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María Heredia Mantis & Luis Gómez Canseco, coords., «Vida y escritura en el teatro de Cervantes» / Ignacio García Aguilar, Luis Gómez Canseco & Adrián J. Sáez, «El teatro de Miguel de Cervantes»
2018
Anuario Lope de Vega: Texto, Literatura, Cultura
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Por su parte, LuigiGiuliani se explaya en la lectura cervantina de las tragedias de Lupercio Leonardo
Jorge García López http://revistes.uab.cat/anuariolopedevega mo Quinientos. ...
Dos primeras que Vida y escritura / El teatro de Miguel de Cervantes 413 http://revistes.uab.cat/anuariolopedevega se arremolinan en torno a su experiencia profesional en Andalucía (1582-1587, 1587-1604 ...
doi:10.5565/rev/anuariolopedevega.285
fatcat:4ybedmyhjvfirl4synspei45xu
Extractos hidro-etanólicos de plantas comestibles como alternativa para controlar bacterias patógenas, parásitos e insectos en la industria pecuaria
2019
BIOtecnia
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En la actualidad, el uso de antibióticos para el control de infecciones es limitado, debido a la resistencia de los microorganismos a estos fármacos. ...
En la industria pecuaria es importante mantener al ganado en buen estado de salud para alcanzar niveles adecuados de producción. ...
La prueba de comparación de medias se realizó por la prueba de Tukey y Kramer a un nivel de significancia de 0.5 %. ...
doi:10.18633/biotecnia.v21i2.905
fatcat:emojipbrdbdwrawtczwwmjnd4a
Psoriasis pustulosa generalizada de von zumbusch: Reporte de un caso
2019
Pro Sciences
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Presentamos el caso de una paciente que ingresó al servicio de terapia intensiva con lesiones dérmicas características de una enfermedad cutánea neutrofílica con fallo multiorgánico que no obedece a etiología ...
La psoriasis pustulosa generalizada conocida como enfermedad de Von Zumbusch, es una enfermedad dermatológica poco frecuente de origen genético que se expresa por una respuesta inflamatoria exagerada, ...
La edad media de inicio de la psoriasis varía de un estudio a otro, pero casi el 75% de los pacientes con psoriasis tienen un inicio antes de los 40 años, y el 12% de los pacientes tienen el inicio de ...
doi:10.29018/issn.2588-1000vol3iss18.2019pp6-9
fatcat:ljoqoktiqrgrjnrgvyla4caixm
Digenic Inheritance in Cystinuria Mouse Model
2015
PLoS ONE
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Cystinuria is an aminoaciduria caused by mutations in the genes that encode the two subunits of the amino acid transport system b 0,+ , responsible for the renal reabsorption of cystine and dibasic amino acids. The clinical symptoms of cystinuria relate to nephrolithiasis, due to the precipitation of cystine in urine. Mutations in SLC3A1, which codes for the heavy subunit rBAT, cause cystinuria type A, whereas mutations in SLC7A9, which encodes the light subunit b 0,+ AT, cause cystinuria type
doi:10.1371/journal.pone.0137277
pmid:26359869
pmcid:PMC4567282
fatcat:nbxpgpt4znaazft3xbzzubipby
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... . By crossing Slc3a1 -/with Slc7a9 -/mice we generated a type AB cystinuria mouse model to test digenic inheritance of cystinuria. The 9 genotypes obtained have been analyzed at early (2-and 5-months) and late stage (8months) of the disease. Monitoring the lithiasic phenotype by X-ray, urine amino acid content analysis and protein expression studies have shown that double heterozygous mice (Slc7a9 +/-Slc3a1 +/-) present lower expression of system b 0,+ and higher hyperexcretion of cystine than single heterozygotes (Slc7a9 +/-Slc3a1 +/+ and Slc7a9 +/+ Slc3a1 +/-) and give rise to lithiasis in 4% of the mice, demonstrating that cystinuria has a digenic inheritance in this mouse model. Moreover in this study it has been demonstrated a genotype/phenotype correlation in type AB cystinuria mouse model providing new insights for further molecular and genetic studies of cystinuria patients.
Caracterización de un nuevo diseño de sensor de temperatura basado en el efecto de resonancia de plasmones
2019
Revista de Ciencias Tecnológicas
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Por lo tanto, basado en el efecto SPP, utilizando la configuración de resonancia de plasmón de la superficie de rejilla dorada, se caracteriza un nuevo diseño de sensor de temperatura. ...
En una escala macroscópica, como consecuencia de la variación de temperatura, los materiales muestran dilatación o contracción. ...
de acoplamiento de la rejilla de difracción. ...
doi:10.37636/recit.v2398105
fatcat:bjw4zxnvnzbnzfem4wvgqmjs6u
The bioenergetic signature of cancer: a marker of tumor progression
2002
Cancer Research
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Fernández (Instituto de Investigaciones Biomédicas Augusto Pi y Suñer) and M. ...
Rejas, Centro de Biología Molecular "Severo Ochoa," for contributions with the electron microscopy work. ...
