicable. Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/kidneydial2030042 fatcat:snbksm7rd5hjhgqfiaxcsc7zrq

Continuous glucose monitoring: review of promising technologies

Monika Klimek, Tytus Tulwin, M. Kulisz, M. Szala, M. Badurowicz, W. Cel, M. Chmielewska, Z. Czyż, K. Falkowicz, J. Kujawska, T. Tulwin
2019 MATEC Web of Conferences  
In this paper we describe current and developing continuous glucose monitoring technologies and their usefulness in promoting optimal glycemic control, influence on personalized diabetes managements and  ...  the functioning of patients.  ...  glucose, a monitor to display the information, and a transmitter that transmits the sensor data to the monitor.  ... 
doi:10.1051/matecconf/201925202012 fatcat:zjwmvciga5dldp2me7er6lm5wi

Monitoring of Pediatric Type 1 Diabetes

Brynn E. Marks, Joseph I. Wolfsdorf
2020 Frontiers in Endocrinology  
Although fingerstick blood glucose monitoring has been the standard of care for decades, ongoing rapid technological developments have resulted in increasingly widespread use of continuous glucose monitoring  ...  This article reviews recommendations for self-monitoring of glucose and ketones in pediatric T1D with particular emphasis on CGM and factors that impact the accuracy and real-world use of this technology  ...  ACKNOWLEDGMENTS The authors are grateful to Julie Slaats, RN, CPNP, CDE, and Kristina Kissiova, MD for their critical review of this article.  ... 
doi:10.3389/fendo.2020.00128 pmid:32256447 pmcid:PMC7089921 fatcat:vdo2imhkmbh4vc27zcfqntktya

Continuous Glucose Monitoring Integration in Clinical Practice: A Stepped Guide to Data Review and Interpretation

Grazia Aleppo, Kimberly Webb
2018 Journal of Diabetes Science and Technology  
The advent of continuous glucose monitoring (CGM) technology has transformed the approach to diabetes care.  ...  Evidence of CGM clinical benefits has also increased exponentially in the last decade.  ...  With factory-calibrated sensors, CGM may replace the need for SMBG in the near future.  ... 
doi:10.1177/1932296818813581 pmid:30453772 pmcid:PMC6610596 fatcat:2htsxdp225gppm25sq7tu6apg4

Automated Insulin Delivery: Easy Enough to Use in Primary Care?

Michael Heile, Betty Hollstegge, Laura Broxterman, Albert Cai, Kelly Close
2020 Clinical Diabetes  
This article aims to help primary care and endocrinology providers better understand the components, differences, limitations, and potential fit of these systems into clinical practice.  ...  There are three automated insulin delivery devices on the U.S. market, two of which are currently approved by the U.S. Food and Drug Administration.  ...  ACKNOWLEDGMENTS The authors thank Rayhan Lal, Dana Lewis, Steph Habif, Jim Hirsch, Christopher Snider, Christopher Angell, and Gary Scheiner for their help in preparing the manuscript.  ... 
doi:10.2337/cd20-0050 pmid:33384472 pmcid:PMC7755048 fatcat:ggdghyontzdtddnfyqdkmjosom

Differences Between Flash Glucose Monitor and Fingerprick Measurements

Odd Martin Staal, Heidi Marie Umbach Hansen, Sverre Christian Christiansen, Anders Lyngvi Fougner, Sven Magnus Carlsen, Øyvind Stavdahl
2018 Biosensors  
Freestyle Libre (FL) is a factory calibrated Flash Glucose Monitor (FGM).  ...  The biases seem to persist in days 2⁻7 of sensor usage.  ...  The introduction of factory calibration means that a different model needs to be applied for systems like the FL.  ... 
doi:10.3390/bios8040093 pmid:30336581 fatcat:ftrnndspgzer5enlacz45s35pm

Investigating pipeline and state of the art blood glucose biosensors to formulate next steps

Anthony G.A. Aggidis, Jeffrey D. Newman, George A. Aggidis
2015 Biosensors & bioelectronics  
Ten years on from a review in the twentieth issue of this journal, this contribution assess the direction research in the field of glucose sensing for diabetes is headed and various technologies to be  ...  The emphasis of this review was placed on the home blood glucose testing market.  ...  This will allow blood glucose data, insulin information and also continuous glucose monitoring readings and trends to be viewable on a wireless handheld device (Dexcom, 2012) .  ... 
doi:10.1016/j.bios.2015.05.071 pmid:26143465 fatcat:6fcup7y2bvbn7flqjmxswbnmie

Glucose Measurement and Control in Patients with Type 1 or Type 2 Diabetes

Lutz Heinemann, Dorothee Deiss, Thorsten Siegmund, Sandra Schlüter, Michael Naudorf, Simone von Sengbusch, Karin Lange, Guido Freckmann
2019 Experimental and clinical endocrinology & diabetes  
Acknowledgement Our heartfelt thanks go to the many colleagues who have helped us with constructive comments.  ...  German Diabetes Association: Clinical Practice Guidelines This is a translation of the DDG clinical practice guideline published in: Diabetologie 2019; 14 (Suppl 2): S119-S141  ...  company specifications Dexcom G6 CGM System Dexcom G6 Sensor From 2 years up to 10 days Yes, Android, iOS, App, Smartwatch/ Apple Watch Smart/ Apple Watch No Factory calibrated optional  ... 
doi:10.1055/a-1018-9090 pmid:31860924 fatcat:dphkglbtk5fmjesharte6zhyyi
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