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Silhouette-Based Markerless Motion Estimation of Awake Rodents in PET

Andre Z. Kyme, Paul Strenge, Felicity Lee, Steven R. Meikle
2017 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)  
head motion; and no acclimatization of the animals to attached markers.  ...  Markerless optical approaches for pose estimation have several potential advantages over marker-based methods: improved accuracy and increased range of detectable motion; no 'decoupling' of marker and  ...  INTRODUCTION The ability to image the brain of a freely moving rodent using motion-compensated positron emission tomography (PET) presents many exciting possibilities for exploring the links between brain  ... 
doi:10.1109/nssmic.2017.8532895 fatcat:loq74fjthvemroasom2uunyfoq

Translation of Preclinical PET Imaging Findings: Challenges and Motion Correction to Overcome the Confounding Effect of Anesthetics

Alan Miranda, Daniele Bertoglio, Sigrid Stroobants, Steven Staelens, Jeroen Verhaeghe
2021 Frontiers in Medicine  
Preclinical brain positron emission tomography (PET) in animals is performed using anesthesia to avoid movement during the PET scan.  ...  In contrast, brain PET scans in humans are typically performed in the awake subject.  ...  INTRODUCTION Positron emission tomography (PET) is a molecular imaging technique that allows to quantify the distribution of radiolabeled biomolecules in the living body.  ... 
doi:10.3389/fmed.2021.753977 pmid:34746189 pmcid:PMC8569248 fatcat:m7dut6kdgrh6bhsf3ajrgiurge

Image-based modelling of residual blurring in motion corrected small animal PET imaging using motion dependent point spread functions

G I Angelis, J E Gillam, A Z Kyme, R R Fulton, S R Meikle
2018 Biomedical engineering and physics express  
This apparent loss of resolution can be attributed, among others, to jitter/noise in the measured motion estimates and brief periods of fast animal motion with insufficient motion sampling rate.  ...  Optical motion tracking and motion compensation reconstruction algorithms enable the acquisition of quantitative measurements of brain function on conscious and freely moving rodents.  ...  John Gillam was supported by the University of Sydney Postdoctoral Fellowship.  ... 
doi:10.1088/2057-1976/aab922 fatcat:cblgoj3qdncytg7dyphb2rjthm

The effect of isoflurane on 18F-FDG uptake in the rat brain: a fully conscious dynamic PET study using motion compensation

Matthew G. Spangler-Bickell, Bart de Laat, Roger Fulton, Guy Bormans, Johan Nuyts
2016 EJNMMI Research  
In preclinical positron emission tomography (PET) studies an anaesthetic is used to ensure that the animal does not move during the scan.  ...  Motion tracking can either be marker-based [10, 11], where a small marker is attached to the head of the animal and tracked by external cameras, or markerless, where the facial features of the animal are  ...  Acknowledgments The authors would like to acknowledge the help of Julie Cornelis and Tao Sun during the rat training and scans, and Willy Gsell, Michel Koole and Patrick Dupont for the many helpful discussions  ... 
doi:10.1186/s13550-016-0242-3 pmid:27888500 pmcid:PMC5124015 fatcat:umfcgxnxtfe4ncgxrixbpckft4

Markerless motion tracking and correction for PET, MRI, and simultaneous PET/MRI

Jakob M. Slipsager, Andreas H. Ellegaard, Stefan L. Glimberg, Rasmus R. Paulsen, M. Dylan Tisdall, Paul Wighton, André van der Kouwe, Lisbeth Marner, Otto M. Henriksen, Ian Law, Oline V. Olesen, Qinghui Zhang
2019 PLoS ONE  
We demonstrate and evaluate the first markerless motion tracker compatible with PET, MRI, and simultaneous PET/MRI systems for motion correction (MC) of brain imaging.  ...  They would also like to thank the clinical staff at the department, who collected the tracking data.  ...  Acknowledgments The authors would like to thank the Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Denmark for general support and availability of  ... 
doi:10.1371/journal.pone.0215524 pmid:31002725 pmcid:PMC6474595 fatcat:pceougqtcrd7ne6ikbl77okfsu

2014 Index IEEE Transactions on Medical Imaging Vol. 33

2014 IEEE Transactions on Medical Imaging  
., +, TMI Nov. 2014 2098-2106 Markerless Motion Tracking of Awake Animals in Positron Emission Tomography.  ...  ., +, TMI Jan. 2014 48-60 Optical tracking Markerless Motion Tracking of Awake Animals in Positron Emission Tomography.  ...  ., 1969 -1985 Numerical Surrogates for Human Observers in Myocardial Motion Evaluation From SPECT Images.  ... 
doi:10.1109/tmi.2014.2386278 fatcat:poarfhfto5bm5mhfl7ugwtw4xy


Jiude Li
2015 International Journal on Smart Sensing and Intelligent Systems  
On the basis of the detection and tracking results, the algorithm of motion parameter estimation is analyzed.  ...  Camera-based human body detection and tracking is an important research subject of computer vision, which has a widely used in the field of military and civil.  ...  "Markerless Motion Tracking of Awake Animals in Positron Emission Tomography", IEEE Transactions on Medical Imaging, 2014, 33(11): 2180 -2190, doi: 10.1109/TMI.2014. 2332821. [2] P. J. Noonan, J. M.  ... 
doi:10.21307/ijssis-2017-798 fatcat:25hwwde4n5hjdgbvgo3f5ig7ty

A Systematic Collection of Medical Image Datasets for Deep Learning [article]

Johann Li, Guangming Zhu, Cong Hua, Mingtao Feng, BasheerBennamoun, Ping Li, Xiaoyuan Lu, Juan Song, Peiyi Shen, Xu Xu, Lin Mei, Liang Zhang (+2 others)
2021 arXiv   pre-print
The lack of data in the medical imaging field creates a bottleneck for the application of deep learning to medical image analysis.  ...  The astounding success made by artificial intelligence (AI) in healthcare and other fields proves that AI can achieve human-like performance. However, success always comes with challenges.  ...  Key R&D Program of China under Grant No 2019YFB1311600.  ... 
arXiv:2106.12864v1 fatcat:bjzkgce2xvaexmb6cdznws7fye

Chronic behavioral manipulation via orally delivered chemogenetic actuator in macaques

Kei Oyama, Yukiko Hori, Yuji Nagai, Naohisa Miyakawa, Koki Mimura, Toshiyuki Hirabayashi, Ken-Ichi Inoue, Masahiko Takada, Makoto Higuchi, Takafumi Minamimoto
Pharmacokinetic analysis and positron emission tomography (PET) occupancy examination demonstrated that oral administration of DCZ yielded slower and prolonged kinetics, and that its bioavailability was  ...  10-20% of that in the case of systemic injection.  ...  Pharmacokinetic analysis and positron emission tomography (PET) occupancy examination demonstrated that oral administration of DCZ yielded slower and prolonged kinetics, and that its bioavailability was  ... 
doi:10.1523/jneurosci.1657-21.2021 pmid:35110390 pmcid:PMC8944228 fatcat:xez2ptvbkrdmvd7q6vh7qfwoii