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Modeling Chemotaxis Reveals the Role of Reversed Phosphotransfer and a Bi-Functional Kinase-Phosphatase

Marcus J. Tindall, Steven L. Porter, Philip K. Maini, Judith P. Armitage, Christopher V. Rao
<span title="2010-08-19">2010</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ch57atmlprauhhbqdf7x4ytejm" style="color: black;">PLoS Computational Biology</a> </i> &nbsp;
These two mechanisms enable the bifunctional kinase/phosphatase activity of CheA 3 to integrate and tune the sensory output of each signaling cluster to produce a balanced response.  ...  Here we demonstrate, using a mathematical model, how the outputs of the two signaling clusters may be integrated.  ...  Analysis of the model revealed two interesting features of the signaling network, both of which rely on reversed phosphotransfer from RR-Ps to CheA.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pcbi.1000896">doi:10.1371/journal.pcbi.1000896</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/20808885">pmid:20808885</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2924250/">pmcid:PMC2924250</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/wtvsisjlunbr5l2mcdad6rmxqu">fatcat:wtvsisjlunbr5l2mcdad6rmxqu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20171206001353/https://core.ac.uk/download/pdf/6185342.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/6a/b6/6ab658983bb1e2bc8cf7e9e06c3568329c110cc3.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pcbi.1000896"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924250" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Split Histidine Kinases Enable Ultrasensitivity and Bistability in Two-Component Signaling Networks

Munia Amin, Steven L. Porter, Orkun S. Soyer, Jason M. Haugh
<span title="2013-03-07">2013</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ch57atmlprauhhbqdf7x4ytejm" style="color: black;">PLoS Computational Biology</a> </i> &nbsp;
Here, we explore the functional role of "split kinases" where the ATP binding and phosphotransfer activities of a conventional histidine kinase are split onto two distinct proteins that form a complex.  ...  Genomic analyses reveal that up 1.7% of all identified histidine kinases have the potential to be split and bifunctional.  ...  In addition to its phosphotransfer function, CheA3 is also a phosphatase towards CheY6-P [7] . cheA3 mutants retaining phosphotransfer functions but lacking phosphatase activity do not support chemotaxis  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pcbi.1002949">doi:10.1371/journal.pcbi.1002949</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23505358">pmid:23505358</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3591291/">pmcid:PMC3591291</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/uedtm42h4naetosrsze7nclxky">fatcat:uedtm42h4naetosrsze7nclxky</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20171015140515/http://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002949&amp;type=printable" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/6d/ea/6deaa6e798c33c790c53f4005f489fe37c9b6457.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pcbi.1002949"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591291" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Phosphate Sink Containing Two-Component Signaling Systems as Tunable Threshold Devices

Munia Amin, Varun B. Kothamachu, Elisenda Feliu, Birgit E. Scharf, Steven L. Porter, Orkun S. Soyer, Feilim Mac Gabhann
<span title="2014-10-30">2014</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ch57atmlprauhhbqdf7x4ytejm" style="color: black;">PLoS Computational Biology</a> </i> &nbsp;
In this motif, a single histidine kinase (HK) phosphotransfers reversibly to two separate output response regulator (RR) proteins.  ...  Bacterial two-component signaling systems offer a rich diversity of sensory systems that are built around a core phosphotransfer reaction between histidine kinases and their output response regulator proteins  ...  We found that when the phosphotransfer reactions are modelled as bi-molecular reactions, the system is not capable of bistability (see Text S2 and S2).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pcbi.1003890">doi:10.1371/journal.pcbi.1003890</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25357192">pmid:25357192</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4214558/">pmcid:PMC4214558</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/yix5zdt3brbx7ad63d6wbfka7y">fatcat:yix5zdt3brbx7ad63d6wbfka7y</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20171015144551/http://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1003890&amp;type=printable" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/4a/ff/4aff2404af8af0cc17927ba2ff93f9adae873d68.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pcbi.1003890"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214558" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Multistep Signaling in Nature: A Close-Up of Geobacter Chemotaxis Sensing

