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MRI plaque imaging reveals high-risk carotid plaques especially in diabetic patients irrespective of the degree of stenosis

L Esposito, T Saam, P Heider, Angelina Bockelbrink, Jaroslav Pelisek, D Sepp, R Feurer, C Winkler, T Liebig, K Holzer, O Pauly, S Sadikovic (+2 others)
2010 BMC Medical Imaging  
Conclusion: DM 2 seems to represent a predictor for the development of vulnerable carotid plaques irrespective of the degree of stenosis and other risk factors.  ...  This study investigates whether MRI-plaque imaging can reveal differences in carotid plaque features of diabetic patients compared to nondiabetics.  ...  to play a role in the development of high-risk, rupture prone plaques irrespective of the degree of vessel narrowing.  ... 
doi:10.1186/1471-2342-10-27 pmid:21118504 pmcid:PMC3004802 fatcat:vjixtg6ajna5td7debk6u7b3a4

Prediction of Stroke Risk by Detection of Hemorrhage in Carotid Plaques

Andreas Schindler, Regina Schinner, Nishaf Altaf, Akram A. Hosseini, Richard J. Simpson, Lorena Esposito-Bauer, Navneet Singh, Robert M. Kwee, Yoshitaka Kurosaki, Sen Yamagata, Kazumichi Yoshida, Susumu Miyamoto (+7 others)
2019 JACC Cardiovascular Imaging  
IPH in carotid stenosis increases the risk of cerebrovascular events.  ...  The goal of this study was to compare the risk of stroke between patients with carotid artery disease with and without the presence of intraplaque hemorrhage (IPH) on magnetic resonance imaging.  ...  Detection of IPH by using MRI is common and associated with an increased risk of future stroke in patients with symptomatic carotid stenosis irrespective of the degree of luminal narrowing, as well as  ... 
doi:10.1016/j.jcmg.2019.03.028 pmid:31202755 fatcat:aow4dy2fzfdztibde3pk4jelsq

Carotid endarterectomy for symptomatic low-grade carotid stenosis

Enzo Ballotta, Annalisa Angelini, Franco Mazzalai, Giacomo Piatto, Antonio Toniato, Claudio Baracchini
2014 Journal of Vascular Surgery  
Plaque instability seems to play a major part in the onset of ischemic events, regardless the entity of lumen narrowing. (J Vasc Surg 2014;59:25-31.)  ...  This study analyzes the early-term and long-term outcomes of carotid endarterectomy (CEA) performed in patients with low-grade (#50% on North American Symptomatic Carotid Endarterectomy Trial criteria)  ...  MRI images evocative of unstable plaque (Table III) . 7 Long-term outcomes.  ... 
doi:10.1016/j.jvs.2013.06.079 pmid:23962685 fatcat:hv54kekgezerbnhxoo4yw2lk2m

Low-cost preventive screening using carotid ultrasound in patients with diabetes

Jasjit S Suri
2020 Frontiers in Bioscience  
Preventive health check in patients with diabetes 1133 © 1996-2020 6.2. Debate on the use of CUSIP for CVD risk assessment 6.3. Measurement of Carotid Ultrasound Image-based phenotypes 6.4.  ...  A special note on clinical trials and case reports in preventive screening 8.2. Morphology-based risk assessment methods 8.3. Financial burden of diabetes mellitus in India 8.4. Manifestations 9.  ...  Table 3 . 3 Presence of stenosis in asymptomatic type 2 diabetes patients using cardiac MRI Degree of stenosis Patients without occult myocardial scar Patients with at least one oc cult m yocardial scar  ... 
doi:10.2741/4850 fatcat:36pu2zfkqrb3rgc37rvx2rpkie

Proceedings of the 33rd Annual Meeting of the Japan Academy of Neurosonology (JAN)
第33回 JAN(岩手)英文抄録集

2014 Neurosonology  
Methods: The subjects were patients with internal carotid artery stenosis who were candidates for carotid endarterectomy.  ...  Conclusions: 4D contrast-enhanced ultrasonography enabled us to evaluate the distribution of neoformed vessels in carotid plaques.  ...  Results: T1WI BB-MRI revealed high intensity plaque in 12 (40.0%) of 30 patients enrolled in the study. With CEUS imag ing, 26 (86.6%) of 30 plaque was enhanced plaque.  ... 
doi:10.2301/neurosonology.27.9 fatcat:dbv5pbbfrjeyjfwfvah5cbfvom

