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Novel Physiotherapy Approach for Multiple Sclerosis

Elzbieta Miller Marta Niwald
2014 Journal of Novel Physiotherapies  
Multiple sclerosis is a chronic, complex disease with a variety of clinical symptoms and affects mainly young and middle-aged people. Research and therapies are focused on the early phase of MS, especially relapsing-remitting MS (RRMS). There is the need for novel therapeutic strategies especially oriented towards neuroprotection in the chronic phase. Accumulating data outlines the beneficial role of physiotherapy in individuals with MS. A physiotherapy program improves muscle strength,
more » ... walking capacity and decreases spasticity, while also enhancing mood, cognitive function and reducing fatigue. Currently, neurorehabilitation programs are among the most popular therapies for reducing the disabilities and social disadvantages of MS patients. Rehabilitation strategies in MS should be based on the promotion of motor learning-related neuroplasticity improving functional outcomes. Therefore, the interdisciplinary team is essential for maximizing the patient's ability to function. In this review current treatment, symptoms and clinical phenotypes, the role of rehabilitation, main measures that are recommended to estimate disability, impairment and handicap of MS are presented. Additionally, aerobic training as a factor enhances cognitive function by upregulation of neurotrophins, such as brain-derived neurotrophic factor (BDNF) was showed. First of all this review focuses on the novel methods used in multiple sclerosis patients including telerehabilitation and cryostimulation.
doi:10.4172/2165-7025.1000228 fatcat:bjnt4piyfnawpjfytthggwkr2y

Sports result vs. general physical fitness level of junior taekwondo athletes

Jerzy Miller, Zbigniew Bujak, Marta Miller
2011 Journal of Combat Sports and Martial Arts  
6% 28% 14% 15% Groups of subjects Mean values of IPFT (pts) Difference girls Boys Gold medallists 526 469 11% Silver medallists 524 423 19% Bronze medallists 488 464 5% Miller  ... 
doi:10.5604/20815735.1047123 fatcat:iqy4upxp2vdbpb5wkk35jtgtke

Distribution, the forgotten element in transnational cinema

Toby Miller, Freya Schiwy, Marta Hernández Salván
2012 Transnational cinemas  
These unproven, utopic predictions prove vulnerable when they are examined empirically (Miller 2009 ).  ...  For example, in 1922 several Latin American countries, Canada, France and Spain placed embargoes on imports from the United States because of the repugnant 'greaser' genre (Gomery 1992: 171, 177, 179; Miller  ... 
doi:10.1386/trac.2.2.197_1 fatcat:2mfefjbxq5aofkgth4cklb235i

Burnaia Miller, 2001 (Gastropoda, Heterobranchia, Nudibranchia): a facelinid genus with an Aeolidiidae's outward appearance

Leila Carmona, Marta Pola, Terrence M. Gosliner, Juan Lucas Cervera
2015 Helgoland Marine Research  
As Miller (1987 Miller ( , 2001 pointed out, in body shape B. helicochorda resembles Limenandra nodosa and L. fusiformis.  ...  According to Miller (1987 Miller ( , 2001 , this species was of easy identification by its external colouration, large body, lamellate rhinophores, and cerata in arches.  ... 
doi:10.1007/s10152-015-0437-4 fatcat:guaqmvxpnnghzkuqjjdqssfyoi

