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LocusZoom.js: Interactive and embeddable visualization of genetic association study results

Andrew P Boughton, Ryan P Welch, Matthew Flickinger, Peter VandeHaar, Daniel Taliun, Gonçalo R Abecasis, Michael Boehnke
2021 Bioinformatics  
LocusZoom.js is a JavaScript library for creating interactive web-based visualizations of genetic association study results.  ...  Views can be customized and extended to display other data types such as phenome-wide association study (PheWAS) results, chromatin co-accessibility, or eQTL measurements.  ...  Conflict of Interest: G.R.A. is an employee of Regeneron Pharmaceuticals; he owns stock and stock options for Regeneron Pharmaceuticals.  ... 
doi:10.1093/bioinformatics/btab186 pmid:33734315 pmcid:PMC8479674 fatcat:gfensed7u5ej3ps3x6nkebht5i

LocusZoom.js: Interactive and embeddable visualization of genetic association study results [article]

Andrew P Boughton, Ryan P Welch, Matthew Flickinger, Peter VandeHaar, Daniel Taliun, Goncalo R Abecasis, Michael Boehnke
2021 bioRxiv   pre-print
LocusZoom.js is a JavaScript library for creating interactive web-based visualizations of genetic association study results.  ...  Views can be customized and extended to display other data types such as phenome-wide association study (PheWAS) results, chromatin co-accessibility, or eQTL measurements.  ...  Conflict of Interest: G.R.A. is an employee of Regeneron Pharmaceuticals; he owns stock and stock options for Regeneron Pharmaceuticals.  ... 
doi:10.1101/2021.01.01.423803 fatcat:dxkrkklypja6foa3ahwuu7fgta

ZEAMAP, a comprehensive database adapted to the maize multi-omics era [article]

Songtao Gui, Linfeng Yang, Jianbo Li, Jingyun Luo, Xiaokai Xu, Jianyu Yuan, Lu Chen, Wenqiang Li, Xin Yang, Shenshen Wu, Shuyan Li, Yuebin Wang (+4 others)
2020 bioRxiv   pre-print
ZEAMAP is user-friendly, with the ability to interactively integrate, visualize and cross-reference multiple different omics datasets.  ...  As one of the most extensively cultivated crops, maize (Zea mays L.) has been extensively studied by researchers and breeders for over a century.  ...  ACKNOWLEDGEMENTS The authors would like to thank Dr Qing Li and Ms Jing Xu (National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University) for providing the DNA methylation data  ... 
doi:10.1101/2020.01.04.894626 fatcat:f7rzhmwb6ffxdglnkzvfyksacy

ZEAMAP, a comprehensive database adapted to the maize multi-omics era

Songtao Gui, Linfeng Yang, Jianbo Li, Jingyun Luo, Xiaokai Xu, Jianyu Yuan, Lu Chen, Wenqiang Li, Xin Yang, Shenshen Wu, Shuyan Li, Yuebin Wang (+4 others)
2020 iScience  
ZEAMAP is user friendly, with the ability to interactively integrate, visualize, and cross-reference multiple different omics datasets.  ...  As one of the most extensively cultivated crops, maize (Zea mays L.) has been extensively studied by researchers and breeders for over a century.  ...  The search result lists general information of genetic and physical locations for each record, with physical locations linked to Jbrowse visualization (B).  ... 
doi:10.1016/j.isci.2020.101241 pmid:32629608 pmcid:PMC7306594 fatcat:6j5ihsfuf5c2hkfoave3cgrcci

PDE4B Proposed as a High Myopia Susceptibility Gene in Chinese Population

Fuxin Zhao, Wei Chen, Hui Zhou, Peter S. Reinach, Yuhan Wang, Suh-Hang H. Juo, Zhenglin Yang, Anquan Xue, Yi Shi, Chung-Ling Liang, Changqing Zeng, Jia Qu (+1 others)
2022 Frontiers in Genetics  
More studies are needed to determine if there is a correlation between PDE4B and high myopia in other larger sample sized cohorts.  ...  intron of phosphodiesterase 4B (PDE4B), whose functional assays were performed by comparing the effects of rs10889602T/T deletion of this risk allele on PDE4B and COL1A1 gene and protein expression levels  ...  LocusZoom.js: Interactive and Embeddable Visualization of Genetic Association Study Results.  ... 
doi:10.3389/fgene.2021.775797 pmid:35116054 pmcid:PMC8804583 fatcat:yb7druknjbbsbfsijyfj4rutae

Genetic Analysis of Right Heart Structure and Function in 40,000 People [article]

James P. Pirruccello, Paolo Di Achille, Victor Nauffal, Mahan Nekoui, Samuel N. Friedman, Marcus D. R. Klarqvist, Mark D. Chaffin, Shaan Khurshid, Carolina Roselli, Puneet Batra, Kenney Ng, Steven A. Lubitz (+4 others)
2021 bioRxiv   pre-print
Harnessing deep learning to perform large-scale cardiac phenotyping, our results yield insights into the genetic and clinical determinants of right heart structure and function.  ...  We then conducted genome-wide association studies, identifying 104 distinct loci associated with at least one right heart measurement.  ...  LocusZoom.js: Interactive and embeddable visualization of genetic association study results. bioRxiv 2021.01.01.423803 (2021) doi:10.1101/2021.01.01.423803. 37. Lonsdale, J. et al.  ... 
doi:10.1101/2021.02.05.429046 fatcat:snruehuymnct5h7qs7dam7hpua