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Advances in optical mapping for genomic research

Yuxuan Yuan, Claire Yik-Lok Chung, Ting-Fung Chan
2020 Computational and Structural Biotechnology Journal  
Optical mapping also enables genome comparison and identification of large-scale structural variations.  ...  Recent advances in optical mapping have allowed the construction of improved genome assemblies with greater contiguity.  ...  Another cross-platform software is BioNanoAnalyst, which visualizes mis-assemblies as conflicts between sequence and optical map assemblies [76] .  ... 
doi:10.1016/j.csbj.2020.07.018 pmid:32802277 pmcid:PMC7419273 fatcat:j7pbytromndbnbr6vxp7vjzvqq