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Adaptive Learning Systems; Personalization; Optimization; Gravitational Search Algorithm

Maryam Amoozegar
2014 Iranian Journal of Information Processing & Management  
Amoozegar 1 MSc.  ...  و‬ ‫ﺑﺮﺗﺮ‬ ‫ﺟﺮم‬ ‫اﺛﺮ‬ ‫ﻣﻘﺪار‬ ‫ﺑﺎﺷﺪ،‬ ‫ﺟﻤﻌﻴﺖ‬ ‫ﮔﺬار‬ ‫ﺑﻪ‬ ‫ﺗﻌﺮﻳـﻒ‬ ‫زﻣـﺎن‬ ‫ﺑـﺎ‬ ‫ﻣﺘﻐﻴـﺮ‬ ‫ﺻـﻮرت‬ ‫ﺟﺪول‬ Optimization of Personalized Content Selection and Succession in Adaptive Learning Systems Maryam  ... 
doaj:ea86c73186514b1981274fca9aa198ca fatcat:uvufeqmskzfqrpik2vxijuvd3i

Systematics of haloarchaea and biotechnological potential of their hydrolytic enzymes

Mohammad Ali Amoozegar, Maryam Siroosi, Siavash Atashgahi, Hauke Smidt, Antonio Ventosa
2017 Microbiology  
Halophilic archaea, also referred to as haloarchaea, dominate hypersaline environments. To survive under such extreme conditions, haloarchaea and their enzymes have evolved to function optimally in environments with high salt concentrations and, sometimes, with extreme pH and temperatures. These features make haloarchaea attractive sources of a wide variety of biotechnological products, such as hydrolytic enzymes, with numerous potential applications in biotechnology. The unique trait of
more » ... haeal enzymes, haloenzymes, to sustain activity under hypersaline conditions has extended the range of already-available biocatalysts and industrial processes in which high salt concentrations inhibit the activity of regular enzymes. In addition to their halostable properties, haloenzymes can also withstand other conditions such as extreme pH and temperature. In spite of these benefits, the industrial potential of these natural catalysts remains largely unexplored, with only a few characterized extracellular hydrolases. Because of the applied impact of haloarchaea and their specific ability to live in the presence of high salt concentrations, studies on their systematics have intensified in recent years, identifying many new genera and species. This review summarizes the current status of the haloarchaeal genera and species, and discusses the properties of haloenzymes and their potential industrial applications. Halomarina Halorubellus Haloarchaeobius Halarchaeum Halalkalicoccus Haladaptatus Halorussus Halobacterium Halococcus Haloarculaceae Halapricum Halorientalis Halorhabdus Halomicrobium Halomicroarcula Halosimplex Haloarcula Natronomonas Halosarcina Uncategorized haloarchaea Fig. 1. Classification of haloarchaea from phylum to genus. Haladaptatus paucihalophilus (isolated from a low-salt spring, USA) is the type species of the genus Haladaptatus. This haloarchaeon needs 3.1 M NaCl, pH 6.5 and a temperature of 30 C for optimum growth. The cells are non-motile and coccus-shaped [21]. Hap. litoreus (isolated from a solar saltern, China) [22], Hap. pallidirubidus (isolated from saline soil, China) [23] and Hap. cibarius (isolated from fermented food, Republic of Korea) [24] are other species of the genus Haladaptatus. There are three species within the genus Halalkalicoccus, including Hac. jeotgali (isolated from fermented food, Republic of Korea) [25], Hac. paucihalophilus (isolated from saline soil, China) [26] and Hac. tibetensis (isolated from a saline lake, China) [27]. The latter is the type species of Halalkalicoccus and requires 3.4 M NaCl, 40 C and pH 9.5-10 for maximum growth. The cells are non-motile and coccus-shaped. Halarchaeum acidiphilum (isolated from solar salt, Australia) [28] is the type species of the genus Halarchaeum. The cells of the strain are non-motile, pleomorphic and grow optimally at 37 C, pH 4.4-4.5 and 3.6-4.1 M NaCl. Hla. rubridurum (isolated from solar salt, Philippines) [29], Hla. salinum (isolated from commercial salt, Indonesia) [30], Hla. solikamskense (isolated from the foamy products of flotation enrichment of potassium minerals, Russia) [31] and Hla. nitratireducens (isolated from commercial salt, Japan) [32] are other members of this genus. Haloarchaeobius amylolyticus (isolated from a solar saltern, China) [33], Hab. salinus (isolated from a salt lake, China) [34], Hab. litoreus (isolated from a solar saltern, China) [35], Hab. baliensis (isolated from a solar saltern, Indonesia) [36] and Hab. iranensis (isolated from a saline playa, Iran) [37] are the currently known species of the genus Haloarchaeobius. The latter is the type species of the genus and needs 3.5 M NaCl, 40 C and pH 7.5 for maximum growth. Halorubellus litoreus and Hrb. salinus were isolated from a marine solar saltern in China [38]. Hrb. litoreus is the type species of the genus Halorubellus and requires pH 7, 3.1 M NaCl and 37 C for maximum growth. The only known member of the genus Halomarina is Hmr. oriensis (isolated from a seawater aquarium, Japan) [39]. The strain requires 2.7 M NaCl, pH 7-8 and 37 C for optimum growth. Natronoarchaeum mannanilyticum (isolated from commercial salt, Japan) [40] is the type species of the genus Natronoarchaeum. It grows optimally at pH 8-9, 37 C and in the presence of 4-4.5 M NaCl. Nac. philippinense (isolated from commercial salt) [41] and Nac. rubrum (isolated from a solar saltern, China) [42] are other species of this genus. Halovenus aranensis (isolated from a hypersaline playa, Iran) [43], Hvn. rubra (isolated from brown alga Laminaria, China) [44] and Hvn. salina (isolated from a saltern, Spain) [45] are members of the genus Halovenus. Hvn. aranensis is the type species of this genus and grows optimally at pH 7.5, 4 M NaCl and 40 C. Natronomonas gomsonensis (isolated from saltern sediment, Republic of Korea) [46], Nmn. moolapensis (isolated from a solar saltern crystallizer, Australia) [47] and Nmn. pharaonis (isolated from alkaline lake brine, Egypt) [48] are members of the genus Natronomonas. Nmn. pharaonis is the type species of the genus, and grows optimally at 45 C, pH 8.5 and 3.4 M NaCl. Salarchaeum japonicum (isolated from commercial salt, Japan) is the only member of the genus Salarchaeum. The strain requires pH 5.2-6.3, 40 C and 2.5-3 M NaCl for maximum growth. The cells are motile and rod-shaped [49] . Salinarubrum litoreum (isolated from solar salterns, China) is the only member of the genus Salinarubrum. The optimal growth conditions for this species are pH 7, 37 C and 2.6 M NaCl [50] .
doi:10.1099/mic.0.000463 pmid:28548036 fatcat:rp6lbdlzwbdlxbgvdletxgywue

