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Local mechanical properties of white matter structures in the human brain
2013
NeuroImage
To date, brain MRE investigations have been limited to reporting global mechanical properties, though quantification of the stiffness of specific structures in the white matter architecture may be valuable ...
in assessing the localized effects of disease. ...
Kritzer Fund at the University of Illinois at Urbana-Champaign provided support for this work. CLJ acknowledges support from the Beckman Graduate Fellows Program of the Beckman Institute. ...
doi:10.1016/j.neuroimage.2013.04.089
pmid:23644001
pmcid:PMC3676712
fatcat:sjt6ogmto5e6tpw2xtoexe5ldm
A dynamic network perspective of chronic pain
2012
Neuroscience Letters
into persistent pain, and outline the role of mesolimbic learning mechanisms that are likely involved in maintenance of chronic pain. ...
Based on these observations and recent theoretical advances regarding network architecture properties, we develop a general concept of the dynamic interplay between anatomy and function as the brain progresses ...
Accordingly, the brain in chronic pain exhibits abnormalities in local grey matter and white matter restructuring, thereby degrading local networks but preserving large scale white matter tracks (Fig. ...
doi:10.1016/j.neulet.2012.05.001
pmid:22579823
pmcid:PMC3377811
fatcat:juyv5tmjfvayll6hofdynt3pga
Magnetic resonance elastography for examining developmental changes in the mechanical properties of the brain
2017
Developmental Cognitive Neuroscience
The measured mechanical properties reflect the microstructural composition and organization of neural tissue, and have shown significant effects in many neurological conditions and normal, healthy aging ...
The sensitivity of MRE to brain structure, function, and health make it an ideal technique for studying the developing brain; however, brain MRE studies on children and adolescents have only just begun ...
) from the National Institutes of Health and the State of Delaware, and from Delaware CTR ACCEL Program with a grant from the National Institutes of General Medical Sciences (U54-GM104941) from the National ...
doi:10.1016/j.dcn.2017.08.010
pmid:29239832
pmcid:PMC5832528
fatcat:thhwsdko5zekdjlmupkatak45a
Computational anatomy for studying use-dependant brain plasticity
2014
Frontiers in Human Neuroscience
In this article we provide a comprehensive literature review on the in vivo assessment of use-dependant brain structure changes in humans using magnetic resonance imaging (MRI) and computational anatomy ...
Given the current lack of in-depth understanding of the neurobiological basis of brain structure changes we emphasize the necessity of a paradigm shift in the investigation and interpretation of use-dependent ...
in underlying white matter architecture. ...
doi:10.3389/fnhum.2014.00380
pmid:25018716
pmcid:PMC4072968
fatcat:zutvf57sxjavfibsae6c6tjpbe
Mechanical properties of the in vivo adolescent human brain
2018
Developmental Cognitive Neuroscience
Viscoelastic mechanical properties of the in vivo human brain, measured noninvasively with magnetic resonance elastography (MRE), have recently been shown to be affected by aging and neurological disease ...
In this work, we characterized global and regional brain stiffness and damping ratio in a sample of 40 adolescents aged 12-14 years, including the lobes of the cerebrum and subcortical gray matter structures ...
Acknowledgments Support for this study was provided by NSF (SES-1459719), NIH/ NIDA (R01-DA039923), the Delaware INBRE Program (NIH/NIGMS P20-GM103446), the Delaware CTR ACCEL Program (NIH/NIGMS U54-GM104941 ...
doi:10.1016/j.dcn.2018.06.001
pmid:29906788
pmcid:PMC6289278
fatcat:cpsc47kq7vfdrlgsrffwpd7afy
The role of diffusion MRI in neuroscience
2017
NMR in Biomedicine
Figure 1: First drawings of white matter connection in the human brain. Left, brain dissection from Vieussens 3 and right, brain dissection from Johann Christian Reil 4 . ...
areas of the brain via their white matter connections. ...
This work was supported by the 'Agence Nationale de la Recherche' [grants number ANR-10-IAIHU-06 and number ANR-13-JSV4-0001-01]. ...
doi:10.1002/nbm.3762
pmid:28696013
fatcat:yq23ob4xibhxpfx4txsm664xci
On the Possible Shapes of the Brain
2012
Evolutionary biology
We discuss in particular the mechanisms of cortical folding and the relationship between folding and the structural and functional organisation of the brain. ...
Based on these phylogenetic and theoretical considerations, we turn to the analysis of the variability trends within humans: regional variations in grey and white matter volume and changes in cortical ...
Diversity of grey and white matter volumes in the frontal, parietal, occipital and temporal lobes among humans. ...
doi:10.1007/s11692-012-9201-8
fatcat:xp5j4b5su5bj7fqw72wvmlpecy
Human white matter and knowledge representation
2018
PLoS Biology
and local cortical circuitry) to the macroscale (brain cortical folding and white matter tracts) [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] . ...
