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MB-SWIFT functional MRI during deep brain stimulation in rats

Lauri J. Lehto, Djaudat Idiyatullin, Jinjin Zhang, Lynn Utecht, Gregor Adriany, Michael Garwood, Olli Gröhn, Shalom Michaeli, Silvia Mangia
2017 NeuroImage  
) contrast in rat's brain at 9.4 T during deep brain stimulation (DBS).  ...  The results demonstrate that MB-SWIFT allows functional images free of susceptibility artifacts, and provides an excellent fMRI activation contrast in the brain.  ...  Kamil Ugurbil for stimulating discussions and comments on the manuscript.  ... 
doi:10.1016/j.neuroimage.2017.08.012 pmid:28797739 pmcid:PMC5671345 fatcat:54cym33zbzhlxehmleaei4md5u

Multi-band SWIFT enables quiet and artefact-free EEG-fMRI and awake fMRI studies in rat

Jaakko Paasonen, Hanne Laakso, Tiina Pirttimäki, Petteri Stenroos, Raimo A. Salo, Ekaterina Zhurakovskaya, Lauri J. Lehto, Heikki Tanila, Michael Garwood, Shalom Michaeli, Djaudat Idiyatullin, Silvia Mangia (+1 others)
2019 NeuroImage  
An independent component analysis of the awake rat functional connectivity data obtained with MB-SWIFT resulted in near whole-brain level functional parcellation, and simultaneous electrophysiological  ...  Functional magnetic resonance imaging (fMRI) studies in animal models provide invaluable information regarding normal and abnormal brain function, especially when combined with complementary stimulation  ...  Acknowledgements We thank Mikko Nissi, PhD, and Olli Nyk€ anen, MSc, for technical assistance in the field map experiments.  ... 
doi:10.1016/j.neuroimage.2019.116338 pmid:31730923 pmcid:PMC7008094 fatcat:tuf5yve2efdyjnkpubqrvxtc5q

Spinal cord fMRI with MB-SWIFT for assessing epidural spinal cord stimulation in rats

Hanne Laakso, Lauri J Lehto, Jaakko Paasonen, Raimo Salo, Antonietta Canna, Igor Lavrov, Shalom Michaeli, Olli Gröhn, Silvia Mangia
2021 Magnetic Resonance in Medicine  
This pilot study introduces multi-band sweep imaging with Fourier transformation (MB-SWIFT) technique for spinal cord fMRI during SCS in rats.  ...  Clear stimulation frequency-dependent responses to SCS were detected in the rat spinal cord close to the stimulation site.  ...  MB-SWIFT has been previously shown to provide betterquality fMRI data than EPI in the presence of deep brain stimulation electrodes. 31 Our results reveal an even larger difference in image quality in  ... 
doi:10.1002/mrm.28844 pmid:34002880 fatcat:pfymkw5ilrdfzgzplttvwwc2b4

Whole-brain studies of spontaneous behavior in head-fixed rats enabled by zero echo time MB-SWIFT fMRI [article]

Jaakko Paasonen, Petteri Stenroos, Hanne Laakso, Tiina Pirttimaki, Ekaterina Paasonen, Raimo A Salo, Heikki Tanila, Djaudat Idiyatullin, Michael Garwood, Shalom Michaeli, Silvia Mangia, Olli Grohn
2021 bioRxiv   pre-print
Here we demonstrate that a novel Multi-Band SWeep Imaging with Fourier Transformation (MB-SWIFT) functional magnetic resonance imaging (fMRI) approach enables whole-brain studies in spontaneously behaving  ...  Second, we show sensory, motor, exploration, and stress-related brain activity in relevant networks during corresponding spontaneous behavior.  ...  This is in good agreement with our previous work, where MB-SWIFT showed up to 3-fold higher functional signal-to-noise ratio compared to spin-echo EPI during deep brain stimulation 16 .  ... 
doi:10.1101/2021.06.15.448321 fatcat:gfwx5vstybbnjeygcbfy6hszh4

