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Surgical Technique and Safety of TaTME for Rectal Cancer Toru Miyake 1) , Tomoharu Shimizu 2) , Tomoyuki Ueki 1) , Masatsugu Kojima 1) and Masaji Tani 1) 1) Shiga University of Medical Science, Department ...doi:10.3862/jcoloproctology.75.232 fatcat:am7573yebbcehlylltwynklzfq
This report concerns a 79-year-old woman with coexisting anaplastic thyroid carcinoma (ATC) and Graves' disease (GD). The patient was referred to our clinic because of palpitation and a palpable mass on the left side of her neck. Thyroid function tests showed hyperthyroidism with elevated thyroid-stimulating antibodies. Ultrasonography of the thyroid demonstrated an adenomatous nodule-like marcated nodule (27.6 × 26.5 × 36.4 mm) with cystic degeneration inside the left lobe. 123 I thyroiddoi:10.1507/endocrj.52.551 pmid:16284432 fatcat:szc6neombbdflmcnyhbia3toh4
more »... graphic imaging showed a cold area corresponding to the nodule with continuous uptake in the remaining thyroid tissue despite suppressed TSH levels. These findings led to a diagnosis of GD. On the other hand, the thyroid nodule could not be definitely diagnosed even after fine needle aspiration biopsy (FNAB) which produced findings suggestive of both papillary thyroid carcinoma and ATC. Open biopsy of the nodule showed an ATC. Regional lymph node metastases as well as multiple lung metastases, which could not be found at the initial visit, had been already developed by that time. Our case is pathophysiologically interesting because it suggests that GD or thyroidstimulating antibodies (TSAb) may stimulate malignant transformation of differentiated carcinoma. It is also clinically important because it indicates that all thyroid nodules, particularly palpable cold nodules, associated with GD require careful management to detect malignancy because they are at higher risk of harboring malignancy.
Kojima, MD, PhD; Daisuke Fukamachi, MD, PhD; Yasuo Okumura, MD, PhD IMAGES IN CARDIOVASCULAR MEDICINE Advance Publication ... Utility of Coronary Computed Tomography Angiography in Acute Coronary Syndrome Associated With Infectious Endocarditis Masatsugu Miyagawa, MD; Nobuhiro Murata, MD, PhD; Katsunori Fukumoto, MD; Keisuke ...doi:10.1253/circj.cj-22-0199 pmid:35660702 fatcat:fqughvhtnneabm4wrpvduiknle
Perforated Appendiceal Diverticulitis Diagnosed Preoperatively; Report of a Case Masatsugu Kojima 1) , Hiroyuki Ohta 2) , Hiroya Akabori 2) , Yumi Zen 2) and Eiji Mekata 2) and clearly apparent muscular ...doi:10.4030/jjcs.44.1073 fatcat:th5wvd23nbfspcn5nttrmsnlze
Doboku Gakkai Ronbunshuu A
and Masatsugu NAGAI The weathering steel has a unique property of preventing rust by rust, and using unpainted weathering steel is important to reduce the life cycle cost of infrastructure. ... 135, pp.267-268, 2004.9. 16) : 2 , Vol. 54A, pp.590-598, 2008.3. 17) , , : ESTIMATION OF AIRBORNE SALT BEHAVIOR AROUND THE BRIDGE SECTION BY NUMERICAL SIMULATION Eiji IWASAKI, Syun ITOH, Yasuhiro KOJIMA ...doi:10.2208/jsceja.66.752 fatcat:lrzlj6k6efcnfmqwcpgloodrwm
We describe a rare case of cervical esophageal adenocarcinoma originating from the esophageal gland. A 63-year-old man underwent endoscopic screening during a medical checkup, during which a type 2 tumor was incidentally detected in the cervical esophagus, which was confirmed as adenocarcinoma on biopsy. Endoscopic ultrasonography indicated that the tumor had invaded the muscularis propria layer. Computed tomography and 18 F-fluorodeoxyglucose positron emission tomography imaging revealeddoi:10.4030/jjcs.39.187 fatcat:limzlb7eaff57p5uvipsmopfni
more »... r lymphadenopathy nor distant metastasis. He was clinically diagnosed with T2N0M0, Stage Ⅱ disease. He preoperatively received 2 courses of chemotherapy consisting of cisplatin (90mg/m 2 ) on day 1 and 5-fluorouracil (900mg/m 2 ) on days 1-5. Esophagectomy with lymph node dissection was performed. Histopathological diagnosis showed well-differentiated tubular adenocarcinoma that probably originated from the ducts of the esophageal glands. The final diagnosis was T1b-N0M0, Stage I disease. The postoperative course was uneventful. He was healthy without any recurrence 27 months after the surgery.
