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Nutrition Informatics (Nutri-informatics): A call for improved and integrative standards for nutrition research

Lauren Chan, Nicole Vasilevsky, Anne Thessen, Julie McMurry, Melissa Haendel
2020 Zenodo  
While a variety of nutrition-related ontologies such as Food Ontology and the Ontology for Nutritional Studies have been initiated, they are still in development and require further attention from nutrition  ...  Approaches to formalize nutrition research language and connect standardized terminologies across biomedical fields have been initiated through the use of biomedical ontologies and computational nutrition  ...  , and nutrient therapies in the Medical Action Ontology (MAxO) have been represented, alongside a few nutrition related behaviors in the Neuro Behavior Ontology (NBO).  ... 
doi:10.5281/zenodo.4147676 fatcat:miiroccmj5gxhafvjcqrgko5jq

Semantic models for environmental exposures: Linking geo and bio via the toxicology community

Anne E Thessen, Lauren E Chan, Rebecca Boyles, Christopher J Mungall, Melissa A Haendel
2020 Zenodo  
To represent environmental exposures in the Monarch knowledge graph we created the Environmental Conditions, Treatments, and Exposures Ontology (ECTO) and proposed a model for linking environments to diseases  ...  Development of the ontology and the model was guided by biomedicine and toxicology, two user communities that have a keen interest in understanding the effect of elements of the environment on gene expression  ...  Patterns and typing • Chemicals • Medical actions • Environmental processes • Environmental materials • Behaviors • Change • Organisms • Geographic feature • Occupations and hobbies • Exposure  ... 
doi:10.5281/zenodo.3723249 fatcat:id7uyqfjlbgh5m7pbpcvlqc3ai

The landscape of nutri-informatics: a review of current resources and challenges for integrative nutrition research

Lauren Chan, Nicole Vasilevsky, Anne Thessen, Julie McMurry, Melissa Haendel
2021 Database: The Journal of Biological Databases and Curation  
Finally, we will conclude with a call to action to create and follow community standards regarding standardization of language, documentation specifications and requirements for data reuse.  ...  In particular, we will focus on the application of biomedical ontologies and their potential to improve the standardization and interoperability of nutrition terminologies and relationships between nutrition  ...  and nutrient therapies in the Medical Action Ontology (MAxO) have been represented, alongside a few nutrition-related behaviors in the Neuro Behavior Ontology (NBO).  ... 
doi:10.1093/database/baab003 pmid:33494105 pmcid:PMC7833928 fatcat:l6jywwjkgncvtb6kxoou2c5swy

The Environmental Conditions, Treatments, and Exposures Ontology (ECTO): Connecting Toxicology and Exposure to Human Health and Beyond

Lauren Chan, Anne Thessen, William D. Duncan, Nicolas Matentzoglu, Charles Schmitt, Cynthia Grondin, Nicole Vasilevsky, Julie McMurry, Peter Robinson, Christopher J. Mungall, Melissa Haendel
2022 Zenodo  
Introductory manuscript to present the Environmental Conditions, Treatments, and Exposures Ontology (ECTO).  ...  Cancer Institute Thesaurus; MAxO, Medical Actions Ontology; HPO, Human Phenotype Ontology; Mondo, Mondo Disease Ontology; GO, Gene Ontology.  ...  In addition to the listed ontologies, ECTO also imports Gene Ontology, Information Artifact Ontology (IAO), Medical Actions Ontology (MAxO), Neuro Behavior Ontology (NBO), NanoParticle Ontology (NPO),  ... 
doi:10.5281/zenodo.6360645 fatcat:hfy2eldfhvclrkdjhzkr3bkqnm