Tuning Neuromodulation Effects by Orientation Selective Deep Brain Stimulation in the Rat Medial Frontal Cortex

Lauri J. Lehto, Pavel Filip, Hanne Laakso, Alejandra Sierra, Julia P. Slopsema, Matthew D. Johnson, Lynn E. Eberly, Walter C. Low, Olli Gröhn, Heikki Tanila, Silvia Mangia, Shalom Michaeli
2018 Frontiers in Neuroscience  
Using functional MRI at 9.4 T, we monitored whole brain responses to varying the electrical field orientation of DBS within the infralimbic cortex.  ...  Previous studies that focused on treating major depressive disorder with conventional deep brain stimulation (DBS) paradigms produced inconsistent results.  ...  deep brain stimulation (DBS) therapy.  ... 
doi:10.3389/fnins.2018.00899 pmid:30618544 pmcid:PMC6300504 fatcat:6ivzrmdvojb6xbkjz7v7vvbw6e

Tracking of stem cells in vivo for cardiovascular applications

Nicole Azene, Yingli Fu, Jeremy Maurer, Dara L Kraitchman
2014 Journal of Cardiovascular Magnetic Resonance  
In the past ten years, the concept of injecting stem and progenitor cells to assist with rebuilding damaged blood vessels and myocardial tissue after injury in the heart and peripheral vasculature has  ...  In this first of a two-part review, we will review the different types of cellular labeling techniques and the application of these techniques in cardiovascular magnetic resonance and ultrasound.  ...  More recently, Garwood and coworkers have employed sweep imaging with Fourier transformation (SWIFT) for the detection of SPIOlabeled stem cells in the rat heart [145] .  ... 
doi:10.1186/1532-429x-16-7 pmid:24406054 pmcid:PMC3925252 fatcat:esubtsgb3zgkzoz5a7hwq7ujtq

Potential of MRI in Radiotherapy Mediated by Small Conjugates and Nanosystems

Putri Fauzia, Denkova, Djanashvili
2019 Inorganics  
In this review, we discuss the role of MRI in both external and internal radiotherapy focusing on the most important examples of contrast agents with combined therapeutic potential.  ...  Magnetic resonance imaging (MRI) with its superior soft-tissue resolution is already used in radiotherapy treatment planning complementing conventional computed tomography (CT).  ...  The intravenous injection of these NPs into gliosarcoma-bearing rats resulted in a swift accumulation (~10 min) in the tumor through the EPR effect.  ... 
doi:10.3390/inorganics7050059 fatcat:pjehicivbjf57hftynyhersisq

Dynamic supraparticles for the treatment of age-related diseases

Hongwei Liao, Zeyu Liang, Nan Wang, Min Wei, Ying Chen, Fangyuan Li, Daishun Ling
2019 Science Bulletin  
that allows programmed response to the spatiotemporal alterations of ARDs during progression and treatment.  ...  Recently, dynamic supraparticles (DS), which are reversibly self-assembled functional nanoparticles, have provided a novel strategy for combating ARDs.  ...  (c) In vivo T1-weighted MR images of the brain of OA-treated rats after administration of different nanocomposites or saline for 6 h (left) and corresponding color mapped images (right).  ... 
doi:10.1016/j.scib.2019.08.003 fatcat:3jvt56d7p5djxnjpsgc5dcah7m

Poster Session II

2012 Neuropsychopharmacology  
In severely ill patients, CBT is often ineffective, and treatments available for these severally ill non-responders (such as electroconvulsive therapy, vagus nerve stimulation, and deep brain stimulation  ...  Its long-term efficacy profile is similar to other ablative (eg. capsulotomy, cingulotomy) or deep brain stimulation techniques, but craniotomy is never required.  ...  In a human in vivo structural MRI study, we assessed gray matter volume of intraparietal sulcus (IPS) as a function of genotype at rs13223593 in 279 healthy Caucasian subjects.  ... 
doi:10.1038/npp.2012.220 fatcat:coblfrtlujc6hdycjbnrdwzslm

