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Malaria's Missing Number: Calculating the Human Component of R0 by a Within-Host Mechanistic Model of Plasmodium falciparum Infection and Transmission

Geoffrey L. Johnston, David L. Smith, David A. Fidock, Rustom Antia
2013 PLoS Computational Biology  
Citation: Johnston GL, Smith DL, Fidock DA (2013) Malaria's Missing Number: Calculating the Human Component of R 0 by a Within-Host Mechanistic Model of Plasmodium falciparum Infection and Transmission  ...  Here, we describe a mechanistic within-host model of Plasmodium falciparum infection in humans and pathogen transmission to the mosquito vector.  ...  Acknowledgments Computing resources were provided in part by the 'Hotfoot' High Performance Computing Cluster at Columbia University. Author Contributions  ... 
doi:10.1371/journal.pcbi.1003025 pmid:23637586 pmcid:PMC3630126 fatcat:ldopuulw2zagznrmwcyquwcg5q

Mathematical modelling and analysis to understand interventions against malaria in humans

Flavia Camponovo
2021
Smith, and D. A. Fidock, "Malaria's Missing Number: Calculating the Human Component of R0 by a Within-Host Mechanistic Model of Plasmodium falciparum Infection and Transmission," PLoS Comput.  ...  minmedian and max of the nine summary statistics as well as duration o infection (more details in This transmission model was used to understand the human component of the reproductive number R0, and  ...  Maurer's cleft A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable  ... 
doi:10.5451/unibas-ep83175 fatcat:v6u4rkhglnfqzaru2cfbfihfhe