A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is
Purpose: The objective of this study was to investigate the bactericidal effects of high intensity focused ultrasound (HIFU) on Bacillus Calmette–Guerin (BCG, a substitute for Mycobacterium tuberculosis) in vitro and in vivo, and to explore the underlying mechanisms. Materials and methods: HIFU, at a fixed frequency of 1 MHz, was applied to both BCG culture suspensions and subcutaneous BCG abscesses in rats. Results: HIFU irradiation significantly reduced the bacterial survival rate and causeddoi:10.6084/m9.figshare.9746675.v1 fatcat:mgd7fymrkrdujpp53speisrvja
more »... emperature elevations both in vitro and in vivo. Furthermore, BCG suspensions irradiated for 15 s at 3185 and 6369 W/cm2 had increased cell wall damage, which resulted in morphological changes compared to the untreated control group. Additionally, we observed histological changes in the rat subcutaneous abscesses after HIFU ablation at 6369 W/cm2. H&E staining of infected lesions showed coagulative necrosis with central nucleus dissolution and increased infiltration of inflammatory cells, as well as nuclear pyknosis and nuclear fragmentation in the periphery. The volumes of the subcutaneous abscesses in the HIFU-treated group were significantly lower than those in the sham-treated group. Conclusion: HIFU has the therapeutic potential to treat BCG-infected tissues in rats. We theorize that a combination of mechanical, cavitation, and thermal effects most efficiently inactivate BCG bacteria via HIFU. This study is expected to provide a bio-plausible basis for a noninvasive and effective treatment for tuberculosis.
for 60 min at 4 °C. ... Then the beads were digested with 200 μl pre-heated (20 min at 50 °C) Proteinase K solution (4 mg/ml) for 40 min at 50 °C with rotation at 2 000 rpm/min. ...doi:10.1038/cr.2017.55 pmid:28418038 pmcid:PMC5594206 fatcat:hkxrmnas2fad5gbegzvhfhtbny
Undernutrition is highly prevalent in Nepal, which interferes with physical and mental development among children. It is one of the severe health problems contributing to the significant portion of the disease burden. This study aimed to explore socio-demographic and healthcare-seeking related predictors of undernutrition among children under five years old in Dang, Nepal. Methods: This was a descriptive cross-sectional study. A sample of 426 children was participated through stratifieddoi:10.33314/jnhrc.v18i3.2875 pmid:33210646 fatcat:h7q3dycstrbotled47y7wgm5j4
more »... onate random sampling to identify socio-demographics and healthcare-seeking predictors of undernutrition. Multivariable regression was applied to identify the independent predictors of undernutrition. Results: This study found that children below 24 months of age were more likely to be undernourished than children aged 24-36 months. Female children (OR=2.32, 95% CI: 1.19-4.54), illiterate or non-formally educated women (OR=4.09, 95% CI: 1.84-9.08), mother's occupation other than a housewife (OR=13.05, 95% CI: 4.19-40.68), labor work of father (OR=2.40, 95% CI: 1.04-5.57) had increased risk of undernutrition among children. Similarly, food insufficiency from their land, antenatal care visit, postnatal care visit, and delivery place were significantly associated with childhood undernutrition among children. Conclusions: The study showed that undernutrition among children is associated with age and gender of children, educational attainment of the mother, food sufficiency, health-seeking practices of the mother during pregnancy, delivery, and postnatal. Socio-demographics and health-seeking practices related predictors must be explicitly considered to address undernutrition among children under the age of five years. Keywords: Children; health care seeking; Nepal; socio-demographic factors; undernutrition.
Prime Min. and Min. of Defense and Foreign Affairs: Madhav Kumar NEPAL Home Affairs: Khadga Prasad Sharma OLI Local Dev. and Supply: Chandra Prakash MAINALI Finance: Bharat Mohan ADHIKARY Agriculture,. ... .: Man Mohan ADHIKARY Dep. ...
Prime Min. and Min. of Defense and Foreign Affairs: Madhav Kumar NEPAL Home Affairs: Khadga Prasad Sharma OLI Finance and Supply: Bharat Mohan ADHIKARY Agriculture,. ... .: Man Mohan ADHIKARY Dep. ...
Prime Min. and Min. of Defense and Foreign Affairs: Madhav Kumar NEPAL Home Affairs: Khadga Prasad Sharma OLI 160 A, June 1995 ... .: Man Mohan ADHIKARY Dep. ...
