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Apolipoprotein E and alpha brain rhythms in mild cognitive impairment: A multicentric Electroencephalogram study

Claudio Babiloni, Luisa Benussi, Giuliano Binetti, Emanuele Cassetta, Gloria Dal Forno, Claudio Del Percio, Florinda Ferreri, Raffaele Ferri, Giovanni Frisoni, Roberta Ghidoni, Carlo Miniussi, Guido Rodriguez (+4 others)
2006 Annals of Neurology  
The present multicentric EEG study tested the hypothesis that presence of 4 affects sources of resting EEG rhythms in both MCI and AD subjects.  ...  Interpretation: Such a demonstration motivates future genotype-EEG phenotype studies for the early prediction of AD conversion in individual MCI subjects.  ...  The present EEG study tested the hypothesis that the ApoE ε4 allele affects cortical sources of resting EEG rhythms in MCI.  ... 
doi:10.1002/ana.20724 pmid:16358334 fatcat:ab42ipw3nzbyjnzdhw6spkmvcy

Occipital sources of resting-state alpha rhythms are related to local gray matter density in subjects with amnesic mild cognitive impairment and Alzheimer's disease

Claudio Babiloni, Claudio Del Percio, Marina Boccardi, Roberta Lizio, Susanna Lopez, Filippo Carducci, Nicola Marzano, Andrea Soricelli, Raffaele Ferri, Antonio Ivano Triggiani, Annapaola Prestia, Serenella Salinari (+11 others)
2015 Neurobiology of Aging  
Occipital sources of resting-state electroencephalographic (EEG) alpha rhythms are abnormal, at the group level, in patients with amnesic mild cognitive impairment (MCI) and Alzheimer's disease (AD).  ...  EEG cortical sources were estimated by low-resolution brain electromagnetic tomography.  ...  (EEG) alpha rhythms are abnormal, at the group level, in patients with amnesic mild cognitive impairment (MCI) and Alzheimer's disease (AD).  ... 
doi:10.1016/j.neurobiolaging.2014.09.011 pmid:25442118 pmcid:PMC4315728 fatcat:ikfartq5gfgnlnj6wbyroz3bhq

Resting State Cortical Electroencephalographic Rhythms in Alzheimer`s Disease

Claudio Babiloni, Fabrizio Vecchio, Roberta Lizio, Giovanni B. Frisoni, Raffaele Ferri, Guido Rodriguez, Paolo M. Rossini
2010 The Open Nuclear Medicine Journal  
Oscillatory electromagnetic brain activity is a hallmark of neuronal network function in various brain regions.  ...  However, age is the main risk factor for neurodegenerative disorders such as Alzheimer's disease (AD) that impact on cognition.  ...  Roberta Lizio carried out this research in the framework of Doctoral School on "Neurophysiology" at the Department of Physiology and Pharmacology, University of Rome Sapienza -Italy.  ... 
doi:10.2174/1876388x01002010063 fatcat:z2cgswco3ffllkhc5seierzv2a

Sources of cortical rhythms in adults during physiological aging: A multicentric EEG study

Claudio Babiloni, Giuliano Binetti, Andrea Cassarino, Gloria Dal Forno, Claudio Del Percio, Florinda Ferreri, Raffaele Ferri, Giovanni Frisoni, Silvana Galderisi, Koichi Hirata, Bartolo Lanuzza, Carlo Miniussi (+5 others)
2006 Human Brain Mapping  
This electroencephalographic (EEG) study tested whether cortical EEG rhythms (especially delta and alpha) show a progressive increasing or decreasing trend across physiological aging.  ...  To this aim, we analyzed the type of correlation (linear and nonlinear) between cortical EEG rhythms and age.  ...  The previous study aimed at analyzing (1) the distributed EEG sources specific to mild Alzheimer's disease (AD) as compared to vascular dementia (VaD) or normal aging; and (2) the sensitivity of these  ... 
doi:10.1002/hbm.20175 pmid:16108018 fatcat:gqwme5se25emho5md62f5jycmq

Ibuprofen treatment modifies cortical sources of EEG rhythms in mild Alzheimer's disease

Claudio Babiloni, Giovanni B. Frisoni, Claudio Del Percio, Orazio Zanetti, Cristina Bonomini, Emanuele Cassetta, Patrizio Pasqualetti, Carlo Miniussi, Mario De Rosas, Anna Valenzano, Giuseppe Cibelli, Fabrizio Eusebi (+1 others)
2009 Clinical Neurophysiology  
Here we evaluated the hypothesis that long-term ibuprofen treatment affects cortical sources of resting electroencephalographic (EEG) rhythms in mild AD patients.  ...  Objective: Non-steroidal anti-inflammatory drugs such as ibuprofen have a protective role on risk of Alzheimer's disease (AD).  ...  We also thank Angelini SpA and Astra-Zeneca Pharmaceuticals for the supply of active drug tablets and relative placebo.  ... 
doi:10.1016/j.clinph.2009.02.005 pmid:19324592 fatcat:y2tnla4skvfunkgl6shi6wvlim

