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Cost analysis of emergency department

P Cremonesi, E Di Bella, M Montefiori
2010 Journal of preventive medicine and hygiene  
This paper is intended to examine both clinical and economic data concerning the activity of an emergency department of an Italian primary Hospital. Real data referring to arrivals, waiting times, service times, severity (according to triage classification) of patients' condition collected along the whole 2009 are matched up with the relevant accounting and economic information concerning the costs faced. A new methodological approach is implemented in order to identify a "standard production
more » ... st" and its variability. We believe that this kind of analysis well fits the federalizing process that Italy is experiencing. In fact the federal reform is driving our Country toward a decentralized provision and funding of local public services. The health care services are "fundamental" under the provisions of the law that in turn implies that a standard cost has to be defined for its funding. The standard cost (as it is defined by the law) relies on the concepts of appropriateness and efficiency in the production of the health care service, assuming a standard quality level as target. The identification and measurement of health care costs is therefore a crucial task propaedeutic to health services economic evaluation. Various guidelines with different amount of details have been set up for costing methods which, however, are defined in simplified frameworks and using fictious data. This study is a first attempt to proceed in the direction of a precise definition of the costs inherent to the emergency department activity.
pmid:21553561 fatcat:ghoij7ihnfcaxpkx7yeqqmbvee

MONITORING THE ACTINIDIA GERMPLASM FOR RESISTANCE TO PSEUDOMONAS SYRINGAE PV. ACTINIDIAE

P. Datson, S. Nardozza, K. Manako, J. Herrick, M. Martinez-Sanchez, C. Curtis, M. Montefiori
2015 Acta Horticulturae  
There was no definite lesion difference between R and M genotypes.  ...  differentiation criteria between R and M genotypes was hard to determine.  ... 
doi:10.17660/actahortic.2015.1095.22 fatcat:mglxj44nyfhhzobw7bwn3ybfsi

Selecting for Learning Potential: Is Implicit Learning the New Cognitive Ability?

Luke M. Montuori, Lara Montefiori
2022 Journal of Intelligence  
For decades, the field of workplace selection has been dominated by evidence that cognitive ability is the most important factor in predicting performance. Meta-analyses detailing the contributions of a wide-range of factors to workplace performance show that cognitive ability's contribution is partly mediated by the learning of task-relevant skills and job-specific declarative knowledge. Further, there is evidence to suggest that this relationship is a function of task complexity, and
more » ... mediated by learning performance in workplace induction and training activities. Simultaneously, evidence is mounting that stable individual differences in implicit learning exist, which are at least partially independent of traditional measures of intelligence. In this article we provide an overview of recent advances in our understanding of implicit learning, outline some of the advantages offered by its measurement, and highlight some of the challenges associated with its adoption as a measure of interest.
doi:10.3390/jintelligence10020024 pmid:35466237 pmcid:PMC9036310 fatcat:mqggr2xbmbcgbjxpnlqukxohue

Vaccine protection by a triple deletion mutant of simian immunodeficiency virus

M S Wyand, K H Manson, M Garcia-Moll, D Montefiori, R C Desrosiers
1996 Journal of Virology  
Supernatants were harvested at 15 days (SIVmac239⌬3) and 11 days (SIVmac316⌬nef) following transfection, clarified by low-speed centrifugation, and filtered through a 0.45-m-pore-size filter.  ...  recovery a PBMC load b Antibody Wk of challenge c 92B SIVmac316⌬nef 3 54 Ϫ d 8 H048 SIVmac316⌬nef 3 1 Ϫ 20 99S SIVmac239⌬3 2 3 Ϫ 20 8RO SIVmac239⌬3 2 1 8 Ϫ 79 3 6 91M  ... 
doi:10.1128/jvi.70.6.3724-3733.1996 fatcat:76qzbfmvubanpoqz6a64elhzym

Vaccine protection by a triple deletion mutant of simian immunodeficiency virus

M S Wyand, K H Manson, M Garcia-Moll, D Montefiori, R C Desrosiers
1996 Journal of Virology  
Supernatants were harvested at 15 days (SIVmac239⌬3) and 11 days (SIVmac316⌬nef) following transfection, clarified by low-speed centrifugation, and filtered through a 0.45-m-pore-size filter.  ...  recovery a PBMC load b Antibody Wk of challenge c 92B SIVmac316⌬nef 3 54 Ϫ d 8 H048 SIVmac316⌬nef 3 1 Ϫ 20 99S SIVmac239⌬3 2 3 Ϫ 20 8RO SIVmac239⌬3 2 1 8 Ϫ 79 3 6 91M  ... 
pmid:8648707 pmcid:PMC190248 fatcat:tvjurpazt5bvtnhoorlficppym

