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Fournier-Salaün and P. Fournier-Salaün / Central European Journal of Chemistry 5(4) 2007 1084-1093 M-C. Fournier-Salaün and P. ... Fournier-Salaün / Central European Journal of Chemistry 5(4) 2007 1084-1093 ...doi:10.2478/s11532-007-0038-4 fatcat:lrilb47of5ae5o4jkklcbck66a
This work is focused on the synthesis of organic carbonates from CO2 and ethanol. A parametric study of the synthesis of diethyl carbonate from ethanol is performed in a 100 mL batch reactor. The influence of pressure and temperature is studied and we prove that the presence of water strongly decreases the yield in diethyl carbonate as an equilibrium is quickly reached. One method to improve this yield is to remove water from the reaction mixture to shift the equilibrium toward the formation ofdoi:10.1515/gps-2019-0018 fatcat:cdfqkd5iobe5rambjk4pbravdy
more »... carbonates. The chemical methods give good results but separation and regeneration associated steps are prohibitive. For these reasons, a physical technique like pervaporation is chosen to remove water. The study of a pervaporation cell with membrane PERVAP 4100 gives good results for the dehydration of ethanol alone even at low concentrations of water from 0.33 %wt to 0.15 %wt. Twelve experiments on the dehydration of a mixture of ethanol, diethyl carbonate and water are performed. The calculated separation factors show a very good selectivity for water. That means that even in the presence of diethyl carbonate, the membrane has still a selective water permeability.
Marie-Christine MEUNIER-SALAÜN, Marie-Noëlle VANTRIMPONTE LN.R.A., Station de Recherches sur l'Elevage des Porcs, Saint-Gilles, 35590 L'Hermitage The effect of restricted space for growing-finishing ...doi:10.1051/animres:19850339 fatcat:tzw5yf25azburdnbexwjv2zmpi
L'importance du bien-être des animaux qui vivent sous la dépendance des humains (animaux d'élevage, de compagnie, de zoo, de cirque, d'expérimentation...) s'est affirmée progressivement au cours des 50 dernières années. Dans cette note, le concept de bien-être animal a été replacé dans ses contextes, philosophique, sociétal et juridique, qui influencent sa prise en compte et la signification qui lui est conférée. Une attention particulière a été portée aux bases scientifiques de la notion dedoi:10.20870/productions-animales.2018.31.2.2299 fatcat:go4c3jmkpfaezlbmzocnnqa7bu
more »... n-être, qui repose sur les caractéristiques psychiques des animaux, êtres sensibles et conscients. Notre définition du concept de bien-être est centrée sur l'état mental de l'individu dans son environnement et se démarque clairement du concept de bientraitance qui fait référence aux actions humaines positives envers les animaux, condition nécessaire au bien-être mais dont le résultat doit s'évaluer au niveau de l'animal. En outre, cette dimension mentale porte l'attention sur le fait qu'une bonne santé, un niveau de production satisfaisant ou une absence de stress ne suffisent pas. Il faut aussi prendre en compte ce que l'animal ressent, les perceptions subjectives déplaisantes, telles que la frustration, la douleur et la souffrance, mais aussi rechercher les signes d'expression d'émotions positives. Les protocoles d'évaluation du bien-être des animaux doivent ainsi combiner l'analyse des comportements et de l'état physiologique et sanitaire de l'animal avec les données sur l'environnement.
Feed intake behaviour traits were recorded on 210 Large White and 114 Pietrain entire male pigs housed in single-breed groups (range of group size: 8-13) and having 24 h access to 'Acema 48' electronic feed dispensers. Three stages of growth were considered (average body weights of 39, 64 and 89 kg for both breeds), and feeding behaviour traits were calculated separately for two periods of the day (8-20 h and 20-8 h). Slower-growing and leaner Pi6trains compared with Large Whites displayed adoi:10.1051/animres:19990402 fatcat:q3322owgh5gilfi4g6b2w5pct4
more »... h lower daily feed intake level ( 1.72 vs. 2.12 kg, P < 0.001) as well as a different feed intake pattern, consisting of much less feeder visits per day (8.8 vs. 15.7, P < 0.001 ), shorter daily eating time (49.7 vs. 55.6 min, P < 0.001 smaller daily number (5.84 vs. 6.53, P < 0.05) and average size (300 vs. 332 g, P < 0.05) of meals, and slower rate of feed intake (34.8 vs.
