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Correlation of in vivo and ex vivo1H-MRI with histology in two severities of mouse spinal cord injury

Harun N. Noristani, Nicolas Lonjon, Maïda Cardoso, Marine Le Corre, Emilie Chan-Seng, Guillaume Captier, Alain Privat, Christophe Coillot, Christophe Goze-Bac, Florence E. Perrin
2015 Frontiers in Neuroanatomy  
Magnetic resonance imaging (MRI) technology is the only method used to assess the impact of an injury on the structure and function of the human spinal cord.  ...  Due to the remarkable potential of transgenic mice for studying the pathophysiology of SCI, we examined the use of both in and ex vivo 1 H-MRI (9.4 T) in two severities of the mouse SCI (hemisection and  ...  Acknowledgments This study was supported by "Verticale" to HN and FP and by "Demain Debout Aquitaine" to MC, two spinal cord injured patient organizations.  ... 
doi:10.3389/fnana.2015.00024 pmid:25798092 pmcid:PMC4350395 fatcat:fjevtgjy4nhftlveyqrn7cmhsa

Diffusion Tensor Imaging-Based Studies at the Group-Level Applied to Animal Models of Neurodegenerative Diseases

Hans-Peter Müller, Francesco Roselli, Volker Rasche, Jan Kassubek
2020 Frontiers in Neuroscience  
of diffusion tensor imaging (DTI).  ...  The translational aspect from in-vivo animal models toward (clinical) applications in humans is covered as well as the DTI-based research of the non-human brains' microstructure, the methodological aspects  ...  ACKNOWLEDGMENTS We would like to thank the Ulm University Center for Translational Imaging MoMAN for its support.  ... 
doi:10.3389/fnins.2020.00734 pmid:32982659 pmcid:PMC7487414 fatcat:fwb2izfuybfarfdkp4bqqfspum

Test-retest reproducibility of in vivo magnetization transfer ratio and saturation index in mice at 9.4 Tesla [article]

Naila Rahman, Jordan Ramnarine, Kathy Xu, Arthur Brown, Corey A Baron
2021 bioRxiv   pre-print
Purpose: To assess the test-retest reproducibility of MTR and MTsat in the mouse brain at 9.4 T and calculate sample sizes required to detect various effect sizes. Study Type: Prospective.  ...  Animal Model: C57Bl/6 Mouse Model (6 females and 6 males, aged 12 to 14 weeks). Field Strength/Sequence: Magnetization Transfer Imaging at 9.4 T.  ...  Longitudinal assessment of recovery after spinal cord injury with behavioral measures and diffusion, quantitative magnetization transfer and functional magnetic resonance imaging.  ... 
doi:10.1101/2021.12.10.472129 fatcat:u5gebsk7mng3bbkq4akesl3aay

ACTRIMS-ECTRIMS MSBoston 2014: Poster Sessions 2

2014 Multiple Sclerosis  
P507 The nature of white matter tract injury in relapsingremitting multiple sclerosis: a diffusion-tensor imaging study in relation to disease duration A Background: Diffusion-tensor imaging (DTI) studies  ...  P495 High field spinal cord imaging in multiple sclerosis at 7 Tesla Background: Spinal cord is a major site of involvement in progressive MS.  ...  As R2* in WM depends also on the microstructural tissue orientation relative to the main magnetic field, the WM fibre orientation from the eigenvectors of a diffusion tensor imaging scan (TR/ TE=7465/75  ... 
doi:10.1177/1352458514547846 pmid:25205049 pmcid:PMC4244175 fatcat:gj757y4jlvejpnrfw22guoit7m

B - Scientific Sessions

2010 Insights into Imaging  
Results: In all patients, the entire pancreas was completely covered by the 16 cm scan field. Automatic image registration failed in two patients and manual adjustments were needed.  ...  Conclusion: Perfusion imaging of the whole pancreas allows for discrimination between changes in pancreatic oedema and necrosis in early phase of severe acute pancreatitis.  ...  Diffusion tensor imaging (tractography) was used for quantification of spinal white matter integrity (fractional anisotropy, FA) of whole spinal cord at C2-C3, C4-C5, and C6-C7 levels.  ... 
doi:10.1007/s13244-010-0011-1 pmid:23099631 pmcid:PMC3534347 fatcat:yfnq3lgteja2lfjl66ivdfnoum

Diffusion tensor imaging-based studies at the group-level applied to animal models of neurodegenerative diseases

Hans-Peter Müller, Francesco Roselli, Volker Rasche, Jan Rainer Kassubek, Universität Ulm
of diffusion tensor imaging (DTI).  ...  The translational aspect from in-vivo animal models toward (clinical) applications in humans is covered as well as the DTI-based research of the non-human brains' microstructure, the methodological aspects  ...  ACKNOWLEDGMENTS We would like to thank the Ulm University Center for Translational Imaging MoMAN for its support.  ... 
doi:10.18725/oparu-34051 fatcat:u5crd7rsmzb73f7vijpoex4luq

ECR 2011 Book of Abstracts - B - Scientific Sessions

2011 Insights into Imaging  
CT started 18 seconds after 140 HU threshold was reached in the abdominal aorta after intravenous contrast injection (370-400 mg I/mL, 4 mL/sec at 2 mL/kg followed by 50 mL of saline flush).  ...  Purpose: To compare the HCC nodule conspicuity during the arterial phase between contrast-enhanced 64-row multidetector CT with bolus tracking and MR imaging with bolus chase.  ...  High-field MRI scanners enable in vivo imaging of the lumen of the lenticulostriate arteries.  ... 
doi:10.1007/s13244-011-0077-4 pmid:23100071 pmcid:PMC3533624 fatcat:lytbu2vohbhhnorjqlpogl77iu

