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Messages from forgotten friends: classic cell adhesion molecules inhibit regeneration too

Matt C Danzi, Vance P Lemmon
<span title="2016-07-12">2016</span> <i title="EMBO"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/xcjlfiweh5bfpiome6ieuwel2a" style="color: black;">EMBO Journal</a> </i> &nbsp;
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.15252/embj.201694938">doi:10.15252/embj.201694938</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27406713">pmid:27406713</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5010051/">pmcid:PMC5010051</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/fyh2lbrnenbvjfpgzxmzx5qxj4">fatcat:fyh2lbrnenbvjfpgzxmzx5qxj4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190227115406/http://pdfs.semanticscholar.org/7fd5/9acd4d5702d9bbaa36b87dd162fd4fdd88c5.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/7f/d5/7fd59acd4d5702d9bbaa36b87dd162fd4fdd88c5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.15252/embj.201694938"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010051" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Beyond degree and betweenness centrality: Alternative topological measures to predict viral targets

Prajwal Devkota, Matt C. Danzi, Stefan Wuchty, Lars Kaderali
<span title="2018-05-24">2018</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a> </i> &nbsp;
OPEN ACCESS Citation: Devkota P, Danzi MC, Wuchty S (2018) Beyond degree and betweenness centrality: Alternative topological measures to predict viral targets. PLoS ONE 13(5): e0197595. https://doi.  ...  In particular, we defined betweenness centrality c B of a node v as c B = ∑ s6 ¼t6 ¼v2V σ st (v)/σ st , where σ st was the number of shortest paths between proteins s and t.  ...  (C) As a corollary, we utilized all five topological measures to predict viral targets using a random forest.  ... 
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Large scale in silico characterization of repeat expansion variation in human genomes

Sarah Fazal, Matt C Danzi, Vivian P Cintra, Dana M Bis-Brewer, Egor Dolzhenko, Michael A Eberle, Stephan Zuchner
<span title="2020-09-08">2020</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/a577b42d4nfhddl7kurxnuyzem" style="color: black;">Scientific Data</a> </i> &nbsp;
(c) Number of TRs as a function of sample size. (d) Frequency plot of the number of times a TR is observed in the cohort.  ...  (c) Number of TRs as a function of sample size. (d) Frequency plot of the number of times a TR is observed in the cohort.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41597-020-00633-9">doi:10.1038/s41597-020-00633-9</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/32901039">pmid:32901039</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7479135/">pmcid:PMC7479135</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ewfmhosh6vhbll4uqyntji3st4">fatcat:ewfmhosh6vhbll4uqyntji3st4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20201108034801/https://www.nature.com/articles/s41597-020-00633-9.pdf?error=cookies_not_supported&amp;code=5edfe9f9-d73d-4b91-82f8-f298c802baac" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/e9/d0/e9d0ff7fdc929dc73070741da2347e29d1229d01.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41597-020-00633-9"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479135" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Identification of miRNAs involved in DRG neurite outgrowth and their putative targets

Dario Motti, Jessica K. Lerch, Matt C. Danzi, Jared H. Gans, Frank Kuo, Tatiana I. Slepak, John L. Bixby, Vance P. Lemmon
<span title="">2017</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/kn6dhptylrb77b5atyiom5ysjm" style="color: black;">FEBS Letters</a> </i> &nbsp;
The neurons were immunostained for βIII tubulin (B, E, H) and automatically traced (C, F, I).  ...  RNA isolation was performed as described in Danzi et al [39] . Briefly, neurons were collected in 50 μl of extraction buffer from the Arcturus® PicoPure® RNA Isolation Kit (Life Technologies, USA).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/1873-3468.12718">doi:10.1002/1873-3468.12718</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28626869">pmid:28626869</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5864114/">pmcid:PMC5864114</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/cmd53mlytfav7b4k62yxqqcgqi">fatcat:cmd53mlytfav7b4k62yxqqcgqi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200211083142/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5864114&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5c/78/5c78681395a44d36053bd02cae05f03d8112ffb1.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/1873-3468.12718"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> wiley.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864114" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

