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MT-Flow – An Environment for Workflow-Supported Model Transformations in MDA [chapter]

Jernej Kovse, Theo Härder
2004 Lecture Notes in Computer Science  
and (ii) a set of domain-specific templates for model transformations.  ...  In this paper, we show that efficient composition of system specifications (which, in our case, are expressed as models) is also possible using (i) a domain-specific workflow model that guides the composition  ...  We will try to explore this relation and support it in the implementation of MT-Flow.  ... 
doi:10.1007/978-3-540-25975-6_13 fatcat:mpytfjr5zfgd3aqmowenjzktba

Apie taikomųjų programų sąveikumo metodologiją, grindžiamą giluminėmis žiniomis

Andrius Valatavičius, Saulius Gudas
2018 Informacijos mokslai  
Modifikuota MDA schema leidžia apibrėžti organizacijos veiklos srities realybės priežastinius ryšius ir juos perduoti į skirtingus MDA sluoksnių modelius.  ...  Siūlomo metodo metodologinis pagrindas yra vidinio modeliavimo paradigma, kuri integruota su MDA (OMG) metodu.  ...  For this purpose, the agent must understand domain environment and have an internal model of this environment.  ... 
doi:10.15388/im.2017.79.11400 fatcat:inx7y3qf6bhwnozmc2wk2hwpie

A Proposed Compiler to Integrate Model Driven Architecture with Web Services Road Map

Mohammed Abdalla Osman Mukhtar, Azween Abdullah, Alan G. Downe
2011 International Journal of Computer Applications  
This solution will provide valuable contribution especially for MDA infrastructure, firstly to eliminate repository requirements for target model, secondly to make model transformation as web services.  ...  Model Driven Architecture (MDA) technique is mainly depend on two processes; mapping specification and transformation definition, this last one (sometimes called model transformation definition) has a  ...  QVT RELATIONAL LANGUAGE QVT is the OMG standard language for specifying model transformations in the context of MDA.  ... 
doi:10.5120/1964-2630 fatcat:4xqpv22h3rcd5g27wgdqsh6khq

Causal Modelling in Enterprise Architecture Frameworks

Saulius Gudas
2021 Informatica  
Strategic Viewpoint (StV) modelling using causal meta-models is described in detail and illustrated in the case study.  ...  Two levels of the enterprise causal modelling were obtained. The first level uses the Management Transaction (MT) framework.  ...  The rules for transformation of the Domain Knowledge Model (DKM) to StV viewpoint meta-models are presented in Table 4 .  ... 
doi:10.15388/21-infor446 fatcat:aoe3czzwbjaq5ha2pvnsw5hfwe

Managing the quality of software product line architectures through reusable model transformations

Amogh Kavimandan, Aniruddha Gokhale, Gabor Karsai, Jeff Gray
2011 Proceedings of the joint ACM SIGSOFT conference -- QoSA and ACM SIGSOFT symposium -- ISARCS on Quality of software architectures -- QoSA and architecting critical systems -- ISARCS - QoSA-ISARCS '11  
However, limited support for reuse in contemporary model transformation techniques forces developers of product line architectures to reinvent transformation rules for every variant of the product line  ...  The paper uses two product line case studies to evaluate MTS in terms of reduction in efforts to define model transformation rules as new variants are added to the product line, and the overhead in executing  ...  CONCLUSIONS This paper presented MTS (Model-transformation Templatization and Specialization) that seamlessly integrates with an existing model transformation tool to support reusable model transformations  ... 
doi:10.1145/2000259.2000264 dblp:conf/qosa/KavimandanGKG11 fatcat:zhbkwuqnrrcjhluuejrsyrzhwq

Model Driven Engineering: An Emerging Technical Space [chapter]