DDIEM: drug database for inborn errors of metabolism

Marwa Abdelhakim, Eunice McMurray, Ali Raza Syed, Senay Kafkas, Allan Anthony Kamau, Paul N Schofield, Robert Hoehndorf
2020 Orphanet Journal of Rare Diseases  
Therapeutic approaches, including both successful and ineffective treatments, were manually classified by their mechanisms of action using a new ontology.  ...  We present a manually curated, ontologically formalized knowledgebase of drugs, therapeutic procedures, and mitigated phenotypes.  ...  the Medical Action Ontology [29] which is currently under development and will broadly characterize therapeutic procedures.  ... 
doi:10.1186/s13023-020-01428-2 pmid:32527280 pmcid:PMC7291537 fatcat:tbecpsjs75fohn6yfwizsafmpa

DDIEM: Drug Database for Inborn Errors of Metabolism [article]

Marwa Abdelhakim, Eunice McMurray, Ali Raza Syed, Senay Kafkas, Allan Anthony Kamau, Paul N Schofield, Robert Hoehndorf
2020 biorxiv/medrxiv   pre-print
Therapeutic approaches, including both successful and ineffective treatments, were manually classified by their mechanisms of action using a new ontology.  ...  Conclusions: We present a manually curated, ontologically formalized knowledgebase of drugs, therapeutic procedures, and mitigated phenotypes.  ...  of Diseases IEM: Inborn errors of metabolism IRDiRC: International Rare Diseases Research Consortium KEGG: Kyoto Encyclopedia of Genes and Genomes MAxO: Medical Action Ontology MPO: Mammalian Phenotype  ... 
doi:10.1101/2020.01.08.897223 fatcat:oftqmw5eerfcfkuwpnpyzgkkme

Providing Comorbid Decision Support via the Integration of Clinical Practice Guidelines at Execution-Time by Leveraging Medical Linked Open Datasets

William Van Woensel, Samina Abidi, Borna Jafarpour, Syed Sibte Raza Abidi
2019 Studies in Health Technology and Informatics  
We propose an execution-time approach to safely and efficiently cope with comorbid conditions, leveraging knowledge from medical Linked Open Datasets to aid during CIG integration.  ...  (DrOn) 3 and Bio2RDF DrugBank ontology 4 .  ...  To support the identification of adverse interactions, we leverage various Linked Open Datasets (LOD), including the SNOMED CT ontology 1 , the Drug-Drug Interactions Ontology (DINTO) 2 , the Drug Ontology  ... 
doi:10.3233/shti190345 pmid:31438046 fatcat:jpdxvm4zqrb65d36yfwtlpzlru

The Environmental Conditions, Treatments, and Exposures Ontology (ECTO): Connecting Toxicology and Exposure to Human Health and Beyond

Lauren Chan, Anne Thessen, William D. Duncan, Nicolas Matentzoglu, Charles Schmitt, Cynthia Grondin, Nicole Vasilevsky, Julie McMurry, Peter Robinson, Christopher J. Mungall, Melissa Haendel
2022 Zenodo  
Introductory manuscript to present the Environmental Conditions, Treatments, and Exposures Ontology (ECTO).  ...  Cancer Institute Thesaurus; MAxO, Medical Actions Ontology; HPO, Human Phenotype Ontology; Mondo, Mondo Disease Ontology; GO, Gene Ontology.  ...  Identification of stimuli in environmental substances is critical for disease prevention and management of adverse health outcomes, as well as to identify and evaluate mechanisms of action to develop clinical  ... 
doi:10.5281/zenodo.6360321 fatcat:vaf2h4l72jffbd4aosodgz5uje

Conditioned Medium From Human Amniotic Mesenchymal Stromal Cells Limits Infarct Size and Enhances Angiogenesis