The sodium-hydrogen exchanger regulatory factor 1 (NHERF1) binds to the main renal phosphate transporter NPT2a and to the parathyroid hormone (PTH) receptor. We have recently identified mutations in NHERF1 that decrease renal phosphate reabsorption by increasing PTH-induced cAMP production in the renal proximal tubule. Methods: We compared relevant parameters of phosphate homeostasis in a patient with a previously undescribed mutation in NHERF1 and in control subjects. We expressed the mutantdoi:10.1371/journal.pone.0034764 pmid:22506049 pmcid:PMC3323571 fatcat:h7fxtptlybbszesrrbpf5eiegu
more »... ERF1 protein in Xenopus Oocytes and in cultured cells to study its effects on phosphate transport and PTH-induced cAMP production. Results: We identified in a patient with inappropriate renal phosphate reabsorption a previously unidentified mutation (E68A) located in the PDZ1 domain of NHERF1.We report the consequences of this mutation on NHERF1 function. E68A mutation did not modify cAMP production in the patient. PTH-induced cAMP synthesis and PKC activity were not altered by E68A mutation in renal cells in culture. In contrast to wild-type NHERF1, expression of the E68A mutant in Xenopus oocytes and in human cells failed to increase phosphate transport. Pull down experiments showed that E68A mutant did not interact with NPT2a, which robustly interacted with wild type NHERF1 and previously identified mutants. Biotinylation studies revealed that E68A mutant was unable to increase cell surface expression of NPT2a. Conclusions: Our results indicate that the PDZ1 domain is critical for NHERF1-NPT2a interaction in humans and for the control of NPT2a expression at the plasma membrane. Thus we have identified a new mechanism of renal phosphate loss and shown that different mutations in NHERF1 can alter renal phosphate reabsorption via distinct mechanisms.
Revised the paper before submission: David Val-Laillet, Marie-Christine Meunier-Salaün, Charles-Henri Malbert and Paul Meurice. ... Frontiers and designed the experiments: David Val-Laillet, Marie-Christine Meunier-Salaün and Caroline Clouard. Performed the experiments: Caroline Clouard. ...doi:10.3389/fpsyg.2014.00861 pmid:25147536 pmcid:PMC4124794 fatcat:ujn3sfrl7bcodi6oz6sjd7u4z4
et al., 2002; COURBOULAY, MEUNIER-SALÄUN et ROUS-SEAU, 2002) . ... ., 1984 ; MEUNIER-SALAÜN et al., 1987 ; VON BORELL et LADEWIG, 1989 ; JANSSENS et al., 1994) . ...doi:10.4267/2042/47833 fatcat:b73vzamk5bgzrgohyhjeesdtya
Future Science OA
Acknowledgments Thanks to Christine Herrencknecht for rereading the manuscript. ... E Rossignol, E Salaun and MB Amiand carried out the experiments. C Bobin-Dubigeon wrote the manuscript with support from E Rossignol and JM Bard. ...doi:10.2144/fsoa-2018-0113 pmid:31245038 pmcid:PMC6554689 fatcat:mxhv5f6cczg2jphjwuonuszubu
., 1997; Meunier-Salaün et al., 2001) and the improvement of voluntary feed intake during lactation (Matte et al., 1994; Farmer et al., 1996; Courboulay and Gaudré, 2002) . ...doi:10.1016/j.applanim.2006.12.007 fatcat:uoy7lzqekfcvtlygxevv66qpwq
Par ailleurs, en terme de conduite d'élevage, le logement des truites gestantes en groupes pose des problèmes particuliers concernant l'alimentation ou la gestion des lots d'animaux (MEUNIER-SALAÜN et ... Ces évolutions peuvent également entraîner un accroissement des coûts d'investissement et/ou de fonctionnement, qui peut pénaliser le coût de production et la compétitivité des élevages (GOURMELEN, SALAÜN ...doi:10.4267/2042/47835 fatcat:6z2gnbypvjgt7d6xbyx32pv3qm
Rearing social animals like pigs in isolation from conspecifics can have consequences on behaviour and physiology. The aim of this experiment was to determine whether rearing conditions affect body postures. We adapted a method for quantitative evaluation of postures based on geometric morphometrics, developed in horses, for pigs and applied it in different conditions. Forty eight 75-day old females were reared either alone in 2.25 m² pens (IH, N = 24 animals and 4 groups) or in groups of fourdoi:10.1016/j.applanim.2015.10.008 fatcat:ywuewd4x7jhhbfgwtgdg43ykay
more »... n 4.64 m² pens (GH, N = 24) for two weeks. They were habituated to human handling (stroking, speaking) and marking on their backs every day, and tested individually once a day for 10 min in a corridor outside the home pen during the two subsequent weeks. We observed their behaviour and posture during the first exposure to the test (novelty), and the fourth and fifth (after habituation). On the sixth and seventh tests, a familiar stockperson was present in the corridor (human presence). Before each test, the animals were marked with seven landmarks along their length, corresponding to anatomical points and easily located. An experimenter took pictures of the animals walking along the corridor, and these pictures were transferred to tps software for analysis. GH animals were more often active in the rearing pen than IH (median (IQ) 15% of observations [12-20%] versus 2% [0-13 %]; P < 0.05). All animals except one IH initiated contact with the handler during the last sessions of handling (Fisher's exact test, ns). Principal Component Analyses revealed significant effects of rearing and testing conditions on pigs' behaviour and posture. Novelty led to fewer vocalisations and more exploration for IH than GH animals (P < 0.05), but there were no differences between treatments after habituation to the testing situation. The backs of IH animals were more rounded than those of GH (P < 0.05; dimension 1 of PCA), independently of the test condition. Human presence had no effect on posture. Page 4 of 38 A c c e p t e d M a n u s c r i p t In conclusion, the method based on geometric morphometrics that we developed to study pig posture detected variations in walking posture in pigs associated with rearing conditions. Postures might reflect affective states in pigs, as shown in other species, but further studies are needed to verify this.
