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Simulating demography, genetics, and spatially explicit processes to inform reintroduction of a threatened char

Meryl C. Mims, Casey C. Day, Jacob J. Burkhart, Matthew R. Fuller, Jameson Hinkle, Andrew Bearlin, Jason B. Dunham, Patrick W. DeHaan, Zachary A. Holden, Erin E. Landguth
2019 Ecosphere  
Simulation-based approaches are a promising technique for evaluating the independent and combined effects of these factors on the outcome of various reintroduction and associated management actions.  ...  Although the importance of these factors in the success of reintroductions is well-accepted, they are typically evaluated independently, which can miss important interactions.  ...  To this end, we evaluated the role of spatial, demographic, and genetic factors in the success of reintroduction of bull trout to the lower Pend Oreille River and its tributaries.  ... 
doi:10.1002/ecs2.2589 fatcat:j4pr4lwj7ffgrmuuue63yflypm

Evolutionary advantage of directional symmetry breaking in self-replicating polymers [article]

Hemachander Subramanian, Robert A. Gatenby
2017 arXiv   pre-print
The competing requirements of low and high kinetic barriers for formation and long lifetime of inter-strand bonds respectively are simultaneously satisfied through asymmetric kinetic influence of inter-strand  ...  Here we carefully examine the physico-chemical requirements for evolutionarily successful primordial self-replicators and theoretically show that at low monomer concentrations that possibly prevailed in  ...  Acknowledgements: Support for this work was provided by the Moffitt Physical Science and Oncology Network (PS-ON) NIH grant, U 54CA193489.  ... 
arXiv:1708.02667v1 fatcat:lhdbwphxxfaoxf6z7v7i7h3s5u

Evolutionary advantage of directional symmetry breaking in self-replicating polymers

Hemachander Subramanian, Robert A. Gatenby
2018 Journal of Theoretical Biology  
for self-replication and not for de novo strand formation.  ...  The competing requirements of low and high kinetic barriers for formation and long lifetime of inter-strand bonds respectively are simultaneously satisfied through asymmetric kinetic influence of inter-strand  ...  Acknowledgments Support for this work was provided by the Moffitt Physical Science and Oncology Network (PS-ON) NIH grant, U54CA193489.  ... 
doi:10.1016/j.jtbi.2018.03.012 pmid:29544886 pmcid:PMC5891365 fatcat:3ntin2gsyvayniaup6wucpvwzi


B. C. Harvey, S. F. Railsback
2011 Rivers Research and Applications: an international journal devoted to river research and management  
For stream fish, barriers to upstream passage, such as waterfalls or culverts with perched outlets, are a common cause of fragmentation.  ...  The influence of variation in the value of parameter fishEMForUnknownCells on (left) mean number of segments occupied and (right) overall abundance, under upstream-passage barrier scenarios 2 and 5.  ...  In all 10 replicates for the stream network lacking barriers, fish occupied the entire network throughout the simulation period.  ... 
doi:10.1002/rra.1574 fatcat:qix3n6nkobakjjzqkrwcpbzrb4

Page 338 of Journal of Science Education and Technology Vol. 14, Issue 3 [page]

2005 Journal of Science Education and Technology  
338 underrepresentation of minority students at the high- est levels represents a barrier to successful integra- tion of society in the United States.  ...  Results of these evaluations are, how- ever, positive and suggest that workshop approaches have real promise for improving the performance and retention of minority students in science and engineering  ... 

Challenges of sperm cryopreservation in transferring heat adaptation of corals across ocean basins

Emily J. Howells, Mary Hagedorn, Madeleine J.H. Van Oppen, John A. Burt
2022 PeerJ  
Average fertilization success for the Persian Gulf (9%) and Oman Sea (6%) sperm were 1.4–2.5 times lower than those for the native cryopreserved sperm from Great Barrier Reef (13–15%), potentially due  ...  To evaluate whether cross-bred offspring had enhanced thermal tolerance, the survival of larvae sired by Persian Gulf cryopreserved sperm, Great Barrier Reef cryopreserved sperm, and Great Barrier Reef  ...  ACKNOWLEDGEMENTS We thank D Abrego, G Vaughan, A Severati for assistance with coral collections; and VL Carter for assistance with the cryopreservation of Great Barrier Reef coral sperm.  ... 
doi:10.7717/peerj.13395 pmid:35651741 pmcid:PMC9150692 fatcat:3u52zwwnznhbbhw5v3y5tsci7y

Drug transport across the human placenta: review of placenta-on-a-chip and previous approaches

Rajeendra L. Pemathilaka, David E. Reynolds, Nicole N. Hashemi
2019 Interface Focus  
The creation of an in vitro microengineered model of the placenta can be used to replicate the interactions between the mother and fetus, specifically pharmaceutical drug intake reactions.  ...  This review is based on past and current research that compares the feasibility and testing of the placenta-on-a-chip microengineered model to the previous and underdeveloped in vivo and ex vivo approaches  ...  to analyse, visualize, and replicate the human placental structure in vitro the microchip's success has opened the doors for evaluating pathogens, chemicals and drug transfer across the human placental  ... 
doi:10.1098/rsfs.2019.0031 pmid:31485316 pmcid:PMC6710654 fatcat:pelqoem5yvgspdem63plylwz44

Physical Characterisation of an Alginate/Lysozyme Nano-Laminate Coating and Its Evaluation on 'Coalho' Cheese Shelf Life

