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Short-term effect of changes in smoking behaviour on emphysema quantification by CT
2010
Thorax
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The effect of smoking cessation and smoking relapse on lung density was studied using low-dose CT. ...
Methods Spiral, multidetector, low-dose CT was performed on 726 current and former smokers (>20 pack-years) recruited from a cancer screening trial. ...
Funding The Danish Lung Cancer Screening Trial receives financial support from the Danish Ministry of Interior and Health. ...
doi:10.1136/thx.2009.132688
pmid:20978026
fatcat:ntntpzmsczhgjf264kd5blqjdm
Progress in Imaging COPD, 2004 - 2014
2014
Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation
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for lung cancer screening. ...
Quantitative CT permits evaluation of severity of emphysema, airway wall thickening, and expiratory air trapping, and is now being used for longitudinal evaluation of the progression of COPD. ...
Longitudinal Evaluation Several studies have evaluated the ability of CT to detect progression of emphysema on longitudinal evaluation ( Figure 7 ). ...
doi:10.15326/jcopdf.1.1.2014.0125
pmid:28848813
pmcid:PMC5559143
fatcat:3vkwvlh5cje4bdjtejkmowzoyq
Association of the transfer coefficient of the lung for carbon monoxide with emphysema progression in male smokers
2011
European Respiratory Journal
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Heavy smokers, mean¡SD 41.3¡18.7 pack-yrs, participating in a lung cancer screening trial underwent diffusion testing and CT scanning of the lungs. ...
We evaluated whether in heavy smokers, baseline KCO was associated with the progression of computed tomography (CT)-detected emphysema, and the progression of airflow limitation. ...
Heavy smokers, mean¡SD 41.3¡18.7 pack-yrs, participating in a lung cancer screening trial underwent diffusion testing and CT scanning of the lungs. ...
doi:10.1183/09031936.00050711
pmid:21565924
fatcat:g3a4yaqyjvc6xkvvo7526izobm
Prospective CT Screening for Lung Cancer in a High-Risk Population: HIV-Positive Smokers
2014
Journal of Thoracic Oncology
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The heterogeneity of emphysema across the entire lung as measured by CT densitometry was significantly higher in HIV-infected subjects with lung cancer compared with the heterogeneity of emphysema in those ...
On multivariate regression analysis, increased age, higher smoking pack-years, low CD4 nadir, and increased heterogeneity of emphysema on quantitative CT imaging were all significantly associated with ...
Participants were to have a low-dose helical CT scan at baseline (T0) and up to four scans annually (T1-T4). ...
doi:10.1097/jto.0000000000000161
pmid:24828660
pmcid:PMC4023914
fatcat:hukn7j2b5bhrzcfrouvalmnvua
CT Scan Screening for Lung Cancer: Risk Factors for Nodules and Malignancy in a High-Risk Urban Cohort
2012
PLoS ONE
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Low-dose computed tomography (CT) for lung cancer screening can reduce lung cancer mortality. The National Lung Screening Trial reported a 20% reduction in lung cancer mortality in high-risk smokers. ...
Methods: We performed a longitudinal lung cancer biomarker discovery trial (NYU LCBC) that included low-dose CTscreening of high-risk individuals over 50 years of age, with more than 20 pack-year smoking ...
In contrast, as mentioned, the NLST found that screening with low-dose chest CTs can identify early lung cancers and decrease lung cancer mortality, but at the cost of large numbers of non-specific NCN ...
doi:10.1371/journal.pone.0039403
pmid:22768300
pmcid:PMC3388074
fatcat:egq4e6jwwfaa5nxwyxvxd4okci
CT-quantified emphysema in male heavy smokers: association with lung function decline
2011
Thorax
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Methods Current and former heavy smokers participating in a lung cancer screening trial were recruited to the study and all underwent CT. Spirometry was performed at baseline and at 3-year follow-up. ...
Conclusion Greater baseline severity of CT-detected emphysema is related to lower baseline lung function and greater rates of lung function decline, even in those without airway obstruction. ...
of emphysema are frequently found on CT scans performed in lung cancer screening trials studying heavy smokers who are also at a great risk of developing COPD, but this CT-detected emphysema is often ...
doi:10.1136/thx.2010.145995
pmid:21474499
fatcat:6ppjdymfpne7njfeaiox3eac6m
Maintaining lung health with longstanding HIV
2016
Current Opinion in Infectious Diseases
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Recent Findings-Diagnoses of COPD are now up to 50% more prevalent in HIV-seropositive individuals than HIV-uninfected controls, and prospective pulmonary function studies find significant impairment in ...
Although host factors such as age and smoking have a role, HIV is an independent contributor to the pathogenesis of COPD, PAH and lung cancer. ...