In animal husbandry, pigs have to cope with social challenges when regrouped with unfamiliar conspecifics. Regrouping pigs may result in an acute stress and physical injuries thus reducing animal welfare. The aim of the present experiment was to evaluate the behavioural, cortisol and growth responses of pigs to a repeated social stress. Thirty-two growing-finishing pigs were housed in pairs. Animals of half of the pairs were placed in a new pen with a new partner three times a week during 4doi:10.1016/j.applanim.2006.05.007 fatcat:kozalc5t2jfyneij74324qijvm
more »... s (R pigs, n = 8 pairs). Other animals stayed in the same pen with the same partner (C pigs, n = 8 pairs). During the first 90 min following each regrouping, vigorous fights were frequent in R pigs. Those pigs exhibited more agonistic behaviour than C pigs throughout the experiment (P < 0.05). The number of offensive acts realized by R pigs decreased throughout the experiment (P < 0.05) whereas the number of defensive acts did not vary (P > 0.1). The time-budget determined during 24 h 2 days after the third, sixth, ninth and 12th regrouping was similar in R and C pigs except the percentage of standing that was higher in R pigs after the last regrouping. R pigs tended to have a lower daily liveweight gain at the fifth regrouping (P = 0.07). Salivary cortisol concentrations were higher in R than in C pigs 4-5 h after the second and fifth regrouping (P < 0.05) but were similar in both groups after the ninth and 11th regrouping. Basal cortisol measured 2 days after the last regrouping in plasma and saliva was higher in R than C pigs. In response to a dexamethasone/ACTH challenge, cortisol in saliva and plasma was similar in both groups (P > 0.05). The behavioural and cortisol responses to regrouping and relocation in pigs decreased over time but were www.elsevier.com/locate/applanim Applied Animal Behaviour Science 105 (2007) 102-114
., Meunier-Salaün, M.-C., Tallet, C. (2019). ... ., Meunier-Salaün, M.-C., Tallet, C. (2019). ...doi:10.1016/j.applanim.2018.10.009 fatcat:mrgwdufcl5hldnjwyrp56p36mu
This study investigated the behavioural and brain responses towards conditioned flavours with different hedonic values in juvenile pigs. Twelve 30-kg pigs were given four three-day conditioning sessions: they received three different flavoured meals paired with intraduodenal (i.d.) infusions of 15% glucose (F Glu ), lithium chloride (F LiCl ), or saline (control treatment, F NaCl ). One and five weeks later, the animals were subjected to three two-choice feeding tests without reinforcement todoi:10.1371/journal.pone.0037968 pmid:22685528 pmcid:PMC3368353 fatcat:lirifsk7nfgclb7cu7emwpdlpe
more »... eck the acquisition of a conditioned flavour preference or aversion. In between, the anaesthetised pigs were subjected to three 18 FDG PET brain imaging coupled with an olfactogustatory stimulation with the conditioned flavours. During conditioning, the pigs spent more time lying inactive, and investigated their environment less after the F LiCl than the F NaCl or F Glu meals. During the two-choice tests performed one and five weeks later, the F NaCl and F Glu foods were significantly preferred over the F LICl food even in the absence of i.d. infusions. Surprisingly, the F NaCl food was also preferred over the F Glu food during the first test only, suggesting that, while LiCl i.d. infusions led to a strong flavour aversion, glucose infusions failed to induce flavour preference. As for brain imaging results, exposure to aversive or less preferred flavours triggered global deactivation of the prefrontal cortex, specific activation of the posterior cingulate cortex, as well as asymmetric brain responses in the basal nuclei and the temporal gyrus. In conclusion, postingestive visceral stimuli can modulate the flavour/ food hedonism and further feeding choices. Exposure to flavours with different hedonic values induced metabolism differences in neural circuits known to be involved in humans in the characterization of food palatability, feeding motivation, reward expectation, and more generally in the regulation of food intake.
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