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MOTIF-EM: an automated computational tool for identifying conserved regions in CryoEM structures
2010
Bioinformatics
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We present a new, first-of-its-kind, fully automated computational tool MOTIF-EM for identifying regions or domains or motifs in cryoEM maps of large macromolecular assemblies (such as chaperonins, viruses ...
MOTIF-EM takes cryoEM volumetric maps as inputs. The technique used by MOTIF-EM to detect conserved sub-structures is inspired by a recent breakthrough in 2D object recognition. ...
In this article we present a new fully automated first-of-its-kind computational tool MOTIF-EM, which is meant to solve an important structural comparison problem P. ...
doi:10.1093/bioinformatics/btq195
pmid:20529921
pmcid:PMC2881380
fatcat:gitcpe66erexvojwbac7wt6jpq
Three dimensional electron microscopy and in silico tools for macromolecular structure determination
2013
EXCLI Journal : Experimental and Clinical Sciences
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A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Combining the 3DTEM data with in silico tools, one can have better refined structure of a desired complex. ...
Recently, structural biology witnessed a major tool - electron microscopy - in solving the structures of macromolecules in addition to the conventional techniques, X-ray crystallography and nuclear magnetic ...
ACKNOWLEDGEMENT Ayaluru Murali thanks University Grants Commission, New Delhi (India) for financial support. ...
pmid:27092033
pmcid:PMC4827587
fatcat:sny5lwvfnbckhpk3n2anh7dx7q
Three dimensional electron microscopy and in silico tools for macromolecular structure determination
2013
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Combining the 3DTEM data with in silico tools, one can have better refined structure of a desired complex. ...
Recently, structural biology witnessed a major tool – electron microscopy – in solving the structures of macromolecules in addition to the conventional techniques, X-ray crystallography and nuclear magnetic ...
ACKNOWLEDGEMENT Ayaluru Murali thanks University Grants Commission, New Delhi (India) for financial support. ...
doi:10.17877/de290r-10753
fatcat:3o5c25gnjnaofbffaca7f72e5m