25th Congress of the European Society for Pediatric Neurosurgery (ESPN) Paris-France, 8-11 May 2016

2016 Child's Nervous System  
The age at surgery was significantly older in symptomatic patients than in Childs Nerv Syst (2016) 32:905-1012  ...  Identifying deterioration is challenging as baseline function and tethering presentations vary.  ...  This question was addressed in the rat model of neonatal hypoxia-ischemia (HI), a brain injury documented to stimulate neurogenesis.  ... 
doi:10.1007/s00381-016-3044-z pmid:27090533 fatcat:mwdou5awlbhipgxecuc3mj5qii

Abstracts from the 35th Annual Meeting of AChemS

2013 Chemical Senses  
Central glucagon-like peptide 1 receptor (GLP-1R) stimulation suppresses food intake, and hindbrain GLP-1 neurons project to numerous feeding-relevant brain regions.  ...  In rats consuming sucrose solutions, NAc core Ex9 treatment increases initial lick rate and duration of licking bursts.  ...  MRI, and 4) using SWIFT-MRI for skull imaging.  ... 
doi:10.1093/chemse/bjt036 fatcat:y46sw4p335epfkuraityepgpnm

Index [chapter]

2022 Stroke  
arteriovenous malformation, 139 in ICH-induced secondary brain injury, 92-93 during innate inflammation, 89 Microhemorrhages, cerebral, 42.  ...  disability, after stroke, 215-217 Functional electrical stimulation, for stroke recovery, 895 Functional Independence Measure (FIM), 276 inpatient rehabilitation, 879-880, 880t Fungal infections  ... 
doi:10.1016/b978-0-323-69424-7.18001-9 fatcat:i3mjz5jw65cinol2u7cmznlahq

Sympathetic neural control of integrated cardiovascular function: Insights from measurement of human sympathetic nerve activity

B. Gunnar Wallin, Nisha Charkoudian
2007 Muscle and Nerve  
Sympathetic neural control of cardiovascular function is essential for normal regulation of blood pressure and tissue perfusion.  ...  In the present review we discuss sympathetic neural mechanisms in human cardiovascular physiology and pathophysiology, with a focus on evidence from direct recordings of sympathetic nerve activity using  ...  Compound Action Potential Recordings in Rat Peripheral Nerves. Rats were anesthetized with an initial dose of 90 mg/kg IP ketamine and 10 mg/kg IP xylazine to produce deep anesthesia.  ... 
doi:10.1002/mus.20831 pmid:17623856 fatcat:ehjpmh4ztvbjfglbal2eo5qiua

Pathophysiology of Sleep Apnea

Jerome A. Dempsey, Sigrid C. Veasey, Barbara J. Morgan, Christopher P. O'Donnell
2010 Physiological Reviews  
In a recent study by Minoguchi et al. (411) , brain MRI was used to compare the percentage of silent brain infarctions in subjects with and without OSA.  ...  completely in deep NREM or slow wave sleep (15, 160) .  ... 
doi:10.1152/physrev.00043.2008 pmid:20086074 pmcid:PMC3970937 fatcat:l7ox3i7ldjdujl7bbjkwvgfx3y

10th Annual Meeting. 5th Annual Stroke Center Workshop. Society of Vascular and Interventional Neurology. November 8-11, 2017, Boston, MA: Abstracts

2017 Interventional Neurology  
MRI brain gradient-echo sequence showed laminated hemosiderin deposition inside the thrombus, postcontrast peripheral enhancement and mass effect.  ...  Parent artery occlusion with endovascular coils alone or in combination with surgical bypass has been used in the past to manage such complicated vascular lesions.  ...  and U46619induced stimulation, respectively.  ... 
doi:10.1159/000477925 fatcat:f2pcddd77ze6doe2zwccimduvy
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