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Mark B. Wiebe. On Evil, Providence, and Freedom: A New Reading of Molina

Zita V. Toth
2018 The Journal of Analytic Theology  
Wiebe does not address this part of the argument.)  ...  Wiebe also regards responsibility and libertarian freedom as interchangeable notions.  ... 
doi:10.12978/jat.2018-6.250800191407a fatcat:vvuuo33cxfgnte2bhmrb6arpkq

The tar monster

Mark Wiebe, Ben Houston
2004 ACM SIGGRAPH 2004 Sketches on - SIGGRAPH '04  
doi:10.1145/1186223.1186303 dblp:conf/siggraph/WiebeH04 fatcat:vf4prlv2zfgullo2yafrf7pndq

Survey Science in Pediatric Emergency Medicine

Mark R. Zonfrillo, Douglas J. Wiebe
2011 Pediatric emergency care  
Surveys conveniently acquire and summarize valuable information from a target population. The specific aims, design, target sample, mode of distribution, data analysis, and inherent limitations of the survey methodology should be carefully considered to maximize the validity of the results. This review provides guidance on the methods and standards necessary to complete sound survey science.
doi:10.1097/pec.0b013e3182187524 pmid:21546814 fatcat:zoowy5ehsjap7b2khnpuhrgsl4

RLE sparse level sets

Ben Houston, Mark Wiebe, Chris Batty
2004 ACM SIGGRAPH 2004 Sketches on - SIGGRAPH '04  
both the RLE sparse level set representation and the above described method of converting animated characters into level sets is used in the creation of the "Tar Monster" production effect described in [Wiebe  ... 
doi:10.1145/1186223.1186394 dblp:conf/siggraph/HoustonWB04 fatcat:md2paselk5dwxaqs3ysmx43cz4

Social laws in alternating time: effectiveness, feasibility, and synthesis

Wiebe van der Hoek, Mark Roberts, Michael Wooldridge
2006 Synthese  
Since it was first proposed by Moses, Shoham, and Tennenholtz, the social laws paradigm has proved to be one of the most compelling approaches to the offline coordination of multiagent systems. In this paper, we make four key contributions to the theory and practice of social laws in multiagent systems. First, we show that the Alternating-time Temporal Logic (atl) of Alur, Henzinger, and Kupferman provides an elegant and powerful framework within which to express and understand social laws for
more » ... ultiagent systems. Second, we show that the effectiveness, feasibility, and synthesis problems for social laws may naturally be framed as atl model checking problems, and that as a consequence, existing atl model checkers may be applied to these problems. Third, we show that the complexity of the feasibility problem in our framework is no more complex in the general case than that of the corresponding problem in the Shoham-Tennenholtz framework (it is np-complete). Finally, we show how our basic framework can easily be extended to permit social laws in which constraints on the legality or otherwise of some action may be explicitly required. We illustrate the concepts and techniques developed by means of a running example.
doi:10.1007/s11229-006-9072-6 fatcat:ol27c4e5fndnjkudpjtdve43tm

A curious cubic identity and self-similar sums of squares

Alf van der Poorten, Kurt Thomsen, Mark Wiebe
2007 The Mathematical intelligencer  
Inroduction I report here on work done some years ago with Kurt Thomsen and Mark Wiebe, at the time undergraduate students at the University of Manitoba.  ...  The preceding remarks were the sort of thing that I showed Kurt Thomsen and Mark Wiebe back in 2001. They immediately embarrassed me by remarking that, of course, also 88 2 + 33 2 = 8833 .  ... 
doi:10.1007/bf02986204 fatcat:gn3xubzsbnh4pmrx44uz4jvbba

Monitoring Soil Moisture Dynamics Using Electrical Resistivity Tomography under Homogeneous Field Conditions