Health Physics Technician Injury Reduction

Stephen Bump, Dianne Whitten, Marta Caballero, Judy Banaszynski, Kathy Keelean, John Miller
2002 Health Physics  
As part of a safety sirrnmit sponsored by Fliior Harrford Occrrpationnl Heulth rlrlit S~f i t y , it was tlOted that H e~l t h Phy.yics Trclrrriciiiris (HPTs) IILIVO orze of the highest injury riitos nt Huriforri. A rnirlti-disci~~lined tiwin made up of HPTs, lieulth physics professionals, liedtli plrysics rnnnagernent, irzrlirstrial hygienists, czritl niedical personriel was i~strrblisheti to rleterrnirie causes arid corrective cictiotis. Cotnmittw activities included rrvicwiiig curd
more » ... rizirig oc~cupational injuries arid illnesses, assmirig areas afectirzg the Iieulth of HPTs, soliciting field input, pcrforrriitig field evalrrtitions of tasks, and rnnkirig rec~~mi~i~n~atiorzs for itnprovetnerits to senior iir~iriuprnrrit. Five urms showed a l 7~d fi)r iinrnt~liczte iniprovenwnt: rnmmaclriric interface (liirmari factors and ergoriomiis), work er~vironrnent, procedures, peoplp, rind coriimirrrications. A key area of risk iderltifieri is the lack of er,yonornic design consirterntiom of tlie survey instruments currently i m d . TIieri, are sevrral CUSKS of curnuliztive trmrmu disorder reqiiiririg surgery. Tliese mse.s are dirz~tly related to use of health pliy.cic:s irzstrirrrrerrt~?tiorr and/or siirvey t t d i n i i p s . The cornniittec his made ergoriornics L711d instrrtrnerit retlcsi'~~i/rriotlification its kty iriitiutive fir 2001. The cornmittee is eiicoirrugirig veiirior support arid is seeking fe~dback from other lrealth physics orgunizatior is rqanliri'y their experience and any recorntrieriitritiota tlrey woirlti like to make. Some A 99352, of I W I I~/ (it .\t~;o/icri_?_brrin~)~~l.~uv. wccers has already been achieved through an ergonomics-training program airned a t all HPTr and their supervisors. In addition, there have been several chariges made to the way surveys are conducted, survey fiequencies have been reduced, and the way rnodifications have been made to existing instrumentation. This i s a long-tern initiative with broad support within the Hanford HPT community. This doociment reports the progres made thus far on the initiative. Health Phys. 82(Supplernent 5):S92-S96; 2002
doi:10.1097/00004032-200205001-00012 pmid:12003036 fatcat:cwnk45wlgbbmjhxlrwnna4qx7e

Stability of synthetic cathinones in oral fluid samples

Briana Miller, Jiyoung Kim, Marta Concheiro
2017 Forensic Science International  
Synthetic cathinones are new stimulant drugs derived from cathinone that have been sold as "legal highs" worldwide. These compounds can elicit powerful effects such as delusions, hallucinations as well as other potentially dangerous behavior. New analogs with varying effects and potencies are constantly introduced in the market to evade legislation, and they are not detected by routine screening and confirmation methods. Oral fluid is an alternative matrix of increasing interest in forensic
more » ... cology. Its collection is non-invasive and easily supervised, and positive drug findings typically reflect recent drug exposure. The focus of this research was to develop a method for the determination of 10 synthetic cathinones (cathinone, methcathinone, buphedrone, mephedrone, 4methylethcathinone, 3,4-methylenedioxypyrovalerone (MDPV), methylone, naphyrone, alpha-pyrrolidinovalerophenone (PVP) and N-ethylcathinone) in preserved oral fluid (Quantisal TM ), as well as evaluate their stability in preserved (Quantisal and Oral-Eze TM ) and neat oral fluid samples stored under different conditions, using ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MSMS). Four-hundred μL oral fluid-Quantisal buffer mixture (100 μL oral fluid and 300 μL buffer) were subjected to cation exchange solid phase extraction. The chromatographic reverse-phase separation was achieved with a gradient mobile phase of 0.1 % formic acid in water and in acetonitrile in 5 min. We used a Shimadzu triple quadrupole mass spectrometer in multiple reaction monitoring (MRM) mode. The assay was linear from 1-250 ng/mL, with the limits of detection of 0.75-1 ng/mL. Imprecision (n=15) was <20.7% and accuracy (n=15) was 84-115.3%. Extraction efficiency was 87.2-116.8% (n=6), process efficiency was 30.9-103.7% (n=6), and matrix effect was -65.1 to -6.2% n=6). The stability was performed for neat oral fluid, oral fluid in Quantisal buffer, and oral fluid in Oral-Eze buffer samples stored up to one month at room temperature, 4 o C and -20 o C, and after 3 freezethaw cycles. Losses up to -71.2 to -100% were observed in neat and preserved samples stored at room temperature up to one month. At 4 o C, losses up to -88.2% occurred in neat OF and Oral-Eze samples, while Quantisal samples showed losses up to -34%. All types samples were stable if stored at -20 o C and after 3 freeze-thaw cycles.
doi:10.1016/j.forsciint.2016.11.034 pmid:27916403 fatcat:qmtu24sshjbafdzz4oab44quza