Marta A. Silva, Carlos A. Salgueiro
<span title="2021-08-21">2021</span> <i title="MDPI AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/3loumxx7kzamnlu4h6x3xoz6ay" style="color: black;">International Journal of Molecular Sciences</a> </i> &nbsp;
Finally, the structural and functional properties of a new family of MCP found in Geobacter sulfurreducens are revisited.  ...  Two G. sulfurreducens MCP—GSU0582 and GSU0935—are members of a new family of chemotaxis sensor proteins containing a periplasmic PAS-like sensor domain with a c-type heme.  ...  Conflicts of Interest: The authors declare no conflict of interest.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/ijms22169034">doi:10.3390/ijms22169034</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34445739">pmid:34445739</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8396549/">pmcid:PMC8396549</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/uhct4fqojjgs5hnepanlwr5tc4">fatcat:uhct4fqojjgs5hnepanlwr5tc4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210825205542/https://res.mdpi.com/d_attachment/ijms/ijms-22-09034/article_deploy/ijms-22-09034-v2.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ad/a0/ada00f00095cadbc10eb57c3c71f3520b4163667.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/ijms22169034"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> mdpi.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396549" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Conformational Transitions that Enable Histidine Kinase Autophosphorylation and Receptor Array Integration

Anna R. Greenswag, Alise Muok, Xiaoxiao Li, Brian R. Crane
<span title="">2015</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/nk6zopmzsjfizb6z5kztdu477y" style="color: black;">Journal of Molecular Biology</a> </i> &nbsp;
) and support a lower extent of chemotaxis [29, 30] .  ...  A new crystal structure of the most active dimerization-plus-kinase unit (P3P4) reveals trans-directing interactions between the tether connecting P3 to P2-P1 and the adjacent ATP-binding (P4) domain.  ...  This work was also supported by a grant from the National Institutes of Health (R01 GM066775) to BRC.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.jmb.2015.10.015">doi:10.1016/j.jmb.2015.10.015</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26522934">pmid:26522934</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4721237/">pmcid:PMC4721237</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/qkpok6yyurdizj7m74twxuhfs4">fatcat:qkpok6yyurdizj7m74twxuhfs4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200211012907/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4721237&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ae/10/ae107099104732b93ac6395039e3a8e7980d02d9.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.jmb.2015.10.015"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721237" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

The pathogenicity island encoded PvrSR/RcsCB regulatory network controls biofilm formation and dispersal inPseudomonas aeruginosa PA14

Helga Mikkelsen, Kailyn Hui, Nicolas Barraud, Alain Filloux
<span title="2013-06-28">2013</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/f55g362z2zdsnfvbumwdj3b53i" style="color: black;">Molecular Microbiology</a> </i> &nbsp;
While PvrS acts as a kinase that enhances RcsB activity, RcsC has a dual function, first as a phosphorelay, and second as a phosphatase.  ...  We have previously showed that the RcsB response regulator activates expression of the cupD genes, which leads to the production of CupD fimbriae and increased attachment.  ...  Acknowledgements The authors wish to thank Victoria Wright and Miguel Cámara at the University of Nottingham for carrying out the microarray analysis, Cerith Jones for help with the structural analysis  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/mmi.12287">doi:10.1111/mmi.12287</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23750818">pmid:23750818</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3842833/">pmcid:PMC3842833</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/stvp3cslqncnxo7dci7gvhhwfe">fatcat:stvp3cslqncnxo7dci7gvhhwfe</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190426224123/http://spiral.imperial.ac.uk/bitstream/10044/1/65714/2/The%20pathogenicity%20island%20encoded%20PvrSR/RcsCB%20regulatory%20network%20controls%20biofilm%20formation%20and%20dispersal%20in%20Pseudomonas%20aeruginosa%e2%80%85PA14.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/8f/64/8f64210abe3dd730d1a70659078ed4455e045f0c.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/mmi.12287"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842833" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Unlimited multistability and Boolean logic in microbial signalling