Lack of association of MRI determined subclinical cardiovascular disease with dizziness and vertigo in a cross-sectional population-based study

Roberto Lorbeer, Holger Hetterich, Ralf Strobl, Anina Schafnitzel, Hannah Patscheider, Andreas Schindler, Katharina Müller-Peltzer, Wieland Sommer, Annette Peters, Christa Meisinger, Margit Heier, Wolfgang Rathmann (+3 others)
2017 PLoS ONE  
Subclinical cerebrum measurements, however, tend to increase the risk for dizziness and vertigo, especially in men and in persons with prediabetes or diabetes.  ...  MRI determined subclinical cardiovascular diseases include left and right ventricular structure and function as well as the presence of carotid plaque and carotid wall thickness.  ...  Acknowledgments The contributions to data collection made by field workers, radiologists, technicians, interviewers, and computer assistants are gratefully acknowledged.  ... 
doi:10.1371/journal.pone.0184858 pmid:28910373 pmcid:PMC5599022 fatcat:djindt5ozjevha63j4xucjmr2y

The conundrum of asymptomatic carotid stenosis—determinants of decision and evidence

José Fernandes e Fernandes, Luis Mendes Pedro, Isabel Gonçalves
2020 Annals of Translational Medicine  
After review of published literature on natural history of asymptomatic carotid stenosis, diagnostic methods to identify plaque vulnerability and present-day results of both endarterectomy and stenting  ...  Stroke is a significant burden in Public Health and 11% to 15% appear as first neurologic event associated with asymptomatic carotid stenosis.  ...  This patient suffered a TIA event and high definition ultrasonography revealed sudden progression of the plaque with erosion and a mobile flap and was successfully treated by CEA.  ... 
doi:10.21037/atm-2020-cass-12 pmid:33178811 pmcid:PMC7607137 fatcat:t7fzfdbiavbfrh4gtacy7h62aa

Carotid Revascularization: An Update

Cian J. O'Kelly, Ken S. Butcher, B. Elaine Marchak, J. Max Findlay
2010 Canadian Journal of Neurological Sciences  
Symptomatic extracranial internal carotid artery stenosis poses a high short-time risk of ischemic cerebral stroke, as high as 20% to 30% in the first three months.  ...  We also provide recommendations regarding the sometime neglected but important medical management of patients undergoing carotid intervention, including antithrombotic and antihypertension therapy, lipid  ...  Younger patient age, male gender, higher degree of stenosis, evidence of brain infarction on CT or MR imaging, contralateral carotid occlusion and evidence of plaque progression are some of the proposed  ... 
doi:10.1017/s0317167100010210 fatcat:dsjprvg6s5doziihlekau5g32a

Centers for Medicare and Medicaid Services conducts a medical evidence development and coverage advisory committee meeting on carotid atherosclerosis

Richard P. Cambria
2012 Journal of Vascular Surgery  
Publication of the eagerly anticipated Carotid Revascularization Endarterectomy Versus Stenting Trial in May 2010 was anticipated to engender much activity in the realm of interventions for carotid stenosis  ...  Given that management of carotid atherosclerosis is a core element of vascular surgical practice, the SVS had a major presence at the MEDCAC in the form of a comprehensive written document individually  ...  THE High-resolution 3D ultrasound imaging with computerenhanced plaque analyses can detect plaque characteristics that may be more important than the degree of stenosis in determining stroke risk in  ... 
doi:10.1016/j.jvs.2012.04.051 pmid:22749277 fatcat:46yj6kdvzfgd7mngqijdxcjgiu

Poster Session Blue. (pp.150–180)

2009 Cerebrovascular Diseases  
The measurement of AAI among IS patients appeared to be useful to select high-risk patients and to plan adequate prevention therapies 3 Risk factors: manifestation, treatment and prognosis IS ATRIAL FIBRILLATION  ...  Conclusion: Abnormal AAI was associated with classical risk factors, especially hypertension.  ...  In those patients without carotid plaque we did not observe plaque located in the siphon. We did not observe any statistical correlation between the stenosis degree and the type pf the plaque.  ... 
doi:10.1159/000221779 fatcat:76ztyuhtevd4ljqbbgmxzvdnpi