A genome-scale metabolic network reconstruction of extremely halophilic bacterium Salinibacter ruber

Maryam Bagheri, Sayed-Amir Marashi, Mohammad Ali Amoozegar, Kandasamy Ulaganathan
2019 PLoS ONE  
(XLSX) Writing -review & editing: Sayed-Amir Marashi, Mohammad Ali Amoozegar.  ... 
doi:10.1371/journal.pone.0216336 pmid:31071110 pmcid:PMC6508672 fatcat:kdjznbneebdtngx4th25danyhu

Isolation, screening and identification of haloarchaea with chitinolytic activity from hypersaline lakes of Iran

Maryam Yavari-Bafghi, Hamid Babavalian, Mohammad Amoozegar
2019 Archives of Biological Sciences  
Halophiles produce stable enzymes under extreme conditions. The scant information about chitinolytic haloarchaea led us to conduct the present study in order to isolate and screen native halophilic archaea with chitinolytic activity and to optimize the enzyme production conditions. Among 500 haloarchaeal strains isolated from water samples from different hypersaline lakes of Iran, five strains showed chitinolytic activity. Based on biochemical, morphological and molecular analyses, we
more » ... d that all five potent strains belonged to the genus Natrinema. Besides, observing chitinase function in culture media, through an additional molecular test the presence of the chitinase gene in chitinase-producing strains was also confirmed by PCR amplification. Compared with other potent strains, Natrinema sp. strain BS5 showed significant chitinase production. The production of chitinase in strain BS5 accompanied growth, started at the logarithmic phase and increased to its maximum level at the beginning of the stationary phase. Maximum chitinase production was obtained at 37˚C, pH 7.5, 3 M NaCl and 1% colloidal chitin. The strain BS5 showed 38%, 30%, 24% and 28% decreases in enzyme production at 40˚C, pH 8, 3.5 M NaCl and 0.5% substrate, respectively. This strain was able to produce the enzyme in NaCl 4 M and in the absence of MgCl 2 and MgSO 4 . This study revealed the strong potential of the genus Natrinema to produce chitinase at high salt concentrations without Mg 2+ requirement.
doi:10.2298/abs180525049y fatcat:xilb2iet25drbm27qzh7jxbe5i

