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Viral Infection in Esophageal, Gastric, and Colorectal Cancer

Takeshi Yamashina, Masaaki Shimatani, Masahiro Takeo, Kotaro Sasaki, Masahiro Orino, Natsuko Saito, Hironao Matsumoto, Takeshi Kasai, Masataka Kano, Shunsuke Horitani, Kimi Sumimoto, Toshiyuki Mitsuyama (+3 others)
2022 Healthcare  
The human gastrointestinal tract, which constitutes the digestive system, contains a large number of virus particles that maintain organizational homeostasis and health. Conversely, viral pathogens have also attracted attention for their involvement in the pathogenesis of certain cancers, including gastrointestinal cancers. To aid prevention and treatment of these cancers, the relevance of gastrointestinal viral factors as potential risk factors needs to be carefully investigated. This review
more » ... mmarizes and discusses the available literature on the relationship between the development of esophageal, gastric, and colorectal cancers and their corresponding viruses. This review reveals that research on the association between colorectal cancer and viruses, in particular, is still in its infancy compared to the association between HPV and esophageal cancer and between EBV and gastric cancer.
doi:10.3390/healthcare10091626 pmid:36141238 pmcid:PMC9498567 fatcat:jlzc6ezoircd5amfk6222w2qoq

Beam Welding
II 溶接・接合及び関連機器 2. ビーム溶接

Junji KANO, Seigo Hiramoto, Masahiro HANAI
*,Hiramoto Seigo** and HANAI Masahiro* 原稿受付 平成24年4月12日 * 正 員 三菱電機㈱ Member, Mitsubishi Electric Corporation ** 正 員 多田電機㈱ Member, Tada Electric CO.,LTD である. スラブ型高輝度 CO 2  ... 
doi:10.2207/jjws.81.384 fatcat:qs7iig4qr5bijbvyr5sud4r4xm

Hormonal changes in major depressive disorder

Toshinori Kitamura, Shojiro Kano, Satoru Shima, Masahiro Asai
1989 The Keio Journal of Medicine  
The dexamethasone suppression test (DST) was performed in 38 patients satisfying the Research Diagnostic Criteria (RDC) for cortisol, human growth hormone (hGH), prolactin, triiodothyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH) were determined at 4:00 p.m. before the administra tion of dexamethasone, whereas cortisol, hGH and TSH were determined at 4:00 p.m. the day after. Among hormonal variables, only cortisol index (the ratio of the pre-DST cortisol to the post-DST
more » ... ol) was barely useful for discriminating depression. The cortisol index was also correlated with RDC incapacitating sub category and with symptoms of affect such as depressed mood and psychic anxiety.
doi:10.2302/kjm.38.40 fatcat:xbo27ervubevtfdlhbgy75mri4

Selection of Tumor models

Hiroki Takashima, Yoshikatsu Koga, Ryo Tsumura, Hirobumi Fuchigami, Yasuhiro Matsumura, Masahiro Yasunaga, Hiroyoshi Y. Tanaka, Tsuyoshi Kurihara, Mitsunobu R. Kano
2020 Drug Delivery System  
Kano *4,5) *4) Department of Pharmaceutical Biomedicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University *5) Department of Pharmaceutical Biomedicine,  ... 
doi:10.2745/dds.35.443 fatcat:mxavbao2xvdvbfmpu6lz3pv3te

Chemical Equilibrium from the Viewpoint of Mixing Entropy and Some Comments on Equilibrium Constants

Masahiro YAMAMOTO, Kenji KANO
2022 Electrochemistry (Tokyo. 1999)  
Chemical reaction equilibrium was often introduced based on the kinetic assumption called the mass action law. In this paper, problems in the kinetic concept are pointed out and several equilibrium constants are derived on the concept of thermodynamic balance using chemical potential. Points to note in the pressure dependence of several equilibrium constants are emphasized. An important relationship between the reaction quotient and the entropy of mixing and the importance of sigmoidal
more » ... istics of equilibrium are comprehensively introduced. Comments on steady-state current-potential curves in reversible multiple electron transfer reactions are also detailed.
doi:10.5796/electrochemistry.22-66098 fatcat:vuwxnrr5vrhdlp6gge74vl42nq

Reciprocal Sum Expression for Steady-state Kinetics. —Enzyme Reactions and Voltammetry—

