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Neuroanatomical Correlates in Bilinguals: The Case of Children and Elderly [article]

Lorna García-Pentón, Yuriem Fernández, Jon Andoni Duñabeitia, Alejandro Pérez, Manuel Carreiras
2019 bioRxiv   pre-print
holder for this preprint . doi: bioRxiv preprint first posted online Mar. 25, 2019; White matter connectivity For details in the connectivity analysis procedure see Garcia-Penton  ... 
doi:10.1101/586768 fatcat:e6udfjedsbhnxnt5esffgj6cuu

Neglectful maternal caregiving involves altered brain plasticity in empathy-related areas [article]

Maria Jose Rodrigo, Inmaculada Leon, Lorna Garcia-Penton, Juan Andres Hernandez-Cabrera, Ileana Quinones
2019 bioRxiv   pre-print
The maternal brain undergoes functional and structural adaptations to sensitive caregiving that are critical for ensuring infant wellbeing. This study investigates brain structural alterations in neglectful caregiving and their impact on mother-child interactive behavior. High-resolution 3D volumetric images were obtained on 25 neglectful (NM) and 23 non-neglectful control (CM) mothers. Using Voxel-Based Morphometry, we compared gray and white matter volume (GMV/WMV) between the two groups.
more » ... ers also completed an empathy scale and participated with their children in a standardized play task (Emotional Availability Scale, EA). NM, as compared to CM, showed GMV reductions in right insula, anterior/middle cingulate, and right inferior frontal gyrus (IFG), as well as WMV reductions in bilateral frontal regions. A GMV increase was observed in the right fusiform and cerebellum. Regression analyses showed a negative effect of fusiform GMV and a positive effect of right frontal WMV on EA Mediation analyses showed the mediating role of emotional empathy in the positive effect of insula and IFG, and the negative effect of cerebellum on EA. Neglectful mothering involves an altered plasticity in emotional empathy-related areas and in frontal areas associated with poor mother-child interactive bonding, indicating how critical the structural changes in these areas are for infant wellbeing.
doi:10.1101/654434 fatcat:lcdgo47fbreing7vrgdqslt3na

Cortical surface alterations in cingulate and frontal regulatory areas underlies insensitive mothering [article]

Inmaculada Leon, Maria Jose Rodrigo, Ileana Quinones, Juan Andres Hernandez-Cabrera, Lorna Garcia-Penton
2020 bioRxiv   pre-print
This study focuses on severe insensitive or neglectful mothering, the most prevalent type of child maltreatment, to examine cortical surface feature alterations underlying maternal functioning and their impact on mother-child interactive bonding. High-resolution 3D volumetric images were obtained on 24 neglectful (NM) and 21 non-neglectful control (CM) mothers. Using surface-based morphometry, we compared differences in cortical thickness and surface area. Mothers completed alexithymia and
more » ... cal integrity measures and participated with their children in a play task (Emotional Availability Scale). We found cortical thinning for NM in the right rostral middle frontal gyrus and the right anterior/medial cingulate cortex, and also increased surface area in the right occipital lingual and fusiform areas and the caudal middle frontal area. Mediation analyses showed that cognitive integrity and alexithymia mediated, respectively, the positive and negative effect of the rostral middle frontal gyrus on Emotional Availability. The findings suggest cortical thinning in the rostral frontal area underlying high-order regulatory functioning as being critical for poor maternal self-awareness of emotions and the organization of coordinated actions during mother-child interactive bonding.
doi:10.1101/2020.01.29.924613 fatcat:nq7bltbndbbyhn2kgmo3sz7bpe

Distinctive Frontal and Occipitotemporal Surface Features in Neglectful Parenting

Inmaculada León, María José Rodrigo, Ileana Quiñones, Juan Andrés Hernández-Cabrera, Lorna García-Pentón
2021 Brain Sciences  
Data availability: The structural MRI data and the covariates scores that support the findings of this study are available in a GIN repository:  ... 
doi:10.3390/brainsci11030387 pmid:33803895 fatcat:voap4galufarbaby7ezlah6s7y