Athletic injuries of the extensor carpi ulnaris subsheath: MRI findings and utility of gadolinium-enhanced fat-saturated T1-weighted sequences with wrist pronation and supination

Jeremy Jeantroux, Fabio Becce, Henri Guerini, Bernard Montalvan, Dominique Le Viet, Jean-Luc Drapé
2010 European Radiology  
Purpose: To assess the rotation of the spinal cord and vertabra in axial planner using 3D-MRI in scoliosis patients.  ...  B-060 15:21 The application of diffusion tensor imaging in tumour of bone and soft tissue D.M. Deng 1 , Q.F.  ...  Purpose: The ability to objectively critique and assess the image quality of mammograms obtained by each department is vital to assess the efficacy of the services provided by breast imaging units.  ... 
doi:10.1007/s00330-010-1887-3 pmid:20680292 fatcat:c73xl4gmnjbp5hahuek6dg2pcu

Poster Session II

2012 Neuropsychopharmacology  
matter volumes, and (3) diffusion tensor imaging (DTI) to measure white matter microstructural integrity.  ...  Functional magnetic resonance imaging (fMRI) provides information about brain activity in cerebral regions of interest, and diffusion tensor imaging (DTI) measures the integrity of white matter tracts  ...  In a human in vivo structural MRI study, we assessed gray matter volume of intraparietal sulcus (IPS) as a function of genotype at rs13223593 in 279 healthy Caucasian subjects.  ... 
doi:10.1038/npp.2012.220 fatcat:coblfrtlujc6hdycjbnrdwzslm

ACRT-SCTS Scholar Abstracts

2010 Clinical and Translational Science  
OBJECTIVES: To assess the long term prediction of renal failure by serum uric acid levels in a longitudinal population study.  ...  We thus assessed the credibility of validated CAD polymorphisms in IS.  ...  In vivo, non-contact, ultra high resolution SD-OCT imaging was performed on day 0, day 1-2, day 5-6 and day 15-16 and day 21.  ... 
doi:10.1111/j.1752-8062.2010.00181_2.x fatcat:lwvd6nteozgezazejeqpjupawu


2017 Diabetes  
Methods: Changes in circulating spexin, body mass index (BMI), insulin resistance (HOMA-IR), total (T)-and high molecular weight (HMW)-adiponectin and leptin were measured longitudinally (baseline, 6-m  ...  outcome (CV death, non-fatal myocardial infarction and stroke) among 1,151 white subjects in the intensive BP arm of the ACCORD genetic substudy.  ...  Deletion of ILK in muscle or liver, respectively decreases insulin resistance in high fat diet (HFD)-fed mice.  ... 
doi:10.2337/db17-1-380 fatcat:fcp34ta7dbhc5dg747d3mepca4

Western Medical Research Conference 2017 ( Formerly Western Regional Meeting ) Camel, California, January 26–28, 2017

2016 Journal of Investigative Medicine  
Previous studies have shown boys with KS have a high percent body fat (%BF), but androgen supplementation in childhood is not standard of care.  ...  These combined with CT images showed right suprarenal mass with significant metastases to the liver led to the diagnosis of adrenocortical carcinoma (ACC). This was confirmed on liver biopsy.  ...  Previous studies have used diffusion tensor imaging (DTI) to detect white matter tract changes in regions of interest in symptomatic patients; however data in the pediatric population remains limited.  ... 
doi:10.1136/jim-2016-000365.1 fatcat:4g7yajiqd5evxalwbsmimjlzk4

Asia Pacific Stroke Conference 2016. Abstracts of the Annual Conference of theAsia Pacific Stroke Organization (APSO) Combined with Stroke Society of Australasia, Brisbane, Qld., Australia, July 14-17, 2016: Abstracts

2016 Cerebrovascular Diseases  
In this study we investigate the Gastrodia on the recovery of neurological function in rats of acute middle cerebral artery occlusion.  ...  Conclusion: Gastrodia can promote the recovery of neurological function, and has an effect on the proliferation of brain cells after acute infarction in MCAO rats.  ...  The fiber numbers asymmetry (FNA) scores based on diffusion tensor image tractography (DTI) were reduced in every OSC-treated subject.  ... 
doi:10.1159/000447732 pmid:27409083 fatcat:npg6lu4kgzherj7oa5aaory3lq

A Rare Case of Spontaneous Intestinal 34 Perforation at a Paediatric Emergency Department Chen, Lien A Chinese Family with Dominant 37 Deafness-onychodystrophy Syndrome HONG KONG JOURNAL OF PAEDIATRICS Hong Kong Journal of Paediatrics (New Series)

Yang, Yang, Huang, Medcom Limited Blank, Yiu Cheung, Associate Fai, Hon Chung, Lam Yin, San Hung, Ting Leung, Fan, Ching Chan (+31 others)
2018 unpublished
Calcineurin Inhibitors Functional and Ultrastructural Analysis of Respiratory Cilia in Healthy Chinese Children in Hong Kong  ...  Conflict of Interest All authors have no conflict of interest regarding this paper. Conflicts of Interest Statement The authors have no conflicts of interest relevant to this article.  ...  In addition, MRI scans of the three groups were analysed using voxel-based morphometry (VBM) and Diffusion tensor imaging (DTI).  ...