What Electrophysiology Tells Us About Alzheimer's Disease: A Window into the Synchronization and Connectivity of Brain Neurons

Claudio Babiloni, Katarzyna Blinowska, Laura Bonanni, Andrej Cichocki, Willem De Haan, Claudio del Percio, Bruno Dubois, Javier Escudero, Alberto Fernández, Giovanni Frisoni, Bahar Guntekin, Mihaly Hajos (+29 others)
2019 Neurobiology of Aging  
However, current international guidelines do not endorse the use of electroencephalographic (EEG)/magnetoencephalographic (MEG) biomarkers in clinical trials performed in patients with Alzheimer's disease  ...  Converging evidence shows relationships between abnormalities in EEG/MEG markers and cognitive deficits in groups of AD patients at different disease stages.  ...  Resting state EEG/MEG rhythms in AD at the group level EEG Amplitude or source activity of resting state eyes-closed cortical EEG rhythms probes the mechanisms of synchronization/desynchronization of  ... 
doi:10.1016/j.neurobiolaging.2019.09.008 pmid:31739167 fatcat:4qovqzkklfduvane3tuttfnfem

Two-Year Longitudinal Monitoring of Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer's Disease Using Topographical Biomarkers Derived from Functional Magnetic Resonance Imaging and Electroencephalographic Activity

Jorge Jovicich, Claudio Babiloni, Clarissa Ferrari, Moira Marizzoni, Davide V. Moretti, Claudio Del Percio, Roberta Lizio, Susanna Lopez, Samantha Galluzzi, Diego Albani, Libera Cavaliere, Ludovico Minati (+25 others)
2018 Journal of Alzheimer's Disease  
functional biomarkers of prodromal Alzheimer's disease (AD).  ...  rhythms and decreased source activity at low-frequency alpha (8-10.5 Hz) rhythms; and 3) reduced parietal and posterior cingulate source activities of aoERPs.  ...  This article is part of a Mini Forum on PharmaCog matrix of biomarkers of prodromal AD in patients with aMCI, which is based on four papers published in the Journal of Alzheimer's Disease.  ... 
doi:10.3233/jad-180158 pmid:30400088 fatcat:j7vzqy7575ghlequk2n77ka4q4

Abnormalities of Cortical Neural Synchronization Mechanisms in Subjects with Mild Cognitive Impairment due to Alzheimer's and Parkinson's Diseases: An EEG Study

Claudio Babiloni, Claudio Del Percio, Roberta Lizio, Giuseppe Noce, Susanna Cordone, Susanna Lopez, Andrea Soricelli, Raffaele Ferri, Maria Teresa Pascarelli, Flavio Nobili, Dario Arnaldi, Francesco Famà (+27 others)
2017 Journal of Alzheimer's Disease  
U n c o r r e c t e d A u t h o r P r o o f Journal of Alzheimer's Disease xx (20xx) x-xx  ...  Clin Neurophysiol 117, 2521-2531. [75] Stoffers D, Bosboom JLW, Wolters ECh, Berendse HW, disease individuals from cortical sources of resting state EEG rhythms.  ...  group as a control referin the distribution of the eLORETA source solutions.  ... 
doi:10.3233/jad-160883 pmid:28621693 fatcat:if5wdlyljzdj5e5ve3dp6ahda4

ABNORMALITIES OF CORTICAL NEURAL SYNCHRONIZATION MECHANISMS IN SUBJECTS WITH MILD COGNITIVE IMPAIRMENT DUE TO ALZHEIMER'S AND PARKINSON'S DISEASES: AN EEG STUDY

Roberta Lizio, Claudio Del Percio, Susanna Cordone, Susanna Lopez, Andrea Soricelli, Raffaele Ferri, Flavio Nobili, Francesco Famà, Dag Aarsland, Francesco Orzi, Carla Buttinelli, Franco Giubilei (+16 others)
2017 Alzheimer's & Dementia  
The aim of this retrospective and exploratory study was that the cortical sources of resting state eyes-closed electroencephalographic (rsEEG) rhythms might reveal different abnormalities in cortical neural  ...  synchronization in groups of patients with mild cognitive impairment due to Alzheimer's disease (ADMCI) and Parkinson's disease (PDMCI) as compared to healthy subjects.  ...  with mild cognitive impairment due to Alzheimer's disease (ADMCI) and Parkinson's disease (PDMCI) and education.  ... 
doi:10.1016/j.jalz.2017.06.1411 fatcat:ljijnyhblrhkznkiuk7ljo5vae

Magnetoencephalography

Malcolm Proudfoot, Mark W Woolrich, Anna C Nobre, Martin R Turner
2014 Practical Neurology  
MRT conceived and edited the manuscript, and is guarantor of the content.  ...  , in a study of a small number of subjects with minimal cognitive impairment. 39 A larger (117 Alzheimer's disease subjects) multicentre MEG study was subsequently performed; 1 min of resting-state data  ...  MEG data reconstructed into source space (B) with a beamformer approach and presented on a 3D cortical map.  ... 
doi:10.1136/practneurol-2013-000768 pmid:24647614 pmcid:PMC4174130 fatcat:yqi7ch4c2rcqvpwn6tnpct3nuu