Exploring the potential of halophilic archaea for the decolorization of azo dyes

Masoomeh Selseleh Hassan Kiadehi, Mohammad Ali Amoozegar, Sedigheh Asad, Maryam Siroosi
2018 Water Science and Technology  
. ; Amoozegar et al. ; Pourbabaee et al. ) .  ... 
doi:10.2166/wst.2018.040 pmid:29595162 fatcat:lraibb3hcrczpbip4z3ahbgqga

Genome-resolved analyses show an extensive diversification in key aerobic hydrocarbon-degrading enzymes across bacteria and archaea [article]

Maryam Rezaei Somee, Mohammad Ali Amoozegar, Seyed Mohammad Mehdi Dastgheib, Mahmoud Shavandi, Leila Ghanbari Maman, Stefan Bertilsson, Maliheh Mehrshad
2022 bioRxiv   pre-print
Hydrocarbons (HCs) are organic compounds composed solely of carbon and hydrogen. They mainly accumulate in oil reservoirs, but aromatic HCs can also have other sources and are widely distributed in the biosphere. Our perception of pathways for biotic degradation of major HCs and genetic information of key enzymes in these bioconversion processes have mainly been based on cultured microbes and are biased by uneven taxonomic representation. Here we use Annotree to provide a gene-centric view of
more » ... robic degradation of aliphatic and aromatic HCs in a total of 23446 genomes from 123 bacterial and 14 archaeal phyla. Apart from the widespread genetic potential for HC degradation in Proteobacteria, Actinobacteriota, Bacteroidota, and Firmicutes, genomes from an additional 18 bacterial and 3 archaeal phyla also hosted key HC degrading enzymes. Among these, such degradation potential has not been previously reported for representatives in the phyla UBA8248, Tectomicrobia, SAR324, and Eremiobacterota. While genomes containing full pathways for complete degradation of HCs were only detected in Proteobacteria and Actinobacteriota, other lineages capable of mediating such key steps could partner with representatives with truncated HC degradation pathways and collaboratively drive the process. Phylogeny reconstruction shows that the reservoir of key aerobic hydrocarbon-degrading enzymes in Bacteria and Archaea undergoes extensive diversification via gene duplication and horizontal gene transfer. This diversification could potentially enable microbes to rapidly adapt to novel and manufactured HCs that reach the environment.
doi:10.1101/2022.06.22.496985 fatcat:cbde35bx3nbw3j6omke3zzg53u

Distinct microbial communities along the chronic oil pollution continuum of the Persian Gulf converge with oil spill accidents [article]

Maryam Rezaei Somee, Seyed Mohammad Mehdi Dastgheib, Mahmoud Shavandi, Leila Ghanbari Maman, Kaveh Kavousi, Mohammad Ali Amoozegar, Maliheh Mehrshad
2020 bioRxiv   pre-print
Persian Gulf hosting ca. 48% of the world's oil reserves; has been chronically exposed to natural oil seepage. Oil spill events have been studied over the last decade; however, the influence of chronic oil exposure on the microbial community of the Persian Gulf has remained unknown. We performed genome-resolved comparative analyses of the water and sediment's prokaryotic community along the Gulf's pollution continuum (Strait of Hormuz, Asalouyeh and Khark Island). The continuous exposure to
more » ... e amounts of pollution has shifted the microbial profile toward the dominance of Oceanospirillales, Flavobacteriales, Alteromonadales, and Rhodobacterales in Asalouyeh and Khark samples. Intrinsic oil-degrading microbes present in low abundances in marine habitats; experience a bloom in response to oil pollution. Comparative analysis of the Persian Gulf samples with 106 oil-polluted marine samples reveals the pollutant's hydrocarbon content, exposure time and sediment depth as main determinants of microbial response to pollution. High aliphatic content enriches for Oceanospirillales, Alteromonadales and Pseudomonadales whereas, Alteromonadales, Cellvibrionales, Flavobacteriales and Rhodobacterales dominate polyaromatic polluted samples. In sediment samples, Deltaproteobacteria and Gammaproteobacteria had the highest abundance. In chronic exposure and oil spill events, the community composition converges towards higher dominance of oil-degrading constituents while promoting the division of labor for successful bioremediation.
doi:10.1101/2020.07.25.221044 fatcat:lxscfllt6neufibyccd7l73idq