A novel mutation in VCP causes Charcot–Marie–Tooth Type 2 disease

Michael A. Gonzalez, Shawna M. Feely, Fiorella Speziani, Alleene V. Strickland, Matt Danzi, Chelsea Bacon, Youjin Lee, Tsui-Fen Chou, Susan H. Blanton, Conrad C. Weihl, Stephan Zuchner, Michael E. Shy
<span title="2014-08-14">2014</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/3yly6om4ynhcta4fdjenhrdk5y" style="color: black;">Brain</a> </i> &nbsp;
This analysis resulted in a log of odds (LOD) score of 2.107 for the c.553C 4 T VCP mutation in this family.  ...  (C) Close-up view of the N-D1 interface where all known mutations reside (in blue) and the position of E185 (white).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/brain/awu224">doi:10.1093/brain/awu224</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25125609">pmid:25125609</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4208462/">pmcid:PMC4208462</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/fb7oedncdzfybghawxe4s2jjgy">fatcat:fb7oedncdzfybghawxe4s2jjgy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200208223148/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4208462&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/2f/64/2f641dc3b242c5387451f952981e6f06cef6fc1c.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/brain/awu224"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> oup.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208462" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth

Hassan Al-Ali, Do-Hun Lee, Matt C. Danzi, Houssam Nassif, Prson Gautam, Krister Wennerberg, Bill Zuercher, David H. Drewry, Jae K. Lee, Vance P. Lemmon, John L. Bixby
<span title="2015-06-24">2015</span> <i title="American Chemical Society (ACS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/yltjzcy7vfg7bbsek3hqc7eane" style="color: black;">ACS Chemical Biology</a> </i> &nbsp;
Samples were immediately placed in a heat block and kept at 95°C for 10 min.  ...  At four weeks after injury, we found significantly more sprouting in mice treated with RO480500-002 than in vehicletreated controls (Fig. 4 c-g).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1021/acschembio.5b00289">doi:10.1021/acschembio.5b00289</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26056718">pmid:26056718</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4899818/">pmcid:PMC4899818</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/cffs7txjy5c6ff5ck5vbmlcu6a">fatcat:cffs7txjy5c6ff5ck5vbmlcu6a</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200207195101/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4899818&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/79/f1/79f1123a20bac6826fa7cd173c00bd2d8fc201a9.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1021/acschembio.5b00289"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> acs.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899818" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

PP4-dependent HDAC3 dephosphorylation discriminates between axonal regeneration and regenerative failure [article]

Arnau Hervera, Luming Zhou, Ilaria Palmisano, Eilidh McLachlan, Guiping Kong, Thomas Haynes Hutson, Matt C Danzi, Vance P Lemmon, John L Bixby, Andreu Matamoros-Angles, Kirsi Forsberg, Francesco De Virgiliis (+6 others)
<span title="2018-10-18">2018</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
C.  ...  C.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/446963">doi:10.1101/446963</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/pe3yvvth45eprjgjcdyzb7yxiu">fatcat:pe3yvvth45eprjgjcdyzb7yxiu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200325061258/https://www.biorxiv.org/content/biorxiv/early/2018/10/18/446963.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/23/a7/23a7472cfdc678dbccfe33247d9033e26994ac13.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/446963"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Identification of genome-wide targets of Olig2 in the adult mouse spinal cord using ChIP-Seq

Andrew J. Darr, Matt C. Danzi, Lee Brady, Dorothea Emig-Agius, Amber Hackett, Roozbeh Golshani, Nikita Warner, Jae Lee, Vance P. Lemmon, Pantelis Tsoulfas, Fernando de Castro
<span title="2017-10-19">2017</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a> </i> &nbsp;
OPEN ACCESS Citation: Darr AJ, Danzi MC, Brady L, Emig-Agius D, Hackett A, Golshani R, et al. (2017) Identification of genome-wide targets of Olig2 in the adult mouse spinal cord using ChIP-Seq.  ...  Validation: Matt C. Danzi, Pantelis Tsoulfas. Visualization: Matt C. Danzi, Pantelis Tsoulfas. Writing -original draft: Andrew J. Darr, Matt C. Danzi, Pantelis Tsoulfas.  ...  Darr, Matt C. Danzi, Lee Brady, Dorothea Emig-Agius, Amber Hackett, Roozbeh Golshani, Nikita Warner, Jae Lee, Vance P. Lemmon, Pantelis Tsoulfas. 26.  ... 
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Opposing Functions of Microglial and Macrophagic TNFR2 in the Pathogenesis of Experimental Autoimmune Encephalomyelitis