Steven M de Jong, Renée A Heijenk, Wiebe Nijland, Mark van der Meijde
2020 Sensors  
There is a gap between lab experiments where resistivity-soil moisture relations are generally very good and field studies in complex environmental settings where relations are always less good and complicated by many factors. An experiment was designed where environmental settings are more controlled, the best outside laboratory, to assess the transferability from lab to outdoor. A field experiment was carried out to evaluate the use of electric resistivity tomography (ERT) for monitoring soil
more » ... moisture dynamics over a period of 67 days. A homogeneous site in the central part of The Netherlands was selected consisting of grass pasture on an aeolian sand soil profile. ERT values were correlated to gravimetric soil moisture samples for five depths at three different dates. Correlations ranged from 0.43 to 0.73 and were best for a soil depth of 90 cm. Resistivity patterns over time (time-lapse ERT) were analyzed and related to rainfall events where rainfall infiltration patterns could be identified. Duplicate ERT measurements showed that the noise level of the instrument and measurements is low and generally below 3% for the soil profile below the mixed layer but above the groundwater. Although the majority of the measured resistivity patterns could be well explained, some artefacts and dynamics were more difficult to clarify, even so in this homogeneous field situation. The presence of an oak tree with its root structure and a ditch with surface water with higher conductivity may have an impact on the resistivity pattern in the soil profile and over time. We conclude that ERT allows for detailed spatial measurement of local soil moisture dynamics resulting from precipitation although field experiments do not yield accuracies similar to laboratory experiments. ERT approaches are suitable for detailed spatial analyses where probe or sample-based methods are limited in reach or repeatability.
doi:10.3390/s20185313 pmid:32957480 pmcid:PMC7570526 fatcat:4fyvsgxnlzfyjpxcvhnjyog42e

Knowledge and social laws

Wiebe van der Hoek, Mark Roberts, Michael Wooldridge
2005 Proceedings of the fourth international joint conference on Autonomous agents and multiagent systems - AAMAS '05  
In this paper we combine existing work in the area of social laws with a framework for reasoning about knowledge in multi-agent systems. The unifying framework in which this is done is based on Alternating-time Temporal Logic (ATL), to which semantics we add epistemic accessibility relations (to deal with the knowledge), actions (in order to naturally talk about allowed and forbidden actions) and updates (to model the effect of the implementation of the constraint in a social law). Apart from a
more » ... constraint, a social law has an objective: in our formalism, such objectives may refer to the knowledge that agents possess or do not possess. The result is a framework in which we can, for example, express that a desirable property (objective) of a social law is that one agent has the ability to bring about a certain type of knowledge in another agent, or that if one agent knows something, then it should behave in a certain way. We illustrate our approach with a case study, and we use model checking to demonstrate that properties of social laws with respect to this case study.
doi:10.1145/1082473.1082576 dblp:conf/atal/HoekRW05 fatcat:3ujmd2tx3rddtgycky32wwdrrq

Hypocellularity and absence of compaction as criteria for embryonic death

Donald W Landry, Howard A Zucker, Mark V Sauer, Michael Reznik, Lauren Wiebe
2006 Regenerative Medicine  
A precise definition of death is important for the appropriate application of medical resources and the harvesting of tissues for transplantation. For developed humans, life is considered to end when the criteria for brain death are met, but corresponding criteria are lacking for human embryos, and thus, we undertook a natural history study of embryonic death. Methods: De-identified records of the observations of human embryos in culture were analyzed retrospectively. The embryos were generated
more » ... by in vitro fertilization for the purpose of reproduction. Cell number and morphology were recorded on embryonic days 2, 3, 5, and 6. Viable embryos (n = 248) were compared to nonviable embryos (n = 444) and the latter were analyzed in subgroups defined by cell number and morphology. Results: Many nonviable embryos (n = 142 out of 444) were hypocellular and lacked compaction on embryonic day 5 (ED5). All of these hypocellular embryos did not progress to compacted morula or normal blastocyst when observed further. No criteria could be discerned for the diagnosis of death on ED3. Conclusions: Arrested development at the multicellular stage on ED5 indicates an irreversible loss of integrated organic function, and hence, the condition of death for the organism. Approximately a fifth of all embryos generated for in vitro fertilization -heretofore misclassified among the 'nonviable' -are in fact dead on ED5 by our criteria. We propose that the ethical framework currently used for obtaining essential organs from deceased persons for transplantation could be applied to the harvesting of live cells from dead human embryos for the creation of stem cells.
doi:10.2217/17460751.1.3.367 pmid:17465791 fatcat:s2h7ewpgrrg3fk2uge3dpntpmm

The Art of Cloaking Ownership: The Case of Sweden. By Gerard Aalders and Cees Wiebe · Amsterdam: Amsterdam University Press, 1996. vii + 210 pp. Notes, sources and index. $27.95. ISBN 90-5356-179-x

