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Messages from forgotten friends: classic cell adhesion molecules inhibit regeneration too
<span title="2016-07-12">2016</span>
<i title="EMBO">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/xcjlfiweh5bfpiome6ieuwel2a" style="color: black;">EMBO Journal</a>
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Beyond degree and betweenness centrality: Alternative topological measures to predict viral targets
<span title="2018-05-24">2018</span>
<i title="Public Library of Science (PLoS)">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a>
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OPEN ACCESS Citation: Devkota P, Danzi MC, Wuchty S (2018) Beyond degree and betweenness centrality: Alternative topological measures to predict viral targets. PLoS ONE 13(5): e0197595. https://doi. ...
In particular, we defined betweenness centrality c B of a node v as c B = ∑ s6 ¼t6 ¼v2V σ st (v)/σ st , where σ st was the number of shortest paths between proteins s and t. ...
(C) As a corollary, we utilized all five topological measures to predict viral targets using a random forest. ...
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Large scale in silico characterization of repeat expansion variation in human genomes
<span title="2020-09-08">2020</span>
<i title="Springer Science and Business Media LLC">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/a577b42d4nfhddl7kurxnuyzem" style="color: black;">Scientific Data</a>
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(c) Number of TRs as a function of sample size. (d) Frequency plot of the number of times a TR is observed in the cohort. ...
(c) Number of TRs as a function of sample size. (d) Frequency plot of the number of times a TR is observed in the cohort. ...
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Identification of miRNAs involved in DRG neurite outgrowth and their putative targets
<span title="">2017</span>
<i title="Wiley">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/kn6dhptylrb77b5atyiom5ysjm" style="color: black;">FEBS Letters</a>
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The neurons were immunostained for βIII tubulin (B, E, H) and automatically traced (C, F, I). ...
RNA isolation was performed as described in Danzi et al [39] . Briefly, neurons were collected in 50 μl of extraction buffer from the Arcturus® PicoPure® RNA Isolation Kit (Life Technologies, USA). ...
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A novel mutation in VCP causes Charcot–Marie–Tooth Type 2 disease
<span title="2014-08-14">2014</span>
<i title="Oxford University Press (OUP)">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/3yly6om4ynhcta4fdjenhrdk5y" style="color: black;">Brain</a>
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This analysis resulted in a log of odds (LOD) score of 2.107 for the c.553C 4 T VCP mutation in this family. ...
(C) Close-up view of the N-D1 interface where all known mutations reside (in blue) and the position of E185 (white). ...
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Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth
<span title="2015-06-24">2015</span>
<i title="American Chemical Society (ACS)">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/yltjzcy7vfg7bbsek3hqc7eane" style="color: black;">ACS Chemical Biology</a>
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Samples were immediately placed in a heat block and kept at 95°C for 10 min. ...
At four weeks after injury, we found significantly more sprouting in mice treated with RO480500-002 than in vehicletreated controls (Fig. 4 c-g). ...
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PP4-dependent HDAC3 dephosphorylation discriminates between axonal regeneration and regenerative failure
[article]
<span title="2018-10-18">2018</span>
<i title="Cold Spring Harbor Laboratory">
bioRxiv
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<span class="release-stage" >pre-print</span>
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C. ...
C. ...
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Identification of genome-wide targets of Olig2 in the adult mouse spinal cord using ChIP-Seq
<span title="2017-10-19">2017</span>
<i title="Public Library of Science (PLoS)">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a>
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OPEN ACCESS Citation: Darr AJ, Danzi MC, Brady L, Emig-Agius D, Hackett A, Golshani R, et al. (2017) Identification of genome-wide targets of Olig2 in the adult mouse spinal cord using ChIP-Seq. ...
Validation: Matt C. Danzi, Pantelis Tsoulfas. Visualization: Matt C. Danzi, Pantelis Tsoulfas. Writing -original draft: Andrew J. Darr, Matt C. Danzi, Pantelis Tsoulfas. ...