Initial reports from the French HIV CHEST study, targeting HIV-seropositive individuals over 40 years of age with significant recent smoking history, suggest that using low dose CT thorax for early lung ...
doi:10.1097/qco.0000000000000221
pmid:26555039
pmcid:PMC4689652
fatcat:jv5hwgplvzcxldizcwvolstbuq
Association of incidental emphysema with annual lung function decline and future development of airflow limitation
2016
International Journal of COPD
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of emphysema scoring calculated from our low radiation dose CT protocol without modification, which is fitted for lung cancer screening ...
mortality in cases with %LAA −950 .10%. 5,6 Since minimal differences were reported in the quantification of emphysema between standard radiation dose and low radiation dose CT techniques, we used values ...
Disclosure The authors report no conflicts of interest in this work. ...
doi:10.2147/copd.s96809
pmid:26893550
pmcid:PMC4745855
fatcat:hzefzqskqjehnd3tmvonvotfw4
Early detection of COPD is important for lung cancer surveillance
2011
European Respiratory Journal
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Low-dose computed tomography (LDCT) is an effective procedure for the early detection of lung cancer in high-risk patients. ...
We propose that, for the prevention of both diseases, COPD screening in smokers should be initiated as early as possible, so they can stop smoking and so that candidates for an efficient lung cancer screening ...
From a 20-yr follow-up study of 448,600 lifelong nonsmokers, TURNER et al. ...
doi:10.1183/09031936.00126011
pmid:22088970
fatcat:ifp4vpkytja63b2av4z3pdlns4
ESR/ERS white paper on lung cancer screening
2015
European Radiology
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Annual low-dose computed tomography has shown a survival benefit in screening individuals at high risk for lung cancer. ...
Key points • Lung cancer screening using low dose computed tomography reduces mortality. • Leading US medical societies recommend large scale screening for high-risk individuals. • There are no lung cancer ...
Acknowledgments We acknowledge the support from the ESR office, in particular Chiara Manavella. ...
doi:10.1007/s00330-015-3697-0
pmid:25929939
pmcid:PMC4529446
fatcat:23arpid6wvbsvjavneioo5uh3m
ESR/ERS white paper on lung cancer screening
2015
European Respiratory Journal
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Annual low-dose computed tomography has shown a survival benefit in screening individuals at high risk for lung cancer. ...
Key points • Lung cancer screening using low dose computed tomography reduces mortality. • Leading US medical societies recommend large scale screening for high-risk individuals. • There are no lung cancer ...
Acknowledgments We acknowledge the support from the ESR office, in particular Chiara Manavella. ...
doi:10.1183/09031936.00033015
pmid:25929956
pmcid:PMC4486375
fatcat:urpejc7hfjertismmqgbftkzea
New developments in the assessment of COPD: early diagnosis is key
2014
International Journal of COPD
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However, there is strong evidence to suggest that the majority of patients with objective COPD are not aware of their condition, and this leads to a significant delay in diagnosis, more aggressive smoking-cessation ...
a rapid decline in lung function occurs and may be prevented if acted upon. ...
emphysema, air trapping, and bronchial wall thickening to pre-bronchodilator spirometry in 1,140 male lung-cancer screening participants using low-dose CT with inspiratory and expiratory sequences. ...
doi:10.2147/copd.s46198
pmid:24600220
pmcid:PMC3942111
fatcat:nvb3inr23zddrpxkmho5jpqtry
Lung Cancer Screening: Evidence, Risks, and Opportunities for Implementation
Lungenkrebs-Screening: Evidenz, Risiken und Möglichkeiten der Implementierung
2021
RöFo. Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren (Print)
Lungenkrebs-Screening: Evidenz, Risiken und Möglichkeiten der Implementierung
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Several trials with different screening approaches have recognized the role of lung cancer screening with low-dose CT for reducing lung cancer mortality. ...
The efficacy of lung cancer screening depends on many factors and implementation is still pending in most European countries. ...
low-dose CT. ...
doi:10.1055/a-1382-8648
pmid:33772489
fatcat:wikizkfohrfxxootmzpmwauzau
Chemotherapy for advanced lung cancer: is the glass half full or half empty?
2004
Thorax
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to follow the progression of emphysema in vivo. ...
Cohort studies can be divided into cross sectional studies and follow up studies. ...
doi:10.1136/thx.2004.025916
pmid:15454643
pmcid:PMC1746839
fatcat:nflyno5xrjclnefkfhzfzeo4fu
Pi MZ and COPD: will we ever know?
2004
Thorax
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to follow the progression of emphysema in vivo. ...
Cohort studies can be divided into cross sectional studies and follow up studies. ...
doi:10.1136/thx.2004.024810
pmid:15454645
pmcid:PMC1746850
fatcat:f367qap7c5a65pnn2e375iz3lm
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