Oceanobacillus halophilus sp. nov., a novel moderately halophilic bacterium from a hypersaline lake

Mohammad Ali Amoozegar, Maryam Bagheri, Ali Makhdoumi, Mahdi Moshtaghi Nikou, Seyed Abolhassan Shahzadeh Fazeli, Peter Schumann, Cathrin Spröer, Cristina Sánchez-Porro, Antonio Ventosa
2016 International Journal of Systematic and Evolutionary Microbiology  
., 2010; Amoozegar et al., 2014) and activated sludge (Yang et al., 2010) .  ... 
doi:10.1099/ijsem.0.000952 pmid:26869142 fatcat:msauundcare4zjze4rd5cogvwi

The effect of consultancy on phone after hospital discharge on self-efficacy of mothers of children with congenital heart disease: A quasi-experimental study

Mitra Soltanian, Maryam Nikroo, Sedigheh Montaseri, Hamid Amoozegar
2021 Sri Lanka Journal of Child Health  
The parents of children with congenital heart disease (CHD) are faced with multiple needs such as home care of children and medicinal care after the child is discharged from hospital. Objectives: To assess the effect of consultancy on phone after hospital discharge on self-efficacy of mothers of children with CHD.
doi:10.4038/sljch.v50i2.9557 fatcat:e2dqleyoozgdtj6f26fkio7coi

Antibacterial, Antioxidant, and Anticancer Activities of Biosynthesized Selenium Nanoparticles Using Two Indigenous Halophilic Bacteria

Maryam Tabibi, Seyed Soheil Agaei, Mohammad Ali Amoozegar, Razieh Nazari, Mohammad Reza Zolfaghari, Department of Microbiology, Qom Branch, Islamic Azad University, Qom, Iran, Department of Microbiology, Qom Branch, Islamic Azad University, Qom, Iran, Extremophiles Laboratory, Department of Microbiology, Faculty of Biology and Center of Excellence in Phylogeny of Living Organisms, College of Science, University of Tehran, Tehran, Iran, Department of Microbiology, Qom Branch, Islamic Azad University, Qom, Iran, Department of Microbiology, Qom Branch, Islamic Azad University, Qom, Iran
2020 Archives of Hygiene Sciences  
doi:10.52547/archhygsci.9.4.275 fatcat:kzhgkjmr75baxnhrtj76feusni

Isolation and Discovery of New Antimicrobial-agent Producer Strains Using Antibacterial Screening of Halophilic Gram-positive Endospore-forming Bacteria Isolated from Saline Lakes of Iran

Asefeh Dahmardeh Ghalehno, Maryam Ghavidel-Aliabadi, Zeinab Shahmohamadi, Maliheh Mehrshad, Mohammad Amoozegar, Abolghasem Danesh
2018 Arak Medical University Journal (AMUJ)   unpublished
Today, discovery and production of new antimicrobial drugs has been emphasized due to the growing of antimicrobial resistance. The purpose of this study was to screen out antimicrobial producing bacteria among halophilic or halotolerant Gram-positive endospore-forming bacteria isolated from different areas of Iran. Materials and Methods: 62 strains were isolated from salin lakes of Iran, endospore-forming ability was evaluated and further identification of strains was done using 16S rRNA gene
more » ... quencing. Screening test was performed using two-layer agar diffusion method in which the indicator strains, Bacillus cereus (ATCC 14579) and Escherichia coli, (PTCC 1330) were inoculated in the seed layer. Finally, the production of antimicrobial active agent during a period of 7 days was studied followed by evaluating the effect of base-layer agar concentration on the dissemination of antibacterial metabolite. Results: Isolates WT6, R4A19 produced an agent(s) which inhibited the growth of both B.cereuse and E.Coli. The inhibition zone against only E.Coli was observed when R4A20 strain had been cultured in the base layer, while four non-bacillus strains (R4S2, LbS2, RF1 and WT19) could inhibit the growth of B.cereuse. The antibacterial compound production of WT6 against Bacillus cereuse and E.Coli reached to its optimumm leved after 3 and 4 days respectively, while R4A20 produced the active substance, optimally, after 5 days. No significant difference effect on diameter of zone inhibition was observed among various base-layer agar concentrations. Conclusion: Halophile or halotolerant endospore-forming bacteria isolated from different areas of Iran possess a potential to be considered as interesting microorganisms for further antimicrobial research studies.
fatcat:lgruncnhvjekzjqs36cl3774j4