Han Gao, Matt C. Danzi, Claire S. Choi, Mehran Taherian, Camilla Dalby-Hansen, Ditte G. Ellman, Pernille M. Madsen, John L. Bixby, Vance P. Lemmon, Kate L. Lambertsen, Roberta Brambilla
<span title="">2017</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/5ihveavyobfs3mlzee7cjt7mfe" style="color: black;">Cell Reports</a> </i> &nbsp;
(C and D) Quantification of Olig2 + CC1 + cells (C) and Olig2 + PDGFRa + cells (D) in the spinal cord. n = 3-5/ group; *p % 0.05, **p % 0.01, Student's t test.  ...  ., 2010) , and its downregulation is indicative of increased BBB permeability, which (C, F, and I) Quantification of cytokine expression in CD4 (C, F) and CD8 (I) T cells from spinal cord and spleen; n  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.celrep.2016.11.083">doi:10.1016/j.celrep.2016.11.083</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28052249">pmid:28052249</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5218601/">pmcid:PMC5218601</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/fncru4tgcnddxdtkfjo4sfna6e">fatcat:fncru4tgcnddxdtkfjo4sfna6e</a> </span>
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sj-pdf-1-jbx-10.1177_24725552211026270 – Supplemental material for Phenotypic Screening Following Transcriptomic Deconvolution to Identify Transcription Factors Mediating Axon Growth Induced by a Kinase Inhibitor

Jeffrey A. Lowell, Nicholas O'Neill, Matt C. Danzi, Hassan Al-Ali, John L. Bixby, Vance P. Lemmon
<span title="2021-07-04">2021</span> <i title="SAGE Journals"> Figshare </i> &nbsp;
Lowell, Nicholas O'Neill, Matt C. Danzi, Hassan Al-Ali, John L. Bixby and Vance P. Lemmon in SLAS Discovery  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.25384/sage.14905649.v1">doi:10.25384/sage.14905649.v1</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ja4xeeqvx5e4zkvzs6zoy7rxty">fatcat:ja4xeeqvx5e4zkvzs6zoy7rxty</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210708133724/https://s3-eu-west-1.amazonaws.com/pstorage-sage-1076303800/28704467/sjpdf1jbx10.1177_24725552211026270.pdf?X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Expires=10&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Signature=5506571a57a0f560297548000994e0031d5d6f927030f49307e7e505a7dfa794&amp;X-Amz-Date=20210708T133723Z&amp;X-Amz-Credential=AKIAIFC63XER7EYBKGZQ/20210708/eu-west-1/s3/aws4_request" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/27/f7/27f7ecfda31ee885f52b5b155467520484af4119.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.25384/sage.14905649.v1"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Genetic compensation in a stable slc25a46 mutant zebrafish: A case for using F0 CRISPR mutagenesis to study phenotypes caused by inherited disease

Elena Buglo, Evan Sarmiento, Nicole Belliard Martuscelli, David W Sant, Matt C Danzi, Alexander J Abrams, Julia E Dallman, Stephan Züchner
<span title="2020-03-24">2020</span> <i title="Public Library of Science"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a> </i> &nbsp;
The PCR conditions consisted of an initial denaturation step at 95˚C for 10 min followed by 40 cycles at 95˚C for 15 s (denaturation) and 60˚C for 1 min (elongation).  ...  Tissues were permeabilized with cold (-20˚C) acetone for 9 minutes.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0230566">doi:10.1371/journal.pone.0230566</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/32208444">pmid:32208444</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7092968/">pmcid:PMC7092968</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6skgdcjegbffzel6eli2jawy7a">fatcat:6skgdcjegbffzel6eli2jawy7a</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200326065515/https://journals.plos.org/plosone/article/file?id=10.1371%2Fjournal.pone.0230566&amp;type=printable" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/96/3b/963b09b2d35389c3e0d5bce04463f91754169097.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0230566"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092968" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling

Francesco De Virgiliis, Thomas H. Hutson, Ilaria Palmisano, Sarah Amachree, Jian Miao, Luming Zhou, Rositsa Todorova, Richard Thompson, Matt C. Danzi, Vance P. Lemmon, John L. Bixby, Ilka Wittig (+2 others)
<span title="2020-12-21">2020</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/a4wan6l5o5dfzn767kyz7jqevi" style="color: black;">Nature Communications</a> </i> &nbsp;
The thermal cycle profile consisted of 1 cycle (5 min at 94°C; 2 min at 52°C; 7 min at 72°C) and a further 40 cycles (1 min at 94°C; 1 min 54°C; 1 min 72°C).  ...  The thermal cycle profile consisted of 45 cycles composed of 4 stages (5 min at 95°C, 20 s at 95°C, 20 s at 56°C, 20 s at 72°C) and a final dissociation stage.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41467-020-20179-z">doi:10.1038/s41467-020-20179-z</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33349630">pmid:33349630</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/cprvykm2abhu7ixo6camwcx7ay">fatcat:cprvykm2abhu7ixo6camwcx7ay</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210429095551/https://www.nature.com/articles/s41467-020-20179-z.pdf?error=cookies_not_supported&amp;code=86ca5b32-e9a1-4538-b8c6-449ba7686772" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ef/e1/efe127dfb10a794ecf2a52d9242951c34cbe212c.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41467-020-20179-z"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> nature.com </button> </a>

Enrichment of SARM1 alleles encoding variants with constitutively hyperactive NADase in patients with ALS and other motor nerve disorders

Jonathan Gilley, Oscar Jackson, Menelaos Pipis, Mehrdad A Estiar, Ammar Al-Chalabi, Matt C Danzi, Kristel R van Eijk, Stephen A Goutman, Matthew B Harms, Henry Houlden, Alfredo Iacoangeli, Julia Kaye (+11 others)
<span title="2021-11-19">2021</span> <i title="eLife Sciences Publications, Ltd"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/en4qj5ijrbf5djxx7p5zzpjyoq" style="color: black;">eLife</a> </i> &nbsp;
R484C -rs1555585809 28385090 G>A 28385095 C>T 0 0 1 1 A488E rs782228906 28385108 C>A 0.00012 2 Y501H rs144613221 28385146 T>C 0.0029 32 13 T502P rs782421919 28385149 A>C 0.000074 1 V518L rs782106973 28385197  ...  C>A 0.000015 1 R244S - 28381462 C>A 0 1 249-252 - 28381475_86 del 0 1 ARM A250T A275V rs1555585243 rs376587698 28381480 G>A 28381556 C>T 0 0.000029 1 1 A301S rs782606059 28381633 G>T 0.00012 3 R310H rs369186722  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.7554/elife.70905">doi:10.7554/elife.70905</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34796871">pmid:34796871</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8735862/">pmcid:PMC8735862</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ffshf4lzxzf67gwt3lx3fzjrvu">fatcat:ffshf4lzxzf67gwt3lx3fzjrvu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20211201095551/https://elifesciences.org/download/aHR0cHM6Ly9jZG4uZWxpZmVzY2llbmNlcy5vcmcvYXJ0aWNsZXMvNzA5MDUvZWxpZmUtNzA5MDUtdjIucGRmP2Nhbm9uaWNhbFVyaT1odHRwczovL2VsaWZlc2NpZW5jZXMub3JnL2FydGljbGVzLzcwOTA1/elife-70905-v2.pdf?_hash=jDEr9y%2BHWewy22qHBAlRZq01m9qCozmWGEqdFOcS4es%3D" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/2e/23/2e23380b7790a8ab46d544e3d50cb0efc5648f75.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.7554/elife.70905"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elifesciences.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735862" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models