Measuring Cortical Connectivity in Alzheimer's Disease as a Brain Neural Network Pathology: Toward Clinical Applications

Stefan Teipel, Michel J. Grothe, Juan Zhou, Jorge Sepulcre, Martin Dyrba, Christian Sorg, Claudio Babiloni
2016 Journal of the International Neuropsychological Society  
and neurophysiological substrates of Alzheimer's disease (AD) as a brain neural network pathology affecting structural and functional cortical connectivity underlying human cognition.Methods:We reviewed  ...  mode and attention-related networks; and (3) abnormal power and functional coupling of resting state cortical EEG rhythms.  ...  (EEG) techniques prevents a reliable and precise spatial estimation of the cortical sources and of the functional coupling of the EEG rhythms.  ... 
doi:10.1017/s1355617715000995 pmid:26888613 fatcat:ugywcnr6grbbvfmme5l6tzuwqi

Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology

Harald Hampel, Nicola Toschi, Claudio Babiloni, Filippo Baldacci, Keith L. Black, Arun L.W. Bokde, René S. Bun, Francesco Cacciola, Enrica Cavedo, Patrizia A. Chiesa, Olivier Colliot, Cristina-Maria Coman (+32 others)
2018 Journal of Alzheimer's Disease  
The Precision Neurology development process implements systems theory with system biology and neurophysiology in a parallel, bidirectional research path: a combined hypothesis-driven investigation of systems  ...  different diseases and subgroups at different stages of pathophysiological progression.  ...  DBS of the nucleus basalis of Meynert was studied in six patients with mild to moderate AD in a 12-month pilot study [413] .  ... 
doi:10.3233/jad-179932 pmid:29562524 pmcid:PMC6008221 fatcat:j3u6gkzfqbg47kv4o2hpkjadn4

172. Tagung der Schweizerischen Neurologischen Gesellschaft / 172e Réunion de la Société Suisse de Neurologie und/et Annual meeting of the Swiss Society for Sleep Research, Sleep Medicine and Chronobiology (Zürich, 20.-22. November 2003)

2004 Swiss Archives of Neurology and Psychiatry  
This study investigated the mechanism of stroke in ICAD by examining brain imaging and cerebrovascular findings of such patients.  ...  Night-time BP dipping is defined by a ratio of night-time/daytime mean systolic BP values of <0.9. Results: We evaluated 15 patients with a mean age of 64 years (range 44-83).  ...  Cognitive performance, behavioural and psychological symptoms and circadian rhythm disturbances in Alzheimer's disease patients treated with quetiapine or haloperidol C. Schröder a , C.  ... 
doi:10.4414/sanp.2004.01463 fatcat:djhk3r5qwzdexnfadxok53k3wa

Brain imaging and human nutrition: which measures to use in intervention studies?

Stéphane V. Sizonenko, Claudio Babiloni, Eveline A. de Bruin, Elizabeth B. Isaacs, Lena S. Jönsson, David O. Kennedy, Marie E. Latulippe, M. Hasan Mohajeri, Judith Moreines, Pietro Pietrini, Kristine B. Walhovd, Robert J. Winwood (+1 others)
2013 British Journal of Nutrition  
Acknowledgements Acknowledgements The present study was conducted by an expert group of the European Branch of the ILSI (ILSI Europe).  ...  This paper was published as a supplement to British Journal of Nutrition, publication of which was supported by ILSI Europe.  ...  (c, d) Topographic maps showing cortical sources of the ERD at a (about 10 Hz) and b (about 20 Hz) frequencies.  ... 
doi:10.1017/s0007114513001384 pmid:23902645 fatcat:4pz4tae7xrh7vlarhc7z3jv7wm

VII Congresso Sindem: Italian Association for the study of Dementia linked to the Italian Neurological Society (SIN)

Vincenzo Bonavita, Carlo Caltagirone, Claudio Mariani, Alessandro Padovani, Elio Scarpini, Sandro Sorbi, Daniela Galimberti
2012 Journal of Alzheimer's Disease  
Abstracts 43 Diffusion MRI Since the fi rst applications to AD, DT-MRI has shown the ability to detect microscopic WM abnormalities (FA and MD changes), mainly in the corpus callosum, temporal, frontal  ...  Perfusion SPECT with 99 Tc-ethylene cystine dimer showed hypoperfusion in the frontotemporal Abstracts 64 Aim: To map the distributed sources of cortical EEG rhythms in LBD respect to AD.  ...  Conclusions: In LBD, the delta source of cortical EEG rhythms in parieto-occipital regions could be related to a "functional lesion" in regions processing visuo-spatial information.  ... 
doi:10.3233/jad-2012-129000 pmid:22398403 fatcat:zebkyxd3zzat7gsq4vu3eq7zci
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