Isolation and Discovery of New Antimicrobial-agent Producer Strains Using Antibacterial Screening of Halophilic Gram-positive Endospore-forming Bacteria Isolated from Saline Lakes of Iran

Asefeh Dahmardeh Ghalehno, Maryam Ghavidel-Aliabadi, Zeinab Shahmohamadi, Maliheh Mehrshad, Mohammad Amoozegar, Abolghasem Danesh
2018 Arak Medical University Journal (AMUJ)   unpublished
Today, discovery and production of new antimicrobial drugs has been emphasized due to the growing of antimicrobial resistance. The purpose of this study was to screen out antimicrobial producing bacteria among halophilic or halotolerant Gram-positive endospore-forming bacteria isolated from different areas of Iran. Materials and Methods: 62 strains were isolated from salin lakes of Iran, endospore-forming ability was evaluated and further identification of strains was done using 16S rRNA gene
more » ... quencing. Screening test was performed using two-layer agar diffusion method in which the indicator strains, Bacillus cereus (ATCC 14579) and Escherichia coli, (PTCC 1330) were inoculated in the seed layer. Finally, the production of antimicrobial active agent during a period of 7 days was studied followed by evaluating the effect of base-layer agar concentration on the dissemination of antibacterial metabolite. Results: Isolates WT6, R4A19 produced an agent(s) which inhibited the growth of both B.cereuse and E.Coli. The inhibition zone against only E.Coli was observed when R4A20 strain had been cultured in the base layer, while four non-bacillus strains (R4S2, LbS2, RF1 and WT19) could inhibit the growth of B.cereuse. The antibacterial compound production of WT6 against Bacillus cereuse and E.Coli reached to its optimumm leved after 3 and 4 days respectively, while R4A20 produced the active substance, optimally, after 5 days. No significant difference effect on diameter of zone inhibition was observed among various base-layer agar concentrations. Conclusion: Halophile or halotolerant endospore-forming bacteria isolated from different areas of Iran possess a potential to be considered as interesting microorganisms for further antimicrobial research studies.
fatcat:etnq6bjywzecdjiucdvoyqzpvy

Isolation and Discovery of New Antimicrobial-agent Producer Strains Using Antibacterial Screening of Halophilic Gram-positive Endospore-forming Bacteria Isolated from Saline Lakes of Iran

Asefeh Dahmardeh Ghalehno, Maryam Ghavidel-Aliabadi, Zeinab Shahmohamadi, Maliheh Mehrshad, Mohammad Amoozegar, Abolghasem Danesh
2018 Arak Medical University Journal (AMUJ)   unpublished
Today, discovery and production of new antimicrobial drugs has been emphasized due to the growing of antimicrobial resistance. The purpose of this study was to screen out antimicrobial producing bacteria among halophilic or halotolerant Gram-positive endospore-forming bacteria isolated from different areas of Iran. Materials and Methods: 62 strains were isolated from salin lakes of Iran, endospore-forming ability was evaluated and further identification of strains was done using 16S rRNA gene
more » ... quencing. Screening test was performed using two-layer agar diffusion method in which the indicator strains, Bacillus cereus (ATCC 14579) and Escherichia coli, (PTCC 1330) were inoculated in the seed layer. Finally, the production of antimicrobial active agent during a period of 7 days was studied followed by evaluating the effect of base-layer agar concentration on the dissemination of antibacterial metabolite. Results: Isolates WT6, R4A19 produced an agent(s) which inhibited the growth of both B.cereuse and E.Coli. The inhibition zone against only E.Coli was observed when R4A20 strain had been cultured in the base layer, while four non-bacillus strains (R4S2, LbS2, RF1 and WT19) could inhibit the growth of B.cereuse. The antibacterial compound production of WT6 against Bacillus cereuse and E.Coli reached to its optimumm leved after 3 and 4 days respectively, while R4A20 produced the active substance, optimally, after 5 days. No significant difference effect on diameter of zone inhibition was observed among various base-layer agar concentrations. Conclusion: Halophile or halotolerant endospore-forming bacteria isolated from different areas of Iran possess a potential to be considered as interesting microorganisms for further antimicrobial research studies.
fatcat:cpgvlzqchzchrosphml77jltl4

