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Authors' contributions Dr Taku, Dr Miki, Dr Yasunori and Dr Kazuhiro have made substantial contribution to conception and design; Dr Taku, Dr Miki, Dr Yasunori and Dr Kazuhiro have made substantial contribution ...doi:10.1186/s12871-016-0295-x pmid:28125971 pmcid:PMC5267365 fatcat:uhryb22ypfflbhxxqk7db45vdu
Synopsis Attempts were made to prevent methylcholanthrene tumorigenesis in mice by immunization with the insoluble lipoprotein of methylcholanthrene-induced sarcomas of the same strain of mice. Swiss/Mk mice were intensively immunized with the insoluble lipoprotein fraction extracted by the Thomas method or with the supernatant fraction of isogenic methylcholanthrene-induced tumor cells, or normal cells with Freund adjuvant. As control groups, mice pretreated with Freund adjuvant alone anddoi:10.20772/cancersci1959.58.3_203 fatcat:5n236t7htbg3ri2punmzriq3da
more »... ated mice were prepared. Each mouse was injected with 0.5mg of 3methylcholanthrene*4 as a pellet or an olive oil suspension. Several series of repeated experiments always revealed the inhibitory effect of immunization with the insoluble lipoprotein fraction of a tumor on tumor occurrence. The tumor supernatant showed a slight inhibitory effect but was not so marked as the insoluble lipoprotein fraction. Tumor occurrence in groups immunized with normal insoluble lipoprotein or normal supernatant and that of adjuvant injection showed no significant difference from that in untreated group. Neither histological nor biological differences have been found among the developing tumors in the experimental groups.
Hashimoto is ohoku-ku, Yokoh 45-566-1587; e-m N. Miki is wi ohoku-ku, Y firstname.lastname@example.org H. ... H CNTs has no as been well perature T c , hi s with Maki Lab hama-shi, Kanaga mail: hashimoto@ ith Miki Labora Yokohama-shi, c.jp). ith Maki Labora Yokohama-shi, c.jp). ...doi:10.5281/zenodo.1061130 fatcat:tuinv4lg45anhnfq72jlu53aoe
Topical spray of prednisolone in aero-sol containing 0.35%prednisolone and 0.35% dextromycin sulphate was tried to a limited number of patients with dermatitis-eczema, including one case of pemphigus vulgaris and one case of Behcet syndrome. Satisfactory results were obtained especially in acute contact dermatitis and chronic eczematous dermatitis. The use of this spray seemed to be particularly recommendable for the eroded, wet, intertriginous, and/or feminine facial lesions.doi:10.11340/skinresearch1959.2.139 fatcat:feqa6ljrmbfxjaywp3p5s2rp54
, Tsujino, Maekura, Matsuki, Miki, Hashimoto, Kagawa, Kawasaki, Kuge and Kida. ... Diagnostics 11:364. doi: 10.3390/diagnostics11020364 PubMed Abstract | CrossRef Full Text | Google Scholar Miki, K., Maekura, R., Hiraga, T., Hashimoto, H., Kitada, S., Miki, M., et al. (2009). ...doi:10.3389/fphys.2021.703977 pmid:34393822 pmcid:PMC8355815 fatcat:oinoj2svm5bebidd3zgtljkoou
Kenji Miki 1,2,3 , Ryota Hashimoto 3,4,5 , Kenrin Shi 2,3,6 and Masao Yukioka 3 www.rheumatology.oxfordjournals.org Editorial Downloaded from https://academic.oup.com/rheumatology/article-abstract/ ...doi:10.1093/rheumatology/keu309 pmid:25122724 fatcat:jbqw3u7ddrgalcvgjtsctjjjt4
We present secondaly ion mass spectrometry (SIMS) study results on interfaces of LiNbO3 based optoeleclronic devices, which have been performed in order to examine the cause of device failures. The devices are widely used in current high-speed optica1 fiber communication systems. and such investigation from a materials-viewpoint is' important to improve the device quality. Especially. the device long-term stability is strongly affected by alkali-contaminants diffused into the SiO2 buffer layerdoi:10.1557/proc-654-aa3.2.1 fatcat:6crfiij6wrdszgbkfoh4l3y474
more »... f device, and here we confirmed that an adoption of common Si3N4 passivation is effective in preventing the process-induced contamination without any influence to device performance.