Human liver and colon tissue biopsies were obtained from the Banco de Tejidos y Tumores, IDIBAPS, Hospital Clinic, Barcelona and from Red de Banco de Tumores, Centro Nacional de Investigaciones Oncológicas ...
pmid:12438266
fatcat:kammupxh4fhozdjz2peww53lni
RNA integrity as a quality indicator during the first steps of RNP purifications : a comparison of yeast lysis methods
2004
BMC Biochemistry
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The completion of several genome-sequencing projects has increased our need to assign functions to newly identified genes. The presence of a specific protein domain has been used as the determinant for suggesting a function for these new genes. In the case of proteins that are predicted to interact with mRNA, most RNAs bound by these proteins are still unknown. In yeast, several protocols for the identification of protein-protein interactions in high-throughput analyses have been developed
doi:10.1186/1471-2091-5-14
pmid:15461782
pmcid:PMC524479
fatcat:d4d7pr2vtfgx5g53g55lyxvmzm
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... g the last years leading to an increased understanding of cellular proteomics. If any of these protocols or similar approaches shall be used for the identification of mRNA-protein complexes, the integrity of mRNA is a critical factor. We compared the effect of different lysis protocols on RNA integrity. We report dramatic differences in RNA stability depending on the method used for yeast cell lysis. Glass bead milling and French Press lead to degraded mRNAs even in the presence of RNase inhibitors. Thus, they are not suitable to purify intact mRNP complexes or to identify specific mRNAs bound to proteins. We suggest a novel protocol, grinding deep-frozen cells, for the preparation of protein extracts that contain intact RNAs, as lysis method for the purification of mRNA-protein complexes from yeast cells.
Epizootic of highly pathogenic H7N3 Avian Influenza in an ecologic reserve in Mexico
[article]
2020
bioRxiv
pre-print
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Navarro-López R, Vázquez-Mendoza LF, Villarreal CL, Casaubon MT, Márquez 434 MA. ...
The Regional Zoo Miguel Álvarez del Toro (ZooMAT), is located within this natural reserve(Fig. 1). ...
doi:10.1101/2020.03.05.978502
fatcat:eadpuxczufeg3minsrbp3rtawq
Genotypic classification of patients with Wolfram syndrome: insights into the natural history of the disease and correlation with phenotype
2013
Genetics in Medicine
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This work was supported by SAF2009-12606-C02-02 from MINECO (Spain), INTRA/10/730.1 from CIBER de Enfermedades Raras (an initiative of ISCIII, Spain), and SGR 2009-1490 (Generalitat de Catalunya). ...
The median age of deceased patients (DE, n = 29) was 27 ± 11.4 years, but two peaks of higher frequency could be clearly observed-one at 24 and the other at 45 years of age. ...
DE, deceased; DI, diabetes insipidus; DM, diabetes mellitus; HD, hearing defects; ND, neurological, psychiatric, and developmental defects; OA, optic atrophy; UD, urological or renal defects; WS, Wolfram ...
doi:10.1038/gim.2012.180
pmid:23429432
fatcat:uwc2zvhvmve4rekzclmqrpmsmq
Signalling via CD70, a member of the TNF family, regulates T cell functions
2004
Journal of Leukocyte Biology
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ACKNOWLEDGMENTS Grants from Fondo de Investigaciones Sanitarias (FIS00/0181) and FEDER IFD97-2061 supported this work. P. A. and M. L-B. contributed equally. ...
Alessandro Moretta (University of Genova, Italy); TS1/16 anti-CD29, kindly provided by Francisco Sánchez-Madrid (Hospital de la Princesa, Madrid, Spain); and QA32 anti-CD70, obtained by immunizing mice ...
doi:10.1189/jlb.1003508
pmid:15226368
fatcat:lifjdvsuk5eefdxydwsvxq277y
Characterization and risk estimate of cancer in patients with primary Sjögren syndrome
2017
Journal of Hematology & Oncology
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Funding This work is supported by the Grant Fondo de Investigaciones Sanitarias (MRC, INT15/00085) and by the "CERCA Programme/Generalitat de Catalunya". ...
doi:10.1186/s13045-017-0464-5
pmid:28416003
pmcid:PMC5392920
fatcat:d637je5yyfdhtcomkae5vxtmfm
A Conserved Mechanism for Controlling the Translation of β-F1-ATPase mRNA between the Fetal Liver and Cancer Cells
2000
Journal of Biological Chemistry
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López de Heredia, C. Ugalde, M. Chamorro, and J. M. Cuezva, manuscript in preparation. ...
doi:10.1074/jbc.275.10.7430
pmid:10702318
fatcat:nx3ltt4vonc7fazf6jftm2dpia
Insights into MLC pathogenesis: GlialCAM is an MLC1 chaperone required for proper activation of volume-regulated anion currents
2013
Human Molecular Genetics
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Knockdown of MLC1 in primary astrocytes causes cell vacuolation: A MLC disease cell model
2011
Neurobiology of Disease
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Acknowledgments We thank Miguel Morales, Xavier Gasull and Soledad Alcántara for initial help with primary astrocyte cultures, Logopharm GmbH for initial proteomic studies, Elena Ambrosini for the gift ...
When the mixed glial cells reached confluence, contaminating microglia, oligodendrocytes and precursor cells were dislodged by mechanical agitation and removed as previously described (McCarthy and de ...
Moreover, MLC1 localization was not altered in a mouse model of Alexander disease (Hagemann et al., 2006) (Supplementary Figure 1A and 1B) or in a human brain from a patient with Alexander disease (de ...
doi:10.1016/j.nbd.2011.03.015
pmid:21440627
pmcid:PMC3885813
fatcat:avj264vw3zbspkaiewcmlugdoy
BootstRatio: A web-based statistical analysis of fold-change in qPCR and RT-qPCR data using resampling methods
2012
Computers in Biology and Medicine
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Nunes by MICINN and Generalitat de Catalunya, respectively. ...
Acknowledgments This work was partially supported by CIBER de Enfermedades Raras, an initiative of the ISCIII Institute of Health Research of the Spanish Governement. ...
doi:10.1016/j.compbiomed.2011.12.012
pmid:22270228
fatcat:psabee2x4rbjvciosflqjr7tei
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