A promoter interaction map for cardiovascular disease genetics [article]

Lindsey E Montefiori, Debora R Sobreira, Noboru J Sakabe, Ivy Aneas, Amelia C Joslin, Grace T Hansen, Grazyna Bozek, Ivan P Moskowitz, Elizabeth M McNally, Marcelo A Nobrega
2018 bioRxiv   pre-print
Cells were strained once with a 665 100μM strainer and then once with a 40μM strainer. Cells were pelleted at 500xg and then 666 resuspended in PBS and counted.  ...  Glycine was added to a final concentration of 0.2 M to quench the reaction.  ... 
doi:10.1101/340869 fatcat:b3w4jvacgfhc5ne4vmhw3jo32y

Antiviral Antibodies Are Necessary for Control of Simian Immunodeficiency Virus Replication

C. J. Miller, M. Genesca, K. Abel, D. Montefiori, D. Forthal, K. Bost, J. Li, D. Favre, J. M. McCune
2007 Journal of Virology  
M-T477, and anti-CD8 clone no. SK1) and Becton Dickinson (San Jose, CA; anti-CD20 clone no. L27 and anti-CD79a clone no. HM47).  ...  (m to o) CD79a ϩ B cells in spleen necropsy samples. FIG. 3 . 3 Plasma vRNA levels and concentrations of CD4 ϩ T cells in blood.  ... 
doi:10.1128/jvi.02444-06 pmid:17329327 pmcid:PMC1900210 fatcat:3y66obazh5bxhca6xvhvml6v6e

Quality of Life Among Hiv Patients: Results from the Ianua Clinical Trial

M Ameri, G Cassola, G Cenderello, A Di biagio, M Giacomini, B Giannini, G Mazzarello, C Merlano, M Montefiori, P Orcamo, M Setti, C Viscoli
2015 Value in Health  
Montefiori M 1 , Orcamo P 5 , Setti M 1 , Viscoli C 3 1 University of Genoa, Genova, Italy, 2 EO Ospedali Galliera, Genoa, Italy, 3 Genoa University, Genoa, Italy, 4 Genoa University, genoa, Italy, 5  ...  PIN92 QUaLITy OF LIFE amONg HIv PaTIENTS: rESULTS FrOm THE IaNUa CLINICaL TrIaL Ameri M 1 , Cassola G 2 , Cenderello G 2 , Di biagio A 3 , Giacomini M 4 , Giannini B 4 , Mazzarello G 3 , Merlano C 5 ,  ... 
doi:10.1016/j.jval.2015.09.1525 pmid:26533328 fatcat:m64touz2qna55isyyhh4wkmarm

Synthesis and anti-HIV Activity of a Series of 2-Indolinones and Related Analogues

J. M. Smallheer, M. J. Otto, C. A. Amaral-Ly, R. A. Earl, M. J. Myers, P. Pennev, D. C. Montefiori, M. A. Wuonola
1993 Antiviral Chemistry & Chemotherapy  
M. Smallheer,'* M. J. Otto,’ C. A. Amaral-Ly,' R. A. Earl,’ M. J. Myers,’ P. Pennev,' D. C. Montefiori? and M. A. Wuonola' 'The Du Pont Merck Pharmaceutical Company, Wilmington DE 19880, USA ?  ...  Graham, B.S., Rowland, J.M., Modliszewski, A., and Montefiori, D.C. (1990) Antifusion activity in sera from persons infected with human immunodeficiency virus type 1. J. Clin Microbiol 28: 2608-2611.  ... 
doi:10.1177/095632029300400104 fatcat:wyrnnfyqx5d7xeo2hx45h43tru

Linkage of the CCR5 32 Mutation with a Functional Polymorphism of CD45RA

H.-X. Liao, D. C. Montefiori, D. D. Patel, D. M. Lee, W. K. Scott, M. Pericak-Vance, B. F. Haynes
2000 Journal of Immunology  
Acknowledgments We thank Dawn M. Jones and James R. Thomasch for expert technical assistance.  ...  Montefiori, unpublished observations). These latter two HIV-1 isolates were used after a single expansion in PBMC of original coculture supernatants.  ...  The cortex (c) and medulla (m) in A have the normal CD45RA mAb staining pattern characterized by negative staining of lymphocytes in the cortex and few positive cells in the medulla of thymus T-264.  ... 
doi:10.4049/jimmunol.165.1.148 pmid:10861047 fatcat:54k4v357pfg7pbcue3efzkjs34