Thomas H. Hutson, Claudia Kathe, Ilaria Palmisano, Kay Bartholdi, Arnau Hervera, Francesco De Virgiliis, Eilidh McLachlan, Luming Zhou, Guiping Kong, Quentin Barraud, Matt C. Danzi, Alejandro Medrano-Fernandez (+12 others)
<span title="2019-04-10">2019</span> <i title="American Association for the Advancement of Science (AAAS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/yfp7fpewebcjxcnf3x5jsya7hi" style="color: black;">Science Translational Medicine</a> </i> &nbsp;
The authors are grateful to O Bildstein, O Egesi, G Edomwonyi, and C Strittmatter (UMR 7364) for their assistance in animal care.  ...  at 60°C, 30 s at 72°C) × 12 cycles; 5 min at 72°C] to create the cDNA library.  ...  The ligated products were enriched by PCR [2 min at 98°C; (30 s at 98°C, 30 s at 65°C, 60 s at 72°C) × 14 cycles; 4 min at 72°C] and cleaned-up using Agencourt AMPure XP beads.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1126/scitranslmed.aaw2064">doi:10.1126/scitranslmed.aaw2064</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30971452">pmid:30971452</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/v5gh336edzf4jprjfruytklexm">fatcat:v5gh336edzf4jprjfruytklexm</a> </span>
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Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos

Elena Lo Furno, Isabelle Busseau, Antoine Aze, Claudio Lorenzi, Cima Saghira, Matt C Danzi, Stephan Zuchner, Domenico Maiorano
<span title="2021-12-23">2021</span>
Analysis of the mutation spectrum shows that most SNVs detected were C > A and C > T changes (Figure 1D ).  ...  The residual mutations observed in the Rad18 C28F mutant include C > T transitions and C > A transversions.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/nar/gkab1223">doi:10.1093/nar/gkab1223</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34939656">pmid:34939656</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8789082/">pmcid:PMC8789082</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/t7hr23zcyrhlvdm3hxzxdwjeyq">fatcat:t7hr23zcyrhlvdm3hxzxdwjeyq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20220105112928/https://watermark.silverchair.com/gkab1223.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAtkwggLVBgkqhkiG9w0BBwagggLGMIICwgIBADCCArsGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMlbAxk_bUZX6-382qAgEQgIICjDP8m_I-HdFojgbMQUxgcAD0xpzJPVLLHK1hS0mnJ5s4Sf7nNUAnFLdkCL17AolASQWZZDTRCkhnmhfKnwSGRBqZh-0tMIOYoTZD2Zm3rFRaAq2Hyqe_2Xzt7sbmQOlQ2c99i-qtuokzZ1X8D0RloPtHUjChx81lIHFihpMex2O_F46QlCJSwkMKun3a318AwYIfr-YkFbRjv8keyS8tsGhS7dx76Zkii6LtWEBa45Q2XBU-pWYbrDc_mcwkuMOOnrL278i27Ba7l1iViPaqbe8R97JBADFNv4zpHBujcHB-O5S7VffpsW0XtqEMb1YRw2pdGplurHJ29GDIxc5YEn4e7C_NlS5EC7aHjyBsQ1tUe8EEfRiJP9MLjXh7vLleRNPt9X1KtyZ6LP01exNnGOeK0css56Q7s4wyruuGPJvAvl9xKRSVVNVt9tzB2Y-41oGCvNwiQ-aNryuj8NkeJvdllixpCNz7PuCgWC8qVvZqIHlu2D7vg9bBiU9LQQZbTK0iVwbdeBFnUhWwVAJJOjGVeHuo0UZxDWBF2j5lrga4FhxAjXp4Fq72TxiZJyqaY20sztFN4fU7XcJgQHYaKV7MvY2gGoO5x18szwf_4Q-66ntB6L6vg2E7wc3RWOrhgnKWiUd4-7nak7mrEJiX1TXqkDFgf5barAsp1LtNeNpn4jSo347BZ4DCW1glHoAY3L_WK7gBlUzF4oWy4zwp-5Q6AI5JOIn7AobRLe9Q52HoedYy80mP6ohF7EZo2E_xUj4cwLdP8M8Xn0rdJJk8KVVC_sQsikQQhTJ0e00FzlSYcttciDxVNXMycB43pr8wjPhKewFK_l43mU7XGPHkR63GyS29t6tqwyZA0fI" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f4/e2/f4e2a4fc205a0cef6a2b8a70f1e483caaf195cf0.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/nar/gkab1223"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789082" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>
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