【執筆者】 Hoshikawa M, Uchida S, Ganeko M, Sumitomo J, Totoki M, Kojima T, Nakamura Y, Kawahara T. ...doi:10.1080/17461391.2012.681805 pmid:24444208 fatcat:3nittwuyuzbz3ee5pld7vyskba
Hiroya Iida, Hiromitsu Maehira, Haruki Mori, Katsushi Takebayashi, Masatsugu Kojima, Sachiko Kaida, Tomoyuki Ueki, Toru Miyake, and Masaji Tani performed data collection. ...doi:10.1159/000525280 pmid:35636396 fatcat:avfdlwo62fd2fo3jhqs5s3yl6y
Word count: 4075 words Masatsugu Hamaji and Fumitsugu Kojima contributed equally to this work. ...doi:10.1093/ejcts/ezu277 pmid:25015950 fatcat:a4c5lvag6jabrfsxcei7ul6ueq
Hiroya Iida, Hiromitsu Maehira, Takeru Maekawa, Haruki Mori, Nobuhito Nitta, Katsushi Takebayashi, Masatsugu Kojima, Mika Kurihara, Shigeki Bamba, Masaya Sasaki, and Masaji Tani performed data collection ...doi:10.1159/000525551 pmid:35709689 fatcat:3aknxcvrgjgnxefhyhgn2gjwqq
OBJECTIVES: The optimal material for anterior chest wall reconstruction following chest wall resection remains controversial. The aim of this experimental study was to evaluate short-term, morphological and histological outcomes of anterior chest wall reconstruction with a rigid and bioabsorbable material in a canine model. METHODS: Twenty adult beagle dogs underwent anterior chest wall resection. In the experimental group (n = 10), the anterior chest wall was reconstructed with a rigid anddoi:10.1093/icvts/ivu416 pmid:25505306 fatcat:rwz6565jizfh5n6hr63id4kmti
more »... bsorbable material composed of poly-L-lactide acid matrix (60 wt%) and uncalcined and unsintered hydroxyapatite particles (40 wt%), whereas in the control group it was (n = 10) reconstructed with dual polypropylene mesh sheets. Short-term complication rates were compared with a χ 2 test. Postoperative sternal deviations were evaluated with sternal alignment angles using computed tomography and multiplanar reconstruction and were compared with Mann-Whitney U-test immediately after reconstruction, and at 1, 3, 6, 9 and 12 months postoperatively. Histological findings of the regenerated chest wall tissue were obtained after staining with haematoxylin and eosin and Elastica van Gieson (EVG) and compared at 3, 6, 9 and 12 months. RESULTS: There was not a significant difference in the short-term postoperative complication rate (P = 0.53) and the complication rate was 20% (wound infection, n = 1 and lethal mediastinitis, n = 1) in the control group and 10% (wound infection, n = 1) in the experimental group. The postoperative sternal deviation was significantly less remarkable at 1 month (123.3 ± 32.2°vs 159.4 ± 19.7°, P = 0.027), 3 months (109.8 ± 34.7°vs 150.9 ± 34.2°, P = 0.039) and 12 months (61 ± 15.6°vs 170.3 ± 6.6°, P = 0.046) in the experimental group than in the control group, whereas no significant difference was noted immediately after reconstruction (165.7 ± 6.4°vs 168.4 ± 9.1°, P = 0.50). Histological findings showed dense connective tissue in the regenerated chest wall in both groups and showed chondroblasts in the regenerated chest wall tissue at 3 and 6 months only in the experimental group. CONCLUSIONS: Our results suggest that anterior chest wall reconstruction with a rigid and bioabsorbable material is feasible and may be a valuable alternative to reconstruction with a non-rigid and non-absorbable material.
This study investigated energy metabolism and its association with inflammatory cytokines and appetite- regulating hormones in patients with gastrointestinal cancer. Subjects were inpatients scheduled to undergo therapeutic intervention for diagnosed gastrointestinal cancer. Nutritional status on admission was assessed based on anthropometric measurements, nutrition screening results, food intake rate (energy intake/energy provided in hospital food), and biochemical test results. Fat-free massdoi:10.3892/ol.2020.11662 pmid:32724390 pmcid:PMC7377097 fatcat:554jrja5xna6vbajskjjea7y5m
more »... FFM) was measured using the bioelectrical impedance analysis. Resting energy expenditure (REE) and respiratory quotient were measured with indirect calorimetry, and basal energy expenditure (BEE) was calculated using the Harris-Benedict equation. A total 51 patients with gastrointestinal cancer were enrolled (17 with esophageal cancer, 15 with gastric cancer, and 19 with colorectal cancer); 16 had stage I disease, 11 had stage II, 13 had stage III, and 11 had stage IV. The levels of inflammatory cytokines such as interleukin (IL)-6 and tumor necrosis factor (TNF)-α increased significantly with cancer stage progression (P<0.001; Jonckheere-Terpstra trend test). The REE/body weight and the REE/FFM tended to increase with cancer stage progression (P=0.064 and P=0.053, respectively; Jonckheere-Terpstra trend test). FFM showed a significant negative correlation with the level of TNF-α (P=0.008; Spearman's correlation coefficient). Also, food intake rate showed a significant negative correlation with levels of IL-6 and TNF-α (P<0.001). The level of active ghrelin was positively correlated with that of IL-6 and energy metabolism (P=0.004 and 0.016, respectively) and negatively correlated with food intake rate (P=0.035), which suggests a state of ghrelin resistance. In conclusion, this study confirmed increases in the levels of inflammatory cytokines with the progression of gastrointestinal cancer and suggested the possible association of such increases with decreased FFM and the increased energy metabolism. However, the increased levels of active ghrelin failed to compensate for cachexia in cancer patients.
Kojima (Inoue Hospital) and the outstanding secretarial work of C. Yokogawa. ...doi:10.1507/endocrj.k07e-138 pmid:18560201 fatcat:d5erdxc7lbd6pm4r7ftk7obn3e
Annual Meeting of the Geological Society of Japan
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