Mark Harrison
1996 Business History Review  
Mark Harrison Mark Harrison is Reader in Economics at the University of Warwick.  ...  The Aalders-Wiebes methodology is definitely a legal one: the step-by-step accumulation of an overwhelming mass of incriminating evidence both direct and circumstantial.  ... 
doi:10.2307/3117333 fatcat:iikrukf6iva7nnzetun7csah3a

Association of Depression and Treated Depression With Epilepsy and Seizure Outcomes

Colin B. Josephson, Mark Lowerison, Isabelle Vallerand, Tolulope T. Sajobi, Scott Patten, Nathalie Jette, Samuel Wiebe
2017 JAMA Neurology  
IMPORTANCE A bidirectional relationship exists between epilepsy and depression. However, any putative biological gradient between depression severity and the risk of epilepsy, and the degree to which depression mediates the influence of independent risk factors for epilepsy, has yet to be examined. OBJECTIVE To determine the effect of depression on the risk of epilepsy and seizure outcomes. DESIGN, SETTING, AND PARTICIPANTS An observational study of a population-based primary care cohort (all
more » ... tients free of prevalent depression and epilepsy at 18-90 years of age who were active after the Acceptable Mortality Reporting date in The Health Improvement Network database) and a prospectively collected tertiary care cohort (all patients whose data were prospectively collected from the Calgary Comprehensive Epilepsy Programme). The analyses were performed on March 16, 2016. MAIN OUTCOME AND MEASURES The hazard of developing epilepsy after incident depression and vice versa was calculated. In addition, a mediation analysis of the effect of depression on risk factors for epilepsy and the odds of seizure freedom stratified by the presence of depression were performed. RESULTS We identified 10 595 709 patients in The Health Improvement Network of whom 229 164 (2.2%) developed depression and 97 177 (0.9%) developed epilepsy. The median age was 44 years (interquartile range, 32-58 years) for those with depression and 56 years (interquartile range, 43-71 years) for those with epilepsy. Significantly more patients with depression (144 373 [63%] were women, and 84 791 [37%] were men; P < .001) or epilepsy (54 419 [56%] were women, and 42 758 [44%] were men; P < .001) were female. Incident epilepsy was associated with an increased hazard of developing depression (hazard ratio [HR], 2.04 [95% CI, 1.97-2.09]; P < .001), and incident depression was associated with an increased hazard of developing epilepsy (HR, 2.55 [95% CI, 2.49-2.60]; P < .001) There was an incremental hazard according to depression treatment type with lowest risk for those receiving counselling alone (HR, 1.84 [95% CI, 1.30-2.59]; P < .001), an intermediate risk for those receiving antidepressants alone (HR, 3.43 [95% CI, 3.37-3.47]; P < .001), and the highest risk for those receiving both (HR, 9.85 [95% CI,]; P < .001). Furthermore, depression mediated the relationship between sex, social deprivation, and Charlson Comorbidity Index with incident epilepsy, accounting for 4.6%, 7.1%, and 20.6% of the total effects of these explanatory variables, respectively. In the Comprehensive Epilepsy Programme, the odds of failing to achieve 1-year seizure freedom were significantly higher for those with depression or treated depression. CONCLUSIONS AND RELEVANCE Common underlying pathophysiological mechanisms may explain the risk of developing epilepsy following incident depression. Treated depression is associated with worse epilepsy outcomes, suggesting that this may be a surrogate for more severe depression and that severity of depression is associated with severity of epilepsy.
doi:10.1001/jamaneurol.2016.5042 pmid:28241168 pmcid:PMC5822203 fatcat:somfjgkwkrcp7pmslqatgulypa