Isolation and Discovery of New Antimicrobial-agent Producer Strains Using Antibacterial Screening of Halophilic Gram-positive Endospore-forming Bacteria Isolated from Saline Lakes of Iran

Asefeh Dahmardeh Ghalehno, Maryam Ghavidel-Aliabadi, Zeinab Shahmohamadi, Maliheh Mehrshad, Mohammad Amoozegar, Abolghasem Danesh
2018 Arak Medical University Journal (AMUJ)   unpublished
Today, discovery and production of new antimicrobial drugs has been emphasized due to the growing of antimicrobial resistance. The purpose of this study was to screen out antimicrobial producing bacteria among halophilic or halotolerant Gram-positive endospore-forming bacteria isolated from different areas of Iran. Materials and Methods: 62 strains were isolated from salin lakes of Iran, endospore-forming ability was evaluated and further identification of strains was done using 16S rRNA gene
more » ... quencing. Screening test was performed using two-layer agar diffusion method in which the indicator strains, Bacillus cereus (ATCC 14579) and Escherichia coli, (PTCC 1330) were inoculated in the seed layer. Finally, the production of antimicrobial active agent during a period of 7 days was studied followed by evaluating the effect of base-layer agar concentration on the dissemination of antibacterial metabolite. Results: Isolates WT6, R4A19 produced an agent(s) which inhibited the growth of both B.cereuse and E.Coli. The inhibition zone against only E.Coli was observed when R4A20 strain had been cultured in the base layer, while four non-bacillus strains (R4S2, LbS2, RF1 and WT19) could inhibit the growth of B.cereuse. The antibacterial compound production of WT6 against Bacillus cereuse and E.Coli reached to its optimumm leved after 3 and 4 days respectively, while R4A20 produced the active substance, optimally, after 5 days. No significant difference effect on diameter of zone inhibition was observed among various base-layer agar concentrations. Conclusion: Halophile or halotolerant endospore-forming bacteria isolated from different areas of Iran possess a potential to be considered as interesting microorganisms for further antimicrobial research studies.
fatcat:k2qxb4d6ivhulbloe2e2vesqaa

Isolation and Discovery of New Antimicrobial-agent Producer Strains Using Antibacterial Screening of Halophilic Gram-positive Endospore-forming Bacteria Isolated from Saline Lakes of Iran

Asefeh Dahmardeh Ghalehno, Maryam Ghavidel-Aliabadi, Zeinab Shahmohamadi, Maliheh Mehrshad, Mohammad Amoozegar, Abolghasem Danesh
2018 Arak Medical University Journal (AMUJ)   unpublished
Today, discovery and production of new antimicrobial drugs has been emphasized due to the growing of antimicrobial resistance. The purpose of this study was to screen out antimicrobial producing bacteria among halophilic or halotolerant Gram-positive endospore-forming bacteria isolated from different areas of Iran. Materials and Methods: 62 strains were isolated from salin lakes of Iran, endospore-forming ability was evaluated and further identification of strains was done using 16S rRNA gene
more » ... quencing. Screening test was performed using two-layer agar diffusion method in which the indicator strains, Bacillus cereus (ATCC 14579) and Escherichia coli, (PTCC 1330) were inoculated in the seed layer. Finally, the production of antimicrobial active agent during a period of 7 days was studied followed by evaluating the effect of base-layer agar concentration on the dissemination of antibacterial metabolite. Results: Isolates WT6, R4A19 produced an agent(s) which inhibited the growth of both B.cereuse and E.Coli. The inhibition zone against only E.Coli was observed when R4A20 strain had been cultured in the base layer, while four non-bacillus strains (R4S2, LbS2, RF1 and WT19) could inhibit the growth of B.cereuse. The antibacterial compound production of WT6 against Bacillus cereuse and E.Coli reached to its optimumm leved after 3 and 4 days respectively, while R4A20 produced the active substance, optimally, after 5 days. No significant difference effect on diameter of zone inhibition was observed among various base-layer agar concentrations. Conclusion: Halophile or halotolerant endospore-forming bacteria isolated from different areas of Iran possess a potential to be considered as interesting microorganisms for further antimicrobial research studies.
fatcat:vyjjvsyjoba63ksvouqfxbt6s4
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