Darr, Matt C. Danzi, Lee Brady, Dorothea Emig-Agius, Amber Hackett, Roozbeh Golshani, Nikita Warner, Jae Lee, Vance P. Lemmon, Pantelis Tsoulfas. 26. ...
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Opposing Functions of Microglial and Macrophagic TNFR2 in the Pathogenesis of Experimental Autoimmune Encephalomyelitis
<span title="">2017</span>
<i title="Elsevier BV">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/5ihveavyobfs3mlzee7cjt7mfe" style="color: black;">Cell Reports</a>
</i>
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(C and D) Quantification of Olig2 + CC1 + cells (C) and Olig2 + PDGFRa + cells (D) in the spinal cord. n = 3-5/ group; *p % 0.05, **p % 0.01, Student's t test. ...
., 2010) , and its downregulation is indicative of increased BBB permeability, which (C, F, and I) Quantification of cytokine expression in CD4 (C, F) and CD8 (I) T cells from spinal cord and spleen; n ...
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sj-pdf-1-jbx-10.1177_24725552211026270 – Supplemental material for Phenotypic Screening Following Transcriptomic Deconvolution to Identify Transcription Factors Mediating Axon Growth Induced by a Kinase Inhibitor
<span title="2021-07-04">2021</span>
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Lowell, Nicholas O'Neill, Matt C. Danzi, Hassan Al-Ali, John L. Bixby and Vance P. Lemmon in SLAS Discovery ...
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Genetic compensation in a stable slc25a46 mutant zebrafish: A case for using F0 CRISPR mutagenesis to study phenotypes caused by inherited disease
<span title="2020-03-24">2020</span>
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The PCR conditions consisted of an initial denaturation step at 95˚C for 10 min followed by 40 cycles at 95˚C for 15 s (denaturation) and 60˚C for 1 min (elongation). ...
Tissues were permeabilized with cold (-20˚C) acetone for 9 minutes. ...
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Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling
<span title="2020-12-21">2020</span>
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The thermal cycle profile consisted of 1 cycle (5 min at 94°C; 2 min at 52°C; 7 min at 72°C) and a further 40 cycles (1 min at 94°C; 1 min 54°C; 1 min 72°C). ...
The thermal cycle profile consisted of 45 cycles composed of 4 stages (5 min at 95°C, 20 s at 95°C, 20 s at 56°C, 20 s at 72°C) and a final dissociation stage. ...
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Enrichment of SARM1 alleles encoding variants with constitutively hyperactive NADase in patients with ALS and other motor nerve disorders
<span title="2021-11-19">2021</span>
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R484C -rs1555585809 28385090 G>A 28385095 C>T 0 0 1 1 A488E rs782228906 28385108 C>A 0.00012 2 Y501H rs144613221 28385146 T>C 0.0029 32 13 T502P rs782421919 28385149 A>C 0.000074 1 V518L rs782106973 28385197 ...
C>A 0.000015 1 R244S - 28381462 C>A 0 1 249-252 - 28381475_86 del 0 1 ARM A250T A275V rs1555585243 rs376587698 28381480 G>A 28381556 C>T 0 0.000029 1 1 A301S rs782606059 28381633 G>T 0.00012 3 R310H rs369186722 ...
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Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models
<span title="2019-04-10">2019</span>
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The authors are grateful to O Bildstein, O Egesi, G Edomwonyi, and C Strittmatter (UMR 7364) for their assistance in animal care. ...
at 60°C, 30 s at 72°C) × 12 cycles; 5 min at 72°C] to create the cDNA library. ...
The ligated products were enriched by PCR [2 min at 98°C; (30 s at 98°C, 30 s at 65°C, 60 s at 72°C) × 14 cycles; 4 min at 72°C] and cleaned-up using Agencourt AMPure XP beads. ...
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Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos
<span title="2021-12-23">2021</span>
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Analysis of the mutation spectrum shows that most SNVs detected were C > A and C > T changes (Figure 1D ). ...
The residual mutations observed in the Rad18 C28F mutant include C > T transitions and C > A transversions. ...
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