Experimental quantum Hamiltonian learning

Jianwei Wang, Stefano Paesani, Raffaele Santagati, Sebastian Knauer, Antonio A. Gentile, Nathan Wiebe, Maurangelo Petruzzella, Jeremy L. O'Brien, John G. Rarity, Anthony Laing, Mark G. Thompson
2017 Nature Physics  
Efficiently characterising quantum systems, verifying operations of quantum devices and validating underpinning physical models, are central challenges for the development of quantum technologies and for our continued understanding of foundational physics. Machine-learning enhanced by quantum simulators has been proposed as a route to improve the computational cost of performing these studies. Here we interface two different quantum systems through a classical channel - a silicon-photonics
more » ... um simulator and an electron spin in a diamond nitrogen-vacancy centre - and use the former to learn the latter's Hamiltonian via Bayesian inference. We learn the salient Hamiltonian parameter with an uncertainty of approximately 10^-5. Furthermore, an observed saturation in the learning algorithm suggests deficiencies in the underlying Hamiltonian model, which we exploit to further improve the model itself. We go on to implement an interactive version of the protocol and experimentally show its ability to characterise the operation of the quantum photonic device. This work demonstrates powerful new quantum-enhanced techniques for investigating foundational physical models and characterising quantum technologies.
doi:10.1038/nphys4074 fatcat:k7tqfns2uzg57oqy6655w5sjfa

A systematic review on the effect of sweeteners on glycemic response and clinically relevant outcomes

Natasha Wiebe, Raj Padwal, Catherine Field, Seth Marks, Rene Jacobs, Marcello Tonelli
2011 BMC Medicine  
doi:10.1186/1741-7015-9-123 pmid:22093544 pmcid:PMC3286380 fatcat:ogzhvqesnzghdhknghnkbj2m64

Reovirus RNA recombination is sequence directed and generates internally deleted defective genome segments during passage [article]

Sydni C. Smith, Jennifer Gribble, Julia R. Diller, Michelle A. Wiebe, Timothy W. Thoner, Mark R. Denison, Kristen M. Ogden
2020 bioRxiv   pre-print
For viruses with segmented genomes, genetic diversity is generated by genetic drift, reassortment, and recombination. Recombination produces RNA populations distinct from full-length gene segments and can influence viral population dynamics, persistence, and host immune responses. Viruses in the Reoviridae family, including rotavirus and mammalian orthoreovirus (reovirus), have been reported to package segments containing rearrangements or internal deletions. Rotaviruses with RNA segments
more » ... ning rearrangements have been isolated from immunocompromised and immunocompetent children and in vitro following serial passage at high multiplicity. Reoviruses that package small, defective RNA segments have established chronic infections in cells and in mice. However, the mechanism and extent of Reoviridae RNA recombination are undefined. Towards filling this gap in knowledge, we determined the titers and RNA segment profiles for reovirus and rotavirus following serial passage in cultured cells. The viruses exhibited occasional titer reductions characteristic of interference. Reovirus strains frequently accumulated segments that retained 5′ and 3′ terminal sequences and featured large internal deletions, while similar segments were rarely detected in rotavirus populations. Using next-generation RNA-sequencing to analyze RNA molecules packaged in purified reovirus particles, we identified distinct recombination sites within individual viral gene segments. Recombination junction sites were frequently associated with short regions of identical sequence. Taken together, these findings suggest that reovirus accumulates defective gene segments featuring internal deletions during passage and undergoes sequence-directed recombination at distinct sites.
doi:10.1101/2020.10.19.346031 fatcat:qykriutxivco3ps5nfli2jwywa

Global Mapping of Seaport Operability Risk Indicators Using Open-Source Metocean Data

Matijs Wiegel, Wiebe de Boer, Mark van Koningsveld, Arne van der Hout, Ad Reniers
2021 Journal of Marine Science and Engineering  
Seaport operability is key to the economic viability of ports. Metocean conditions (e.g., wind, short waves, and infragravity waves) affect this operability when certain thresholds are exceeded. This paper describes a method for the global mapping of seaport operability risk indicators using open-source metocean data. This global-scale assessment provides a geographic overview of operability risks and first-order insights into the most relevant metocean risk indicators at each location. The
more » ... lts show that locations around the equator and inland seas have lower operability risk than locations farther away from the equator. "Hotspots" are mainly located along the southern capes (Cape of Good Hope, Leeuwin, Horn), around the 'Roaring Forties', and at exposed locations along the oceans. Of the metocean parameters considered, short waves are found to be the most critical risk indicator for port operability at most locations. Using (the insights of) this study, port authorities, operators, and designers can prepare for metocean risks at an early stage and effectively respond with mitigation measures and layout adjustments to improve port operability.
doi:10.3390/jmse9070695 fatcat:ggbdthaqrjggpohgibnhkb6wgq
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