A 94-year-old man consulted our hospital due to a rapidly growing tumor on the left cheek. The histological diagnosis of the tumor was basal cell carcinosarcoma, which was composed of intermingled epithelial and mesenchymal components. The former was basal cell carcinoma, while the latter was spindle cell sarcoma. The tumor was completely resected with a 3-mm margin and the patient remained free of local recurrence or distinct metastasis for 2 years. We report here a case of cutaneous basaldoi:10.1159/000492525 pmid:30283313 pmcid:PMC6167722 fatcat:t6ukgdvkpjanrganoekasbp7qu
more »... carcinosarcoma and a review of the literature. Discussion CS is a biphasic neoplasm, with malignant epithelial and mesenchymal differentiation mixed widely in one lesion. The sarcomatous components has been recognized as a meta-
In cardiopulmonary exercise testing (CPET), oxygen uptake (V'O2) is calculated using the product of minute ventilation (V'E) and the difference between inspiratory and expiratory O2 concentrations (ΔFO2). However, little is known about the response of ΔFO2 to pulmonary rehabilitation (PR). The aim of the present study was (1) to investigate whether PR increases peak V'O2, based on whether ΔFO2 or V'E at peak exercise increase after PR, and (2) to investigate whether an improvement in ΔFO2doi:10.3390/jcm11040963 pmid:35207235 pmcid:PMC8878603 fatcat:6wv6ffrjnrbbfcrxu7jqtx3n7a
more »... ates with an improvement in ventilatory efficiency. Methods: A total of 38 patients with severe and very severe COPD, whose PR responses were evaluated by CPET, were retrospectively analyzed. Results: After PR, peak V'O2 was increased in 14 patients. The difference in ΔFO2 at peak exercise following PR correlated with the difference in peak V'O2 (r = 0.4884, p = 0.0019), the difference in V'E/V'CO2-nadir (r = −0.7057, p < 0.0001), and the difference in V'E–V'CO2 slope (r = −0.4578, p = 0.0039), but it did not correlate with the difference in peak V'E. Conclusions: The increased O2 extraction following PR correlated with improved exercise tolerance and ventilatory efficiency. In advanced COPD patients, a new strategy for improving O2 extraction ability might be effective in those in whom ventilatory ability can be only minimally increased.
doi:10.1183/09031936.00061806 pmid:17251234 fatcat:vskkoveknjc4fofc3e46mmw4k4
Rationale: Death following orthopedic surgery has become rare, but does occur. Acute myocardial infarction (AMI) can be a cause of such death, but diagnosis of AMI is often challenging, even by autopsy. Patient concerns: We have recently experienced 2 cases of sudden death after bone fracture surgery, in which AMI and pulmonary thromboembolism were clinically suspected as causes of death. Case 1 was a 60-year-old male with a history of diabetes mellitus who died 7 days after surgery fordoi:10.1097/md.0000000000007006 pmid:28538416 pmcid:PMC5457896 fatcat:svo5nlylljbmxhf5vj7cdvplxq
more »... dislocation fracture. Case 2 was a 75-year-old female who died several hours after surgery for proximal femur fracture. Diagnoses: At autopsy, slight myocardial change suggestive of AMI, severe coronary stenosis, and pulmonary congestion were noted in case 1. No signs for AMI were observed, but diffuse fat emboli were identified in the pulmonary vasculature in Case 2. Thus, postmortem pathological diagnosis was AMI in case 1 and it was suggestive of fat emboli in case 2. Interventions: Immunohistochemical analysis of smooth muscle markers in the coronary artery was performed in both cases. Outcomes: The positivity ratio of h-caldesmon to a-smooth muscle actin indicative of maturity of neointimal smooth muscle cells was preserved in case 2 but diminished in case 1, where coronary occlusion may have been caused via plaque rupture. Lessons: Immunostaining of smooth muscle markers in the coronary artery may serve as a supporting tool in establishing or disregarding AMI at autopsy. Abbreviations: AMI = acute myocardial infarction, CPA = cardiopulmonary arrest, LAD = left anterior descending branch, LCX = left circumflex branch, PTE = pulmonary thromboembolism, SMA = smooth muscle actin.
doi:10.1145/1276958.1277304 dblp:conf/gecco/MikiHFHS07 fatcat:3ydakdasj5htrh2z2k7jhz46dq
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