Complex brain network properties in late L2 learners and native speakers

Alejandro Pérez, Margaret Gillon Dowens, Nicola Molinaro, Yasser Iturria-Medina, Paulo Barraza, Lorna García-Pentón, Manuel Carreiras
2015 Neuropsychologia  
Whether the neural mechanisms that underlie the processing of a second language in highly proficient late bilinguals (L2 late learners) are similar or not to those that underlie the processing of the first language (L1) is still an issue under debate. In this study, a group of late learners of Spanish whose native language is English and a group of Spanish monolinguals were compared while they read sentences, some of which contained syntactic violations. A brain complex network analysis
more » ... was used to assess the time-varying topological properties of the functional networks extracted from the electroencephalography (EEG) recording. Late L2 learners showed a lower degree of parallel information transfer and a slower propagation between regions of the brain functional networks while processing sentences containing a gender mismatch condition as compared with a standard sentence configuration. In contrast, no such differences between these conditions were detected in the Spanish monolinguals. This indicates that when a morphosyntactic language incongruence that does not exist in the native language is presented in the second language, the neural activation pattern is configured differently in highly proficient late bilinguals than in monolinguals.
doi:10.1016/j.neuropsychologia.2015.01.021 pmid:25598315 fatcat:2jaalvaocnebvaq5kfras2wodm

Anatomical and functional changes in the brain after simultaneous interpreting training: A longitudinal study

Eowyn Van de Putte, Wouter De Baene, Lorna García-Pentón, Evy Woumans, Aster Dijkgraaf, Wouter Duyck
2018 Cortex  
Structural Connectivity analysis For this analysis, we followed the same procedure used by García-Pentón et al. (2014) .  ...  Bai et al., 2012; García-Pentón et al., 2014; Verstraete et al., 2011; Zalesky et al., 2010b) . RESULTS Behavioral data The behavioral data was analyzed with SPSS 24 (Table 3) .  ... 
doi:10.1016/j.cortex.2017.11.024 pmid:29291529 fatcat:kn7rdcofc5dzvhml7zjfxbq4pe

Brain Hemispheric Structural Efficiency and Interconnectivity Rightward Asymmetry in Human and Nonhuman Primates

Yasser Iturria-Medina, Alejandro Pérez Fernández, David M. Morris, Erick J. Canales-Rodríguez, Hamied A. Haroon, Lorna García Pentón, Mark Augath, Lídice Galán García, Nikos Logothetis, Geoffrey J. M. Parker, Lester Melie-García
2010 Cerebral Cortex  
Evidence for interregional structural asymmetries has been previously reported for brain anatomic regions supporting welldescribed functional lateralization. Here, we aimed to investigate whether the two brain hemispheres demonstrate dissimilar general structural attributes implying different principles on information flow management. Common left hemisphere/right hemisphere structural network properties are estimated and compared for right-handed healthy human subjects and a nonhuman primate,
more » ... means of 3 different diffusion-weighted magnetic resonance imaging fiber tractography algorithms and a graph theory framework. In both the human and the nonhuman primate, the data support the conclusion that, in terms of the graph framework, the right hemisphere is significantly more efficient and interconnected than the left hemisphere, whereas the left hemisphere presents more central or indispensable regions for the whole-brain structural network than the right hemisphere. From our point of view, in terms of functional principles, this pattern could be related with the fact that the left hemisphere has a leading role for highly demanding specific process, such as language and motor actions, which may require dedicated specialized networks, whereas the right hemisphere has a leading role for more general process, such as integration tasks, which may require a more general level of interconnection.
doi:10.1093/cercor/bhq058 pmid:20382642 fatcat:dtph4ocb5bhhjihg4vw2wljbge

Automated Discrimination of Brain Pathological State Attending to Complex Structural Brain Network Properties: The Shiverer Mutant Mouse Case

Yasser Iturria-Medina, Alejandro Pérez Fernández, Pedro Valdés Hernández, Lorna García Pentón, Erick J. Canales-Rodríguez, Lester Melie-Garcia, Agustin Lage Castellanos, Marlis Ontivero Ortega, Yong He
2011 PLoS ONE  
Neuroimaging classification procedures between normal and pathological subjects are sparse and highly dependent of an expert's clinical criterion. Here, we aimed to investigate whether possible brain structural network differences in the shiverer mouse mutant, a relevant animal model of myelin related diseases, can reflect intrinsic individual brain properties that allow the automatic discrimination between the shiverer and normal subjects. Common structural networks properties between shiverer
more » ... (C3Fe.SWV Mbp shi /Mbp shi , n = 6) and background control (C3HeB.FeJ, n = 6) mice are estimated and compared by means of three diffusion weighted MRI (DW-MRI) fiber tractography algorithms and a graph framework. Firstly, we found that brain networks of control group are significantly more clustered, modularized, efficient and optimized than those of the shiverer group, which presented significantly increased characteristic path length. These results are in line with previous structural/functional complex brain networks analysis that have revealed topologic differences and brain network randomization associated to specific states of human brain pathology. In addition, by means of network measures spatial representations and discrimination analysis, we show that it is possible to classify with high accuracy to which group each subject belongs, providing also a probability value of being a normal or shiverer subject as an individual anatomical classifier. The obtained correct predictions (e.g., around 91.6-100%) and clear spatial subdivisions between control and shiverer mice, suggest that there might exist specific network subspaces corresponding to specific brain disorders, supporting also the point of view that complex brain network analyses constitutes promising tools in the future creation of interpretable imaging biomarkers.
doi:10.1371/journal.pone.0019071 pmid:21637753 pmcid:PMC3103505 fatcat:omhlyxem6jg4dp3wv5bx6lj7fa

