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Asian-Pacific Association for the Study of the Liver (APASL) consensus guidelines on invasive and non-invasive assessment of hepatic fibrosis: a 2016 update

Gamal Shiha, Alaa Ibrahim, Ahmed Helmy, Shiv Kumar Sarin, Masao Omata, Ashish Kumar, David Bernstien, Hitushi Maruyama, Vivek Saraswat, Yogesh Chawla, Saeed Hamid, Zaigham Abbas (+21 others)
2016 Hepatology International  
Hepatic fibrosis is a common pathway leading to liver cirrhosis, which is the end result of any injury to the liver.  ...  Computer-assisted image analysis of histochemically stained sections is a method for measuring fibrosis morphologically.  ...  between pathologists [55] .  ... 
doi:10.1007/s12072-016-9760-3 pmid:27714681 fatcat:eifh6pkgajabtlcvzt7rgcm7by

Track F

2014 Biomedical Engineering  
Abstract In this study we investigated the potential of NIRS for the intra-operative quantification of fat content in the liver of rats with differing degree of hepatic steatosis using a fiber coupled  ...  Additionally, a framework for the implementation of workflow-driven assistance based on knowledge-based systems and distributed structure is described.  ...  Acknowledgement This work was partly promoted by funds of the European Regional Development Fund (ERDF) and the European Social Fund (ESF) within the scope of the combined research between economy and  ... 
doi:10.1515/bmt-2014-5005 pmid:25385890 fatcat:7ubf3s5qgrd6zjtsrvzxhhb7gu

Techniques

2016 Laboratory Investigation  
This could be due to an innately poor ability to resolve differences in hue (H) when the intensity (I) is very low.  ...  There was a statistically significant difference (p=0.0179) between HI and IS using the Ettinger ratio (MA/r+K).  ...  the computer during and after after image analysis.  ... 
doi:10.1038/labinvest.2016.24 pmid:26813186 fatcat:pdkbstlctbdexei3pye55r2ydm

AASLD Abstracts 895-1142

2008 Hepatology  
Spearman rank correlation was used to evaluate the association between liver stiffness and liver histology.  ...  The serum HBV-DNA level has been shown to be correlated with progression of the disease.  ...  With respect to the cases selected for analysis, the ballooning score differed between the individual local pathologist and the group review by 2 points in 11 cases and by 1 point in 7 cases.  ... 
doi:10.1002/hep.22644 fatcat:npjzzrmvg5hvxlupppcl2qrnou

ECR 2011 Book of Abstracts - B - Scientific Sessions

2011 Insights into Imaging  
Purpose: To compare the HCC nodule conspicuity during the arterial phase between contrast-enhanced 64-row multidetector CT with bolus tracking and MR imaging with bolus chase.  ...  The contrast-to-noise ratio (CNR) on CT [(Attenuation nodule -Attenuation liver )/(SD background)x100], and MR imaging [[(Intensity nodule -Intensity liver )/(SD background)x100] were calculated and compared  ...  For quantitative analysis of tumour-vasculature dedicated computer-assisted-diagnosis software was used.  ... 
doi:10.1007/s13244-011-0077-4 pmid:23100071 pmcid:PMC3533624 fatcat:lytbu2vohbhhnorjqlpogl77iu

Techniques

2006 Modern Pathology  
A linear correlation was obtained between ACIS scores and manual scoring categories.  ...  of tedium and eliminating the conventional 10 H.P.F.s sample bias.  ...  This is mainly due to the type of reagents used in the conventional fixation and processing.  ... 
doi:10.1038/sj.modpathol.3800858 fatcat:ktkjy3udl5cbtgconpfjhhkkam

IAFS 2017 Abstracts

2017 Forensic Science International  
ASSOCIATION BETWEEN SCN5A GENE AND SUDDEN UNEXPLAINED NOCTURNAL DEATH SYNDROME IN THAI CADAVERS Disclosure: All authors have declared no conflicts of interest.  ...  RECOVERY OF FINGERMARKS FROM METALLIC SURFACES USING A SCANNING KELVIN PROBE Disclosure: All authors have declared no conflicts of interest.  ...  The aim was to produce sets which would provide size differences detectable with gel-based systems and qPCR, in addition to the conventional fluorescence-based detection on automatic sequencers.  ... 
doi:10.1016/j.forsciint.2017.07.019 pmid:28743352 fatcat:pdrympkytzbzlkah4vnqismhau

Why Should Young Doctors Choose to Become Surgeons?