Jean Bézivin
2006 Lecture Notes in Computer Science  
As an emerging solution to the handling of complex and evolving software systems, Model Driven Engineering (MDE) is still very much in evolution.  ...  Various organizations and companies (OMG, IBM, Microsoft, etc.) are currently proposing several environments claiming to support MDE.  ...  This work has been supported in part by the IST European project "ModelWare" (contract 511731).  ... 
doi:10.1007/11877028_2 fatcat:uckb3nqyvnbtfetrxzbst7a7qi

Image Beyond A Standardized Workflow For Geothermal Exploration (D2.05)

IMAGE Consortium
2017 Zenodo  
A multidisciplinary geothermal exploration approach, based on state-of-the-art scientific methods and integrated in industry workflows, has been key to advancement.  ...  IMAGE main aim has been to develop exploration methods for an extended resource base, including supercritical and deep basement/sedimentary geothermal reservoirs.  ...  A 3D geological model was made and used as basis for thermal, mechanical and ground water flow models. These models helped us to define the exploration workflow performed in the project.  ... 
doi:10.5281/zenodo.1255213 fatcat:6w3f72fm6ffqxnnzdgmgirqn6u

Survey and classification of model transformation tools

Nafiseh Kahani, Mojtaba Bagherzadeh, James R. Cordy, Juergen Dingel, Daniel Varró
2018 Journal of Software and Systems Modeling  
In this paper, we compare and evaluate the current model transformation tools based on a qualitative framework.  ...  An impressive number of model transformation languages and associated tools have been developed over the last few years.  ...  We also thank the anonymous reviewers for their valuable comments and suggestions in improving this report.  ... 
doi:10.1007/s10270-018-0665-6 fatcat:xo2spo3qynf5bnulmei3hioczi

A Process Model for Component-Based Model-Driven Software Development

Afrah Umran Alrubaee, Deniz Cetinkaya, Gernot Liebchen, Huseyin Dogan
2020 Information  
The model is successfully tested by applying it to the development of an e-learning system as an exemplar case study.  ...  There are many research studies that show the benefits of using software components and model-driven approaches. However, in many cases the development process is either ad-hoc or not well-defined.  ...  language); pl is a programming language for final code generation; MTP is a set of formal model transformation patterns; STP is a set of other supplementary model transformation patterns; MT is a set  ... 
doi:10.3390/info11060302 fatcat:elgoxu5jcvbubb52tdk5sk35eu

Robotic Software Systems: From Code-Driven to Model-Driven Software Development [chapter]

Christian Schlegel, Andreas Steck, Alex Lotz
2012 Robotic Systems - Applications, Control and Programming  
Introduction Advances in robotics and cognitive sciences have stimulated expectations for emergence of new generations of robotic devices that interact and cooperate with people in ordinary human environments  ...  Despite the expended effort, even sophisticated systems are still not able to perform at an expected and appropriate level of overall quality of service in complex scenarios in real-world environments.  ...  Two step transformation workflow: Framework Builder view. (M2M) transformation (encoded with Xtend)f r o mt h ePIM into a Platform Specific Model (PSM).  ... 
doi:10.5772/25896 fatcat:7fwavvcrg5hcva7tp7n7ifshru

Modulated TRPC1 expression predicts sensitivity of breast cancer to doxorubicin and magnetic field therapy: segue towards a precision medicine approach [article]

Yee Kit Tai, Karen Ka Wing Chan, Charlene Hui Hua Fong, Sharanya Ramanan, Jasmine Lye Yee Yap, Jocelyn Naixin Yin, Yun Sheng Yip, Wei Ren Tan, Angele Pei Fern Koh, Nguan Soon Tan, Ching Wan Chan, Ruby Yun Ju Huang (+1 others)
2021 bioRxiv   pre-print
role of PEMF-therapy as an effective companion therapy to DOX-based chemotherapy for the treatment of breast cancers characterized by elevated TRPC1 expression levels.  ...  Synergism could be corroborated in vivo with patient-derived xenograft mouse models, wherein PEMF exposure alone or in combination with DOX reduced tumor size.  ...  Acknowledgments The authors acknowledge Zac Goh (iHealthtech, National University of Singapore) for the design of the graphical abstract of the CAM model in Fig. 2 and the animal model in Fig. 4 We  ... 
doi:10.1101/2021.04.30.442085 fatcat:bhvpwyyjabhobo7hz6w5zytare

Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach

Yee Kit Tai, Karen Ka Wing Chan, Charlene Hui Hua Fong, Sharanya Ramanan, Jasmine Lye Yee Yap, Jocelyn Naixin Yin, Yun Sheng Yip, Wei Ren Tan, Angele Pei Fern Koh, Nguan Soon Tan, Ching Wan Chan, Ruby Yun Ju Huang (+3 others)
2022 Frontiers in Oncology  
for the use of PEMF-based therapies as an adjuvant to DOX chemotherapy for the treatment of breast cancers characterized by elevated TRPC1 expression levels.  ...  In this study, potential synergism between doxorubicin (DOX) and pulsed electromagnetic field (PEMF) therapy was investigated in: 1) MCF-7 and MDA-MB-231 cells in vitro; 2) MCF-7 tumors implanted onto  ...  The authors would like to acknowledge Zac Goh (iHealthtech, National University of Singapore) for the design of the animal model illustration in Figure 1A , CAM model illustration in  ... 
doi:10.3389/fonc.2021.783803 pmid:35141145 pmcid:PMC8818958 fatcat:raxtsrrmqvf5xc46s7zdhyssde

Bioanalytical and Mass Spectrometric Methods for Aldehyde Profiling in Biological Fluids

Romel P. Dator, Morwena J. Solivio, Peter W. Villalta, Silvia Balbo
2019 Toxics  
including recent advances in mass spectrometry (MS)-based profiling methods for identifying potential biomarkers of aldehyde exposure.  ...  In addition, we present emerging mass spectrometry-based methods, which use high-resolution accurate mass (HR/AM) analysis for characterizing carbonyl compounds and their potential applications in molecular  ...  (PH) for the analysis of MDA in plasma and rat liver microsomes [190] ; pentafluorophenyl hydrazine (PFPH) for the analysis of carbonyls in MTS [23] ; 2,3-diaminonaphthalene along with salting-out assisted  ... 
doi:10.3390/toxics7020032 pmid:31167424 pmcid:PMC6630274 fatcat:azgfl6e52fcwtdndkwxg7f3soe

An Executable Model Driven Framework for Enterprise Architecture Application to the Smart Grids Context

Rachida Seghiri, Frederic Boulanger, Claire Lecocq, Vincent Godefroy
2016 2016 49th Hawaii International Conference on System Sciences (HICSS)  
Therefore, our framework enables stakeholders to validate and criticize their modeling choices for the EA in the context of Smart Grids.  ...  We propose a framework that allows for modeling Enterprise Architectures (EA) in order to automate analysis, prediction, simulation, and thus to address the key issue of business/IT alignment.  ...  The model m A is typed by MT A , and a model transformation t A è C transforms m A into m C .  ... 
doi:10.1109/hicss.2016.565 dblp:conf/hicss/SeghiriBLG16 fatcat:noacr6jd5jasbczo7yckbjhqoy

Complexome Profiling—Exploring Mitochondrial Protein Complexes in Health and Disease

Alfredo Cabrera-Orefice, Alisa Potter, Felix Evers, Johannes F. Hevler, Sergio Guerrero-Castillo
2022 Frontiers in Cell and Developmental Biology  
Besides, complexome profiling has been utilized to study the dynamics of OXPHOS complexes, as well as the impact of an increasing number of mutations leading to mitochondrial disorders or rearrangements  ...  species but also to identify novel protein interactors involved in their assembly, maintenance and functions.  ...  Ulrich Brandt for carefully revising this manuscript and helpful suggestions.  ... 
doi:10.3389/fcell.2021.796128 pmid:35096826 pmcid:PMC8790184 fatcat:j3tbfy3bofervn5f4hsnvwh33q
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