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Lupin Allergy: Uncovering Structural Features and Epitopes of β-conglutin Proteins in Lupinus Angustifolius L. with a Focus on Cross-allergenic Reactivity to Peanut and Other Legumes [chapter]

José C. Jimenez-Lopez, Elena Lima-Cabello, Su Melser, Rhonda C. Foley, Karam B. Singh, Alché Juan D.
2015 Lecture Notes in Computer Science  
We performed an extensive in silico analysis of seed β-conglutins, a new family of major allergen proteins in lupin, and a comparison to other relevant food allergens such as Ara h 1.  ...  cross-reactivity among lupin, peanut, and other different legumes.  ...  allergy or as a result of cross-reactivity to other legume proteins, particularly peanut, soybean, lentil, bean, chickpea, and pea [4] .  ... 
doi:10.1007/978-3-319-16483-0_10 fatcat:p2by4v26avbqhiu5fpzuibbkey

Narrow-leafed lupin (Lupinus angustifolius L.) β-conglutin proteins modulate the insulin signaling pathway as potential type 2 diabetes treatment and inflammatory-related disease amelioration

Elena Lima-Cabello, Victor Alche, Rhonda C. Foley, Sofianos Andrikopoulos, Grant Morahan, Karam B. Singh, Juan D. Alche, Jose C. Jimenez-Lopez
2017 Molecular Nutrition & Food Research  
Narrow-leafed lupin (NLL), Lupinus angustifolius (L.) seeds are rich in proteins, which belong to four main families: α, , γ, and δ conglutins [14].  ...  Scope: We have investigated the potential use of -conglutin protein isoforms from narrowleafed lupin (Lupinus angustifolius L.) as a diabetes treatment.  ...  All rights reserved. 30 allergy: uncovering structural features and epitopes of -conglutin proteins in Lupinus angustifolius L. with a focus on cross-allergenic reactivity to peanut and other legumes.  ... 
doi:10.1002/mnfr.201600819 pmid:28012244 fatcat:wfssvvcvqffzha2xgb4utjksja