Peter Neuhaus
2007 Annals of Surgery  
Preoperative evaluation of Glasgow prognostic score, an inflammation-based prognostic score that includes simply C-reactive protein and albumin, is considered to be a useful predictor of postoperative  ...  Mortality was influenced by different risk factors, including type of surgery, open surgery, prolonged operative time, comorbidities, and hospital volume of activity.  ...  ACKNOWLEDGMENTS The authors thank the participants of our survey at the Annual Meeting of the European Surgical Association in ACKNOWLEDGMENTS The authors thank the many participants and research personnel  ... 
doi:10.1097/sla.0b013e31815c29ed pmid:18043091 fatcat:pyfs3bimxnahvjdoq45jw2rgqy

AASLD Abstract (pp. 162A–266A)

2004 Hepatology  
Down-regulation of hepcidin expression by ethanol in vivo may lead to systemic iron overload due to up-regulation of intestinal iron absorption and of iron release from macrophages.  ...  These findings imply a role for hepcidin in the pathogenesis of ALD, and the accumulation of hepatic iron in ALD. The following authors have indicated they have no relationships to disclose:  ...  Aim: To examine if the degree of hepatic steatosis as graded by pathologists correlates with the hepatic TG content in human liver tissue.  ... 
doi:10.1002/hep.1840400507 fatcat:qpbtmnqfrjd7bf3jxjypw73oji

Noninvasive Diagnostic and Prognostic Assessment Tools for Liver Fibrosis and Cirrhosis in Patients with Chronic Liver Disease [chapter]

Ju‐Seop Kang, Min‐Ho Lee
2017 Liver Cirrhosis - Update and Current Challenges  
Although invasive liver biopsy is the gold standard to assess the nature and severity of hepatic fibrosis, it has several recognized limitations including sampling error and inter-observer variability  ...  The aims of this chapter were to review the nature and limitations of the several noninvasive methods for the assessment of presence and severity of liver fibrosis in patients with chronic liver disease  ...  The AUROC Pros • Gold standard to assess fibrosis • Direct observation and quantitative assessment of fibrosis, inflammation, and steatosisDifferent stage by different scoring systems • Diagnosing different  ... 
doi:10.5772/intechopen.68317 fatcat:w77uzxjwn5hr3jy7s26a3fjvgy

Abstract

2021 Hepatology International  
effective in the treatment of chronic hepatitis B (CHB) due to its Dr Zhihong Liu1, Prof Yuexin Zhang2, Prof Guozhong Gong3, capability to reduce hepatitis B surface antigen (HBsAg) and hepatitis  ...  of hepatitis B surface antigen candidate.  ... 
doi:10.1007/s12072-021-10213-7 fatcat:5w6v5add7vgbdih5vm2tazglni

B - Scientific Sessions

2010 Insights into Imaging  
Purpose: To evaluate perfusion differences between oedemic and necrotic pancreatic tissue in patients with initial stage of acute pancreatitis using 320-slice dynamic volume CT.  ...  The perfusion values of normal pancreatic tissue ranged from 0.67 to 2.37 min -1 , in pancreatic oedema between 0.30 to 0.89 min -1 . No perfusion was noted in necrotic tissue areas.  ...  Meta-analysis was therefore precluded. MRS showed best results for discriminating between different degrees of hepatic steatosis.  ... 
doi:10.1007/s13244-010-0011-1 pmid:23099631 pmcid:PMC3534347 fatcat:yfnq3lgteja2lfjl66ivdfnoum

ESGAR 2020 Book of Abstracts

2020 Insights into Imaging  
Purpose: To assess the performance of liver surface nodularity (LSN) quantification for the differentiation between porto-sinusoidal vascular disease (PSVD) and cirrhosis.  ...  Diameter, margin, hepatic metastasis and ratio of tumor to pancreatic parenchyma in AP were significantly different between G1 and G2/3 PNEN.  ... 
doi:10.1186/s13244-020-00873-8 pmid:32419107 fatcat:jnt6ow5qljejvcyo257fgdwpbe

20th ECP

2005 Virchows Archiv  
These preliminary data showed no significant variations of the intratumoral stroma and capillaries amounts in different areas of ductal invasive breast carcinomas and also no significant correlation between  ...  The authors made a preliminary assessement of possible correlations between the amount of fibrillary components and capillary network of intratumoral stroma and the degree of glandular formation in 20  ...  ALT and triglycerides were significantly higher in NASH than SS with positive correlation between their levels and histopathological scoring of hepatic steatosis.  ... 
doi:10.1007/s00428-005-1288-1 fatcat:25f45fdp5ffvdlo25zaqkddywm

Summer Meeting 2010. 198th Scientific Meeting of the Pathological Society of Great Britain & Ireland, 29 June-1 July

2010 Journal of Pathology  
Acknowledgments (Trade Exhibition) as at time of going to press Poster Abstracts Presenter = P  ...  To examine the difference of tumourigenicity between S and M cells in L1236 cells, limiting dilution, semi-solid cultures, and injection into nonobese diabetic/severe combined immunodeficiency (NOD/SCID  ...  Spearman correlation of matched pairs between first and later years showed no significant increase in scores for deep and strategic and a slight but not significant fall in surface.  ... 
doi:10.1002/path.2770 pmid:21157838 fatcat:go5nqlpxnjatddy7le4gqqfcxe
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