Understanding how knowledge is represented in the human brain is a fundamental challenge in neuroscience. ...
McPherson for comments on early versions of this manuscript. ...
doi:10.1371/journal.pbio.2005758
pmid:29698391
pmcid:PMC5940236
fatcat:ttspqrukkvfk5cft4wd3abbygi
Time-harmonic magnetic resonance elastography of the normal feline brain
2010
Journal of Biomechanics
the recovered properties of grey and white matter. ...
Imaging of the mechanical properties of in vivo brain tissue could eventually lead to non-invasive diagnosis of hydrocephalus, Alzheimer's disease and other pathologies known to alter the intracranial ...
Grey and white matter is also better distinguished in the feline brain relative to other small animals, appearing more similarly to the human brain. ...
doi:10.1016/j.jbiomech.2010.06.008
pmid:20655045
pmcid:PMC2963725
fatcat:oo3a7ylxtjfr3bt5b2t2enzzvm
Combining the Finite Element Method with Structural Connectome-based Analysis for Modeling Neurotrauma: Connectome Neurotrauma Mechanics
2012
PLoS Computational Biology
We relate localized mechanical brain damage predicted from biofidelic finite element simulations of the human head subjected to impact with degradation in the structural connectome for a single individual ...
In the future, this computational framework could help inform functional networks from physics-based structural brain biomechanics to obtain not only a biomechanics-based understanding of injury, but also ...
are related to a decrease in localized white matter integrity. ...
doi:10.1371/journal.pcbi.1002619
pmid:22915997
pmcid:PMC3420926
fatcat:xpmfjcax6rf63oulz2v2atksaq
Correction: Combining the Finite Element Method with Structural Connectome-based Analysis for Modeling Neurotrauma: Connectome Neurotrauma Mechanics
2012
PLoS Computational Biology
We relate localized mechanical brain damage predicted from biofidelic finite element simulations of the human head subjected to impact with degradation in the structural connectome for a single individual ...
In the future, this computational framework could help inform functional networks from physics-based structural brain biomechanics to obtain not only a biomechanics-based understanding of injury, but also ...
are related to a decrease in localized white matter integrity. ...
doi:10.1371/annotation/fd39b102-fb25-4ff2-9907-07af01ea6801
fatcat:jbxua5tbjne6xa2kmvo6ftnuym
Imaging structural co-variance between human brain regions
2013
Nature Reviews Neuroscience
Brain structure varies between people in a markedly organized fashion. Communities of brain regions co-vary in their morphological properties. ...
This Review discusses the state of current research into brain structural co-variance, its underlying mechanisms and its potential value in the understanding of various neurological and psychiatric conditions ...
white matter links, owing to indirect or emergent properties of white matter networks 34,35,218,219 . ...
doi:10.1038/nrn3465
pmid:23531697
pmcid:PMC4043276
fatcat:k2iuznauebdw3ibxu7f7l67co4
The Role Of Diffusion MRI In Neuroscience
[article]
2017
bioRxiv
pre-print
Diffusion weighted imaging has further pushed the boundaries of neuroscience by allowing us to peer farther into the white matter microstructure of the living human brain. ...
We will briefly summarise key questions, that have historically been raised in neuroscience, concerning the brain's white matter. ...
This work was supported by the 'Agence Nationale de la Recherche' [grants number ANR-10-IAIHU-06 and number ANR-13-JSV4-0001-01]. ...
doi:10.1101/140459
fatcat:jjianciqojbtpmafzpkxkkqivm
Advances in multimodal magnetic resonance imaging of vascular mild cognitive impairment
2019
Journal of Hainan Medical University
As a widely used imaging method, multimode magnetic resonance imaging can evaluate the brain structure and function of patients with VaMCI noninvasively and explore the relationship between brain structure ...
It is beneficial to provide an idea for early diagnosis of VaMCI and to further understand the neuropathologic mechanism of its occurrence, which has broad application prospects.In this paper, the research ...
Topological structure of brain network based on graph theory In recent years, humans have found that the brain has extraordinary topological properties, such as small-world attributes and short path length ...
doaj:8362f89dd33d48d2abc6e8a07c608b8f
fatcat:3x3tsryp6jdyvpyyrtxlrrj6pi
Hemispheric Asymmetry of Human Brain Anatomical Network Revealed by Diffusion Tensor Tractography
2015
BioMed Research International
Furthermore, local structural connections were also investigated to examine the local asymmetries of some specific white matter tracts. ...
The topological architecture of the cerebral anatomical network reflects the structural organization of the human brain. ...
Moreover, the structural properties of some local white matter tracts also exhibit hemispheric asymmetries, which indicated the asymmetries of local connections. ...
doi:10.1155/2015/908917
pmid:26539535
pmcid:PMC4619913
fatcat:npcfpqe7mzemrhib6pwt5gj6ze
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