Varun B. Kothamachu, Elisenda Feliu, Luca Cardelli, Orkun S. Soyer
<span title="2015-06-03">2015</span> <i title="The Royal Society"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/kdv34qlmv5gsfphm6vnme655ia" style="color: black;">Journal of the Royal Society Interface</a> </i> &nbsp;
These systems are generally known as two-component systems comprising histidine kinase (HK) receptors and response regulator proteins engaging in phosphotransfer reactions.  ...  Using two experimentally studied examples of two-component systems implementing hybrid HKs, we show that bistability and implementation of logic functions are possible under biologically feasible reaction  ...  We acknowledge insightful discussions with Carsten Wiuf and Steven Porter.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1098/rsif.2015.0234">doi:10.1098/rsif.2015.0234</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26040599">pmid:26040599</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4528588/">pmcid:PMC4528588</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/xocrys3ynbglbgnjjogxkar2qm">fatcat:xocrys3ynbglbgnjjogxkar2qm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190227181323/http://pdfs.semanticscholar.org/84aa/d2d0b83a0e18e0e7e182969dbc7baa81b663.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/84/aa/84aad2d0b83a0e18e0e7e182969dbc7baa81b663.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1098/rsif.2015.0234"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528588" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Comparative structural bioinformatics analysis of Bacillus amyloliquefaciens chemotaxis proteins within Bacillus subtilis group

Anna Yssel, Oleg Reva, Ozlem Tastan Bishop
<span title="2011-10-13">2011</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/pxrodjfapjez7ne4f2w6lxh2ri" style="color: black;">Applied Microbiology and Biotechnology</a> </i> &nbsp;
planlarliln B960 1 Y2 B. amyloliquefaciens ssp. planlarum GaoB3 xxiii p: 2.45967 additional omega catego ry: 1.00757 prob (additional omega category); 0.229044 log-l ikeli hood : -I R9 1.46 K: 1.64521 a:  ...  0.309511 p: 2 .70504 log-likelihood: -I X90.04 K: 1.49762 a: 0.275644 p: 2.6131 additional omega category: 1.5 prob (additional C' lIncgil category): 0 Not applicable II< log-li kel ihood: -I ORO.o tr  ...  Between the membrane and the methylation region a HAMP (histidine kinase, adenyl cyclase, methyl-accepting chemotaxis protein and phosphatase) linker is located, which propagates the signal of ligand binding  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s00253-011-3582-y">doi:10.1007/s00253-011-3582-y</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/21993479">pmid:21993479</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6diu6tiepbb3flcn7v7i6a5vnm">fatcat:6diu6tiepbb3flcn7v7i6a5vnm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20171110190230/https://core.ac.uk/download/pdf/11984980.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/2c/6c/2c6c298ef6b880ec701a8fd131d162f28eb31c15.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s00253-011-3582-y"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a>

A Close-up View of the VraSR Two-component System

Antoaneta Belcheva, Dasantila Golemi-Kotra
<span title="2008-03-07">2008</span> <i title="American Society for Biochemistry &amp; Molecular Biology (ASBMB)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/mryncoafc5cxdicldzfm4vlsze" style="color: black;">Journal of Biological Chemistry</a> </i> &nbsp;
A phosphotransfer-mediated signaling pathway composed of a histidine protein kinase, VraS, and a response regulator protein, VraR, has been linked to the coordination of this response.  ...  Our findings provide for the first time insights into the molecular basis for the proposed role of VraSR as a "sentinel" system capable of rapidly sensing cell wall peptidoglycan damage and coordinating  ...  Acknowledgment-We thank Negar Nostrati for assistance in preparation of the VraR N expression construct.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1074/jbc.m710010200">doi:10.1074/jbc.m710010200</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/18326495">pmid:18326495</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/4nvx3zf3urf4penfvf2jiux7qa">fatcat:4nvx3zf3urf4penfvf2jiux7qa</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180727030415/http://www.jbc.org/content/283/18/12354.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/a0/b1/a0b1a9aa23d6865342c6847efa6347ead7cf9b77.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1074/jbc.m710010200"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Two-Component Signal Transduction Systems ofXanthomonasspp.: A Lesson from Genomics

