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Datacenter Networks and Relevant Standards [chapter]

Daniel S. Marcon, Rodrigo R. Oliveira, Luciano P. Gaspary, Marinho P. Barcellos
2015 Cloud Services, Networking, and Management  
Overview Datacenters are the core of cloud computing, and their network is an essential component to allow distributed applications to run efficiently and predictably [17] .  ...  A Clos network [25] consists of multiple layers of switches; each switch in a layer is connected to all switches in the previous and next layers, which provides path diversity and graceful bandwidth degradation  ...  In fact, most physical data center designs are unique: hence expansions and upgrades must be custom-designed and network performance (including bisection bandwidth, endto-end latency and reliability) must  ... 
doi:10.1002/9781119042655.ch4 fatcat:ex7fwmh3fra4dg6tycdwog6dje

Expander Datacenters: From Theory to Practice [article]

Vipul Harsh, Sangeetha Abdu Jyothi, Inderdeep Singh, P. Brighten Godfrey
2018 arXiv   pre-print
Recent work has shown that expander-based data center topologies are robust and can yield superior performance over Clos topologies.  ...  In this paper, we examine if expanders can be effective for the technology and environments practical in today's data centers, including the use of traditional protocols, at both small and large scale  ...  LEGUP [15] proposed a design to build heterogeneous Clos networks for flexible expansion.  ... 
arXiv:1811.00212v1 fatcat:7g54n5yxnnbh5n7s4olh4pwzk4

Condor

Brandon Schlinker, Radhika Niranjan Mysore, Sean Smith, Jeffrey C. Mogul, Amin Vahdat, Minlan Yu, Ethan Katz-Bassett, Michael Rubin
2015 Proceedings of the 2015 ACM Conference on Special Interest Group on Data Communication - SIGCOMM '15  
We also show that Condor supports the daunting task of designing multi-phase network expansions that can be carried out on live networks.  ...  The design space for large, multipath datacenter networks is large and complex, and no one design fits all purposes.  ...  Our approach is especially valuable for designers of largescale data-center networks, because of the complexity that arises at larger scales, but it should also be useful to many organizations with medium-scale  ... 
doi:10.1145/2785956.2787476 dblp:conf/sigcomm/SchlinkerMSMVYK15 fatcat:nvvyjsvbkneljc7ue73dmqr5xq

The Emerging World of Membrane Vesicles: Functional Relevance, Theranostic Avenues and Tools for Investigating Membrane Function

Aswin T Srivatsav, Shobhna Kapoor
2021 Frontiers in Molecular Biosciences  
Finally, we discuss the use of membrane vesicles as excellent tools for investigating membrane lateral organization and protein sorting, which is otherwise challenging but extremely crucial for normal  ...  We present current limitations in this field and how the same could be addressed to propel a fundamental and technology-oriented future for extracellular membrane vesicles.  ...  We acknowledge BEI Resources, NIAID, NIH for purified mycobacterial lipids and antibodies supporting our work.  ... 
doi:10.3389/fmolb.2021.640355 pmid:33968983 pmcid:PMC8101706 fatcat:rwzfmku4xvaszkvmsskfa2afwe

History of Science and Technology

1991 Bulletin of Science, Technology & Society  
In this sense, the successful quest for efficiency drives the field.  ...  For example, Xerox had the Palo Alto Research Center (PARC) and AT&T had Bell Labs.  ...  Appendix Two Original Research Below is pseudo code for a flight search program, first in the style of structured programming and then in the style of ad hoc coding of the 1960s.  ... 
doi:10.1177/027046769101100610 fatcat:xac6li3shraexpvdhi66lwu22u

Ma [chapter]

Nicholas Arndt
2015 Encyclopedia of Astrobiology  
Mega annum; Megayear; Myr Definition Ma is a common scientific abbreviation for Megayears = 1 million (10 6 ) years derived from the Latin Mega-annum.  ...  ., the Archean eon lasted for 2,000 Myr). Ma is the most common unit of time used to describe events through most of the history of the Earth, the other planets, and meteorites.  ...  One challenge facing molecular line surveys is the efficient presentation of the data to the community.  ... 
doi:10.1007/978-3-662-44185-5_912 fatcat:v2en4jninbbbjeubtc255fdw4m