Diferencias, discriminación, cerebro y sexo: controversias científicas de lo social y lo biológico

Saray Ayala, Simone Belli, Fernando Broncano
2015 Encrucijadas: Revista Crítica de Ciencias Sociales  
Según el estudio de Lorna García-Pentón y colaboradores, las personas que son bilingües desde una edad temprana desarrollan estructuras dentro del cerebro mucho mejor interconectadas que aquellas personas  ...  Un artículo que se acaba de publicar en la no menos prestigiosa revista científica NeuroImage demuestra justamente eso (García-Pentón et al., 2014) .  ... 
doaj:f16205c06cdb48c29afbd07f08fc4b36 fatcat:vfvnruwzdrf5dewnqgwur5bvnq

Limbic-visual attenuation to crying faces underlies neglectful mothering

Inmaculada León, María José Rodrigo, Wael El-Deredy, Cristián Modroño, Juan Andrés Hernández-Cabrera, Ileana Quiñones
2019 Scientific Reports  
Acknowledgements Special thanks for their helpful advice to Manuel de Vega, Steren Chabert, Alejandro Weinstein and Lorna García-Pentón; and for his assistance in graphic design to Liudmila Chirolde.  ... 
doi:10.1038/s41598-019-42908-1 pmid:31011201 pmcid:PMC6476884 fatcat:vnx4fvvnlvba7mjkyxdzqehoju

Impacte del bilingüisme sobre l'estructura cerebral

Ferran Suay, Lerma, Anthyma Soler
2015 unpublished
Impacte del bilinbüisme sobre l'estructura cerebral Ferran Suay i Anthyma Franco (2015) GARCÍA-PENTÓN, LORNA; PÉREZ FERNÁNDEZ, ALEJANDRO; ITURRIAMEDINA, YASSER; GILLON-DOWENS, MARGARET; CARREIRAS, MANUEL  ...  En BL primerencs també s'ha observat una connectivitat superior en àrees temporoparietals i frontals esquerres (García-Pentón et al. 2014) .  ... 

Supplemental Material for Proceedings of the American Psychological Association for the Legislative Year 2014 : Minutes of the Annual Meeting of the Council of Representatives, February 21–23, 2014, Washington, DC, and August 6 and August 8, 2014, Washington, DC, and Minutes of the February, June, August, and December 2014 Meetings of the Board of Directors

2015 American Psychologist  
Fietzer, Alexander William Figueroa-Garcia, Alberto Fink, Cristina Ann Fink, Julie A. Fink, Victoria Finlay, Andrea Finlay, Lisa D.  ...  Henrichs, Bethany Ann Henry, Noelle Hernandez, Brenda Hernandez, Michelle Adriana Heskett, Desiree Rochelle Hewitt-Gill, Crystal Hicks, Lorna D. Hill, Everette W.  ... 
doi:10.1037/a0039369.supp fatcat:uawfjspuybevrgatrvaitctbde

List of Members of the Modern Language Association of America

1950 Publications of the Modern Language Association of America  
. —6) 26 Garcia, Barbara M., Asst. Prof. Soanish, Mills C, Oakland 13, Calif. 50 Garcia-Lorca, Isabel, Dept. Span., Sarah Lawrence C, Bronxville 8 N. Y. [316 N. 94 St., N Y. C. 25) 49 Gardiner, Mrs.  ...  Eng., Provi- dence R, Providence 8, i 4° McGuffie, Helen penton, Asst. Prof. Eng Bethany C, m— me W. Va. [Box 81] “Gi —. John F., St. Ambrose C, eer 4 a. oMctiale, Carlos F., Asst. Prof.  ... 
doi:10.1632/s003081290017957x fatcat:muk7nrey7nfzxoguawozamkmwi