Patrizia Danieli, Giuseppe Malpasso, Maria Chiara Ciuffreda, Elisabetta Cervio, Laura Calvillo, Francesco Copes, Federica Pisano, Manuela Mura, Lennaert Kleijn, Rudolf A. de Boer, Gianluca Viarengo, Vittorio Rosti (+3 others)
2015 Stem Cells Translational Medicine  
Gene Ontology (GO) functional annotation analysis was performed on this latter group of 131 genes.  ...  The oxygen level in the chamber was ,0.5% (oxygen analyzer MAXO 2 ; Maxtec, Salt Lake City, UT, http://www. maxtec.com).  ... 
doi:10.5966/sctm.2014-0253 pmid:25824141 pmcid:PMC4414224 fatcat:3hku7qyqljfcxlkalsjr3e4kza

"I Felt All the Pangs of Exile": Trauma and the Fight for Human Rights in the Memoirs of Nabokov, Soyinka, and Danticat

Lauren Marlatt
2019
Danticat's tone is influential in her story when she documents her uncle's treatment with medical personnel.  ...  Danticat must use medical records as her only source of information for the decline and death of her uncle.  ... 
doi:10.57709/14311203 fatcat:thvg3u5qvrg25ph4ueg5sqzfki

Inform atica

Pavol Navrat, Cene Bavec, Matjaž Gams
2001 unpublished
Figure 1 . 1 Sample of a domain knovvledge model (ontology).  ...  Figure 4 : 4 Autonomous actions contained vvithin Internet Banking transaction Figure 6 : 6 Autonomous actions contained vvithin the celi phone, PDA scenario FoUovving is an explanation of these actions  ... 
fatcat:77obuhlo2bazdjm74cuxiprf5a

UNPACKING PEACEBUILDING ¿ ASSESSING POLITICAL LEGITIMACY AMIDST INTERNATIONAL INTERVENTION IN HAITI IN COMPARATIVE PERSPECTIVE [article]

MARIANA DOS SANTOS PARRA
2020
Maxo was a social and environmental activist, and one among the many disillusioned with Aristide and the Lavalas movement.  ...  normalcy that common people try to maintain in their daily lives, worsening the precarious conditions prevalent, turning even harder the access to basic goods such as fuel, food and medicine, as well as medical  ...  The role of the international community/ foreign action in the country  I'd like to know your opinion about the role of the international community in Haiti.  ... 
doi:10.13130/dos-santos-parra-mariana_phd2020-03-20 fatcat:cunirlcy5ra2bbckt3wdjclbl4

Trans Tessituras: Confounding, Unbearable, and Black Transgender Voices in Luso-Afro-Brazilian Popular Music

Daniel Da Silva
2019
Yet, maxo, an intentional misspelling of the Portuguese word macho, means male and masculine.  ...  Notably, it is through medicalization that many trans people have been able to seek protections, medical assistance, and gender reassignment surgery if needed, as well as hormones or other medical strategies  ... 
doi:10.7916/d8-xkxt-eg63 fatcat:ihrwzrfjqrf5pjecun552afoja

Computational systems biology methods for functional classification of membrane proteins and modeling of quorum sensing in Pseudomonas aeruginosa [article]

Nadine Sarah Schaadt, Universität Des Saarlandes, Universität Des Saarlandes
2013
parameters and κ o , δ maxo , and ψ o the previous ones.  ...  Since naturally occurring mutants often show a decreased fitness compared to the wild type, the parameters δ max , κ, and ψ may be also influenced, maxo + e if δ maxo + e m , δ maxm , and ψ m are the mutated  ... 
doi:10.22028/d291-22896 fatcat:nlef6wh5tvew7fn5skpjkm6rai

Respectus Philologicus, 2009 Nr. 15 (20)

Gabija Bankauskaitė
2009 Respectus Philologicus  
Somers and Gibson (1994, pp. 37-99) distinguish between ontological, public, conceptual and meta narratives.  ...  Humanitarinių mokslų atstovui ši sąvoka visų pirma asocijuojasi su 1947 metų Maxo Horkheimerio ir Theodoro Adorno esė "Kultūros industrija. Apšvieta kaip masių apgaulė".  ... 
doi:10.15388/respectus.2009.20 fatcat:zxcuyetvufe6bnhh7hpze5iqhm