Bartolomeu G. de S. Medeiros, Marthyna P. Souza, Ana C. Pinheiro, Ana I. Bourbon, Miguel A. Cerqueira, António A. Vicente, Maria G. Carneiro-da-Cunha
2013 Food and Bioprocess Technology  
UV/VIS spectroscopy and contact angle analyses confirmed the layers' deposition and the successful assembly of nano-laminate coating on A/C PET surface.  ...  This work aimed at the characterisation of a nanolaminate coating produced by the layer-by-layer methodology and its evaluation on the preservation of 'Coalho' cheese.  ...  The absorbance of successive deposition of layers was measured at 266 nm, after the deposition of each layer (and upon drying). Three replications of the measurements were taken.  ... 
doi:10.1007/s11947-013-1097-5 fatcat:6wxrtekcdrgbxcn2feqnj5dxrm

Evolutionary advantage of a broken symmetry in autocatalytic polymers explains fundamental properties of DNA [article]

Hemachander Subramanian, Robert A. Gatenby
2017 arXiv   pre-print
in the Darwinian competition for space and common substrates.  ...  Here we utilize a very simple model of hypothetical self-replicating polymers to show that asymmetric autocatalytic polymers are more successful in self-replication compared to their symmetric counterparts  ...  Acknowledgements: Support for this work was provided by the Moffitt Physical Science and Oncology Network (PS-ON) NIH grant, U 54CA193489.  ... 
arXiv:1605.00748v3 fatcat:6yg24d34dfestp72mgs2fdlovm

Emerging therapies in pipeline for chronic hepatitis C

Navjot Kaur, Harish Negi, Avaneesh Pandey
2013 International Journal of Basic & Clinical Pharmacology  
Current review aims to discuss the emerging therapies in pipeline for chronic hepatitis C outlining their mode of action and current stage of development in clinical trials.  ...  The current standard therapy is limited both in efficacy and tolerability which highlights the large unmet medical need in this area.  ...  OF CURRENT THERAPIES A major barrier to successful treatment with current pegylated interferon and ribavirin therapy is the frequent occurrence of adverse events.  ... 
doi:10.5455/2319-2003.ijbcp20131001 fatcat:r4zii4flq5aerbqqdmtsxiubsy

Perspectives and challenges of interferon-free therapy for chronic hepatitis C

Christian M. Lange, Stefan Zeuzem
2013 Journal of Hepatology  
Despite the successful implementation of telaprevir-and boceprevir-based triple therapies, all-oral regimens will certainly become a first choice for a number of HCV-infected patients in the very near  ...  In this review, we summarize available data of interferon-free regimens for the treatment of chronic hepatitis C and assess implications for perspectives and challenges in the further development of all-oral  ...  Because NNIs bind distantly to the active centre of NS5B, their barrier to resistance is significantly lower as for NIs, and viral breakthrough has frequently been observed in monotherapy studies evaluating  ... 
doi:10.1016/j.jhep.2012.10.019 pmid:23104162 fatcat:lrm3kyxy7fe7tj55xmxyopffzy

Conspecific sperm precedence is reinforced, but postcopulatory sexual selection weakened, in sympatric populations of Drosophila

Dean M. Castillo, Leonie C. Moyle
2019 Proceedings of the Royal Society of London. Biological Sciences  
This might be particularly important in the context of 'reinforcement', where selection acts directly to increase prezygotic barriers to reduce the cost of heterospecific matings.  ...  We also find these D. pseudoobscura populations have decreased sperm competitive ability against conspecifics, reducing the opportunity for sexual selection within these populations.  ...  Walburn and J. Roesener for assistance with crosses and scoring progeny, J. Powers and the IU Light Microscopy Imaging Center for assistance with the Leica microscope, M. Noor, A. Hish, and N.  ... 
doi:10.1098/rspb.2018.2535 pmid:30900533 pmcid:PMC6452082 fatcat:blengrtqnzgdnpdqu3omck5hpu

Countering Disruptive Innovations

Boniface Okanga
2022 International Journal of Innovation and Economic Development  
Countering disruptive innovations is critical for bolstering a business' continuity and sustainability.  ...  a business model that the executives can replicate to counter disruptive innovations.  ...  of Johannesburg for offering the intellectual support that rendered the successful accomplishment of this research.  ... 
doi:10.18775/ijied.1849-7551-7020.2015.76.2004 fatcat:hhe5lxm66vhkfgbqgud7aold5m

Comparison of Endemic and Epidemic Vesicular Stomatitis Virus Lineages in Culicoides sonorensis Midges

Paula Rozo-Lopez, Steven J. Pauszek, Lauro Velazquez-Salinas, Luis L. Rodriguez, Yoonseong Park, Barbara S. Drolet
2022 Viruses  
in the U.S., nor the genetic basis for such incursions.  ...  Here, we compared the efficiency of these two viral lineages to infect the vector Culicoides sonorensis (Wirth and Jones) and disseminate to salivary glands for subsequent transmission.  ...  Swanson, and W. Yarnell, at the Arthropod-Borne Animal Diseases Research Unit, USDA, ARS, Manhattan, KS, for their technical assistance.  ... 
doi:10.3390/v14061221 pmid:35746691 pmcid:PMC9230599 fatcat:hydzu3q5cjcu3iawc6jrjwpckm

Evaluation of Prezygotic Barrier Using Laboratory Crosses Between Three Species of Blue Mussels of The Genus Mytilus, Present Along the Chilean Coast

Jorge E Toro
2021 Biomedical Journal of Scientific & Technical Research  
More studies are needed to establish the fitness of larvae and juveniles obtained by each of these crosses, because, even if there is no reproductive barrier between species the viability and survivorship  ...  Therefore, no prezygotic barrier was found in any of the interspecies crosses.  ...  Therefore, to understand the ecological and evolutionary processes that promote the invasion is of fundamental importance to elucidate the fecundity success and/or the presence of prezygotic barriers between  ... 
doi:10.26717/bjstr.2021.34.005505 fatcat:emre42uk3nbzth2fu6cyipjcj4
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