Yuko YOKOYAMA, Masahiro YAMAMOTO, Kohei MIYAZAKI, Takeshi ABE, Kenji KANO
2022 Electrochemistry (Tokyo. 1999)  
Steady-state experiments are often conducted to understand complicated cases in chemistry, since the kinetics does not have a time valuable and allows simple modeling of the reactions. The reciprocal of the overall rate of sequential steady-state reactions is often given in the reciprocal sum formula: sum of the reciprocals of the rates of the hypothetical rate-limiting processes at the individual stages. In this paper, the reciprocal sum relationship is generalized for sequential multi-step
more » ... ady-state reactions, and the importance and usefulness of the concept is shown by applying it to describe several typical steady-state systems in enzyme reactions and voltammetry using rotating disk-and ultramicroelectrodes.
doi:10.5796/electrochemistry.22-66044 fatcat:4pky2rk6bjal3ca7ixonjyrqgu

A Retrospective Study of Emergency Tracheotomy

Masahiro Suzuki, Makoto Kano, Hiroshi Ogawa, Koichi Omori
2003 Koutou (THE LARYNX JAPAN)  
Emergency tracheotomies were performed in 22 cases because of dyspnea due to upper airway stenosis. In 15 of those cases, tracheotomies were first tried and successfully performed. With 7 other cases, tracheal intubasions were done prior to their tracheotomies, however, in 2 cases with deep neck abscess, tracheal intubation was impossible because of severe laryngeal edemas. In one case, a percutaneous cricothyroid puncture was successfully performed. We understood that performing a percutaneous
more » ... cricothyroid puncture was necessary in some cases. Training in various types of airway maintenance techniques and accurately choosing from among them is required for emergent treatment of airway obstruction.
doi:10.5426/larynx1989.15.2_114 fatcat:g3vs5ygxn5btrmhyr4udk4whke

Schematic Feasibility Study of Bio-CCS Technology

Atsuko Tanaka, Yasuhide Sakamoto, Daisuke Mayumi, Yuki Kano, Haruyuki Higashino, Masahiro Suzumura, Masayuki Sagisaka, Yuji Nishi, Shinsuke Nakao
2014 Energy Procedia  
Among in-situ microbes within depleted oil-gas reservoir, there are special species those produce much more methane gas in CO 2 rich environment than in CO 2 poor environment. CO 2 acts as a catalyst in the reaction. If we maintain preferable conditions for methanogenesis archaea during geological CCS, we will be able to abate greenhouse gas emission and produce natural gas as one of natural energy resources at the same time. We named the technological concept as 'Bio-CCS'. In Bio-CCS, CO 2
more » ... be injected from a well for two purposes: to abate greenhouse gas emission and to cultivate methanogenic geo-microbes. CH 4 gas will be produced later using other wells. The procedure is similar to the Enhanced Oil/Gas Recovery (EOR/EGR) operation, but in Bio-CCS, the target is generation and production of methane out of depleted oil/gas reservoir during CO 2 abatement. We are evaluating the basic practicability of Bio-CCS that cultivate methanogenic geo-microbes within depleted oil/gas reservoirs for geological CCS, and produce methane gas as fuel resources on the course of CO 2 abatement for GHG control. While biologists are identifying the most effective cultivating conditions for methanogenic archaea, geologists, environmental scientists and system scientists are evaluating feasibilities of the technology concept. In this paper, we will introduce methodologies and interim results of our feasibility study on Bio-CCS.
doi:10.1016/j.egypro.2014.11.843 fatcat:2r2wcjoxnfhfbczrubj7fa7evy

モデル予測制御-II : 線形モデル予測制御
Model Predictive Control-II : Linear Model Predictive Control

Manabu KANO, Masahiro OHSHIMA
2002 Systems, Control and Information  
doi:10.11509/isciesci.46.7_418 fatcat:kyddb22yivadfgku6kyxfzptha

Characteristics of fast mediated bioelectrocatalytic reaction near microelectrodes

Yuki Kitazumi, Tatsuo Noda, Osamu Shirai, Masahiro Yamamoto, Kenji Kano
2014 Physical Chemistry, Chemical Physics - PCCP  
The ideal combination of mediated bioelectrocatalytic reaction and nonlinear diffusion near a microdisc electrode is studied.
doi:10.1039/c4cp00141a pmid:24691414 fatcat:ltrxe6bxzbgbxet3ymfaunftxa