Wei Qian, Zhong-Ji Han, Chaozu He
<span title="">2008</span> <i title="Scientific Societies"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/dcygyjfrnrga3phn5xognbvnjm" style="color: black;">Molecular Plant-Microbe Interactions</a> </i> &nbsp;
In addition, our analysis suggests that a co-evolutionary model, rather than a selfish operon model, is the major mechanism for the maintenance and microevolution of TCSTS genes in the genomes of Xanthomonas  ...  The two-component signal transduction systems (TCSTSs), consisting of a histidine kinase sensor (HK) and a response regulator (RR), are the dominant molecular mechanisms by which prokaryotes sense and  ...  Most of these HKs are multifunctional proteins that have kinase, phosphatase, and phosphotransferase functions.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1094/mpmi-21-2-0151">doi:10.1094/mpmi-21-2-0151</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/18184059">pmid:18184059</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/mlf73by5pbh5fpki7bwgamgwse">fatcat:mlf73by5pbh5fpki7bwgamgwse</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170809015009/http://www.im.ac.cn/UserFiles/File/2008/200801-05/Molecular%20Plant-Microbe%20Interactions%2021-151-hecz.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/18/15/181581aa214a277c0d3cfb501ce521909cfa775c.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1094/mpmi-21-2-0151"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Bacterial Quorum-Sensing Network Architectures

Wai-Leung Ng, Bonnie L. Bassler
<span title="">2009</span> <i title="Annual Reviews"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/e6h4xgim2neibkbgjbnn3fz52m" style="color: black;">Annual Review of Genetics</a> </i> &nbsp;
We describe how studies of the V. harveyi and V. cholerae quorum-sensing systems have revealed some of the fundamental mechanisms underpinning the evolution of collective behaviors.  ...  Quorum sensing is a cell-cell communication process in which bacteria use the production and detection of extracellular chemicals called autoinducers to monitor cell population density.  ...  ACKNOWLEDGMENTS We thank members of the Bassler laboratory for insightful discussions and Mr. Carey Nadell for his input on evolution of group behaviors in bacteria.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1146/annurev-genet-102108-134304">doi:10.1146/annurev-genet-102108-134304</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/19686078">pmid:19686078</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4313539/">pmcid:PMC4313539</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/lkmbpmf42bc4ffgn6w7p4mrmge">fatcat:lkmbpmf42bc4ffgn6w7p4mrmge</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170809081422/http://www.its.caltech.edu/~bi1/Bi1__Micro-_to_Macro-Biology/Additional_Readings_files/Bacterial%20Quorum-Sensing%20Network%20Architectures.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/0c/e4/0ce43f9d0e502f81de8ad97bcfa9b7b26d2445d0.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1146/annurev-genet-102108-134304"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313539" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

The Agrobacterium tumefaciens CheY-like protein ClaR regulates biofilm formation

Nathan Feirer, DohHyun Kim, Jing Xu, Nico Fernandez, Christopher M. Waters, Clay Fuqua
<span title="2017-11-01">2017</span> <i title="Microbiology Society"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/fa4dlzev4nb3dnwfmkrrdfbphi" style="color: black;">Microbiology</a> </i> &nbsp;
This report of a novel CheY-type biofilm regulator in A. tumefaciens thus also adds significant details to the role of pterin-mediated signalling.  ...  of attachment can function independently from DcpA, including dampening of c-di-GMP levels.  ...  Acknowledgements We thank the MSU Mass Spectrometry Facility for assistance with the c-di-GMP measurements. Conflicts of interest The authors declare that there are no conflict sof interest.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1099/mic.0.000558">doi:10.1099/mic.0.000558</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29068284">pmid:29068284</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5845703/">pmcid:PMC5845703</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/fzooekuwuvbbdhh3trplnklgyq">fatcat:fzooekuwuvbbdhh3trplnklgyq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200208062231/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5845703&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/64/3d/643da088b94160e2d02680cba1acd6cd044f6971.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1099/mic.0.000558"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845703" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