Finally, a review of Orhan Pamuk's novel Snow written by Uday Adhikari is included. ... Bam Dev Adhikari's study on Laxmi Prasad Devkota's Bapu sonnets deals with how the poet idealized Gandhian myth in these creations. ...doi:10.3126/jodem.v11i1.34798 fatcat:tvjhtvxgona5llfljax4ls7jqy
Sanjay Prasad Paudel Crises in NCP, Nepal in crises: The Iceberg Floats on the Bottom of the Sea Mediakhavar 34 mins ago Introductory Back ground Unfortunately, NCP has been divided into two main streams ... ( Sanjay Prasad Paudel: MA, M.Phil, writes in social and political issue.) ...doi:10.6084/m9.figshare.13593581.v1 fatcat:fapbzom5sjhwlbi7pa6vser7ri
(Ashraf & Tang 2017 , Kumar & Prasad 2015 , Sharma & Dubey 2005 . ... Deligiannis et al 2009 , Gonzalez-chavez et al 2015 , Goyal et al 2014 , Huagang et al 2011 , Jumat et al 2010 , Kiran & Prasad 2016 , 2017 , Kumar & Prasad 2015 , Ogunniyi 2006 , Pal et al 2013 , Pandey ...doi:10.15316/sjafs.2017.9 fatcat:hs7uvvol6rb53cimbljt7eok7i
The two groups were compared in terms of fetal outcome like: meconium passage, low birth weight, low APGAR (Appearance, Pulse, Grimace, Activity and Respiration) score at 1 and 5 min, Neonatal Intensive ... the two groups there was significant difference in terms of meconium passage (11% vs 48.9%), low birth weight (5.8% vs 18%), low APGAR (Appearance, Pulse, Grimace, Activity and Respiration) score at 1 min ... Adhikari et at.: Perinatal Outcome in Term Pregnancy with Isolated Oligohydramnios: Retrospective Observational Study ...doi:10.3126/jngmc.v19i2.42989 fatcat:u5hgc2b5rrd3boeqif6te3f2qy
It was kept at room temperature for 30 min and absorbance of the reaction mixture was measured at 415 nm with double beam UV spectrophotometer. ... of 0.5 mm methanolic solution of DPPH.The mixture was shaken vigorously and incubated for 37 min in the dark at room temperature. The absorbance was measured at 517 nm using UV spectrophotometer. ...doi:10.1016/j.ijbiomac.2016.05.058 pmid:27212219 fatcat:myjy6gcrwrhhnflhtufyekftue
Her initial blood pressure was 80/60 mm of Hg, heart rate was 98/min, respiratory rate was 20/min and temperature was 102.8°F. ... Subhash Prasad Acharya provided support and mentorship for development, writing and revision of this case report. And he was directly involved in patient's care during his stay in ICU. ...doi:10.1016/j.amsu.2020.07.027 pmid:32760582 pmcid:PMC7390825 fatcat:2awwhh4v2bbolmmhxnk4wsjnzm
Prasad, Anupama Sankaran, Gnanabalan Murugesan and Shanmughasundaram Ramanathan Impact of maternal thyroid disease on neonatal thyroid status 237 Se-Jun Park, Keun-Ho Lee, Chong-Suh Lee, Ki-Tack ... Chiesa, Federica Ricci, Lulash Nika, Paola Sciortino and Marco Spada SLC25A19 deficiency and bilateral striatal necrosis with polyneuropathy: a new case and review of the literature 261 Doris Taha, Amita Adhikari ...doi:10.1515/jpem-2021-frontmatter2 fatcat:iwfmiubq5zhjppk4io5rz7nwmq
., 1969) , ricebran (Adhikari and Adhikari, 1986), palm, coriander, carrot (Goh et al., 1982) , papaya (Prasad et al., 1987) , olive, barley, cucurbit (Schneider, 1989 ), corn, karanza, castor bean ... (Paulose et al., 1966 , cocoa (Parsons et al., 1969) , neem (Prasad et al., 1981) , sesame, khakan (Prasad et al., 1979 ), pear, quince, tobacco (Zlatanov et al., 2000 . ...doi:10.7324/japs.2016.60805 fatcat:6kq7r3yvknanxl4y6u35asaz3u
Cyanobacteria exhibited varied sensitivity to UV-B radiation (280-315 nm: 0.4 W m − 2 ) as 30 min of UV-B exposure caused 32, 88 and 95% growth yield after 10th day of treatment in N. muscorum, P. boryanum ... Photosynthetic pigment contents, whole cell oxygen yield, 14 C-fixation and PS II activity decreased with increasing doses of UV-B exposure (15 and 60 min), however, the inhibitory effect in N. muscorum ... ; Prasad et al., 2005) . ...doi:10.1016/j.sajb.2009.03.003 fatcat:fy7qdrveqfhdvcxij36yguhw3y
« Previous Showing results 1 — 15 out of 407 results