Immunization by exposure to live virus (SIVmne/HIV-2287) during antiretroviral drug prophylaxis reduces risk of subsequent viral challenge [article]

Lisa M Frenkel, LaRene Kuller, Ingrid A Beck, Che-Chung Tsai, Jaimy P Joy, Thera M Mulvania, David C Montefiori, David M Anderson
2020 bioRxiv   pre-print
Azizi, A., et al., Enhancing oral vaccine potency by targeting intestinal M cells. PLoS Pathog, 2010. 6(11): p. e1001147. 65.  ...  Montefiori, D.C., et al., Neutralizing and infection-enhancing antibody 19 responses do not correlate with the differential pathogenicity of 20 SIVmac239delta3 in adult and infant rhesus monkeys.  ... 
doi:10.1101/2020.09.30.320820 fatcat:tkaqjh2kavadfecrti346nyqzy

MRI-based anatomical characterisation of lower-limb muscles in older women

Erica Montefiori, Barbara M Kalkman, William H Henson, Margaret A Paggiosi, Eugene V McCloskey, Claudia Mazzà
2020 PLoS ONE  
V M and l M were then used to calculate the muscle PCSA according to (2) : PCSA ¼ V M l o f ¼ V M k�l M ð2Þ where k is the ratio between a muscle optimal fibre length (l 0 f ) and length, as taken from  ...  Supporting information S1 https://doi.org/10.1371/journal.pone.0242973.t001 observed for V M and l M , as depicted by the bar plots in Figs 1 and 2 (individual V M and l M values are available as Supplementary  ... 
doi:10.1371/journal.pone.0242973 pmid:33259496 pmcid:PMC7707470 fatcat:7r6pgokkvned5g7gvab5wpoz6y

Eliciting neutralizing antibodies with gp120 outer domain constructs based on M-group consensus sequence

Yali Qin, Marisa Banasik, SoonJeung Kim, Adam Penn-Nicholson, Habtom H Habte, Celia LaBranche, David C Montefiori, Chong Wang, Michael W Cho
2014 Virology  
We constructed two immunogens, a monomeric gp120-OD and a trimeric gp120-OD Â 3, based on an M group consensus sequence (MCON6).  ...  A vaccine that could elicit broadly neutralizing antibodies (bnAbs) is hypothesized to be the most effective means to stop the AIDS pandemic (Haynes and Montefiori, 2006; Hoxie, 2010; Mascola and Montefiori  ...  Neutralization assays against a larger panel of pseudoviruses (in TZM-bl and A3R5 cells) were assayed in Montefiori lab as previously described McLinden et al., 2013; Montefiori, 2005) Statistical  ... 
doi:10.1016/j.virol.2014.06.006 pmid:25046154 pmcid:PMC4125429 fatcat:65naetp2f5efjhacklfrljdstu

A promoter interaction map for cardiovascular disease genetics

Lindsey E Montefiori, Debora R Sobreira, Noboru J Sakabe, Ivy Aneas, Amelia C Joslin, Grace T Hansen, Grazyna Bozek, Ivan P Moskowitz, Elizabeth M McNally, Marcelo A Nóbrega
2018 eLife  
The 3D map created by Montefiori et al. may also help to visualize how the genetic information is organized in heart cells.  ...  In addition, Montefiori et al. reveal that 90% of the non-coding regions examined were influencing genes that were far away.  ...  Additional information Author contributions Lindsey E Montefiori, Formal analysis, Methodology, Writing-original draft; Debora R Sobreira, Ivy Aneas, Amelia C Joslin, Grace T Hansen, Grazyna Bozek, Methodology  ... 
doi:10.7554/elife.35788 pmid:29988018 pmcid:PMC6053306 fatcat:4w57b6e4ubfhnpj4mwnq25ofcq

Limited ability of humoral immune responses in control of viremia during infection with SIVsmmD215 strain

T. Gaufin, R. Gautam, M. Kasheta, R. Ribeiro, E. Ribka, M. Barnes, M. Pattison, C. Tatum, J. MacFarland, D. Montefiori, A. Kaur, I. Pandrea (+1 others)
2009 Blood  
Panels G through R demonstrate the rituximab effect on intestinal CD79a ϩ B cells from both lamina propria (LP; G-L) and Peyer patches (PP; M-R).  ...  first administration of rituximab (day 28 pi) in the LNs ( Figure 2B ) and effector ( Figure 2H ) and inductive ( Figure 2N ) sites in the intestine, compared with baseline levels (Figure 2A ,G,M)  ... 
doi:10.1182/blood-2008-09-177741 pmid:19168789 pmcid:PMC2676085 fatcat:jg5rojf7anbujhvm6xnqc7b6j4
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