An Overview of Two-Component Signal Transduction Systems Implicated in Extra-Intestinal Pathogenic E. coli Infections

Erin J. Breland, Allison R. Eberly, Maria Hadjifrangiskou
<span title="2017-05-09">2017</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/6thgqfebmngxzdcx4yjgtkznqa" style="color: black;">Frontiers in Cellular and Infection Microbiology</a> </i> &nbsp;
ACKNOWLEDGMENTS We thank the members of the Hadjifrangiskou lab for their help in revising this review.  ...  Many sensor histidine kinases are bi-functional, having the ability to also act as phosphatases or reverse phosphotransferases, dephosphorylating the response regulator.  ...  Histidine kinases typically function as dimeric membrane receptors and consist of a sensing domain, a kinase domain, and a catalytic domain that binds and hydrolyzes ATP.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fcimb.2017.00162">doi:10.3389/fcimb.2017.00162</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28536675">pmid:28536675</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5422438/">pmcid:PMC5422438</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/3lyhrqvk4fhfvkoy5g4dwh5cre">fatcat:3lyhrqvk4fhfvkoy5g4dwh5cre</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190307024657/http://pdfs.semanticscholar.org/d9ad/2e5a2d4d5a1afe010fae1ad91cddd0d3673c.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/d9/ad/d9ad2e5a2d4d5a1afe010fae1ad91cddd0d3673c.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fcimb.2017.00162"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422438" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Analysis of HubP-dependent cell pole protein targeting in Vibrio cholerae uncovers novel motility regulators

Ipek Altinoglu, Guillaume Abriat, Alexis Carreaux, Lucía Torres-Sánchez, Mickaël Poidevin, Petya Violinova Krasteva, Yoshiharu Yamaichi, Lotte Søgaard-Andersen
<span title="2022-01-12">2022</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/j6fzfstrmzcj3aeps7bx6tpoy4" style="color: black;">PLoS Genetics</a> </i> &nbsp;
Together, these results reveal an ever more versatile role for the landmark cell pole organizer HubP and identify novel mechanisms of motility regulation.  ...  These include a cell-wall remodeling enzyme (DacB), a likely chemotaxis sensory protein (HlyB), two presumably cytosolic proteins of unknown function (VC1210 and VC1380) and two membrane-bound proteins  ...  We are grateful for Sandra Daniel, Romain Le Bars, and Marion Decossas for their technical assistance and experiments peripheral to the project, as well as to Brittany Carroll and Jun Liu for model coordinates  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pgen.1009991">doi:10.1371/journal.pgen.1009991</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/35020734">pmid:35020734</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8789113/">pmcid:PMC8789113</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6gfbg3yiqbgkvbnedd776qllti">fatcat:6gfbg3yiqbgkvbnedd776qllti</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20220209074731/https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009991&amp;type=printable" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/2e/6d/2e6d59bc8acfd64d6a96f560346745516d84d60a.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pgen.1009991"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789113" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Overview of Mathematical Approaches Used to Model Bacterial Chemotaxis I: The Single Cell

M. J. Tindall, S. L. Porter, P. K. Maini, G. Gaglia, J. P. Armitage
<span title="2008-07-19">2008</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/zasl75vjunffjdn7osabykmsua" style="color: black;">Bulletin of Mathematical Biology</a> </i> &nbsp;
We conclude by discussing the importance of this and the future of modeling in this area.  ...  Mathematical modeling of bacterial chemotaxis systems has been influential and insightful in helping to understand experimental observations.  ...  PKM was partially supported by a Royal Society Wolfson Merit Award. The authors are particularly grateful to the referees for their comments and careful reading of the manuscript.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s11538-008-9321-6">doi:10.1007/s11538-008-9321-6</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/18642048">pmid:18642048</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/subitqdikjg7lk3yn4jvxayl3m">fatcat:subitqdikjg7lk3yn4jvxayl3m</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20171210073917/https://core.ac.uk/download/pdf/97124.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/23/65/23656033d04303d02c3236d70c207d013061055b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s11538-008-9321-6"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a>
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