Citizen science in conservation biology : best practices in the geoweb era

Ian Parfitt
2013
In the current era of declining budgets for biodiversity research and management, volunteer citizen science is gaining recognition as an important strategy for expanding and extending the work of embattled  ...  I find that citizen science is often employed to undertake research at large spatial scales, and that often location is a key attribute of the data citizens gather; as a result, the infrastructure and  ...  associated with the CLO.  ... 
doi:10.14288/1.0073768 fatcat:ql2qyajksfdx3m5tltswo2zdsu

Tuesday, 1 September 2009

2009 European Heart Journal  
Methods: Among the 11 large-scale trials involving more than 1000 participants treated with folic acid or placebo for more than 1 year for prevention of CVD, data were available from 8 trials involving  ...  The B-Vitamin Treatment Trialists' Collaboration was set up to combine data from all randomized trials assessing the effects of lowering homocysteine levels with B-vitamins on risk of vascular and non-vascular  ...  The incidence of IE remains high and the prognosis dismal in dialysis patients, although patients selected for early valve surgery have good 1 year survival.  ... 
doi:10.1093/eurheartj/ehp415 fatcat:4jdsa3a2inbg5j3qwou5aglfcy

Analysis of Polarized Communities in Online Social Networks

Mauro Coletto
2016
Online Social Networks (OSNs), then, provide a space for user aggregation in groups, expressing opinions, accessing information, contributing to public debates, and participating in the formation of belief  ...  2:3 billion (31%) are active social media users (GlobalWeb Index data, Jan 2016).  ...  very efficient to compute.  ... 
doi:10.6092/imtlucca/e-theses/204 fatcat:os36fbvee5gkrml3m6ueznbyri

Converging Technologies for Improving Human Performance NANOTECHNOLOGY, BIOTECHNOLOGY, INFORMATION TECHNOLOGY AND COGNITIVE SCIENCE NSF/DOC-sponsored report

Mihail Roco, William Sims Bainbridge
unpublished
Nanoscopic, minimally i nvasive technology f or t he earl y dia gnosis a nd monitoring of dis ease an d targeted i ntervention will save lives in space and on Earth.  ...  Systems will be customer-centered and personalized.  ...  MAKING SENSE OF THE WORLD: CONVERGENT TECHNOLOGIES FOR ENVIRONMENTAL SCIENCE Jill Banfield, University of California, Berkeley Through t he c ombination o f ge oscience, b iology, a nd n ano-a nd i nformation  ... 
fatcat:kowkghk4xbbknmwqitcyreyxo4

The hidden order of intrinsically disordered proteins and its role in molecular recognition

Borja Mateos
2019 unpublished
For these reasons, intrinsically disordered regions are generally orchestrating signalling events in eukaryotic cells.  ...  Konrat (Vienna) for enlightening discussions on IDPs. P. Selenko, A. Nebreda and V. Dötsch for their initial support with X. laevis experiments and M. Mayzel and V. Orekhov  ...  The extremely short re ery times observed for am 1 H in a-synuclein at clos physiological condit prompted us to design 1 H N -start 13 C-detected exp ments with minimal pertu tion of the water 1 H spins  ... 
doi:10.25365/thesis.60692 fatcat:wm6padsfrjffxib55d7n4lws5e

Genetic Basis of Neuronal Subtype Differentiation in Caenorhabditis elegans

Chaogu Zheng
2017
POU-domain transcription factor UNC-86 and the LIM domain transcription factor MEC-3, the terminal selectors that activate a battery of genes (referred as TRN terminal differentiation genes) required for  ...  Meital Oren-Suissa, and the Oliver Hobert lab for the help on whole genome sequencing, the WGS data analysis, and the laser ablation experiments. We thank Dr. Michael Koelle and Dr.  ...  Yuichi Iino for sharing materials. We thank Dr. Tulle Hazelrigg for suggestions on the project. We also thank the members of the Chalfie lab for helpful discussions.  ... 
doi:10.7916/d88g8k0d fatcat:6iqphv27hvfwjgu4angqkofc7i