A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Filters
Lysosome activation in peripheral blood mononuclear cells and prognostic significance of circulating LC3B in COVID-19
2021
Briefings in Bioinformatics
Preserved Fulltext
We performed transcriptome analysis of peripheral blood mononuclear cells (PBMCs) from COVID-19 patients and identified the aberrant upregulation of genes in the lysosome pathway. ...
In conclusion, lysosome function is deregulated in PBMCs isolated from COVID-19 patients, and the related biomarker LC3B may serve as a novel tool for stratifying patients with moderate-to-severe COVID ...
Consent for publication All the authors are aware of and agree to the content of the paper, copyright assignment and authorship responsibility. ...
doi:10.1093/bib/bbab043
pmid:33620066
pmcid:PMC7929326
fatcat:bi4p76la7za6jbrdaov2eabbwi
Reduced Expression of Autophagy Markers and Expansion of Myeloid-Derived Suppressor Cells Correlate With Poor T Cell Response in Severe COVID-19 Patients
2021
Frontiers in Immunology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Here we analyzed ~140 parameters of cellular and humoral immune response in peripheral blood of 41 COVID-19 patients and 16 age/gender-matched healthy donors by flow-cytometry, quantitative PCR, western ...
Unlike increased activation of ICOS-1+ CD4+ T cells in mild COVID-19 patients (n=21), T cells in severe patients showed impaired activation, low IFN-γ production and high functional exhaustion, which correlated ...
ACKNOWLEDGMENTS The authors are grateful to Ljiljana Sofronic-Milosavljevic( INEP) and Danica C ́ujić(INEP) for generous help in serological diagnostics and critical revision of the manuscript. ...
doi:10.3389/fimmu.2021.614599
pmid:33692788
pmcid:PMC7937809
fatcat:bpmy2zbljbbyznpsdkta7vwksu
ISEV2021 Abstract Book
2021
Journal of Extracellular Vesicles
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Here, we investigate the role of X-rays, alpha, Auger and beta particles in triggering systemic effects through the activation of cGAS-STING pathway in tumor and host immune cells and assessed the role ...
GO enrichment for biological processes revealed that EXO samples were enriched in proteins related to exopeptidase activity, whereas MV samples in those related to cell redox homeostasis and intrinsic ...
Introduction: In an earlier study, we showed that under vasculogenic conditioning, pro-inflammatory cell subsets of peripheral blood mononuclear cells (PBMCs) such as macrophages type 1 (M1ɸ), T cells, ...
doi:10.1002/jev2.12083
fatcat:6m2b3nhzozac7fgsy7n2gtt2pq
16th International Congress on Neuromuscular Diseases, 21 - 22 & 28 - 29 May 2021 Virtual, Worldwide
2021
Journal of Neuromuscular Diseases
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Infection was observed in approximately 30% of the patients, and acute infl ammatory demyelinating polyneuropathy (AIDP) as the most prevalent type of GBS in 48.8%. ...
The secondary effi cacy endpoints included the changes from baseline to the end of study of adjusted INCAT disability score, grip strength in the dominant and non-dominant hand, Rasch-built overall disability ...
Results: The study has recently been completed and the data will be analyzed to evaluate the presence and relationship of TEMRA cells in circulating blood of IBM patients with disease phenotype, NT5c1A ...
doi:10.3233/jnd-219006
pmid:34334417
fatcat:5ixajewia5d3hhpkwj4yqyb32a