Quarantine Activity Reporting System (QARS)

Ramesh Krishnamurthy, Martha Remis, Leonora Brooke, Charles Miller, Ava Navin, Marta Guerra
2006 AMIA Annual Symposium Proceedings  
This poster describes the Quarantine Activity Reporting System (QARS), a new web based,secure electronic system which enables tracking the presence of ill persons on inbound flights and vessels and at land border crossings, infectious disease threats, or actions related to imported pathogens.
pmid:17238609 pmcid:PMC1839249 fatcat:52o7rwnlarb3loa467ukjxro7u

Muscle power, contraction velocity and functional performance after stroke

Joanna Kostka, Marta Niwald, Agnieszka Guligowska, Tomasz Kostka, Elżbieta Miller
2019 Brain and Behavior  
Muscle strength and its role in everyday functioning in patients after stroke are most often described in the literature (Bohannon, 2007; Kostka, Czernicki, Pruszyńska, & Miller, 2017) .  ...  With the exception of our preliminary study (Kostka, Fajkowska, & Miller, 2017) , in the available literature we have found only one study in which the deficit of maximal muscle power in stroke survivors  ... 
doi:10.1002/brb3.1243 pmid:30821102 pmcid:PMC6456770 fatcat:lluzyosewrfj5ccauqkqppgwwi

Thermomodernization of buildings with the utilization of green walls

Małgorzata Wesołowska, Marta Laska, B. Kaźmierczak, P. Jadwiszczak, M. Kutyłowska, U. Miller
2019 E3S Web of Conferences  
The revitalization of historical buildings is a subject that is increasingly being discussed around the world. This is connected with the goal set by the European and thus Polish and local policy to reduce energy consumption in existing buildings. The publication presents an unconventional solution for thermal modernization of buildings with the utilization of green walls. The article presents the literature and legal acts review on green walls, their construction and impact on existing
more » ... s. It describes the benefits and disadvantages resulting from the use of vegetation on the external walls. Additionally the possibility of using green walls at the historic facility located in Wroclaw (Poland) is presented.
doi:10.1051/e3sconf/201910000085 fatcat:fwkqf5n3bjfb3f56tiedfrf5sq

Mindfulness Correlates with Stress and Coping in University Students

Carlin J Miller, Emily-Ann Di Pierdomenico, Marta Kadziolka
2017 Canadian Journal of Higher Education  
Miller  ...  Marta Kadziolka is a doctoral student in the clinical psychology program at the University of Windsor.  ...  Carlin Miller is an associate professor in the Psychology Department and within the Behaviour, Cognition, and Neuroscience Program at the University of Windsor.  ... 
doi:10.47678/cjhe.v47i2.187383 fatcat:tp67fggqpvaedpjayytehssasi

The protein kinase SIK downregulates the polarity protein Par3

Michael Vanlandewijck, Mahsa Shahidi Dadras, Marta Lomnytska, Tanzila Mahzabin, Martin Lee Miller, Christer Busch, Søren Brunak, Carl-Henrik Heldin, Aristidis Moustakas
2017 OncoTarget  
Supplementary Figure 1 : Sequence alignment of the predicted phosphorylation site across species. The predicted phosphorylation site for SIK in Par3 is aligned with its orthologs in selected species. The phosphorylated serine is indicated in black, while the conserved amino acids are depicted in green. A consensus phosphorylation motif is shown at the bottom.
doi:10.18632/oncotarget.23788 pmid:29464029 pmcid:PMC5814169 fatcat:6xhfuczdtfcftki32qbqbtwcka

Myosin VI Regulates Actin Structure Specialization through Conserved Cargo-Binding Domain Sites

Mamiko Isaji, Marta Lenartowska, Tatsuhiko Noguchi, Deborah J. Frank, Kathryn G. Miller, Thierry Soldati
2011 PLoS ONE  
Citation: Isaji M, Lenartowska M, Noguchi T, Frank DJ, Miller KG (2011) Myosin VI Regulates Actin Structure Specialization through Conserved Cargo-Binding Domain Sites. PLoS ONE 6(8): e22755.  ...  Kathleen Beckingham, Ram Dixit, and Meg Titus, as well as members of the Miller laboratory, for critical reading of the manuscript. Author Contributions  ... 
doi:10.1371/journal.pone.0022755 pmid:21853045 pmcid:PMC3154908 fatcat:y5ezujaj65do7le4hbhlx3ftqu

