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The incredible phenotypic and genetic diversity of mtD can be attributed at least in part to the RC dual genetic control (nuclear DNA (nDNA) and mitochondrial DNA (mtDNA)) and the complex interaction between ... involves a multipronged approach including clinical assessment, metabolic screening, imaging, pathological, biochemical and functional testing to guide molecular genetic analysis. ... Conflicts of Interest: The author declares no conflict of interest. ...doi:10.3390/jcm6070064 pmid:28677615 pmcid:PMC5532572 fatcat:g6b6zuxaybczpcmbpgv7siagea
Now, we are witnessing a transition from simulations of simpler membrane models to multicomponent systems, culminating in realistic models of an increasing variety of cell types and organelles. ... Cell membranes contain a large variety of lipid types and are crowded with proteins, endowing them with the plasticity needed to fulfill their key roles in cell functioning. ... al. 382 show complexation between cytochrome bc1 and cytochrome c oxidase and point toward a specific role for CL in bridging the proteins together. ...doi:10.1016/j.bpj.2017.11.2032 fatcat:opnbavtgknhqvhjfvosyawur2u
Encyclopedia of Genetics, Genomics, Proteomics and Informatics
The mitochondrial respiratory chain involves the multisubunit complexes (I) NADH-UQ oxidoreductase, (II) succinate dehydrogenase, (III) UQ-cytochrome c oxidoreductase, (IV) cytochrome c oxidase, and (V ... The outer membrane is associated with monoamine oxidase and a NADH-cytochrome c reductase. Cardiolipin, phosphatidyl inositol, and cholesterol are major compounds associated with the inner membrane. ... derived from the father and grandfather (Teuscher C et al 2006 Proc Natl Acad Sci USA 103:8024) . ...doi:10.1007/978-1-4020-6754-9_10520 fatcat:tj67vdv34vc63hlfupk6xahu24
Morphologically, the cristae structure of SSM and IFM differs, in that SSM have mostly lamelliform cristae, whereas IFM have tubular or a mixture of tubular and lamelliform cristae  . ... chamber or in separate chambers communicating through filters or diffusible membranes  . ...doi:10.1007/s00395-018-0696-8 pmid:30120595 fatcat:iev3q3qvwzfltfxm2nsreyc5ba