Study of ultrasonic mass survey with special reference to intensive examination

Kenji YAMAO, Kose SEGAWA, Saburo NAKAZAWA, Yasuo NAITO, Eizo KIMOTO, Kazuo INUI, Yoshiki HAYASHI, Junichi KANO, Masahiro YAMADA, Masahiro MITAKE, Hidemi ZENDA
1987 Journal of Gastroenterological Mass Survey  
doi:10.11404/jsgcs1982.1987.77_71 fatcat:uvxpylvrhbfw3jl264ixpc3kge

Multirate Multivariable Model Predictive Control Design

Masahiro Ohshima, Manabu Kano, Iori Hashimoto, Hiromu Ohno
1994 Kagaku kogaku rombunshu  
doi:10.1252/kakoronbunshu.20.240 fatcat:2knyccxeyfeprb27x7nak4uiei

Visualisation of the T cell differentiation programme by Canonical Correspondence Analysis of transcriptomes

Masahiro Ono, Reiko J Tanaka, Manabu Kano
2014 BMC Genomics  
Currently, in the era of post-genomics, immunology is facing a challenging problem to translate mutant phenotypes into gene functions based on high-throughput data, while taking into account the classifications and functions of immune cells, which requires new methods. Results: Here we propose a novel application of a multidimensional analysis, Canonical Correspondence Analysis (CCA), to reveal the molecular characteristics of undefined cells in terms of cellular differentiation programmes by
more » ... alysing two transcriptomic datasets. Using two independent datasets, whether RNA-seq or microarray data, CCA successfully visualised the cross-level relationships between genes, cells, and differentiation programmes, and thereby identified the immunological features of mutant cells (Gata3-KO T cells and Stat3-KO T cells) in a data-oriented manner. With a new concept, differentiation variable, CCA provides an automatic classification of cell samples, which had a high sensitivity and a comparable performance to other classification methods. In addition, we elaborate how CCA results can be interpreted, and reveal the features of CCA in comparison with other visualisation techniques. Conclusions: CCA is a visualisation tool with a classification ability to reveal the cross-level relationships of genes, cells and differentiation programmes. This can be used for characterising the functional defect of cells of interest (e.g. mutant cells) in the context of cellular differentiation. The proposed approach fits with common hypothesis-oriented studies in immunology, and can be used for a wide range of molecular and genomic studies on cellular differentiation mechanisms.
doi:10.1186/1471-2164-15-1028 pmid:25428805 pmcid:PMC4258272 fatcat:fsyvuw2ajfgazdjjymqtryth5e

Aktina Vision: Full-parallax three-dimensional display with 100 million light rays

Hayato Watanabe, Naoto Okaichi, Takuya Omura, Masanori Kano, Hisayuki Sasaki, Masahiro Kawakita
2019 Scientific Reports  
Photo credits: Masanori Kano. Scientific RepoRtS | (2019) 9:17688 | .  ...  Photo credits: Masanori Kano and Hayato Watanabe. Figure 2 . 2 3D screen. (a), Configuration of the 3D screen. (b), Enlarged image of the surface of the 3D screen.  ... 
doi:10.1038/s41598-019-54243-6 pmid:31776428 pmcid:PMC6881296 fatcat:2rbecm2x4zgulgkvwiki3mjlt4

Study of the classification of mucin-producing cystic tumor of the pancreas

Saburo NAKAZAWA, Kenji YAMAO, Masahiro YAMADA, Yasuo NAITO, Eizou KIMOTO, Kazuo INUI, Yoshiki HAYASHI, Junichi KANO, Masahiro MITAKE, Sadao KOZUKA
1988 Nippon Shokakibyo Gakkai Zasshi  
胆 と膵 1981Kenji YAMAO, Masahiro YAMADA, Yasuo NAITO, Eizou KIMOTO, Kazuo INUI, Yoshiki HAYASHI, Junichi KANO, Masahiro MITAKE and Sadao KOZUKA2) 1) Second Department of Internal Medicine, Nagoya University  ... 
doi:10.11405/nisshoshi1964.85.924 fatcat:nx6zyewnkrandj2belcyjmpqmm
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