Moderate positive spin Hall angle in uranium

Simranjeet Singh, Marta Anguera, Enrique del Barco, Ross Springell, Casey W. Miller
2015 Applied Physics Letters  
We report measurements of spin pumping and the inverse spin Hall effect in Ni80Fe20/Uranium bilayers designed to study the efficiency of spin-charge interconversion in a super-heavy element. We employ broad-band ferromagnetic resonance on extended films to inject a spin current from the Ni80Fe20 (permalloy) into the uranium layer, which is then converted into an electric field by the inverse spin Hall effect. Surprisingly, our results suggest a spin mixing conductance of order 2x10 e19 m-2 and
more » ... positive spin Hall angle of 0.004, which are both merely comparable to those of several transition metals. These results thus support the idea that the electronic configuration may be at least as important as the atomic number in governing spin pumping across interfaces and subsequent spin Hall effects. In fact, given that both the magnitude and the sign are unexpected based on trends in d-electron systems, materials with unfilled f-electron orbitals may hold additional exploration avenues for spin physics.
doi:10.1063/1.4936999 fatcat:t562bfjhvra3bnfvurdbw6lkbm

Association of miRNA and mRNA Levels of the Clinical Onset of Multiple Sclerosis Patients

Danuta Piotrzkowska, Elzbieta Miller, Ewa Kucharska, Marta Niwald, Ireneusz Majsterek
2021 Biology  
Multiple sclerosis (MS) is a demyelinating disease characterized by chronic inflammation of the central nervous system, in which many factors can act together to influence disease susceptibility and progression. To date, the exact cause of MS is still unclear, but it is believed to result from an abnormal response of the immune system to one or more myelin antigens that develops in genetically susceptible individuals after their exposure to a, as yet undefined, causal agent. In our study, we
more » ... essed the effect of microRNAs on the expression level of neuroprotective proteins, including neurotrophins (BDNF and NT4/5), heat shock proteins (HSP70 and HSP27), and sirtuin (SIRT1) in peripheral blood mononuclear cells in the development of multiple sclerosis. The analysis of dysregulation of miRNA levels and the resulting changes in target mRNA/protein expression levels could contribute to a better understanding of the etiology of multiple sclerosis, as well as new alternative methods of diagnosis and treatment of this disease. The aim of this study was to find a link between neurotrophins (BDNF and NT4), SIRT1, heat shock proteins (HSP27 and HSP27), and miRNAs that are involved in the development of multiple sclerosis. The analysis of the selected miRNAs showed a negative correlation of SIRT1 with miR-132 and miR-34a and of BDNF with 132-3p in PBMCs, which suggests that the miRNAs we selected may regulate the expression level of the studied genes.
doi:10.3390/biology10060554 fatcat:p64d5lzisnhm7h5e6h6spxofgy

Research and evaluation of water quality in outdoor swimming pools

Joanna Wyczarska-Kokot, Anna Lempart, Marta Marciniak, B. Kaźmierczak, P. Jadwiszczak, M. Kutyłowska, U. Miller
2019 E3S Web of Conferences  
The article presents the assessment of the quality of water in outdoor pools, based on the results of bacteriological and physicochemical tests and their comparison with the admissible values in this respect. The analyzes were carried out during two bathing seasons, in 2017 and 2018. The quality of water from sports, recreational and children's pools was analyzed, as well as water introduced into the pools from the circulation systems. The decisive role in the assessment of pool water quality
more » ... played by the results of microbiological tests and the assessment of the sanitary condition of the facility. In pool water and circulatory water samples, the number of indicator microorganisms (CFU) did not exceed the limit values. The problem was the very high levels of chloroform (> 0.03 mg/L) and THM (> 0.1 mg/L), lower than the required redox values (750 mV) and nitrate content, increasing over the bathing season. Considering that the analyzed pools are seasonal and recreational outdoor pools, the observed excessive concentrations of DBP, with a short exposure, did not pose a direct threat to the health of bathers. However, they indicate the need to supervise the processes of water treatment and disinfection or their modernization.
doi:10.1051/e3sconf/201910000089 fatcat:k7widlbk3vdk5da55ghpvjxgwi
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