EACVI recommendations on cardiovascular imaging for the detection of embolic sources: endorsed by the Canadian Society of Echocardiography

Ariel Cohen, Erwan Donal, Victoria Delgado, Mauro Pepi, Teresa Tsang, Bernhard Gerber, Laurie Soulat-Dufour, Gilbert Habib, Patrizio Lancellotti, Arturo Evangelista, Bibiana Cujec, Nowell Fine (+6 others)
2021 European Heart Journal-Cardiovascular Imaging  
The role of cardiac imaging—transthoracic echocardiography (TTE), transoesophageal echocardiography (TOE), cardiac computed tomography (CT), and magnetic resonance imaging (MRI)—in the diagnosis of potential  ...  We propose a diagnostic algorithm where vascular imaging and contrast TTE/TOE are considered the first-line tool in the search for a cardiac source of embolism.  ...  Acknowledgements Editorial support was provided by Sophie Rushton-Smith and Jenny Lloyd (MedLink Healthcare Communications, London) and was funded by the authors.  ... 
doi:10.1093/ehjci/jeab008 pmid:33709114 fatcat:5flhozkvmfdb5g57bf5kcnffi4

Current Treatments for Carotid Artery Disease

Kosin Thupvong, Permyos Ruengsakulrach
2011 The Bangkok Medical Journal  
The degree of carotid stenosis is associated with the degree of stroke risk.  ...  , and the risk of stroke may be lower in patients with >90% stenosis, due to post-stenotic narrowing in the distal ICA, which reduces flow and risk of embolism.  ...  cores with an overall agreement of about 75% between CTA findings and histology. 15, 16 Among the current clinically available imaging modalities, MRI seems the most accurate method to image plaque  ... 
doi:10.31524/bkkmedj.2011.02.008 fatcat:io2ktv6ddvhrnbeavdpeud4c5y

Acute small subcortical infarctions on diffusion weighted MRI: clinical presentation and aetiology

T Seifert
2005 Journal of Neurology, Neurosurgery and Psychiatry  
DWI is both sensitive and specific in the early detection of acute ischaemic brain lesions irrespective of pre-existing vascular damage.  ...  Hypertension was significantly more prevalent in the group of patients who showed a microangiopathy related imaging pattern, but this pattern did not exclude the presence of large artery disease or a possible  ...  ACKNOWLEDGEMENTS We thank P Ofner, Institute for Medical Informatics, Statistics and Documentation, Graz Medical University, and E Flooh, Department of Neurology, Graz Medical University, for skilful assistance  ... 
doi:10.1136/jnnp.2005.063594 pmid:16227543 pmcid:PMC1739418 fatcat:wzztu27khzc5rfoqf246tze4we

Therapeutic modulation of the natural history of coronary atherosclerosis: lessons learned from serial imaging studies

Jordan Andrews, Rishi Puri, Yu Kataoka, Stephen J. Nicholls, Peter J. Psaltis
2016 Cardiovascular Diagnosis and Therapy  
composition, including the presence of high-risk characteristics.  ...  into the progression of coronary plaque over time in patients with stable and unstable coronary artery disease (CAD), and its responsiveness to therapeutic interventions.  ...  More recently PET-based imaging of 18 F-sodium fluoride uptake has been used to detect high risk features of unstable plaque in patients with carotid and coronary atherosclerosis (41) .  ... 
doi:10.21037/cdt.2015.10.02 pmid:27500089 pmcid:PMC4960069 fatcat:f6h6tc7yzvd75jyf4nhnfap364

Molecular Imaging of Inflammation in Atherosclerosis

Moritz Wildgruber, Filip K. Swirski, Alma Zernecke
2013 Theranostics  
Imaging technologies used in the clinic offer minimal information about the underlying biology and potential risk for rupture.  ...  Here we will review the potential of established and new molecular imaging technologies in the setting of atherosclerosis, and discuss the cumbersome steps required for translating molecular imaging approaches  ...  MRI plaque imaging reveals high-risk carotid plaques especially in diabetic patients irrespective of the degree of stenosis. BMC medical imaging. 2010; 10: 27. doi:10.1186/1471-2342-10-27. 17.  ... 
doi:10.7150/thno.5771 pmid:24312156 pmcid:PMC3841337 fatcat:nc2cxzgrinbrxptn7oxitiqmu4
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